Hydrazonoyl halides as precursors for new fused heterocycles of 5α-reductase inhibitors

Archiv der Pharmazie

Volumn 345, Issue 2, 2012, Pages 117-122

  Farghaly, Thoraya A ^a   Gomha, Sobhi M ^a   Abbas, Eman M H ^b   Abdalla, Mohamed M ^c  

^a CAIRO UNIVERSITY   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

^c MAPCO Pharmaceuticals Ltd   (Egypt)

Author keywords

5 Reductase inhibitors; Benzo 6,7 cyclohepta 1,2 d thiazolo 3,2 a pyrimidin 3 ones; Benzo 6,7 cyclohepta 1,2 d triazolo 4,3 a pyrimidines; Hydrazonoyl halides

Indexed keywords

1,3 DIPHENYL 1,5,6,7,8 PENTAHYDRO 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 2 ARYLIDINE BENZO[6,7]CYCLOHEPTA[1,2 D]THIAZOLO[3,2 A]PYRIMIDINE 3 ONE; 3 (2 NAPHTHOYL) 1,5,6,7,8 PENTAHYDRO 1 PHENYL 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 (2 THIENYL) 1,5,6,7,8 PENTAHYDRO 1 (4 NITROPHENYL) 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 ACETYL 1,5,6,7,8 PENTAHYDRO 1 (4 CHLOROPHENYL) 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 ACETYL 1,5,6,7,8 PENTAHYDRO 1 (4 METHYLPHENYL) 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[2,1 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 ACETYL 1,5,6,7,8 PENTAHYDRO 1 PHENYL 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 BENZOYL 1,5,6,7,8 PENTAHYDRO 1 PHENYL 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 ETHOXYCARBONYL 1,5,6,7,8 PENTAHYDRO 1 (4 CHLOROPHENYL) 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 ETHOXYCARBONYL 1,5,6,7,8 PENTAHYDRO 1 (4 METHYLPHENYL) 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 ETHOXYCARBONYL 1,5,6,7,8 PENTAHYDRO 1 PHENYL 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 PHENYLCARBAMOYL 1,5,6,7,8 PENTAHYDRO 1 (4 CHLOROPHENYL) 5 (4 METHOXY PHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 3 PHENYLCARBAMOYL 1,5,6,7,8 PENTAHYDRO 1 PHENYL 5 (4 METHOXYPHENYL)BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; 4 (4 METHOXYPHENYL) 1,3,4,5,6,7 HEXAHYDRO 2 THIOXO BENZO[6,7]CYCLOHEPTA[1,2 D]PYRIMIDINE; 4 (4 METHOXYPHENYL) 3,4,5,6,7 PENTAHYDRO 2 METHYLTHIO BENZO[6,7]CYCLOHEPTA[1,2 D]PYRIMIDINE; 5 (4 METHOXYPHENYL) 2,5,6,7,8 PENTAHYDROBENZO[6,7]CYCLOHEPTA[1,2 D]THIAZOLO[3,2 A]PYRIMIDINE 3 ONE; ALDEHYDE; ANASTROZOLE; BENZO[6,7]CYCLOHEPTA[1,2 D]THIAZOLO[3,2 A]PYRIMIDIN 3 ONE; BENZO[6,7]CYCLOHEPTA[1,2 D]TRIAZOLO[4,3 A]PYRIMIDINE; CHLOROACETIC ACID; HALIDE; HYDRAZONOYL HALIDE; STEROID 5ALPHA REDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MICROANALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SPECTROSCOPY;

5-ALPHA REDUCTASE INHIBITORS; ANIMALS; HETEROCYCLIC COMPOUNDS; HYDRAZONES; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84856359747     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201100212     Document Type: Article

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