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Volumn 16, Issue 2, 2012, Pages 386-393

STAT1 deficiency in the heart protects against myocardial infarction by enhancing autophagy

Author keywords

Autophagy; Cardioprotection; Ischaemia; STAT1

Indexed keywords

3 METHYLADENINE; 3-METHYLADENINE; ADENINE; APG12L PROTEIN, MOUSE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, MOUSE; CARDIOTONIC AGENT; DRUG DERIVATIVE; MICROTUBULE ASSOCIATED PROTEIN; PROTEIN; PROTEIN P53; STAT1 PROTEIN; STAT1 PROTEIN, MOUSE;

EID: 84856347915     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2011.01323.x     Document Type: Article
Times cited : (73)

References (31)
  • 1
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: molecular mechanisms and biological functions of autophagy
    • Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell. 2004; 6: 463-77.
    • (2004) Dev Cell. , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 2
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: a history of macroautophagy
    • Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol. 2010; 12: 814-822.
    • (2010) Nat Cell Biol. , vol.12 , pp. 814-822
    • Yang, Z.1    Klionsky, D.J.2
  • 3
    • 11144245626 scopus 로고    scopus 로고
    • The role of autophagy during the early neonatal starvation period
    • Kuma A, Hatano M, Matsui M, et al The role of autophagy during the early neonatal starvation period. Nature. 2004; 432: 1032-6.
    • (2004) Nature. , vol.432 , pp. 1032-1036
    • Kuma, A.1    Hatano, M.2    Matsui, M.3
  • 4
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy:dual roles in life and death
    • Baehrecke EH. Autophagy:dual roles in life and death. Nat Rev Mol Cell Biol. 2005; 6: 505-10.
    • (2005) Nat Rev Mol Cell Biol. , vol.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 5
    • 0030249340 scopus 로고
    • Acute myocardial infarction in humans is associated with the activation of programmed myocyte cell death in the surviving portion of the heart
    • Olivevetti G, Quani F, Sala R, et al. Acute myocardial infarction in humans is associated with the activation of programmed myocyte cell death in the surviving portion of the heart. J Mol Cell Cardiol. 1994; 28: 2005-16.
    • (1994) J Mol Cell Cardiol. , vol.28 , pp. 2005-2016
    • Olivevetti, G.1    Quani, F.2    Sala, R.3
  • 6
    • 0035902545 scopus 로고    scopus 로고
    • Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischaemia/reperfusion injury
    • Scarabelli TM, Stephanou A, Rayment NB, et al Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischaemia/reperfusion injury. Circulation. 2001; 104: 253-6.
    • (2001) Circulation. , vol.104 , pp. 253-256
    • Scarabelli, T.M.1    Stephanou, A.2    Rayment, N.B.3
  • 7
    • 0037023636 scopus 로고    scopus 로고
    • Different signalling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischaemia/reperfusion injury
    • Scarabelli TM, Stephanou A, Pasini E, et al Different signalling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischaemia/reperfusion injury. Circ Res. 2002; 90: 745-8.
    • (2002) Circ Res. , vol.90 , pp. 745-748
    • Scarabelli, T.M.1    Stephanou, A.2    Pasini, E.3
  • 8
    • 34447133404 scopus 로고    scopus 로고
    • Cardiac autophagy is a maladaptive response to hemodynamic stress
    • Zhu H, Tannous P, Johnstone JL, et al Cardiac autophagy is a maladaptive response to hemodynamic stress. J Clin Invest. 2007; 117: 1782-93.
    • (2007) J Clin Invest. , vol.117 , pp. 1782-1793
    • Zhu, H.1    Tannous, P.2    Johnstone, J.L.3
  • 9
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y, Takagi H, Qu X, et al Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res. 2007; 100: 914-22.
    • (2007) Circ Res. , vol.100 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3
  • 10
    • 77951901715 scopus 로고    scopus 로고
    • Cell death in the pathogenesis of heart disease: mechanisms and significance
    • Whelan RS, Kaplinskiy V, Kitsis RN. Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol. 2010; 72: 19-44.
    • (2010) Annu Rev Physiol. , vol.72 , pp. 19-44
    • Whelan, R.S.1    Kaplinskiy, V.2    Kitsis, R.N.3
  • 11
    • 0036731485 scopus 로고    scopus 로고
    • Stats: transcriptional control and biological impact
    • Levy DE, Darnell JE Jr. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol. 2002; 3: 651-62.
    • (2002) Nat Rev Mol Cell Biol. , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr, J.E.2
  • 12
    • 0034616164 scopus 로고    scopus 로고
    • Ischaemia-induced STAT1 expression and activation plays a critical role in cardiac myocyte apoptosis
    • Stephanou A, Brar B, Knight RA, et al Ischaemia-induced STAT1 expression and activation plays a critical role in cardiac myocyte apoptosis. J Biol Chem. 2000; 275: 10002-8.
    • (2000) J Biol Chem. , vol.275 , pp. 10002-10008
    • Stephanou, A.1    Brar, B.2    Knight, R.A.3
  • 13
    • 16644379560 scopus 로고    scopus 로고
    • Role of STAT-1 and STAT-3 in ischaemia/reperfusion injury
    • Stephanou A. Role of STAT-1 and STAT-3 in ischaemia/reperfusion injury. J Cell Mol Med. 2004; 8: 519-25.
    • (2004) J Cell Mol Med. , vol.8 , pp. 519-525
    • Stephanou, A.1
  • 14
    • 13344282731 scopus 로고    scopus 로고
    • Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
    • Meraz MA, White JM, Sheehan KC, et al Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell. 1996; 84: 431-42.
    • (1996) Cell. , vol.84 , pp. 431-442
    • Meraz, M.A.1    White, J.M.2    Sheehan, K.C.3
  • 15
    • 4043082106 scopus 로고    scopus 로고
    • Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning
    • Smith RM, Suleman N, Lacerda L, et al Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning. Cardiovasc Res. 2004; 63: 611-6.
    • (2004) Cardiovasc Res. , vol.63 , pp. 611-616
    • Smith, R.M.1    Suleman, N.2    Lacerda, L.3
  • 16
    • 9444271638 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis
    • Townsend PA, Scarabelli TM, Pasini E, et al Epigallocatechin-3-gallate inhibits STAT-1 activation and protects cardiac myocytes from ischemia/reperfusion-induced apoptosis. FASEB J. 2004; 18: 1621-3.
    • (2004) FASEB J. , vol.18 , pp. 1621-1623
    • Townsend, P.A.1    Scarabelli, T.M.2    Pasini, E.3
  • 17
    • 66349135140 scopus 로고    scopus 로고
    • Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters
    • Ju JS, Miller SE, Jackson E, et al Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters. Autophagy. 2010; 5: 511-9.
    • (2010) Autophagy. , vol.5 , pp. 511-519
    • Ju, J.S.1    Miller, S.E.2    Jackson, E.3
  • 18
    • 0033973020 scopus 로고    scopus 로고
    • Cellular and molecular dissection of reperfusion injury: ROS within and without
    • Semenza GL. Cellular and molecular dissection of reperfusion injury: ROS within and without. Circ Res. 2000; 86: 117-8.
    • (2000) Circ Res. , vol.86 , pp. 117-118
    • Semenza, G.L.1
  • 19
    • 0032416113 scopus 로고    scopus 로고
    • Activation of the JAK-STAT pathway by reactive oxygen species
    • Simon AR, Rai U, Fanburg BL, et al Activation of the JAK-STAT pathway by reactive oxygen species. Am J Physiol. 1998; 275: 1640-52.
    • (1998) Am J Physiol. , vol.275 , pp. 1640-1652
    • Simon, A.R.1    Rai, U.2    Fanburg, B.L.3
  • 20
    • 33845681986 scopus 로고    scopus 로고
    • Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury
    • McCormick J, Barry SP, Sivarajah A, et al Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury. FASEB J. 2006; 20: 2115-7.
    • (2006) FASEB J. , vol.20 , pp. 2115-2117
    • McCormick, J.1    Barry, S.P.2    Sivarajah, A.3
  • 21
    • 84864290306 scopus 로고    scopus 로고
    • IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy
    • e4588
    • Al-Zeer MA, Al-Younes HM, Braun PR, et al IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy. PLoS One. 2009; 4: e4588, 1-13.
    • (2009) PLoS One , vol.4 , pp. 1-13
    • Al-Zeer, M.A.1    Al-Younes, H.M.2    Braun, P.R.3
  • 22
    • 77956508417 scopus 로고    scopus 로고
    • Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation
    • Chang YP, Tsai CC, Huang WC, et al Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation. J Biol Chem. 2010; 285: 28715-22.
    • (2010) J Biol Chem. , vol.285 , pp. 28715-28722
    • Chang, Y.P.1    Tsai, C.C.2    Huang, W.C.3
  • 24
    • 0036476551 scopus 로고    scopus 로고
    • Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling
    • Ramana CV, Gil MP, Schreiber RD, et al Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling. Trends Immunol. 2002; 23: 96-101.
    • (2002) Trends Immunol. , vol.23 , pp. 96-101
    • Ramana, C.V.1    Gil, M.P.2    Schreiber, R.D.3
  • 25
    • 58649117965 scopus 로고    scopus 로고
    • Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury
    • Scarabelli TM, Mariotto S, Abdel-Azeim S, et al Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion-induced injury. FEBS Lett. 2009; 583: 531-41.
    • (2009) FEBS Lett. , vol.583 , pp. 531-541
    • Scarabelli, T.M.1    Mariotto, S.2    Abdel-Azeim, S.3
  • 26
    • 38349041956 scopus 로고    scopus 로고
    • Protective effect of epigallocatechin-3-gallate on ischemia/reperfusion-induced injuries in the heart: STAT1 silencing flavonoid
    • Darra E, Shoji K, Mariotto S, et al Protective effect of epigallocatechin-3-gallate on ischemia/reperfusion-induced injuries in the heart: STAT1 silencing flavonoid. Genes Nutr. 2007; 2: 307-10.
    • (2007) Genes Nutr. , vol.2 , pp. 307-310
    • Darra, E.1    Shoji, K.2    Mariotto, S.3
  • 27
    • 78649630983 scopus 로고    scopus 로고
    • Resveratrol and cardiovascular health
    • Das M, Das DK. Resveratrol and cardiovascular health. Mol Aspects Med. 2010; 31: 503-12.
    • (2010) Mol Aspects Med. , vol.31 , pp. 503-512
    • Das, M.1    Das, D.K.2
  • 28
    • 33847271089 scopus 로고    scopus 로고
    • Coping with stress: multiple ways to activate p53
    • Horn HF, Vousden KH. Coping with stress: multiple ways to activate p53. Oncogene. 2007; 26: 1306-16.
    • (2007) Oncogene. , vol.26 , pp. 1306-1316
    • Horn, H.F.1    Vousden, K.H.2
  • 29
    • 33745885329 scopus 로고    scopus 로고
    • DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
    • Crighton D, Wilkinson S, O'Prey J, et al DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell. 2006; 126: 121-34.
    • (2006) Cell. , vol.126 , pp. 121-134
    • Crighton, D.1    Wilkinson, S.2    O'Prey, J.3
  • 30
    • 44649141966 scopus 로고    scopus 로고
    • Regulation of autophagy by cytoplasmic p53
    • Tasdemir E, Maiuri MC, Galluzzi L, et al Regulation of autophagy by cytoplasmic p53. Nat Cell Biol. 2008; 10: 676-87.
    • (2008) Nat Cell Biol. , vol.10 , pp. 676-687
    • Tasdemir, E.1    Maiuri, M.C.2    Galluzzi, L.3
  • 31
    • 1242316989 scopus 로고    scopus 로고
    • STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis
    • Townsend PA, Scarabelli TM, Davidson SM, et al STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis. J Biol Chem. 2004; 279: 5811-20.
    • (2004) J Biol Chem. , vol.279 , pp. 5811-5820
    • Townsend, P.A.1    Scarabelli, T.M.2    Davidson, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.