메뉴 건너뛰기




Volumn 39, Issue 2, 2012, Pages 279-285

Characterization of 4-[ 18F]-ADAM as an imaging agent for SERT in non-human primate brain using PET: A dynamic study

Author keywords

Biodistribution; Brain; Nonhuman primate or monkey; PET; Serotonin transporter; Transit time

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; FLUOXETINE; N,N DIMETHYL 2 (2 AMINO 4 FLUOROPHENYLTHIO)BENZYLAMINE F 18; RADIOPHARMACEUTICAL AGENT; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; BENZYLAMINE DERIVATIVE; FLUORINE; N,N DIMETHYL 2 (2 AMINO 4 FLUOROPHENYLTHIO)BENZYLAMINE; N,N-DIMETHYL-2-(2-AMINO-4-FLUOROPHENYLTHIO)BENZYLAMINE; SEROTONIN RECEPTOR AFFECTING AGENT; SEROTONIN UPTAKE INHIBITOR;

EID: 84856343269     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2011.08.002     Document Type: Article
Times cited : (32)

References (33)
  • 1
    • 0036123041 scopus 로고    scopus 로고
    • How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy?
    • Kish S.J. How strong is the evidence that brain serotonin neurons are damaged in human users of ecstasy?. Pharmacol Biochem Behav 2002, 71:845-855.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 845-855
    • Kish, S.J.1
  • 3
    • 0033838035 scopus 로고    scopus 로고
    • A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide
    • Mann J.J., Huang Y.Y., Underwood M.D., Kassir S.A., Oppenheim S., Kelly T.M., et al. A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide. Arch Gen Psychiatry 2000, 57:729-738.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 729-738
    • Mann, J.J.1    Huang, Y.Y.2    Underwood, M.D.3    Kassir, S.A.4    Oppenheim, S.5    Kelly, T.M.6
  • 4
    • 0031944188 scopus 로고    scopus 로고
    • Serotonin in aging, late-life depression, and Alzheimer's disease: the emerging role of functional imaging
    • Meltzer C.C., Smith G., DeKosky S.T., Pollock B.G., Mathis C.A., Moore R.Y., et al. Serotonin in aging, late-life depression, and Alzheimer's disease: the emerging role of functional imaging. Neuropsychopharmacology 1998, 18:407-430.
    • (1998) Neuropsychopharmacology , vol.18 , pp. 407-430
    • Meltzer, C.C.1    Smith, G.2    DeKosky, S.T.3    Pollock, B.G.4    Mathis, C.A.5    Moore, R.Y.6
  • 5
    • 0345540627 scopus 로고    scopus 로고
    • Autoregulation of serotonin neurons: role in antidepressant drug action
    • Pineyro G., Blier P. Autoregulation of serotonin neurons: role in antidepressant drug action. Pharmacol Rev 1999, 51:533-591.
    • (1999) Pharmacol Rev , vol.51 , pp. 533-591
    • Pineyro, G.1    Blier, P.2
  • 6
    • 0030754230 scopus 로고    scopus 로고
    • Antidepressants
    • Frazer A. Antidepressants. J Clin Psychiatry 1997, 58:9-25.
    • (1997) J Clin Psychiatry , vol.58 , pp. 9-25
    • Frazer, A.1
  • 8
    • 0033938105 scopus 로고    scopus 로고
    • Neurotransmitter transporters: fruitful targets for CNS drug discovery
    • Iversen L. Neurotransmitter transporters: fruitful targets for CNS drug discovery. Mol Psychiatry 2001, 5:357-362.
    • (2001) Mol Psychiatry , vol.5 , pp. 357-362
    • Iversen, L.1
  • 9
    • 44949283567 scopus 로고
    • Citalopram: labelling with carbon-11 and evaluation in rat as a potential radioligand for in vivo PET studies of 5-HT re-uptake sites
    • Hume S.P., Pascali C., Pike V.W., Turton D.R., Ahier R.G., Myers R., et al. Citalopram: labelling with carbon-11 and evaluation in rat as a potential radioligand for in vivo PET studies of 5-HT re-uptake sites. Int J Rad Appl Instrum B 1991, 18:339-351.
    • (1991) Int J Rad Appl Instrum B , vol.18 , pp. 339-351
    • Hume, S.P.1    Pascali, C.2    Pike, V.W.3    Turton, D.R.4    Ahier, R.G.5    Myers, R.6
  • 11
    • 44949283474 scopus 로고
    • Radiosynthesis and evaluation of N-(3-[18F]fluoropropyl)paroxetine as a radiotracer for in vivo labeling of serotonin uptake sites by PET
    • Suehiro M., Wilson A.A., Scheffel U., Dannals R.F., Ravert H.T., Wagner H.N. Radiosynthesis and evaluation of N-(3-[18F]fluoropropyl)paroxetine as a radiotracer for in vivo labeling of serotonin uptake sites by PET. Int J Rad Appl Instrum B 1991, 18:791-796.
    • (1991) Int J Rad Appl Instrum B , vol.18 , pp. 791-796
    • Suehiro, M.1    Wilson, A.A.2    Scheffel, U.3    Dannals, R.F.4    Ravert, H.T.5    Wagner, H.N.6
  • 12
    • 34648831594 scopus 로고    scopus 로고
    • Neuroimaging of the serotonin reuptake site requires high-affinity ligands
    • Elfving B., Madsen J., Knudsen G.M. Neuroimaging of the serotonin reuptake site requires high-affinity ligands. Synapse 2007, 61:882-888.
    • (2007) Synapse , vol.61 , pp. 882-888
    • Elfving, B.1    Madsen, J.2    Knudsen, G.M.3
  • 13
    • 0029036521 scopus 로고
    • Positron emission tomography imaging of serotonin transporters in the human brain using [11C](+)McN5652
    • Szabo Z., Kao P.F., Scheffel U., Suehiro M., Mathews W.B., Ravert H.T., et al. Positron emission tomography imaging of serotonin transporters in the human brain using [11C](+)McN5652. Synapse 1995, 20:37-43.
    • (1995) Synapse , vol.20 , pp. 37-43
    • Szabo, Z.1    Kao, P.F.2    Scheffel, U.3    Suehiro, M.4    Mathews, W.B.5    Ravert, H.T.6
  • 14
    • 2542492338 scopus 로고    scopus 로고
    • Comparative evaluation of serotonin transporter radioligands 11C-DASB and 11C-McN 5652 in healthy humans
    • Frankle W.G., Huang Y., Hwang D.R., Talbot P.S., Slifstein M., Van Heertum R., et al. Comparative evaluation of serotonin transporter radioligands 11C-DASB and 11C-McN 5652 in healthy humans. J Nucl Med 2004, 45:682-694.
    • (2004) J Nucl Med , vol.45 , pp. 682-694
    • Frankle, W.G.1    Huang, Y.2    Hwang, D.R.3    Talbot, P.S.4    Slifstein, M.5    Van Heertum, R.6
  • 15
    • 0033796913 scopus 로고    scopus 로고
    • In vivo quantification of brain serotonin transporters in humans using [11C]McN 5652
    • Parsey R.V., Kegeles L.S., Hwang D.R., Simpson N., Abi-Dargham A., Mawlawi O., et al. In vivo quantification of brain serotonin transporters in humans using [11C]McN 5652. J Nucl Med 2000, 41:1465-1477.
    • (2000) J Nucl Med , vol.41 , pp. 1465-1477
    • Parsey, R.V.1    Kegeles, L.S.2    Hwang, D.R.3    Simpson, N.4    Abi-Dargham, A.5    Mawlawi, O.6
  • 16
    • 0035200087 scopus 로고    scopus 로고
    • Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: modeling strategies
    • Ginovart N., Wilson A.A., Meyer J.H., Hussey D., Houle S. Positron emission tomography quantification of [(11)C]-DASB binding to the human serotonin transporter: modeling strategies. J Cereb Blood Flow Metab 2001, 21:1342-1353.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1342-1353
    • Ginovart, N.1    Wilson, A.A.2    Meyer, J.H.3    Hussey, D.4    Houle, S.5
  • 17
    • 0037314599 scopus 로고    scopus 로고
    • Synthesis of N,N-dimethyl-2-(2-amino-4-[18F]fluorophenylthio)benzylamine as a serotonin transporter imaging agent
    • Shiue G.G., Fang P., Shiue C.Y. Synthesis of N,N-dimethyl-2-(2-amino-4-[18F]fluorophenylthio)benzylamine as a serotonin transporter imaging agent. Appl Radiat Isot 2003, 58:183-191.
    • (2003) Appl Radiat Isot , vol.58 , pp. 183-191
    • Shiue, G.G.1    Fang, P.2    Shiue, C.Y.3
  • 18
    • 61649093533 scopus 로고    scopus 로고
    • Validation of 4-[18F]-ADAM as a SERT imaging agent using micro-PET and autoradiography
    • Ma K.H., Huang W.S., Kuo Y.Y., Peng C.J., Liou N.H., Liu R.S., et al. Validation of 4-[18F]-ADAM as a SERT imaging agent using micro-PET and autoradiography. Neuroimage 2009, 45:687-693.
    • (2009) Neuroimage , vol.45 , pp. 687-693
    • Ma, K.H.1    Huang, W.S.2    Kuo, Y.Y.3    Peng, C.J.4    Liou, N.H.5    Liu, R.S.6
  • 19
    • 77949271534 scopus 로고    scopus 로고
    • Biodistribution, toxicity and radiation dosimetry studies of the serotonin transporter radioligand 4-[18F]-ADAM in rats and monkeys
    • Huang Y.Y., Ma K.H., Tseng T.W., Chou T.K., Ng H., Mirsalis J.C., et al. Biodistribution, toxicity and radiation dosimetry studies of the serotonin transporter radioligand 4-[18F]-ADAM in rats and monkeys. Eur J Nucl Med Mol Imaging 2010, 37:545-555.
    • (2010) Eur J Nucl Med Mol Imaging , vol.37 , pp. 545-555
    • Huang, Y.Y.1    Ma, K.H.2    Tseng, T.W.3    Chou, T.K.4    Ng, H.5    Mirsalis, J.C.6
  • 20
    • 64449083090 scopus 로고    scopus 로고
    • An improved synthesis of 4-[18F]-ADAM, a potent serotonin transporter imaging agent
    • Huang Y.Y., Huang W.S., Chu T.C., Shiue C.Y. An improved synthesis of 4-[18F]-ADAM, a potent serotonin transporter imaging agent. Appl Radiat Isot 2009, 67:1063-1067.
    • (2009) Appl Radiat Isot , vol.67 , pp. 1063-1067
    • Huang, Y.Y.1    Huang, W.S.2    Chu, T.C.3    Shiue, C.Y.4
  • 21
    • 0036255441 scopus 로고    scopus 로고
    • Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions
    • Szabo Z., McCann U.D., Wilson A.A., Scheffel U., Owonikoko T., Mathews W.B., et al. Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions. J Nucl Med 2002, 43:678-692.
    • (2002) J Nucl Med , vol.43 , pp. 678-692
    • Szabo, Z.1    McCann, U.D.2    Wilson, A.A.3    Scheffel, U.4    Owonikoko, T.5    Mathews, W.B.6
  • 22
    • 0023902232 scopus 로고
    • Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration
    • Ricaurte G.A., DeLanney L.E., Irwin I., Langston J.W. Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration. Brain Res 1988, 446:165-168.
    • (1988) Brain Res , vol.446 , pp. 165-168
    • Ricaurte, G.A.1    DeLanney, L.E.2    Irwin, I.3    Langston, J.W.4
  • 23
    • 0033564773 scopus 로고    scopus 로고
    • Altered serotonin innervation patterns in the forebrain of monkeys treated with (+/-)3,4-methylenedioxymethamphetamine seven years previously: factors influencing abnormal recovery
    • Hatzidimitriou G., McCann U.D., Ricaurte G.A. Altered serotonin innervation patterns in the forebrain of monkeys treated with (+/-)3,4-methylenedioxymethamphetamine seven years previously: factors influencing abnormal recovery. J Neurosci 1999, 19:5096-5107.
    • (1999) J Neurosci , vol.19 , pp. 5096-5107
    • Hatzidimitriou, G.1    McCann, U.D.2    Ricaurte, G.A.3
  • 24
    • 0033729522 scopus 로고    scopus 로고
    • Graphical analysis of PET data applied to reversible and irreversible tracers
    • Logan J. Graphical analysis of PET data applied to reversible and irreversible tracers. Nucl Med Biol 2000, 27:661-670.
    • (2000) Nucl Med Biol , vol.27 , pp. 661-670
    • Logan, J.1
  • 25
    • 3042776615 scopus 로고    scopus 로고
    • Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain
    • Varnas K., Halldin C., Hall H. Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain. Hum Brain Mapp 2004, 22:246-260.
    • (2004) Hum Brain Mapp , vol.22 , pp. 246-260
    • Varnas, K.1    Halldin, C.2    Hall, H.3
  • 26
    • 77951846157 scopus 로고    scopus 로고
    • Mapping of serotonin transporters by positron emission tomography with [(11)C]DASB in conscious common marmosets: comparison with rhesus monkeys
    • Yokoyama C., Yamanaka H., Onoe K., Kawasaki A., Nagata H., Shirakami K., et al. Mapping of serotonin transporters by positron emission tomography with [(11)C]DASB in conscious common marmosets: comparison with rhesus monkeys. Synapse 2010, 64:594-601.
    • (2010) Synapse , vol.64 , pp. 594-601
    • Yokoyama, C.1    Yamanaka, H.2    Onoe, K.3    Kawasaki, A.4    Nagata, H.5    Shirakami, K.6
  • 27
    • 0344983883 scopus 로고    scopus 로고
    • Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography
    • Laruelle M., Slifstein M., Huang Y. Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography. Mol Imaging Biol 2003, 5:363-375.
    • (2003) Mol Imaging Biol , vol.5 , pp. 363-375
    • Laruelle, M.1    Slifstein, M.2    Huang, Y.3
  • 28
    • 33746257948 scopus 로고    scopus 로고
    • 11C]DASB: test-retest reproducibility using a multilinear reference tissue parametric imaging method
    • 11C]DASB: test-retest reproducibility using a multilinear reference tissue parametric imaging method. J Nucl Med 2006, 47:208-214.
    • (2006) J Nucl Med , vol.47 , pp. 208-214
    • Kim, J.S.1    Ichise, M.2    Sangare, J.3    Innis, R.B.4
  • 29
    • 33845805352 scopus 로고    scopus 로고
    • In vivo quantification of serotonin transporters using [(11)C]DASB and positron emission tomography in humans: modeling considerations
    • Ogden R.T., Ojha A., Erlandsson K., Oquendo M.A., Mann J.J., Parsey R.V. In vivo quantification of serotonin transporters using [(11)C]DASB and positron emission tomography in humans: modeling considerations. J Cereb Blood Flow Metab 2007, 27:205-217.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 205-217
    • Ogden, R.T.1    Ojha, A.2    Erlandsson, K.3    Oquendo, M.A.4    Mann, J.J.5    Parsey, R.V.6
  • 30
    • 0035157572 scopus 로고    scopus 로고
    • Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study
    • Meyer J.H., Wilson A.A., Sagrati S., Hussey D., Carella A., Potter W.Z., et al. Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study. Am J Psychiatry 2001, 158:1843-1849.
    • (2001) Am J Psychiatry , vol.158 , pp. 1843-1849
    • Meyer, J.H.1    Wilson, A.A.2    Sagrati, S.3    Hussey, D.4    Carella, A.5    Potter, W.Z.6
  • 31
    • 34447623791 scopus 로고    scopus 로고
    • Serotonin transporter occupancy of high-dose selective serotonin reuptake inhibitors during major depressive disorder measured with [11C]DASB positron emission tomography
    • Voineskos A.N., Wilson A.A., Boovariwala A., Sagrati S., Houle S., Rusjan P., et al. Serotonin transporter occupancy of high-dose selective serotonin reuptake inhibitors during major depressive disorder measured with [11C]DASB positron emission tomography. Psychopharmacology (Berl) 2007, 193:539-545.
    • (2007) Psychopharmacology (Berl) , vol.193 , pp. 539-545
    • Voineskos, A.N.1    Wilson, A.A.2    Boovariwala, A.3    Sagrati, S.4    Houle, S.5    Rusjan, P.6
  • 32
    • 36849086375 scopus 로고    scopus 로고
    • Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys
    • Banks M.L., Czoty P.W., Gage H.D., Bounds M.C., Garg P.K., Garg S., et al. Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys. Neuropsychopharmacology 2008, 33:219-225.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 219-225
    • Banks, M.L.1    Czoty, P.W.2    Gage, H.D.3    Bounds, M.C.4    Garg, P.K.5    Garg, S.6
  • 33
    • 51849123181 scopus 로고    scopus 로고
    • Positron emission tomographic studies of brain dopamine and serotonin transporters in abstinent (+/-)3,4-methylenedioxymethamphetamine ("ecstasy") users: relationship to cognitive performance
    • McCann U.D., Szabo Z., Vranesic M., Palermo M., Mathews W.B., Ravert H.T., et al. Positron emission tomographic studies of brain dopamine and serotonin transporters in abstinent (+/-)3,4-methylenedioxymethamphetamine ("ecstasy") users: relationship to cognitive performance. Psychopharmacology (Berl) 2008, 200:439-450.
    • (2008) Psychopharmacology (Berl) , vol.200 , pp. 439-450
    • McCann, U.D.1    Szabo, Z.2    Vranesic, M.3    Palermo, M.4    Mathews, W.B.5    Ravert, H.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.