-
1
-
-
79951665862
-
The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders
-
Miller WL, Auchus RJ, (2011) The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders. Endocr Rev 32: 81-151.
-
(2011)
Endocr Rev
, vol.32
, pp. 81-151
-
-
Miller, W.L.1
Auchus, R.J.2
-
2
-
-
62449213811
-
Androgen synthesis in adrenarche
-
Miller WL, (2009) Androgen synthesis in adrenarche. Rev Endocr Metab Disord 10: 3-17.
-
(2009)
Rev Endocr Metab Disord
, vol.10
, pp. 3-17
-
-
Miller, W.L.1
-
3
-
-
77954931135
-
Impact of differential P450c17 phosphorylation by cAMP stimulation and by starvation conditions on enzyme activities and androgen production in NCI-H295R cells
-
Kempna P, Hirsch A, Hofer G, Mullis PE, Fluck CE, (2010) Impact of differential P450c17 phosphorylation by cAMP stimulation and by starvation conditions on enzyme activities and androgen production in NCI-H295R cells. Endocrinology 151: 3686-3696.
-
(2010)
Endocrinology
, vol.151
, pp. 3686-3696
-
-
Kempna, P.1
Hirsch, A.2
Hofer, G.3
Mullis, P.E.4
Fluck, C.E.5
-
4
-
-
0030479422
-
Mechanisms of ACTH(cAMP)-dependent transcription of adrenal steroid hydroxylases
-
Waterman MR, Bischof LJ, (1996) Mechanisms of ACTH(cAMP)-dependent transcription of adrenal steroid hydroxylases. Endocr Res 22: 615-620.
-
(1996)
Endocr Res
, vol.22
, pp. 615-620
-
-
Waterman, M.R.1
Bischof, L.J.2
-
5
-
-
0035542970
-
AMP-activated protein kinase: the energy charge hypothesis revisited
-
Hardie DG, Hawley SA, (2001) AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 23: 1112-1119.
-
(2001)
Bioessays
, vol.23
, pp. 1112-1119
-
-
Hardie, D.G.1
Hawley, S.A.2
-
6
-
-
12144287284
-
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
-
Lizcano JM, Goransson O, Toth R, Deak M, Morrice NA, et al. (2004) LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J 23: 833-843.
-
(2004)
EMBO J
, vol.23
, pp. 833-843
-
-
Lizcano, J.M.1
Goransson, O.2
Toth, R.3
Deak, M.4
Morrice, N.A.5
-
7
-
-
56449117024
-
AMPK: a metabolic gauge regulating whole-body energy homeostasis
-
Lage R, Dieguez C, Vidal-Puig A, Lopez M, (2008) AMPK: a metabolic gauge regulating whole-body energy homeostasis. Trends Mol Med 14: 539-549.
-
(2008)
Trends Mol Med
, vol.14
, pp. 539-549
-
-
Lage, R.1
Dieguez, C.2
Vidal-Puig, A.3
Lopez, M.4
-
8
-
-
0347318052
-
The AMP-activated protein kinase cascade-a unifying system for energy control
-
Carling D, (2004) The AMP-activated protein kinase cascade-a unifying system for energy control. Trends Biochem Sci 29: 18-24.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 18-24
-
-
Carling, D.1
-
9
-
-
0030792297
-
AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location
-
Stapleton D, Woollatt E, Mitchelhill KI, Nicholl JK, Fernandez CS, et al. (1997) AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location. FEBS Lett 409: 452-456.
-
(1997)
FEBS Lett
, vol.409
, pp. 452-456
-
-
Stapleton, D.1
Woollatt, E.2
Mitchelhill, K.I.3
Nicholl, J.K.4
Fernandez, C.S.5
-
10
-
-
13344285343
-
Mammalian AMP-activated protein kinase subfamily
-
Stapleton D, Mitchelhill KI, Gao G, Widmer J, Michell BJ, et al. (1996) Mammalian AMP-activated protein kinase subfamily. J Biol Chem 271: 611-614.
-
(1996)
J Biol Chem
, vol.271
, pp. 611-614
-
-
Stapleton, D.1
Mitchelhill, K.I.2
Gao, G.3
Widmer, J.4
Michell, B.J.5
-
11
-
-
0032524622
-
Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle
-
Thornton C, Snowden MA, Carling D, (1998) Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle. J Biol Chem 273: 12443-12450.
-
(1998)
J Biol Chem
, vol.273
, pp. 12443-12450
-
-
Thornton, C.1
Snowden, M.A.2
Carling, D.3
-
12
-
-
34147152841
-
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
-
Sanders MJ, Grondin PO, Hegarty BD, Snowden MA, Carling D, (2007) Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. Biochem J 403: 139-148.
-
(2007)
Biochem J
, vol.403
, pp. 139-148
-
-
Sanders, M.J.1
Grondin, P.O.2
Hegarty, B.D.3
Snowden, M.A.4
Carling, D.5
-
14
-
-
67749111502
-
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
-
Shackelford DB, Shaw RJ, (2009) The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 9: 563-575.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
15
-
-
1542618348
-
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
-
Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, et al. (2004) The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc Natl Acad Sci U S A 101: 3329-3335.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3329-3335
-
-
Shaw, R.J.1
Kosmatka, M.2
Bardeesy, N.3
Hurley, R.L.4
Witters, L.A.5
-
16
-
-
33746706736
-
AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles
-
Tosca L, Crochet S, Ferre P, Foufelle F, Tesseraud S, et al. (2006) AMP-activated protein kinase activation modulates progesterone secretion in granulosa cells from hen preovulatory follicles. J Endocrinol 190: 85-97.
-
(2006)
J Endocrinol
, vol.190
, pp. 85-97
-
-
Tosca, L.1
Crochet, S.2
Ferre, P.3
Foufelle, F.4
Tesseraud, S.5
-
17
-
-
24944486315
-
Adenosine 5′-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells
-
Tosca L, Froment P, Solnais P, Ferre P, Foufelle F, et al. (2005) Adenosine 5′-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells. Endocrinology 146: 4500-4513.
-
(2005)
Endocrinology
, vol.146
, pp. 4500-4513
-
-
Tosca, L.1
Froment, P.2
Solnais, P.3
Ferre, P.4
Foufelle, F.5
-
18
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
Inoki K, Zhu T, Guan KL, (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115: 577-590.
-
(2003)
Cell
, vol.115
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
19
-
-
0035907330
-
Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3beta -hydroxysteroid dehydrogenase
-
Arlt W, Auchus RJ, Miller WL, (2001) Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3beta-hydroxysteroid dehydrogenase. J Biol Chem 276: 16767-16771.
-
(2001)
J Biol Chem
, vol.276
, pp. 16767-16771
-
-
Arlt, W.1
Auchus, R.J.2
Miller, W.L.3
-
20
-
-
0032488666
-
Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer
-
Auchus RJ, Lee TC, Miller WL, (1998) Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer. J Biol Chem 273: 3158-3165.
-
(1998)
J Biol Chem
, vol.273
, pp. 3158-3165
-
-
Auchus, R.J.1
Lee, T.C.2
Miller, W.L.3
-
21
-
-
0242380351
-
Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells
-
Renner K, Amberger A, Konwalinka G, Kofler R, Gnaiger E, (2003) Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells. Biochim Biophys Acta 1642: 115-123.
-
(2003)
Biochim Biophys Acta
, vol.1642
, pp. 115-123
-
-
Renner, K.1
Amberger, A.2
Konwalinka, G.3
Kofler, R.4
Gnaiger, E.5
-
22
-
-
78651364800
-
Molecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome
-
Schaller A, Hahn D, Jackson CB, Kern I, Chardot C, et al. (2011) Molecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome. BMC Neurol 11: 4.
-
(2011)
BMC Neurol
, vol.11
, pp. 4
-
-
Schaller, A.1
Hahn, D.2
Jackson, C.B.3
Kern, I.4
Chardot, C.5
-
23
-
-
0025074978
-
Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis
-
Gazdar AF, Oie HK, Shackleton CH, Chen TR, Triche TJ, et al. (1990) Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis. Cancer Res 50: 5488-5496.
-
(1990)
Cancer Res
, vol.50
, pp. 5488-5496
-
-
Gazdar, A.F.1
Oie, H.K.2
Shackleton, C.H.3
Chen, T.R.4
Triche, T.J.5
-
24
-
-
38349022275
-
Human adrenal corticocarcinoma NCI-H295R cells produce more androgens than NCI-H295A cells and differ in 3beta-hydroxysteroid dehydrogenase type 2 and 17,20 lyase activities
-
Samandari E, Kempna P, Nuoffer JM, Hofer G, Mullis PE, et al. (2007) Human adrenal corticocarcinoma NCI-H295R cells produce more androgens than NCI-H295A cells and differ in 3beta-hydroxysteroid dehydrogenase type 2 and 17,20 lyase activities. J Endocrinol 195: 459-472.
-
(2007)
J Endocrinol
, vol.195
, pp. 459-472
-
-
Samandari, E.1
Kempna, P.2
Nuoffer, J.M.3
Hofer, G.4
Mullis, P.E.5
-
25
-
-
0942265675
-
Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle
-
Mahlapuu M, Johansson C, Lindgren K, Hjalm G, Barnes BR, et al. (2004) Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle. Am J Physiol Endocrinol Metab 286: E194-200.
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Mahlapuu, M.1
Johansson, C.2
Lindgren, K.3
Hjalm, G.4
Barnes, B.R.5
-
26
-
-
85047689953
-
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?
-
Corton JM, Gillespie JG, Hawley SA, Hardie DG, (1995) 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem 229: 558-565.
-
(1995)
Eur J Biochem
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
27
-
-
0028073143
-
Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase
-
Sullivan JE, Brocklehurst KJ, Marley AE, Carey F, Carling D, et al. (1994) Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS Lett 353: 33-36.
-
(1994)
FEBS Lett
, vol.353
, pp. 33-36
-
-
Sullivan, J.E.1
Brocklehurst, K.J.2
Marley, A.E.3
Carey, F.4
Carling, D.5
-
28
-
-
0033949848
-
Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
-
Winder WW, Holmes BF, Rubink DS, Jensen EB, Chen M, et al. (2000) Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle. J Appl Physiol 88: 2219-2226.
-
(2000)
J Appl Physiol
, vol.88
, pp. 2219-2226
-
-
Winder, W.W.1
Holmes, B.F.2
Rubink, D.S.3
Jensen, E.B.4
Chen, M.5
-
29
-
-
36549014136
-
Compound C inhibits hypoxic activation of HIF-1 independent of AMPK
-
Emerling BM, Viollet B, Tormos KV, Chandel NS, (2007) Compound C inhibits hypoxic activation of HIF-1 independent of AMPK. FEBS Lett 581: 5727-5731.
-
(2007)
FEBS Lett
, vol.581
, pp. 5727-5731
-
-
Emerling, B.M.1
Viollet, B.2
Tormos, K.V.3
Chandel, N.S.4
-
30
-
-
53649106018
-
Compound C inhibits clonal expansion of preadipocytes by increasing p21 level irrespectively of AMPK inhibition
-
Nam M, Lee WH, Bae EJ, Kim SG, (2008) Compound C inhibits clonal expansion of preadipocytes by increasing p21 level irrespectively of AMPK inhibition. Arch Biochem Biophys 479: 74-81.
-
(2008)
Arch Biochem Biophys
, vol.479
, pp. 74-81
-
-
Nam, M.1
Lee, W.H.2
Bae, E.J.3
Kim, S.G.4
-
31
-
-
77958198168
-
AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells
-
Santidrian AF, Gonzalez-Girones DM, Iglesias-Serret D, Coll-Mulet L, Cosialls AM, et al. (2010) AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells. Blood 116: 3023-3032.
-
(2010)
Blood
, vol.116
, pp. 3023-3032
-
-
Santidrian, A.F.1
Gonzalez-Girones, D.M.2
Iglesias-Serret, D.3
Coll-Mulet, L.4
Cosialls, A.M.5
-
32
-
-
44449150712
-
AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase
-
Zang Y, Yu LF, Pang T, Fang LP, Feng X, et al. (2008) AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase. J Biol Chem 283: 6201-6208.
-
(2008)
J Biol Chem
, vol.283
, pp. 6201-6208
-
-
Zang, Y.1
Yu, L.F.2
Pang, T.3
Fang, L.P.4
Feng, X.5
-
33
-
-
0042384482
-
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway
-
Fluck CE, Miller WL, Auchus RJ, (2003) The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway. J Clin Endocrinol Metab 88: 3762-3766.
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3762-3766
-
-
Fluck, C.E.1
Miller, W.L.2
Auchus, R.J.3
-
34
-
-
79955615949
-
Glucocorticoid-induced alterations in mitochondrial membrane properties and respiration in childhood acute lymphoblastic leukemia
-
Eberhart K, Rainer J, Bindreither D, Ritter I, Gnaiger E, et al. (2011) Glucocorticoid-induced alterations in mitochondrial membrane properties and respiration in childhood acute lymphoblastic leukemia. Biochim Biophys Acta 1807: 719-725.
-
(2011)
Biochim Biophys Acta
, vol.1807
, pp. 719-725
-
-
Eberhart, K.1
Rainer, J.2
Bindreither, D.3
Ritter, I.4
Gnaiger, E.5
-
35
-
-
33847234345
-
Effects of metformin on bovine granulosa cells steroidogenesis: possible involvement of adenosine 5′ monophosphate-activated protein kinase (AMPK)
-
Tosca L, Chabrolle C, Uzbekova S, Dupont J, (2007) Effects of metformin on bovine granulosa cells steroidogenesis: possible involvement of adenosine 5′ monophosphate-activated protein kinase (AMPK). Biol Reprod 76: 368-378.
-
(2007)
Biol Reprod
, vol.76
, pp. 368-378
-
-
Tosca, L.1
Chabrolle, C.2
Uzbekova, S.3
Dupont, J.4
-
36
-
-
79955690235
-
Adiponectin (15-36) stimulates steroidogenic acute regulatory (StAR) protein expression and cortisol production in human adrenocortical cells: Role of AMPK and MAPK kinase pathways
-
Ramanjaneya M, Conner AC, Brown JE, Chen J, Digby JE, et al. (2011) Adiponectin (15-36) stimulates steroidogenic acute regulatory (StAR) protein expression and cortisol production in human adrenocortical cells: Role of AMPK and MAPK kinase pathways. Biochim Biophys Acta 1813: 802-809.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 802-809
-
-
Ramanjaneya, M.1
Conner, A.C.2
Brown, J.E.3
Chen, J.4
Digby, J.E.5
|