Glucocorticoid-induced alterations in mitochondrial membrane properties and respiration in childhood acute lymphoblastic leukemia

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1807, Issue 6, 2011, Pages 719-725

  Eberhart, Karin ^a,c   Rainer, Johannes ^b,c   Bindreither, Daniel ^b   Ritter, Ireen ^a   Gnaiger, Erich ^d   Kofler, Reinhard ^b,c   Oefner, Peter J ^a   Renner, Kathrin ^a,e  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c TYROLEAN CANCER RESEARCH INSTITUTE   (Austria)

^d Department of Visceral Transplant and Thoracic Surgery   (Austria)

^e NONE   (Germany)

Author keywords

Acute lymphoblastic leukemia; Apoptosis; Glucocorticoid; Mitochondrial membrane properties; Mitochondrial respiration; Mitochondrial transport

Indexed keywords

DEXAMETHASONE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CELL; CELL FRACTIONATION; CELL MEMBRANE; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LYMPHOBLAST; MEMBRANE TRANSPORT; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; RESPIROMETRY; TREATMENT OUTCOME;

ANTINEOPLASTIC AGENTS, HORMONAL; CELL LINE, TUMOR; CELL RESPIRATION; DEXAMETHASONE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; GLUCOCORTICOIDS; HUMANS; MICROARRAY ANALYSIS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; OXYGEN CONSUMPTION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA;

EID: 79955615949     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2010.12.010     Document Type: Article

References (32)

1. F. Palmieri The mitochondrial transporter family (SLC25): physiological and pathological implications Pflügers Arch. Eur. J. Physiol. 447 2004 689 709 (Pubitemid 38241455)
2. E.R. Kunji The role and structure of mitochondrial carriers FEBS Lett. 564 2004 239 244 (Pubitemid 38520927)
3. S. Sugiyama, S. Moritoh, Y. Furukawa, T. Mizuno, Y.M. Lim, L. Tsuda, and Y. Nishida Involvement of the mitochondrial protein translocator component Tim50 in growth, cell proliferation and the modulation of respiration in drosophila Genetics 176 2007 927 936 (Pubitemid 46961096)
4. N. Joza, S.A. Susin, E. Daugas, W.L. Stanford, S.K. Cho, C.Y. Li, T. Sasaki, A.J. Elia, H.Y. Cheng, L. Ravagnan, K.F. Ferri, N. Zamzami, A. Wakeham, R. Hakem, H. Yoshida, Y.Y. Kong, T.W. Mak, J.C. Zuniga-Pflucker, G. Kroemer, and J.M. Penninger Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death Nature 410 2001 549 554 (Pubitemid 32267191)
5. L. Scorrano, and S.J. Korsmeyer Mechanisms of cytochrome c release by proapoptotic BCL-2 family members Biochem. Biophys. Res. Commun. 304 2003 437 444 (Pubitemid 36506515)
6. M. Dordelmann, A. Reiter, A. Borkhardt, W.D. Ludwig, N. Gotz, S. Viehmann, H. Gadner, H. Riehm, and M. Schrappe Prednisone response is the strongest predictor of treatment outcome in infant acute lymphoblastic leukemia Blood 94 1999 1209 1217 (Pubitemid 29380401)
7. C.H. Pui, and W.E. Evans Treatment of acute lymphoblastic leukemia N. Engl. J. Med. 354 2006 166 178 (Pubitemid 43076714)
8. R. Kofler The molecular basis of glucocorticoid-induced apoptosis of lymphoblastic leukemia cells Histochem. Cell Biol. 114 2000 1 7 (Pubitemid 30609850)
9. K. Eberhart, K. Renner, I. Ritter, M. Kastenberger, K. Singer, C. Hellerbrand, M. Kreutz, R. Kofler, and P.J. Oefner Low doses of 2-deoxy-glucose sensitize acute lymphoblastic leukemia cells to glucocorticoid-induced apoptosis Leukemia 23 2009 2167 2170
10. M.E. Tome, D.B. Johnson, B.K. Samulitis, R.T. Dorr, and M.M. Briehl Glucose 6-phosphate dehydrogenase overexpression models glucose deprivation and sensitizes lymphoma cells to apoptosis Antioxid. Redox Signal. 8 2006 1315 1327 (Pubitemid 44182430)
11. A.H. Beesley, M.J. Firth, J. Ford, R.E. Weller, J.R. Freitas, K.U. Perera, and U.R. Kees Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism Br. J. Cancer 100 2009 1926 1936
12. E.M. Strasser-Wozak, R. Hattmannstorfer, M. Hala, B.L. Hartmann, M. Fiegl, S. Geley, and R. Kofler Splice site mutation in the glucocorticoid receptor gene causes resistance to glucocorticoid-induced apoptosis in a human acute leukemic cell line Cancer Res. 55 1995 348 353
13. H.W. Findley Jr., M.D. Cooper, T.H. Kim, C. Alvarado, and A.H. Ragab Two new acute lymphoblastic leukemia cell lines with early B-cell phenotypes Blood 60 1982 1305 1309 (Pubitemid 13211367)
14. S. Schmidt, J.A. Irving, L. Minto, E. Matheson, L. Nicholson, A. Ploner, W. Parson, A. Kofler, M. Amort, M. Erdel, A. Hall, and R. Kofler Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor FASEB J. 20 2006 2600 2602
15. M. Zhou, L. Gu, F. Li, Y. Zhu, W.G. Woods, and H.W. Findley DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells J. Pharmacol. Exp. Ther. 303 2002 124 131
16. I. Nicoletti, G. Migliorati, M.C. Pagliacci, F. Grignani, and C. Riccardi A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry J. Immunol. Meth. 139 1991 271 279
17. S. Stadlmann, K. Renner, J. Pollheimer, P.L. Moser, A.G. Zeimet, F.A. Offner, and E. Gnaiger Preserved coupling of oxidative phosphorylation but decreased mitochondrial respiratory capacity in IL-1beta-treated human peritoneal mesothelial cells Cell Biochem. Biophys. 44 2006 179 186 (Pubitemid 43172316)
18. E. Gnaiger Capacity of oxidative phosphorylation in human skeletal muscle: new perspectives of mitochondrial physiology Int. J. Biochem. Cell Biol. 41 2009 1837 1845
19. A.V. Kuznetsov, S. Schneeberger, R. Seiler, G. Brandacher, W. Mark, W. Steurer, V. Saks, Y. Usson, R. Margreiter, and E. Gnaiger Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion Am. J. Physiol. Heart Circ. Physiol. 286 2004 H1633 H1641
20. D. Pesta, and E. Gnaiger High-resolution respirometry. OXPHOS protocols for human cell cultures and permeabilized fibres from small biopsies of human muscle C. Palmeira, A. Moreno, Mitochondrial Bioenergetics: Methods and Protocols 2010
21. J. Rainer, C. Ploner, S. Jesacher, A. Ploner, M. Eduardoff, M. Mansha, M. Wasim, R. Panzer-Grumayer, Z. Trajanoski, H. Niederegger, and R. Kofler Glucocorticoid-regulated microRNAs and mirtrons in acute lymphoblastic leukemia Leukemia 23 2009 746 752
22. Z. Wu, R.A. Irizarry, R. Gentleman, F. Martinez-Murillo, and F. Spencer A model-based background adjustment for oligonucleotide expression arrays J. Am. Stat. Assoc. 99 2004 909 918
23. G. Smyth Linear models and empirical Bayes methods for assessing differential expression in microarray experiments Stat. Appl. Genet. Mol. Biol. 3 2004 29
24. Y. Benjamini, and Y. Hochberg Controlling the false discovery rate: a practical and powerful approach to multiple testing J. R. Statist. Soc. B 57 1995 289 300
25. S. Schmidt, J. Rainer, S. Riml, C. Ploner, S. Jesacher, C. Achmuller, E. Presul, S. Skvortsov, R. Crazzolara, M. Fiegl, T. Raivio, O.A. Janne, S. Geley, B. Meister, and R. Kofler Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia Blood 107 2006 2061 2069 (Pubitemid 43292367)
26. E. Hulleman, K.M. Kazemier, A. Holleman, D.J. VanderWeele, C.M. Rudin, M.J. Broekhuis, W.E. Evans, R. Pieters, and M.L. den Boer Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells Blood 113 2009 2014 2021
27. M.E. Tome, N.W. Lutz, and M.M. Briehl Overexpression of catalase or Bcl-2 delays or prevents alterations in phospholipid metabolism during glucocorticoid-induced apoptosis in WEHI7.2 cells Biochim. Biophys. Acta 1642 2003 149 162 (Pubitemid 37315658)
28. M.E. Tome, N.W. Lutz, and M.M. Briehl Overexpression of catalase or Bcl-2 alters glucose and energy metabolism concomitant with dexamethasone resistance Biochim. Biophys. Acta 1693 2004 57 72 (Pubitemid 38970136)
29. M.J. Lindhurst, G. Fiermonte, S. Song, E. Struys, F. De Leonardis, P.L. Schwartzberg, A. Chen, A. Castegna, N. Verhoeven, C.K. Mathews, F. Palmieri, and L.G. Biesecker Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia Proc. Natl Acad. Sci. USA 103 2006 15927 15932 (Pubitemid 44657569)
30. F. Palmieri Diseases caused by defects of mitochondrial carriers: a review Biochim. Biophys. Acta 1777 2008 564 578
31. D. Mokranjac, and W. Neupert Protein import into mitochondria Biochem. Soc. Trans. 33 2005 1019 1023 (Pubitemid 41659104)
32. J.M. Garland, and A. Halestrap Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest J Biol. Chem. 272 1997 4680 4688 (Pubitemid 27090009)