-
1
-
-
80053209157
-
Multicenter study of subcutaneous alemtuzumab administered at reduced dose in patients with fludarabine-relapsed/refractory chronic lymphocytic leukemia: final analysis
-
Bezares, R.F., Stemelin, G., Diaz, A., Argentieri, D., Zubiaur, E.L., Garay, G., Bartomioli, M., Ryser, R. & Milone, G. (2011) Multicenter study of subcutaneous alemtuzumab administered at reduced dose in patients with fludarabine-relapsed/refractory chronic lymphocytic leukemia: final analysis. Leukaemia & Lymphoma, 52, 1936-1941.
-
(2011)
Leukaemia & Lymphoma
, vol.52
, pp. 1936-1941
-
-
Bezares, R.F.1
Stemelin, G.2
Diaz, A.3
Argentieri, D.4
Zubiaur, E.L.5
Garay, G.6
Bartomioli, M.7
Ryser, R.8
Milone, G.9
-
2
-
-
0029981025
-
National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment
-
Cheson, B.D., Bennett, J.M., Grever, M., Kay, N., Keating, M.J., O'Brien, S. & Rai, K.R. (1996) National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood, 87, 4990-4997.
-
(1996)
Blood
, vol.87
, pp. 4990-4997
-
-
Cheson, B.D.1
Bennett, J.M.2
Grever, M.3
Kay, N.4
Keating, M.J.5
O'Brien, S.6
Rai, K.R.7
-
3
-
-
15244362778
-
A pilot study of low-dose subcutaneous alemtuzumab therapy for patients with chemotherapy-refractory chronic lymphocytic leukemia
-
Cortelezzi, A., Pasquini, M.C., Sarina, B., Bertani, G., Grifoni, F., Colombi, M. & Lambertenghi Deliliers, G. (2005) A pilot study of low-dose subcutaneous alemtuzumab therapy for patients with chemotherapy-refractory chronic lymphocytic leukemia. Haematologica, 90, 410-412.
-
(2005)
Haematologica
, vol.90
, pp. 410-412
-
-
Cortelezzi, A.1
Pasquini, M.C.2
Sarina, B.3
Bertani, G.4
Grifoni, F.5
Colombi, M.6
Lambertenghi Deliliers, G.7
-
4
-
-
70450267533
-
Low-dose subcutaneous alemtuzumab in refractory chronic lymphocytic leukaemia (CLL): results of a prospective, single-arm multicentre study
-
Cortelezzi, A., Pasquini, M.C., Gardellini, A., Gianelli, U., Bossi, A., Reda, G., Sarina, B., Musto, P., Barcellini, W., Neri, A. & Deliliers, G.L. (2009) Low-dose subcutaneous alemtuzumab in refractory chronic lymphocytic leukaemia (CLL): results of a prospective, single-arm multicentre study. Leukemia, 23, 2027-2033.
-
(2009)
Leukemia
, vol.23
, pp. 2027-2033
-
-
Cortelezzi, A.1
Pasquini, M.C.2
Gardellini, A.3
Gianelli, U.4
Bossi, A.5
Reda, G.6
Sarina, B.7
Musto, P.8
Barcellini, W.9
Neri, A.10
Deliliers, G.L.11
-
5
-
-
79953710007
-
An observational study of outcomes after initial infused therapy in Medicare patients diagnosed with chronic lymphocytic leukemia
-
Danese, M.D., Griffiths, R.I., Gleeson, M., Satram-Hoang, S., Knopf, K., Mikhael, J. & Reyes, C. (2011) An observational study of outcomes after initial infused therapy in Medicare patients diagnosed with chronic lymphocytic leukemia. Blood, 117, 3505-3513.
-
(2011)
Blood
, vol.117
, pp. 3505-3513
-
-
Danese, M.D.1
Griffiths, R.I.2
Gleeson, M.3
Satram-Hoang, S.4
Knopf, K.5
Mikhael, J.6
Reyes, C.7
-
6
-
-
33751009390
-
Routine clinical use of alemtuzumab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: a nation-wide retrospective study in Austria
-
Fiegl, M., Falkner, A., Hopfinger, G., Brugger, S., Zabernigg, A., Bauer, F., Haslbauer, F., Demirtas, D., Grossschmidt, P., Tatzreiter, G., Gastl, G. & Greil, R. (2006) Routine clinical use of alemtuzumab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: a nation-wide retrospective study in Austria. Cancer, 107, 2408-2416.
-
(2006)
Cancer
, vol.107
, pp. 2408-2416
-
-
Fiegl, M.1
Falkner, A.2
Hopfinger, G.3
Brugger, S.4
Zabernigg, A.5
Bauer, F.6
Haslbauer, F.7
Demirtas, D.8
Grossschmidt, P.9
Tatzreiter, G.10
Gastl, G.11
Greil, R.12
-
7
-
-
78649471912
-
Clinical outcome of pretreated B-cell chronic lymphocytic leukemia following alemtuzumab therapy: a retrospective study on various cytogenetic risk categories
-
Fiegl, M., Erdel, M., Tinhofer, I., Brychtova, Y., Panovska, A., Doubek, M., Eigenberger, K., Fonatsch, C., Hopfinger, G., Muhlberger, H., Zabernigg, A., Falkner, F., Gastl, G., Mayer, J. & Greil, R. (2010) Clinical outcome of pretreated B-cell chronic lymphocytic leukemia following alemtuzumab therapy: a retrospective study on various cytogenetic risk categories. Annals of Oncology, 21, 2410-2419.
-
(2010)
Annals of Oncology
, vol.21
, pp. 2410-2419
-
-
Fiegl, M.1
Erdel, M.2
Tinhofer, I.3
Brychtova, Y.4
Panovska, A.5
Doubek, M.6
Eigenberger, K.7
Fonatsch, C.8
Hopfinger, G.9
Muhlberger, H.10
Zabernigg, A.11
Falkner, F.12
Gastl, G.13
Mayer, J.14
Greil, R.15
-
8
-
-
77956655704
-
Chronic lymphocytic leukemia: planning for an aging population
-
Gribben, J.G. (2010) Chronic lymphocytic leukemia: planning for an aging population. Expert Review of Anticancer Therapy, 10, 1389-1394.
-
(2010)
Expert Review of Anticancer Therapy
, vol.10
, pp. 1389-1394
-
-
Gribben, J.G.1
-
9
-
-
60649093569
-
Rediscovering alemtuzumab: current and emerging therapeutic roles
-
Gribben, J.G. & Hallek, M. (2009) Rediscovering alemtuzumab: current and emerging therapeutic roles. British Journal Haematology, 144, 818-831.
-
(2009)
British Journal Haematology
, vol.144
, pp. 818-831
-
-
Gribben, J.G.1
Hallek, M.2
-
10
-
-
84856267399
-
Low dose alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia patients
-
in press (doi:).
-
Gritti, G., Reda, G., Maura, F., Piciocchi, A., Baldini, L., Molica, S., Neri, A. & Cortelezzi, A. (2011) Low dose alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia patients. Leukaemia & Lymphoma, in press (doi:).
-
(2011)
Leukaemia & Lymphoma
-
-
Gritti, G.1
Reda, G.2
Maura, F.3
Piciocchi, A.4
Baldini, L.5
Molica, S.6
Neri, A.7
Cortelezzi, A.8
-
11
-
-
78650007259
-
State of the art treatment of chronic lymphocytic leukaemia
-
Hallek, M. & Pflug, N. (2011) State of the art treatment of chronic lymphocytic leukaemia. Blood Reviews, 25, 1-9.
-
(2011)
Blood Reviews
, vol.25
, pp. 1-9
-
-
Hallek, M.1
Pflug, N.2
-
12
-
-
37649004407
-
Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia
-
Hillmen, P., Skotnicki, A.B., Robak, T., Jaksic, B., Dmoszynska, A., Wu, J., Sirard, C. & Mayer, J. (2007) Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia. Journal of Clinical Oncology, 25, 5616-5623.
-
(2007)
Journal of Clinical Oncology
, vol.25
, pp. 5616-5623
-
-
Hillmen, P.1
Skotnicki, A.B.2
Robak, T.3
Jaksic, B.4
Dmoszynska, A.5
Wu, J.6
Sirard, C.7
Mayer, J.8
-
13
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study
-
Keating, M.J., Flinn, I., Jain, V., Binet, J.L., Hillmen, P., Byrd, J., Albitar, M., Brettman, L., Santabarbara, P., Wacker, B. & Rai, K.R. (2002) Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study. Blood, 99, 3554-3561.
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
Binet, J.L.4
Hillmen, P.5
Byrd, J.6
Albitar, M.7
Brettman, L.8
Santabarbara, P.9
Wacker, B.10
Rai, K.R.11
-
14
-
-
11144357712
-
Management guidelines for use of alemtuzumab in B-cell chronic lymphocytic leukemia
-
Keating, M., Coutre, S., Rai, K., Osterborg, A., Faderl, S., Kennedy, B., Kipps, T., Bodey, G., Byrd, J.C., Rosen, S., Dearden, C., Dyer, M.J. & Hillmen, P. (2004) Management guidelines for use of alemtuzumab in B-cell chronic lymphocytic leukemia. Clin Lymphoma, 4, 220-227.
-
(2004)
Clin Lymphoma
, vol.4
, pp. 220-227
-
-
Keating, M.1
Coutre, S.2
Rai, K.3
Osterborg, A.4
Faderl, S.5
Kennedy, B.6
Kipps, T.7
Bodey, G.8
Byrd, J.C.9
Rosen, S.10
Dearden, C.11
Dyer, M.J.12
Hillmen, P.13
-
15
-
-
24944566741
-
Low-dose intravenous alemtuzumab therapy in pretreated patients affected by chronic lymphocytic leukemia. A single center experience
-
Laurenti, L., Piccioni, P., Tarnani, M., Efremov, D.G., Fiorini, A., Garzia, M. & Sica, S. (2005) Low-dose intravenous alemtuzumab therapy in pretreated patients affected by chronic lymphocytic leukemia. A single center experience. Haematologica, 90, 1143-1145.
-
(2005)
Haematologica
, vol.90
, pp. 1143-1145
-
-
Laurenti, L.1
Piccioni, P.2
Tarnani, M.3
Efremov, D.G.4
Fiorini, A.5
Garzia, M.6
Sica, S.7
-
16
-
-
11144357657
-
Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
-
Lozanski, G., Heerema, N.A., Flinn, I.W., Smith, L., Harbison, J., Webb, J., Moran, M., Lucas, M., Lin, T., Hackbarth, M.L., Proffitt, J.H., Lucas, D., Grever, M.R. & Byrd, J.C. (2004) Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood, 103, 3278-3281.
-
(2004)
Blood
, vol.103
, pp. 3278-3281
-
-
Lozanski, G.1
Heerema, N.A.2
Flinn, I.W.3
Smith, L.4
Harbison, J.5
Webb, J.6
Moran, M.7
Lucas, M.8
Lin, T.9
Hackbarth, M.L.10
Proffitt, J.H.11
Lucas, D.12
Grever, M.R.13
Byrd, J.C.14
-
17
-
-
0036683449
-
Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
-
Lundin, J., Kimby, E., Bjorkholm, M., Broliden, P.A., Celsing, F., Hjalmar, V., Mollgard, L., Rebello, P., Hale, G., Waldmann, H., Mellstedt, H. & Osterborg, A. (2002) Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood, 100, 768-773.
-
(2002)
Blood
, vol.100
, pp. 768-773
-
-
Lundin, J.1
Kimby, E.2
Bjorkholm, M.3
Broliden, P.A.4
Celsing, F.5
Hjalmar, V.6
Mollgard, L.7
Rebello, P.8
Hale, G.9
Waldmann, H.10
Mellstedt, H.11
Osterborg, A.12
-
18
-
-
77956632397
-
Infectious complications of chronic lymphocytic leukaemia: pathogenesis, spectrum of infection, preventive approaches
-
Morrison, V.A. (2010) Infectious complications of chronic lymphocytic leukaemia: pathogenesis, spectrum of infection, preventive approaches. Best Pract Res Clin Haematol, 23, 145-153.
-
(2010)
Best Pract Res Clin Haematol
, vol.23
, pp. 145-153
-
-
Morrison, V.A.1
-
19
-
-
10444276466
-
Infectious toxicity using alemtuzumab
-
Nosari, A., Montillo, M. & Morra, E. (2004) Infectious toxicity using alemtuzumab. Haematologica, 89, 1415-1419.
-
(2004)
Haematologica
, vol.89
, pp. 1415-1419
-
-
Nosari, A.1
Montillo, M.2
Morra, E.3
-
20
-
-
40849100404
-
Characteristics and stage of the underlying diseases could determine the risk of opportunistic infections in patients receiving alemtuzumab
-
Nosari, A., Tedeschi, A., Ricci, F. & Montillo, M. (2008) Characteristics and stage of the underlying diseases could determine the risk of opportunistic infections in patients receiving alemtuzumab. Haematologica, 93, e30-e31.
-
(2008)
Haematologica
, vol.93
-
-
Nosari, A.1
Tedeschi, A.2
Ricci, F.3
Montillo, M.4
-
21
-
-
0029937765
-
Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukaemia
-
Osterborg, A., Fassas, A.S., Anagnostopoulos, A., Dyer, M.J., Catovsky, D. & Mellstedt, H. (1996) Humanized CD52 monoclonal antibody Campath-1H as first-line treatment in chronic lymphocytic leukaemia. British Journal Haematology, 93, 151-153.
-
(1996)
British Journal Haematology
, vol.93
, pp. 151-153
-
-
Osterborg, A.1
Fassas, A.S.2
Anagnostopoulos, A.3
Dyer, M.J.4
Catovsky, D.5
Mellstedt, H.6
-
22
-
-
0030897222
-
Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia
-
Osterborg, A., Dyer, M.J., Bunjes, D., Pangalis, G.A., Bastion, Y., Catovsky, D. & Mellstedt, H. (1997) Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia. Journal of Clinical Oncology, 15, 1567-1574.
-
(1997)
Journal of Clinical Oncology
, vol.15
, pp. 1567-1574
-
-
Osterborg, A.1
Dyer, M.J.2
Bunjes, D.3
Pangalis, G.A.4
Bastion, Y.5
Catovsky, D.6
Mellstedt, H.7
-
23
-
-
70450265546
-
Management guidelines for the use of alemtuzumab in chronic lymphocytic leukemia
-
Osterborg, A., Foa, R., Bezares, R.F., Dearden, C., Dyer, M.J., Geisler, C., Lin, T.S., Montillo, M., van Oers, M.H., Wendtner, C.M. & Rai, K.R. (2009) Management guidelines for the use of alemtuzumab in chronic lymphocytic leukemia. Leukemia, 23, 1980-1988.
-
(2009)
Leukemia
, vol.23
, pp. 1980-1988
-
-
Osterborg, A.1
Foa, R.2
Bezares, R.F.3
Dearden, C.4
Dyer, M.J.5
Geisler, C.6
Lin, T.S.7
Montillo, M.8
van Oers, M.H.9
Wendtner, C.M.10
Rai, K.R.11
-
24
-
-
20944449901
-
Prevalence and etiology of altered liver tests: a population-based survey in a Mediterranean town
-
Pendino, G.M., Mariano, A., Surace, P., Caserta, C.A., Fiorillo, M.T., Amante, A., Bruno, S., Mangano, C., Polito, I., Amato, F., Cotichini, R., Stroffolini, T. & Mele, A. (2005) Prevalence and etiology of altered liver tests: a population-based survey in a Mediterranean town. Hepatology, 41, 1151-1159.
-
(2005)
Hepatology
, vol.41
, pp. 1151-1159
-
-
Pendino, G.M.1
Mariano, A.2
Surace, P.3
Caserta, C.A.4
Fiorillo, M.T.5
Amante, A.6
Bruno, S.7
Mangano, C.8
Polito, I.9
Amato, F.10
Cotichini, R.11
Stroffolini, T.12
Mele, A.13
-
25
-
-
33746137366
-
Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects
-
Pettitt, A.R., Matutes, E. & Oscier, D. (2006) Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects. Leukemia, 20, 1441-1445.
-
(2006)
Leukemia
, vol.20
, pp. 1441-1445
-
-
Pettitt, A.R.1
Matutes, E.2
Oscier, D.3
-
26
-
-
70149113077
-
-
R Development Core Team. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, URL
-
R Development Core Team (2009). R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. ISBN 3-900051-07-0, URL http://www.R-project.org.
-
(2009)
R: A language and environment for statistical computing
-
-
-
27
-
-
0037106502
-
Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine
-
Rai, K.R., Freter, C.E., Mercier, R.J., Cooper, M.R., Mitchell, B.S., Stadtmauer, E.A., Santabarbara, P., Wacker, B. & Brettman, L. (2002) Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine. Journal of Clinical Oncology, 20, 3891-3897.
-
(2002)
Journal of Clinical Oncology
, vol.20
, pp. 3891-3897
-
-
Rai, K.R.1
Freter, C.E.2
Mercier, R.J.3
Cooper, M.R.4
Mitchell, B.S.5
Stadtmauer, E.A.6
Santabarbara, P.7
Wacker, B.8
Brettman, L.9
-
28
-
-
0037043653
-
Campath-1H-induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy
-
Stilgenbauer, S. & Dohner, H. (2002) Campath-1H-induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy. New England Journal of Medicine, 347, 452-453.
-
(2002)
New England Journal of Medicine
, vol.347
, pp. 452-453
-
-
Stilgenbauer, S.1
Dohner, H.2
-
29
-
-
69849107362
-
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group
-
Stilgenbauer, S., Zenz, T., Winkler, D., Buhler, A., Schlenk, R.F., Groner, S., Busch, R., Hensel, M., Duhrsen, U., Finke, J., Dreger, P., Jager, U., Lengfelder, E., Hohloch, K., Soling, U., Schlag, R., Kneba, M., Hallek, M. & Dohner, H. (2009) Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group. Journal of Clinical Oncology, 27, 3994-4001.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 3994-4001
-
-
Stilgenbauer, S.1
Zenz, T.2
Winkler, D.3
Buhler, A.4
Schlenk, R.F.5
Groner, S.6
Busch, R.7
Hensel, M.8
Duhrsen, U.9
Finke, J.10
Dreger, P.11
Jager, U.12
Lengfelder, E.13
Hohloch, K.14
Soling, U.15
Schlag, R.16
Kneba, M.17
Hallek, M.18
Dohner, H.19
-
30
-
-
70350511471
-
Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
-
Zenz, T., Habe, S., Denzel, T., Mohr, J., Winkler, D., Buhler, A., Sarno, A., Groner, S., Mertens, D., Busch, R., Hallek, M., Dohner, H. & Stilgenbauer, S. (2009) Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial. Blood, 114, 2589-2597.
-
(2009)
Blood
, vol.114
, pp. 2589-2597
-
-
Zenz, T.1
Habe, S.2
Denzel, T.3
Mohr, J.4
Winkler, D.5
Buhler, A.6
Sarno, A.7
Groner, S.8
Mertens, D.9
Busch, R.10
Hallek, M.11
Dohner, H.12
Stilgenbauer, S.13
|