-
1
-
-
34548138938
-
The role of prognostic factors in assessing 'high-risk' subgroups of patients with chronic lymphocytic leukemia
-
Kay NE, O'Brien SM, Pettitt AR et al. The role of prognostic factors in assessing 'high-risk' subgroups of patients with chronic lymphocytic leukemia. Leukemia 2007; 21: 1885-1891.
-
(2007)
Leukemia
, vol.21
, pp. 1885-1891
-
-
Kay, N.E.1
O'Brien, S.M.2
Pettitt, A.R.3
-
2
-
-
0034727833
-
Genomic aberrations and survival in chronic lymphocytic leukemia
-
Dö hner H, Stilgenbauer S, Benner A et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000; 343: 1910-1916.
-
(2000)
N Engl J Med
, vol.343
, pp. 1910-1916
-
-
Dö hner, H.1
Stilgenbauer, S.2
Benner, A.3
-
3
-
-
0034765991
-
The CD52 antigen and development of the CAMPATH antibodies
-
Hale G. The CD52 antigen and development of the CAMPATH antibodies. Cytotherapy 2001; 3: 137-143.
-
(2001)
Cytotherapy
, vol.3
, pp. 137-143
-
-
Hale, G.1
-
4
-
-
0023911111
-
Reshaping human antibodies for therapy
-
Riechmann L, Clark M, Waldmann H et al. Reshaping human antibodies for therapy. Nature 1988; 332: 323-327.
-
(1988)
Nature
, vol.332
, pp. 323-327
-
-
Riechmann, L.1
Clark, M.2
Waldmann, H.3
-
5
-
-
0037092951
-
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study
-
Keating MJ, Flinn I, Jain V et al. Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international study. Blood 2002; 99: 3554-3561.
-
(2002)
Blood
, vol.99
, pp. 3554-3561
-
-
Keating, M.J.1
Flinn, I.2
Jain, V.3
-
6
-
-
21144456107
-
Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival
-
Moreton P, Kennedy B, Lucas G et al. Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival. J Clin Oncol 2005; 23: 2971-2979.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2971-2979
-
-
Moreton, P.1
Kennedy, B.2
Lucas, G.3
-
7
-
-
0030897222
-
Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia
-
Osterborg A, Dyer MJ, Bunjes D et al. Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia. J Clin Oncol 1997; 15: 1567-1574.
-
(1997)
J Clin Oncol
, vol.15
, pp. 1567-1574
-
-
Osterborg, A.1
Dyer, M.J.2
Bunjes, D.3
-
8
-
-
0038315030
-
Patients with refractory B-CLL and T-PLL treated with alemtuzumab (Campath) on a compassionate basis. A report on efficacy and safety of CAM511 trial
-
(Abstr 3165)
-
Rai K, Keating MJ, Coutre S et al. Patients with refractory B-CLL and T-PLL treated with alemtuzumab (Campath) on a compassionate basis. A report on efficacy and safety of CAM511 trial. Blood 2002: 100: 802a (Abstr 3165).
-
(2002)
Blood
, vol.100
-
-
Rai, K.1
Keating, M.J.2
Coutre, S.3
-
9
-
-
0037106502
-
Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine
-
Rai KR, Freter CE, Mercier RJ et al. Alemtuzumab in previously treated chronic lymphocytic leukemia patients who also had received fludarabine. J Clin Oncol 2002; 20: 3891-3897.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3891-3897
-
-
Rai, K.R.1
Freter, C.E.2
Mercier, R.J.3
-
10
-
-
55549092587
-
Final report of the UKCLL02 Trial: a phase II study of subcutaneous alemtuzumab plus fludarabine in patients with fludarabine refractory CLL
-
(Abstr 34[0])
-
Sayala HM, Moreton P, Jones RA et al. Final report of the UKCLL02 Trial: a phase II study of subcutaneous alemtuzumab plus fludarabine in patients with fludarabine refractory CLL. Blood 2006: 108: 14a (Abstr 34[0]).
-
(2006)
Blood
, vol.108
-
-
Sayala, H.M.1
Moreton, P.2
Jones, R.A.3
-
11
-
-
0042071567
-
Phase II study of alemtuzumab in chronic lymphoproliferative disorders
-
Ferrajoli A, O'Brien SM, Cortes JE et al. Phase II study of alemtuzumab in chronic lymphoproliferative disorders. Cancer 2003; 98: 773-778.
-
(2003)
Cancer
, vol.98
, pp. 773-778
-
-
Ferrajoli, A.1
O'Brien, S.M.2
Cortes, J.E.3
-
12
-
-
0036683449
-
Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
-
Lundin J, Kimby E, Bjorkholm M et al. Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood 2002; 100: 768-773.
-
(2002)
Blood
, vol.100
, pp. 768-773
-
-
Lundin, J.1
Kimby, E.2
Bjorkholm, M.3
-
13
-
-
37649004407
-
Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia
-
Hillmen P, Skotnicki AB, Robak T et al. Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia. J Clin Oncol 2007; 25: 5616-5623.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5616-5623
-
-
Hillmen, P.1
Skotnicki, A.B.2
Robak, T.3
-
14
-
-
33751009390
-
Austrian Collaborative Study Group on Alemtuzumab in Chronic Lymphocytic Leukemia. Routine clinical use of alemtuzumab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: a nation-wide retrospective study in Austria
-
Fiegl M, Falkner A, Hopfinger G et al. Austrian Collaborative Study Group on Alemtuzumab in Chronic Lymphocytic Leukemia. Routine clinical use of alemtuzumab in patients with heavily pretreated B-cell chronic lymphocytic leukemia: a nation-wide retrospective study in Austria. Cancer 2006; 107: 2408-2416.
-
(2006)
Cancer
, vol.107
, pp. 2408-2416
-
-
Fiegl, M.1
Falkner, A.2
Hopfinger, G.3
-
15
-
-
11144357657
-
Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
-
Lozanski G, Heerema NA, Flinn IW et al. Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood 2004; 103: 3278-3281.
-
(2004)
Blood
, vol.103
, pp. 3278-3281
-
-
Lozanski, G.1
Heerema, N.A.2
Flinn, I.W.3
-
16
-
-
69849107362
-
Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group
-
Stilgenbauer S, Zenz T, Winkler D et al. Subcutaneous alemtuzumab in fludarabine-refractory chronic lymphocytic leukemia: clinical results and prognostic marker analyses from the CLL2H study of the German Chronic Lymphocytic Leukemia Study Group. J Clin Oncol 2009; 27: 3994-4001.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3994-4001
-
-
Stilgenbauer, S.1
Zenz, T.2
Winkler, D.3
-
17
-
-
33746137366
-
Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects
-
Pettit AR, Matutes E, Oscier D. Alemtuzumab in combination with high-dose methylprednisolone is a logical, feasible and highly active therapeutic regimen in chronic lymphocytic leukaemia patients with p53 defects. Leukemia 2006; 20: 1441-1445.
-
(2006)
Leukemia
, vol.20
, pp. 1441-1445
-
-
Pettit, A.R.1
Matutes, E.2
Oscier, D.3
-
18
-
-
27144437196
-
The efficacy of alemtuzumab for refractory chronic lymphocytic leukemia in relation to cytogenetic abnormalities of p53
-
Osuji NC, Del Giudice I, Matutes E et al. The efficacy of alemtuzumab for refractory chronic lymphocytic leukemia in relation to cytogenetic abnormalities of p53. Haematologica 2005; 90: 1435-1436.
-
(2005)
Haematologica
, vol.90
, pp. 1435-1436
-
-
Osuji, N.C.1
Del Giudice, I.2
Matutes, E.3
-
19
-
-
15244362778
-
A pilot study of low-dose subcutaneous alemtuzumab therapy for patients with hemotherapy-refractory chronic lymphocytic leukemia
-
Cortelezzi A, Pasquini MC, Sarina B et al. A pilot study of low-dose subcutaneous alemtuzumab therapy for patients with hemotherapy-refractory chronic lymphocytic leukemia. Haematologica 2005; 90: 410-412.
-
(2005)
Haematologica
, vol.90
, pp. 410-412
-
-
Cortelezzi, A.1
Pasquini, M.C.2
Sarina, B.3
-
20
-
-
33750577939
-
Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia
-
Shanafelt TD, Witzig TE, Fink SR et al. Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia. J Clin Oncol 2006; 24: 4634-4641.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4634-4641
-
-
Shanafelt, T.D.1
Witzig, T.E.2
Fink, S.R.3
-
21
-
-
33750199616
-
Updated guidelines on the management of cytomegalovirus reactivation in patients with chronic lymphocytic leukemia treated with alemtuzumab
-
O'Brien SM, Keating MJ, Mocarski ES. Updated guidelines on the management of cytomegalovirus reactivation in patients with chronic lymphocytic leukemia treated with alemtuzumab. Clin Lymphoma Myeloma 2006; 7: 125-130.
-
(2006)
Clin Lymphoma Myeloma
, vol.7
, pp. 125-130
-
-
O'Brien, S.M.1
Keating, M.J.2
Mocarski, E.S.3
-
22
-
-
11144357712
-
Management guidelines for use of alemtuzumab in B-cell chronic lymphocytic leukemia
-
Keating M, Coutre S, Rai K et al. Management guidelines for use of alemtuzumab in B-cell chronic lymphocytic leukemia. Clin Lymphoma 2004; 4: 220-227.
-
(2004)
Clin Lymphoma
, vol.4
, pp. 220-227
-
-
Keating, M.1
Coutre, S.2
Rai, K.3
-
23
-
-
0029981025
-
National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment
-
Cheson BD, Bennett JM, Grever M et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 1996; 87: 4990-4997.
-
(1996)
Blood
, vol.87
, pp. 4990-4997
-
-
Cheson, B.D.1
Bennett, J.M.2
Grever, M.3
-
24
-
-
38049094162
-
Combined cyclophosphamide, fludarabine, alemtuzumab, and rituximab (CFAR), an active regimen for heavily treated patients with CLL
-
(Abstr 31)
-
Wierda WG, O'Brien S, Faderl S et al. Combined cyclophosphamide, fludarabine, alemtuzumab, and rituximab (CFAR), an active regimen for heavily treated patients with CLL. Blood 2006; 108: 14a (Abstr 31).
-
(2006)
Blood
, vol.108
-
-
Wierda, W.G.1
O'Brien, S.2
Faderl, S.3
-
25
-
-
30644456577
-
11q22.3 deletion in B-chronic lymphocytic leukemia is specifically associated with bulky lymphadenopathy and ZAP-70 expression but not reduced expression of adhesion/cell surface receptor molecules
-
Dickinson JD, Gilmore J, Iqbal J et al. 11q22.3 deletion in B-chronic lymphocytic leukemia is specifically associated with bulky lymphadenopathy and ZAP-70 expression but not reduced expression of adhesion/cell surface receptor molecules. Leuk Lymphoma 2006; 47: 231-244.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 231-244
-
-
Dickinson, J.D.1
Gilmore, J.2
Iqbal, J.3
-
26
-
-
38849131246
-
Alemtuzumab in clinical practice: a British Columbia experience
-
Hui D, Lam W, Toze C et al. Alemtuzumab in clinical practice: a British Columbia experience. Leuk Lymphoma 2008; 49: 218-226.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 218-226
-
-
Hui, D.1
Lam, W.2
Toze, C.3
-
27
-
-
24644500086
-
Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia
-
Sehn LH, Donaldson J, Chhanabhai M et al. Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia. J Clin Oncol 2005; 23: 5027-5033.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5027-5033
-
-
Sehn, L.H.1
Donaldson, J.2
Chhanabhai, M.3
-
28
-
-
0842322860
-
Efficacy and tolerability of alemtuzumab (CAMPATH-1H) in the salvage treatment of B-cell chronic lymphocytic leukemia-change of regimen needed?
-
Rieger K, Von Grü nhagen U, Fietz T et al. Efficacy and tolerability of alemtuzumab (CAMPATH-1H) in the salvage treatment of B-cell chronic lymphocytic leukemia-change of regimen needed? Leuk Lymphoma 2004; 45: 345-349.
-
(2004)
Leuk Lymphoma
, vol.45
, pp. 345-349
-
-
Rieger, K.1
Von Grü nhagen, U.2
Fietz, T.3
-
29
-
-
70450267533
-
Low-dose subcutaneous alemtuzumab in refractory chronic lymphocytic leukaemia (CLL): results of a prospective, single-arm multicentre study
-
Cortelezzi A, Pasquini MC, Gardellini A et al. Low-dose subcutaneous alemtuzumab in refractory chronic lymphocytic leukaemia (CLL): results of a prospective, single-arm multicentre study. Leukemia 2009; 23: 2027-2033.
-
(2009)
Leukemia
, vol.23
, pp. 2027-2033
-
-
Cortelezzi, A.1
Pasquini, M.C.2
Gardellini, A.3
-
30
-
-
65749114275
-
Rituximab, fludarabine, and cyclophosphamide (R-FC) prolongs progression free survival in relapsed or refractory chronic lymphocytic leukemia (CLL) compared with FC alone: final results from the International Randomized Phase III REACH Trial
-
(late-breaking Abstr 1)
-
Robak T, Moiseev SI, Dmoszynska A et al. Rituximab, fludarabine, and cyclophosphamide (R-FC) prolongs progression free survival in relapsed or refractory chronic lymphocytic leukemia (CLL) compared with FC alone: final results from the International Randomized Phase III REACH Trial. Blood 2008: 112 (late-breaking Abstr 1).
-
(2008)
Blood
, vol.112
-
-
Robak, T.1
Moiseev, S.I.2
Dmoszynska, A.3
-
31
-
-
65749110753
-
Bendamustine in combination with rituximab (BR) for patients with relapsed chronic lymphocytic leukemia (CLL): a multicentre phase II trial of the German CLL Study Group (GCLLSG)
-
(Abstr 330)
-
Fischer K, Stilgenbauer S, Schweighofer CD et al. Bendamustine in combination with rituximab (BR) for patients with relapsed chronic lymphocytic leukemia (CLL): a multicentre phase II trial of the German CLL Study Group (GCLLSG). Blood 2008; 112: 128 (Abstr 330).
-
(2008)
Blood
, vol.112
, pp. 128
-
-
Fischer, K.1
Stilgenbauer, S.2
Schweighofer, C.D.3
-
32
-
-
33846219417
-
Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia
-
Byrd JC, Lin TS, Dalton JT et al. Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia. Blood 2007; 109: 399-404.
-
(2007)
Blood
, vol.109
, pp. 399-404
-
-
Byrd, J.C.1
Lin, T.S.2
Dalton, J.T.3
-
33
-
-
33947243663
-
Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase II study
-
Chanan-Khan A, Miller KC, Musial L et al. Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase II study. J Clin Oncol 2006; 24: 5343-5349.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5343-5349
-
-
Chanan-Khan, A.1
Miller, K.C.2
Musial, L.3
-
34
-
-
77949446259
-
Allotransplantation for chronic lymphocytic leukemia
-
Dreger P. Allotransplantation for chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2009; 1: 602-609.
-
(2009)
Hematology Am Soc Hematol Educ Program
, vol.1
, pp. 602-609
-
-
Dreger, P.1
-
35
-
-
36348953152
-
Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping
-
Haferlach C, Dicker F, Schnittger S et al. Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping. Leukemia 2007; 21: 2442-2451.
-
(2007)
Leukemia
, vol.21
, pp. 2442-2451
-
-
Haferlach, C.1
Dicker, F.2
Schnittger, S.3
-
36
-
-
70450262907
-
Retreatment with alemtuzumab after a first, successful alemtuzumab treatment in B-CLL
-
(Abstr 4714)
-
Fiegl M, Falkner F, Falkner A et al. Retreatment with alemtuzumab after a first, successful alemtuzumab treatment in B-CLL. Blood 2007; 110: 252b (Abstr 4714).
-
(2007)
Blood
, vol.110
-
-
Fiegl, M.1
Falkner, F.2
Falkner, A.3
|