Neuroprotective properties of ketone bodies

Advances in Experimental Medicine and Biology

Volumn 737, Issue , 2012, Pages 97-102

  Xu, Kui ^a   Lamanna, Joseph C ^a   Puchowicz, Michelle A ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KETONE BODY; PROPIONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN STEM; CONTROLLED STUDY; FOCAL BRAIN ISCHEMIA; HEART ARREST; IN VIVO STUDY; KETOACIDOSIS; KETOGENIC DIET; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION; REPERFUSION INJURY; RESUSCITATION; TRANSIENT GLOBAL ISCHEMIA; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; BRAIN; BRAIN ISCHEMIA; ENERGY METABOLISM; GLUCOSE; HEART ARREST; KETONE BODIES; KETOSIS; MALE; RATS; RATS, WISTAR; STROKE;

EID: 84856249514     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4614-1566-4_15     Document Type: Article

References (8)

1. Puchowicz MA, Zechel J, Valerio J, Emancipator D, Xu K, Pundik S, LaManna JC, Lust WD (2008) Neuroprotection in diet induced ketotic rat brain following focal ischemia. J Cereb Blood Flow Metab 28(12):1907-1916
2. Deng S, Zhang GF, Kasumov T, Roe CR, Brunengraber H (2009) Interrelations between C4 ketogenesis, C5 ketogenesis, and anaplerosis in the perfused rat liver. J Biol Chem 284(41):27799-27807
3. Brunengraber H, Roe CR (2006) Anaplerotic molecules: current and future. J Inherit Metab Dis 29(2-3):327-331
4. Kasumov T, Sharma N, Huang H, Kombu RS, Cendrowski A, Stanley WC, Brunengraber H (2009) Dipropionylcysteine ethyl ester compensates for loss of citric acid cycle intermediates during post ischemia reperfusion in the pig heart. Cardiovasc Drugs Ther 23(6):459-469
5. Martini WZ, Stanley WC, Huang H, Rosiers CD, Hoppel CL, Brunengraber H (2003) Quantitative assessment of anaplerosis from propionate in pig heart in vivo. Am J Physiol Endocrinol Metab 284(2):E351-E356
6. Roe CR, Mochel F (2006) Anaplerotic diet therapy in inherited metabolic disease: therapeutic potential. J Inherit Metab Dis 29(2-3):332-340
7. Kasumov T, Sharma N, Huang H, Kombu RS, Cendrowski A, Stanley WC, Brunengraber H (2009) Dipropionylcysteine ethyl ester compensates for loss of citric acid cycle intermediates during post ischemia reperfusion in the pig heart. Cardiovasc Drugs Ther 23(6):459-469
8. Xu K, LaManna JC (2009) The loss of hypoxic ventilatory responses following resuscitation after cardiac arrest in rats is associated with failure of long-term survival. Brain Res 3(1258): 59-64