A LC-MS/MS method for the determination of lumefantrine and its metabolite desbutyl-lumefantrine in plasma from patients infected with Plasmodium falciparum malaria

Journal of Liquid Chromatography and Related Technologies

Volumn 34, Issue 20, 2011, Pages 2674-2688

  Sethi, Prerana ^a   Dua, Virendra K ^a   Jain, Rajeev ^b  

^a BHARAT HEAVY ELECTRICALS LIMITED   (India)

^b JIWAJI UNIVERSITY   (India)

Author keywords

desbutyl lumefantrine; halofantrine; HPLC MS MS; lumefantrine; Lumether; P. falciparum malaria

Indexed keywords

DESBUTYL-LUMEFANTRINE; HALOFANTRINE; HPLC-MS/MS; LUMEFANTRINE; LUMETHER; P. FALCIPARUM MALARIA;

ACETONITRILE; ELECTROSPRAY IONIZATION; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES; PATIENT TREATMENT; PLASMAS; SOLVENTS;

ORGANIC SOLVENTS;

ACETONITRILE; ANTIMALARIAL AGENT; ARTEMETHER; BENFLUMETOL; DESBUTYLLUMEFANTRINE; DRUG METABOLITE; LUMETHER; UNCLASSIFIED DRUG;

ARTICLE; BLOOD LEVEL; CHEMICAL STRUCTURE; CLINICAL ARTICLE; DILUTION; DRUG BLOOD LEVEL; DRUG STRUCTURE; ELECTROSPRAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; HUMAN; MALARIA CONTROL; MALARIA FALCIPARUM; PROCESS OPTIMIZATION; QUADRUPOLE MASS SPECTROMETRY; TANDEM MASS SPECTROMETRY;

PLASMODIUM FALCIPARUM;

EID: 84856247547     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2011.593222     Document Type: Article

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