Development and validation of a bioanalytical method using automated solid-phase extraction and LC-UV for the simultaneous determination of lumefantrine and its desbutyl metabolite in plasma

Journal of Pharmaceutical and Biomedical Analysis

Volumn 37, Issue 5, 2005, Pages 1081-1088

  Lindegardh N ^a,b   Annerberg, A ^a   Blessborn, D ^c   Bergqvist, Y ^c   Day, N ^a,b   White, N J ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c DALARNA UNIVERSITY   (Sweden)

Author keywords

Antimalarial; Lipophilic; Liquid chromatography; Lumefantrine; Solid phase extraction; Stability; Validation

Indexed keywords

ACETIC ACID; ACETONITRILE; BENFLUMETOL; DESBUTYLLUMEFANTRINE; DRUG METABOLITE; PLASMA PROTEIN; SODIUM DIHYDROGEN PHOSPHATE; SODIUM PERCHLORATE; UNCLASSIFIED DRUG;

ACCURACY; AUTOMATION; CONFERENCE PAPER; CONTROLLED STUDY; DEVICE; DRUG BLOOD LEVEL; DRUG DETERMINATION; HUMAN; LIPID BLOOD LEVEL; LIQUID CHROMATOGRAPHY; PRECIPITATION; PRIORITY JOURNAL; REPRODUCIBILITY; SOLID PHASE EXTRACTION; ULTRAVIOLET SPECTROSCOPY;

EID: 18144368436     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2004.07.041     Document Type: Conference Paper

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