Long-term high-dose proton pump inhibitor administration to Helicobacter pylori-infected mongolian gerbils enhances neuroendocrine tumor development in the glandular Stomach

Asian Pacific Journal of Cancer Prevention

Volumn 12, Issue 4, 2011, Pages 1049-1054

  Tsukamoto, Hironobu ^a   Mizoshita, Tsutomu ^a   Sasaki, Makoto ^b   Mizushima, Takashi ^a   Tanida, Satoshi ^a   Ozeki, Keiji ^a   Hirata, Yoshikazu ^a   Shimura, Takaya ^a   Kataoka, Hiromi ^a   Kamiya, Takeshi ^a   Nojiri, Shunsuke ^a   Tsukamoto, Tetsuya ^c,e   Tatematsu, Masae ^d   Joh, Takashi ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d JAPAN INDUSTRIAL SAFETY AND HEALTH ASSOCIATION   (Japan)

^e FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Helicobacter pylori; Mongolian gerbil; Neuroendocrine tumors; Proton pump inhibitor

Indexed keywords

EID: 84856242334     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Bardram L, Thomsen P, Stadil F (1986). Gastric endocrine cells in omeprazole-treated and untreated patients with the Zollinger-Ellison syndrome. Digestion, 35, 116-22.
2. Borch K, Renvall H, Kullman E, et al (1987). Gastric carcinoid associated with the syndrome of hypergastrinemic atrophic gastritis. A prospective analysis of 11 cases. Am J Surg Pathol, 11, 435-44.
3. Borch K, Renvall H, Liedberg G (1985). Gastric endocrine cell hyperplasia and carcinoid tumors in pernicious anemia. Gastroenterology, 88, 638-48.
4. Bordi C, Yu JY, Baggi MT, et al (1991). Gastric carcinoids and their precursor lesions. A histologic and immunohistochemical study of 23 cases. Cancer, 67, 663-72.
5. Bralow SP, Gruenstein M, Meranze DR, et al (1970). Adenocarcinoma of glandular stomach and duodenum in Wistar rats ingesting N-methyl-N'-nitro-N-nitrosoguanidine, histopathology and associated secretory changes. Cancer Res, 30, 1215-22.
6. Cao L, Mizoshita T, Tsukamoto T, et al (2008). Development of carcinoid tumors of the glandular stomach and effects of eradication in Helicobacter pylori-infected Mongolian gerbils. Asian Pac J Cancer Prev, 9, 25-30.
7. Eissele R, Brunner G, Simon B, et al (1997). Gastric mucosa during treatment with lansoprazole: Helicobacter pylori is a risk factor for argyrophil cell hyperplasia. Gastroenterology, 112, 707-17.
8. Freston JW (1992). Clinical significance of hypergastrinaemia: relevance to gastrin monitoring during omeprazole therapy. Digestion, 51, 102-14.
9. Gillen DK, McColl E (2001). Problems associated with the clinical use of proton pump inhibitors. Pharmacol Toxicol, 89, 281-6.
10. Hagiwara T, Mukaisho K, Nakayama T, et al (2011). Longterm proton pump inhibitor administration worsens atrophic corpus gastritis and promotes adenocarcinoma development in Mongolian gerbils infected with Helicobacter pylori. Gut, in press.
11. Hakanson R, Larsson LI, Liedberg G, et al (1976). Effects of antrectomy or porta-caval shunting on the histamine-storing endocrine-like cells in oxyntic mucosa of rat stomach. A fluorescence histochemical, electron microscopic and chemical study. J Physiol, 259, 785-800.
12. Havu N (1986). Enterochromaffin-like cell carcinoids of gastric mucosa in rats after life-long inhibition of gastric secretion. Digestion, 35, 42-55.
13. Hirata Y, Mizoshita T, Mizushima T, et al (2009). Gastric-andintestinal mixed endocrine cell phenotypic expression of carcinoid tumors in the rectum. Oncol Rep, 21, 107-12.
14. Hirayama F, Takagi S, Iwao E, et al (1999). Development of poorly differentiated adenocarcinoma and carcinoid due to long-term Helicobacter pylori colonization in Mongolian gerbils. J Gastroenterol, 34, 450-4.
15. Hirayama F, Takagi S, Yokoyama Y, et al (1996). Establishment of gastric Helicobacter pylori infection in Mongolian gerbils. J Gastroenterol, 31, 24-8.
16. Honda S, Fujioka T, Tokieda M, et al (1998). Development of Helicobacter pylori-induced gastric carcinoma in Mongolian gerbils. Cancer Res, 58, 4255-9.
17. Kagawa J, Honda S, Kodama M, et al (2002). Enterocromaffinlike cell tumor induced by Helicobacter pylori infection in Mongolian gerbils. Helicobacter, 7, 390-7.
18. Klinkenberg-Knol EC, Festen HP, Jansen JB, et al (1994). Long-term treatment with omeprazole for refractory reflux esophagitis: efficacy and safety. Ann Intern Med, 121, 161-7.
19. Kuipers EJ (2006). Proton pump inhibitors and gastric neoplasia. Gut, 55, 1217-21.
20. Kuipers EJ, Lundell L, Klinkenberg-Knol EC, et al (1996). Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med, 334, 1018-22.
21. Laine L, Ahnen D, McClain C, et al (2000). Review article: potential gastrointestinal effects of long-term acid suppression with proton pump inhibitors. Aliment Pharmacol Ther, 14, 651-68.
22. Lamberts R, Creutzfeldt W, Stockmann F, et al (1988). Longterm omeprazole treatment in man: effects on gastric endocrine cell populations. Digestion, 39, 126-35.
23. Lanzon-Miller S, Pounder RE, Hamilton MR, et al (1987). Twenty-four-hour intragastric acidity and plasma gastrin concentration before and during treatment with either ranitidine or omeprazole. Aliment Pharmacol Ther, 1, 239-51.
24. McColl KE, E-Omar EM, Gillen D (1997). Alterations in gastric physiology in Helicobacter pylori infection: causes of different diseases or all epiphenomena? Ital J Gastroenterol Hepatol, 29, 459-64.
25. McGowan CC, T. L. CoverM. J Blaser (1996). Helicobacter pylori and gastric acid: biological and therapeutic implications. Gastroenterology, 110, 926-38.
26. Mizoshita T, Tsukamota T, Nakanishi H, et al (2003). Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J Cancer Res Clin Oncol, 129, 727-34.
27. Mizoshita T, Tsukamoto T, Takenaka Y, et al (2006). Gastric and intestinal phenotypes and histogenesis of advanced glandular stomach cancers in carcinogen-treated, Helicobacter pyloriinfected Mongolian gerbils. Cancer Sci, 97, 38-44.
28. Nilsson O, Wangberg B, Johansson L, et al (1993). Rapid induction of enterochromaffinlike cell tumors by histamine2-receptor blockade. Am J Pathol, 142, 1173-85.
29. Nozaki K, Shimizu N, Tsukamoto T, et al (2002). Reversibility of heterotopic proliferative glands in glandular stomach of Helicobacter pylori-infected Mongolian gerbils on eradication. Jpn J Cancer Res, 93, 374-81.
30. Poulsen AH, Christensen S, McLaughlin JK, et al (2009). Proton pump inhibitors and risk of gastric cancer: a populationbased cohort study. Br J Cancer, 100, 1503-7.
31. Rindi G, Kloppel G, Alhman H, et al (2006). TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Arch, 449, 395-401.
32. Rindi G, Kloppel G, Couvelard A, et al (2007). TNM staging of midgut and hindgut (neuro) endocrine tumors: a consensus proposal including a grading system. Virchows Arch, 451, 757-62.
33. Sasaki M, Mizoshita T, Mizushima T, et al (2007). Effect of plaunotol in combination with clarithromycin against clarithromycin-resistant Helicobacter pylori in vitro and in vivo. J Antimicrob Chemother, 60, 1060-3.
34. Sato Y, Iwafuchi M, Ueki J, et al (2002). Gastric carcinoid tumors without autoimmune gastritis in Japan: a relationship with Helicobacter pylori infection. Dig Dis Sci, 47, 579-85.
35. Simonsson M, Eriksson S, Hakanson R, et al (1988). Endocrine cells in the human oxyntic mucosa. A histochemical study. Scand J Gastroenterol, 23, 1089-99.
36. Solcia E, Capella C, Fiocca R, et al (1990). Gastric argyrophil carcinoidosis in patients with Zollinger-Ellison syndrome due to type 1 multiple endocrine neoplasia. A newly recognized association. Am J Surg Pathol, 14, 503-13.
37. Takenaka Y, Tsukamoto T, Mizoshita T, et al (2006). Helicobacter pylori infection stimulates intestinalization of endocrine cells in glandular stomach of Mongolian gerbils. Cancer Sci, 97, 1015-22.
38. Takenaka Y, Tsukamoto T, Mizoshita T, et al (2007). Gastric and intestinal phenotypic correlation between exocrine and endocrine components in human stomach tumors. Histol Histopathol, 22, 273-84.
39. Tatematsu M, Tsukamoto T, Mizoshita T (2005). Role of Helicobacter pylori in gastric carcinogenesis: the origin of gastric cancers and heterotopic proliferative glands in Mongolian gerbils. Helicobacter, 10, 97-106.
40. Uemura N, Okamoto S, Yamamoto S, et al (2001). Helicobacter pylori infection and the development of gastric cancer. N Engl J Med, 345, 784-9.
41. Waldum HL, Gustafsson B, Fossmark R, et al (2005). Antiulcer drugs and gastric cancer. Dig Dis Sci, 50, S39-44.
42. Watanabe T, Tada M, Nagai H, et al (1998). Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology, 115, 642-8.
43. Ye W, Nyren O (2003). Risk of cancers of the oesophagus and stomach by histology or subsite in patients hospitalised for pernicious anaemia. Gut, 52, 938-41.