Development of poorly differentiated adenocarcinoma and carcinoid due to long-term Helicobacter pylori colonization in Mongolian gerbils

Journal of Gastroenterology

Volumn 34, Issue 4, 1999, Pages 450-454

  Hirayama, Fumihiro ^a   Takagi, Shiro ^a   Iwao, Eiji ^a   Yokoyama, Yoshito ^a   Haga, Keiichiro ^a   Hanada, Shuichi ^a  

^a Yoshitomi Pharmaceutical Indust L   (Japan)

Author keywords

Carcinoid; H. pylori; Mongolian gerbil; Poorly differentiated adenocarcinoma

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; CANCER RISK; CARCINOID; CHRONIC DISEASE; CONTROLLED STUDY; GASTROINTESTINAL CARCINOMA; GERBIL; HELICOBACTER PYLORI; INOCULATION; MALE; NONHUMAN; PRIORITY JOURNAL; PYLORUS; STOMACH FUNDUS; TUMOR DIFFERENTIATION;

ADENOCARCINOMA; ANIMALS; ANTIBODIES, BACTERIAL; CARCINOID TUMOR; DISEASE MODELS, ANIMAL; DUODENUM; GASTRINS; GERBILLINAE; HELICOBACTER INFECTIONS; IMMUNOGLOBULIN G; INTESTINAL MUCOSA; METAPLASIA; STOMACH NEOPLASMS; TIME;

EID: 0032818245     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350050295     Document Type: Article

References (19)

1. Warren JR, Marshall BJ. Unidentified curved bacilli on gastric epithelium in active gastritis. Lancet 1983;1:1273-5.
2. Rauws EAJ, Langenberg W, Houthoff HJ, et al. Campylobacter pyloridis-associated active antral gastritis. Gastroenterology 1988; 94:33-40.
3. Schubert TT, Bologna SD, Nensey Y, et al. Ulcer risk factors: Interactions between Helicobacter pylori infection, non-steroid use, and age. Am J Med 1993;94:418-23.
4. Parsonet J, Hansen S, Rodriguez L, et al. Helicobacter pvlori infection and gastric lymphoma. N Engl J Med 1994;330:1267-71.
5. The EUROGAST Study Group. An international association between Helicobacter pylori infection and gastric cancer. Lancet 1993;341:1359-62.
6. Parkin DM, Läärä E, Muir CS. Estimates of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer 1988;41:184-97.
7. Hirayama F, Takagi S, Yokoyama Y, et al. Establishment of gastric Helicobacter priori infection in Mongolian gerbils. J Gastroenterol 1996;31(Suppl XI):24-8.
8. Hirayama F, Takagi S, Kushuhara H, et al. Induction of gastric ulcer and intestinal metaplasia in Mongolian gerbils infected with Helicobacter pylori. J Gastroenterol 1996;31:755-7.
9. Evans DJ, Evans DG, Graham DY, et al. A sensitive and specific serologic test for detection of Campylobacter pylori infection. Gastroenterology 1989;96:1004-8.
10. Craanen ME, Dekker W, Blok P, et al. Intestinal metaplasia and Helicobacter priori: an endoscopic bioptic study of the gastric antrum. Gut 1992;33:16-20.
11. Ekman L, Hansson E, Havu N, et al. Toxicological studies on omeprazole. Scand J Gastroenterol 1985;20(Suppl 108):53-9.
12. Mattsson H, Havy N, Brautigam J, et al. Partial gastric corpectomy results in hypergastrinemia and development of gastric enterochromaffin-like-cell carcinoid in the rat. Gastroenterology 1991;100:311-9.
13. Hirayama F, Takagi S, Yokoyama Y, et al. A basic study of gastric ulcer model with Helicobacter pylori infection in Mongolian gerbils (in Japanese with English abstract). Ulcer Res 1998;25:37-43.
14. Tatematsu M, Yamamoto M, Shimizu N, et al. Induction of glandular stomach cancers in Helicobacter pylori-sensitive Mongolian gerbils treated with N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine in drinking water. Jpn J Cancer Res 1998;89:97-104.
15. Watanabe T, Tada M, Nagai H, et al. Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology 1998;115:642-8.
16. Honda S, Fujioka T, Tokieda M, et al. Development of Helicobacter pylori-induced gastric carcinoma in Mongolian gerbils. Cancer Res 1998;58:4255-9.
17. Lauren P. The two main histological types of gastric carcinoma: diffused and so-called intestinal-type carcinoma. An attempt at a histoclinical classification. Acta Pathol Microbiol Scand 1965;64: 31-49.
18. Ming SC, Goldman H, Freima DG. Intestinal metaplasia and histogenesis of carcinoma in human stomach. Light and electron microscopic study. Cancer 1967;20:1418-29.
19. Sugiyama A, Maruta F, Ikeno T, et al. Helicobacter pylori infection enhances N-methyl-N-nitrosourea-induced stomach carcinogencsis in the Mongolian gerbil. Cancer Res 1998;58:2067-9.