Effect of reactive oxygen species produced by spermatozoa and leukocytes on sperm functions in non-leukocytospermic patients

Fertility and Sterility

Volumn 83, Issue 3, 2005, Pages 635-642

  Henkel, Ralf ^a,b   Kierspel, Eva ^a   Stalf, Thomas ^a   Mehnert, Claas ^a   Menkveld, Roelof ^c   Tinneberg, Hans Rudolf ^a   Schill, Wolf Bernhard ^a   Kruger, Thinus F ^c  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

DNA fragmentation; Human spermatozoa; Leukocytospermia; Reactive oxygen species; Sperm functions

Indexed keywords

DNA FRAGMENT; REACTIVE OXYGEN METABOLITE;

ADULT; ARTICLE; CELL FUNCTION; CORRELATION ANALYSIS; EJACULATION; FERTILIZATION IN VITRO; GERMANY; HUMAN; LEUKOCYTE; LEUKOCYTE COUNT; LEUKOCYTE DISORDER; LEUKOCYTOSPERMIA; MAJOR CLINICAL STUDY; MALE; MORPHOLOGY; PRIORITY JOURNAL; SPERMATOZOON; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; WORLD HEALTH ORGANIZATION;

EID: 14844336370     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2004.11.022     Document Type: Article

References (56)

1. R.J. Aitken, J.S. Clarkson, S. Fishel Generation of reactive oxygen species, lipid peroxidation, and human sperm function Biol Reprod 41 1989 183 197
2. R.J. Aitken, D.S. Irvine, F.C. Wu Prospective analysis of sperm-oocyte fusion and reactive oxygen species generation as criteria for the diagnosis of infertility Am J Obstet Gynecol 164 1991 542 551
3. C. Krausz, C. Mills, S. Rogers, S.L. Tan, R.J. Aitken Stimulation of oxidant generation by human sperm suspensions using phorbol esters and formyl peptides: relationships with motility and fertilization in vitro Fertil Steril 62 1994 599 605
4. H. Kodama, R. Yamaguchi, J. Fukuda, H. Kasai, T. Tanaka Increased oxidative deoxyribonucleic acid damage in the spermatozoa of infertile male patients Fertil Steril 68 1997 519 524
5. S. Lopes, A. Jurisicova, J.G. Sun, R.F. Casper Reactive oxygen species: potential cause for DNA fragmentation in human spermatozoa Hum Reprod 13 1998 896 900
6. R.J. Aitken, J.S. Clarkson Significance of reactive oxygen species and antioxidants in defining the efficacy of sperm preparation techniques J Androl 9 1988 367 376
7. M. Plante, E. de Lamirande, C. Gagnon Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility Fertil Steril 62 1994 387 393
8. P. Vigil, C. Wöhler, E. Bustos-Obregón, F. Comhaire, P. Morales Assessment of sperm function in fertile and infertile men Andrologia 26 1994 55 60
9. R.J. Aitken, M. Paterson, H. Fisher, D.W. Buckingham, M. van Duin Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function J Cell Sci 108 1995 2017 2025
10. B. Lewis, R.J. Aitken A redox-regulated tyrosine phosphorylation cascade in rat spermatozoa J Androl 22 2001 611 622
11. H. Ecroyd, R.C. Jones, R.J. Aitken Tyrosine phosphorylation of HSP-90 during mammalian sperm capacitation Biol Reprod 69 2003 1801 1807
12. K. Whittington, W.C. Ford Relative contribution of leukocytes and of spermatozoa to reactive oxygen species production in human sperm suspensions Int J Androl 22 1999 229 235
13. R. Henkel, E. Kierspel, M. Hajimohammad, T. Stalf, C. Hoogendijk, C. Mehnert DNA fragmentation of spermatozoa and assisted reproduction technology RBM Online 7 2003 44 51 Comp. 1
14. H. Wolff The biologic significance of white blood cells in semen Fertil Steril 63 1995 1143 1157
15. E. de Lamirande, C. Gagnon Capacitation-associated production of superoxide anion by human spermatozoa Free Rad Biol Med 18 1995 487 495
16. World Health Organization WHO laboratory manual for the examination of human semen and sperm-cervical mucus interaction 1999 Cambridge University Press Cambridge, UK
17. M.J. Tomlinson, C.L. Barratt, I.D. Cooke Prospective study of leukocytes and leukocyte subpopulations in semen suggests they are not a cause of male infertility Fertil Steril 60 1993 1069 1075
18. J.W. Trum, B.W.J. Mol, Y. Pannekoek, L. Spanjaard, P. Wertheim, O.P. Bleker Value of detecting leukocytospermia in the diagnosis of genital tract infection in subfertile men Fertil Steril 70 1998 315 319
19. A.A. Kiessling, N. Lamparelli, H.Z. Yin, M.M. Seibel, R.C. Eyre Semen leukocytes: friends or foes? Fertil Steril 64 1995 196 198
20. S. Kaleli, F. Öçer, T. Irez, E. Budak, M.F. Aksu Does leukocytospermia associate with poor semen parameters and sperm functions in male infertility? The role of different seminal leukocyte concentrations Eur J Obstet Gynecol Reprod Biol 89 2000 185 191
21. N. Sukcharoen, J. Keith, D.S. Irvine, R.J. Aitken Predicting the fertilizing potential of human sperm suspensions in vitro: importance of sperm morphology and leukocyte contamination Fertil Steril 63 1995 1293 1300
22. R.K. Sharma, A.E. Pasqualotto, D.R. Nelson, A.J. Thomas Jr, A. Agarwal Relationship between seminal white blood cell counts and oxidative stress in men treated at an infertility clinic J Androl 22 2001 575 583
23. R. Menkveld, T.F. Kruger Sperm morphology and male urogenital infections Andrologia 30 Suppl 1 1998 49 53
24. M. Punab, K. Loivukene, K. Kermes, R. Mändar The limit of leukocytospermia from the microbiological viewpoint Andrologia 35 2003 271 278
25. N. Hofmann, B. Hilscher, B. Morchen, H.C. Schuppe, P. Bielfeld Comparative studies on various modes of classification of morphology of sperm heads and results in in vitro fertilization--a preliminary report Andrologia 27 1995 19 23
26. W. Ombelet, R. Menkveld, T.F. Kruger, O. Steeno Sperm morphology assessment: historical review in relation to fertility Hum Reprod Update 1 1995 543 557
27. P. Quinn, J.F. Kerin, G.M. Warnes Improved pregnancy rate in human in vitro fertilization with the use of a medium based on the composition of human tubal fluid Fertil Steril 44 1985 493 498
28. R. Henkel, M. Hajimohammad, T. Stalf, C. Mehnert, R. Menkveld, H. Gips Influence of DNA damage on fertilization and pregnancy Fertil Steril 81 2004 965 972
29. G. Rothe, G. Valet Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescein J Leukoc Biol 47 1990 440 448
30. E.H. Yanushpolsky, J.A. Politch, J.A. Hill, D.J. Anderson Is leukocytospermia clinically relevant? Fertil Steril 66 1996 822 825
31. J. Villegas, M. Schulz, V. Vallejos, R. Henkel, W. Miska, R. Sánchez Indirect immunofluorescence using monoclonal antibodies for the detection of leukocytospermia: comparison with peroxidase staining Andrologia 34 2002 69 73
32. R.J. Aitken, D.W. Buckingham, J. Brindle, E. Gomez, H.W. Baker, D.S. Irvine Analysis of sperm movement in relation to the oxidative stress created by leukocytes in washed sperm preparations and seminal plasma Hum Reprod 10 1995 2061 2071
33. J.G. Alvarez, R.K. Sharma, M. Ollero, R.A. Saleh, M.C. Lopez, A.J. Thomas Jr Increased DNA damage in sperm from leukocytospermic semen samples as determined by the sperm chromatin structure assay Fertil Steril 78 2002 319 329
34. J.G. Sun, A. Jurisicova, R.F. Casper Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro Biol Reprod 56 1997 602 607
35. S. Lopes, J.G. Sun, A. Jurisicova, J. Meriano, R.F. Casper Sperm deoxyribonucleic acid fragmentation is increased in poor-quality semen samples and correlates with failed fertilization in intracytoplasmic sperm injection Fertil Steril 69 1998 528 532
36. E.H. Duran, M. Morshedi, S. Taylor, S. Oehninger Sperm DNA quality predicts intrauterine insemination outcome: a prospective cohort study Hum Reprod 17 2002 3122 3128
37. I.D. Morris, S. Ilott, L. Dixon, D.R. Brison The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (Comet assay) and its relationship to fertilization and embryo development Hum Reprod 17 2002 990 998
38. D.S. Irvine, J.P. Twigg, E.L. Gordon, N. Fulton, P.A. Milne, R.J. Aitken DNA integrity in human spermatozoa: relationships with semen quality J Androl 21 2000 33 44
39. R.A. Saleh, A. Agarwal, E. Kandirali, R.K. Sharma, A.J. Thomas Jr, E.A. Nada Leukocytospermia is associated with increased reactive oxygen species production by human spermatozoa Fertil Steril 78 2002 1215 1224
40. A. Iwasaki, C. Gagnon Formation of reactive oxygen species in spermatozoa of infertile patients Fertil Steril 57 1992 409 416
41. J. Keating, C.E. Grundy, P.S. Fivey, M. Elliott, J. Robinson Investigation of the association between the presence of cytoplasmic residues on the human sperm midpiece and defective sperm function J Reprod Fertil 110 1997 71 77
42. E. Gil-Guzman, M. Ollero, M.C. Lopez, R.K. Sharma, J.G. Alvarez, A.J. Thomas Jr Differential production of reactive oxygen species by subsets of human spermatozoa at different stages of maturation Hum Reprod 16 2001 1922 1930
43. N. Esfandiari, R.K. Sharma, R.A. Saleh, A.J. Thomas Jr, A. Agarwal Utility of the nitroblue tetrazolium reduction test for assessment of reactive oxygen species production by seminal leukocytes and spermatozoa J Androl 24 2003 862 870
44. N. Aziz, R.A. Saleh, R.K. Sharma, I. Lewis-Jones, N. Esfandiari, A.J. Thomas Jr Novel association between sperm reactive oxygen species production, sperm morphological defects, and the sperm deformity index Fertil Steril 81 2004 349 354
45. E. Gomez, D. Buckingham, F. Brindle J Lanzafame, D.S. Irvine, R.J. Aitken Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: correlation with biochemical markers of the cytoplasmic space, oxidative stress and sperm function J Androl 17 1996 276 287
46. R.J. Aitken, H.M. Fisher, N. Fulton, E. Gomez, W. Knox, B. Lewis Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine Mol Reprod Dev 47 1997 468 482
47. L. Ramos, A.M.M. Wetzels Low rates of DNA fragmentation in selected motile human spermatozoa assessed by the TUNEL assay Hum Reprod 16 2001 1703 1707
48. A. Giwercman, J. Richthoff, H. Hjøllund, J.P. Bonde, K. Jepson Correlation between sperm motility and sperm chromatin structure assay parameters Fertil Steril 80 2003 1404 1412
49. J. Erenpreiss, S. Hlevicka, J. Zalkalns, J. Erenpreisa Effect of leukocytospermia on sperm DNA integrity: a negative effect in abnormal semen samples J Androl 23 2002 717 723
50. B. Zorn, I. Virant-Klun, H. Meden-Vrtovec Semen granulocyte elastase: its relevance for the diagnosis and prognosis of silent genital tract inflammation Hum Reprod 15 2000 1978 1984
51. R.J. Aitken, E. Gordon, D. Harkiss, J.P. Twigg, P. Milne, Z. Jennings Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa Biol Reprod 59 1998 1037 1046
52. R.J. Aitken, C. Krausz Oxidative stress, DNA damage and the Y chromosome Reproduction 122 2001 497 506
53. R. Henkel, W.-B. Schill Sperm preparation for ART Reprod Biol Endocrinol 1 2003 108
54. H.W.G. Baker, J. Brindle, D.S. Irvine, R.J. Aitken Protective effect of antioxidants on the impairment of sperm motility by activated polymorphonuclear leukocytes Fertil Steril 65 1996 411 419
55. F.F. Pasqualotto, R.K. Sharma, D.R. Nelson, A.J. Thomas Jr, A. Agarwal Relationship between oxidative stress, semen characteristics, and clinical diagnosis in men undergoing infertility investigation Fertil Steril 73 2000 459 464
56. G. Haidl Macrophages in semen are indicative of chronic epididymal infection Arch Androl 25 1990 5 11