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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 3, 2012, Pages 1365-1370

Discovery of novel selective inhibitors for EGFR-T790M/L858R

(11) Bai, Fang a Liu, Hongyan b Tong, Linjiang b Zhou, Wei c Liu, Li c Zhao, Zhenjiang c Liu, Xiaofeng c Jiang, Hualiang b,c Wang, Xicheng a Xie, Hua b Li, Honglin c

a DALIAN UNIVERSITY OF TECHNOLOGY (China)

b SHANGHAI INSTITUTE OF MATERIA MEDICA (China)

c EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (China)

Author keywords

Dual effective inhibitors; EGFR; Kinase inhibitors; Selective inhibitors; T790M L858R; Virtual screening

Indexed keywords

1,4 DIHYDROXY 5 METHOXY ANTHRAQUINONE; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; LAPATINIB; NERATINIB; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; DRUG STRUCTURE; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; LUNG CANCER; SQUAMOUS CELL CARCINOMA; STRUCTURE ACTIVITY RELATION;

CATALYTIC DOMAIN; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG DISCOVERY; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84856213777 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.12.067 Document Type: Article

Times cited : (29)

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