Amygdala response to smoking-cessation messages mediates the effects of serotonin transporter gene variation on quitting

NeuroImage

Volumn 60, Issue 1, 2012, Pages 766-773

  Jasinska, Agnes J ^a,b   Chua, Hannah Faye ^b   Ho, S Shaun ^c   Polk, Thad A ^b   Rozek, Laura S ^b   Strecher, Victor J ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Amygdala; FMRI; Imaging genetics; Serotonin transporter gene; Smoking cessation

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CONTROLLED STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GENE; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HEALTH BEHAVIOR; HUMAN; MALE; NEUROMODULATION; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; SEROTONIN TRANSPORTER GENE; SEROTONINERGIC SYSTEM; SMOKING CESSATION;

ADULT; AMYGDALA; FEMALE; GENOTYPE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SMOKING; SMOKING CESSATION;

EID: 84856112777     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2011.12.064     Document Type: Article

References (50)

1. Baron R.M., Kenny D.A. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J. Pers. Soc. Psychol. 1986, 51:1173-1182.
2. Baxter M.G., Murray E.A. The amygdala and reward. Nat. Rev. Neurosci. 2002, 3:563-573.
3. Bigos K.L., Weinberger D.R. Imaging genetics-days of future past. Neuroimage 2010, 53:804-809.
4. Cahill L., McGaugh J.L. A novel demonstration of enhanced memory associated with emotional arousal. Conscious. Cogn. 1995, 4:410-421.
5. CDC Cigarette smoking-attributable morbidity-United States, 2000. MMWR Morb. Mortal. Wkly Rep. 2003, 52:842-844.
6. CDC Smoking-attributable mortality, years of potential life lost, and productivity losses-United States, 2000-2004. MMWR Morb. Mortal. Wkly Rep. 2008, 57:1226-1228.
7. Childress A.R., Mozley P.D., McElgin W., Fitzgerald J., Reivich M., O'Brien C.P. Limbic activation during cue-induced cocaine craving. Am. J. Psychiatry 1999, 156:11-18.
8. Chua H.F., Ho S.S., Jasinska A.J., Polk T.A., Welsh R.C., Liberzon I., Strecher V.J. Self-related neural response to tailored smoking-cessation messages predicts quitting. Nat. Neurosci. 2011, 14:426-427.
9. Cools R., Roberts A.C., Robbins T.W. Serotoninergic regulation of emotional and behavioural control processes. Trends Cogn. Sci. 2008, 12:31-40.
10. Dannlowski U., Konrad C., Kugel H., Zwitserlood P., Domschke K., Schoning S., Ohrmann P., Bauer J., Pyka M., Hohoff C., Zhang W., Baune B.T., Heindel W., Arolt V., Suslow T. Emotion specific modulation of automatic amygdala responses by 5-HTTLPR genotype. Neuroimage 2010, 53:893-898.
11. Dayan P., Huys Q.J. Serotonin in affective control. Annu. Rev. Neurosci. 2009, 32:95-126.
12. Falk E.B., Berkman E.T., Whalen D., Lieberman M.D. Neural activity during health messaging predicts reductions in smoking above and beyond self-report. Health Psychol. 2010, 30:177-185.
13. Ferguson S.G., Shiffman S. The relevance and treatment of cue-induced cravings in tobacco dependence. J. Subst. Abuse Treat. 2009, 36:235-243.
14. Fiskerstrand C.E., Lovejoy E.A., Quinn J.P. An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells. FEBS Lett. 1999, 458:171-174.
15. Franklin T.R., Wang Z., Wang J., Sciortino N., Harper D., Li Y., Ehrman R., Kampman K., O'Brien C.P., Detre J.A., Childress A.R. Limbic activation to cigarette smoking cues independent of nicotine withdrawal: a perfusion fMRI study. Neuropsychopharmacology 2007, 32:2301-2309.
16. Franklin T.R., Wang Z., Li Y., Suh J.J., Goldman M., Lohoff F.W., Cruz J., Hazan R., Jens W., Detre J.A., Berrettini W., O'Brien C.P., Childress A.R. Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort. Addict. Biol. 2011, 16:308-322.
17. Gelernter J., Cubells J.F., Kidd J.R., Pakstis A.J., Kidd K.K. Population studies of polymorphisms of the serotonin transporter protein gene. Am. J. Med. Genet. 1999, 88:61-66.
18. Ghashghaei H.T., Hilgetag C.C., Barbas H. Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala. Neuroimage 2007, 34:905-923.
19. Goudriaan A.E., de Ruiter M.B., van den Brink W., Oosterlaan J., Veltman D.J. Brain activation patterns associated with cue reactivity and craving in abstinent problem gamblers, heavy smokers and healthy controls: an fMRI study. Addict. Biol. 2010, 15:491-503.
20. Hariri A.R. The neurobiology of individual differences in complex behavioral traits. Annu. Rev. Neurosci. 2009, 32:225-247.
21. Hariri A.R., Mattay V.S., Tessitore A., Kolachana B., Fera F., Goldman D., Egan M.F., Weinberger D.R. Serotonin transporter genetic variation and the response of the human amygdala. Science 2002, 297:400-403.
22. Hariri A.R., Drabant E.M., Munoz K.E., Kolachana B.S., Mattay V.S., Egan M.F., Weinberger D.R. A susceptibility gene for affective disorders and the response of the human amygdala. Arch. Gen. Psychiatry 2005, 62:146-152.
23. Hariri A.R., Drabant E.M., Weinberger D.R. Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. Biol. Psychiatry 2006, 59:888-897.
24. Heils A., Teufel A., Petri S., Stober G., Riederer P., Bengel D., Lesch K.P. Allelic variation of human serotonin transporter gene expression. J. Neurochem. 1996, 66:2621-2624.
25. Hranilovic D., Stefulj J., Schwab S., Borrmann-Hassenbach M., Albus M., Jernej B., Wildenauer D. Serotonin transporter promoter and intron 2 polymorphisms: relationship between allelic variants and gene expression. Biol. Psychiatry 2004, 55:1090-1094.
26. Hu X.Z., Lipsky R.H., Zhu G., Akhtar L.A., Taubman J., Greenberg B.D., Xu K., Arnold P.D., Richter M.A., Kennedy J.L., Murphy D.L., Goldman D. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am. J. Hum. Genet. 2006, 78:815-826.
27. Jacobs B.L., Azmitia E.C. Structure and function of the brain serotonin system. Physiol. Rev. 1992, 72:165-229.
28. Janes A.C., Pizzagalli D.A., Richardt S., de, B.F.B., Chuzi S., Pachas G., Culhane M.A., Holmes A.J., Fava M., Evins A.E., Kaufman M.J. Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biol. Psychiatry 2010, 67:722-729.
29. Kaiser R., Tremblay P.B., Schmider J., Henneken M., Dettling M., Muller-Oerlinghausen B., Uebelhack R., Roots I., Brockmoller J. Serotonin transporter polymorphisms: no association with response to antipsychotic treatment, but associations with the schizoparanoid and residual subtypes of schizophrenia. Mol. Psychiatry 2001, 6:179-185.
30. Kazantseva A.V., Gaysina D.A., Faskhutdinova G.G., Noskova T., Malykh S.B., Khusnutdinova E.K. Polymorphisms of the serotonin transporter gene (5-HTTLPR, A/G SNP in 5-HTTLPR, and STin2 VNTR) and their relation to personality traits in healthy individuals from Russia. Psychiatr. Genet. 2008, 18:167-176.
31. Kilts C.D., Schweitzer J.B., Quinn C.K., Gross R.E., Faber T.L., Muhammad F., Ely T.D., Hoffman J.M., Drexler K.P. Neural activity related to drug craving in cocaine addiction. Arch. Gen. Psychiatry 2001, 58:334-341.
32. Kranz G.S., Kasper S., Lanzenberger R. Reward and the serotonergic system. Neuroscience 2010, 166:1023-1035.
33. LeDoux J.E. Emotion circuits in the brain. Annu. Rev. Neurosci. 2000, 23:155-184.
34. Lesch K.P., Balling U., Gross J., Strauss K., Wolozin B.L., Murphy D.L., Riederer P. Organization of the human serotonin transporter gene. J. Neural Transm. Gen. Sect. 1994, 95:157-162.
35. Lesch K.P., Bengel D., Heils A., Sabol S.Z., Greenberg B.D., Petri S., Benjamin J., Muller C.R., Hamer D.H., Murphy D.L. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996, 274:1527-1531.
36. Maldjian J.A., Laurienti P.J., Kraft R.A., Burdette J.H. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 2003, 19:1233-1239.
37. McGaugh J.L. The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu. Rev. Neurosci. 2004, 27:1-28.
38. Niaura R., Shadel W.G., Abrams D.B., Monti P.M., Rohsenow D.J., Sirota A. Individual differences in cue reactivity among smokers trying to quit: effects of gender and cue type. Addict. Behav. 1998, 23:209-224.
39. Noll D.C., Genovese C.R., Vazquez A.L., O'Brien J.L., Eddy W.F. Evaluation of respiratory artifact correction techniques in multishot spiral functional MRI using receiver operator characteristic analyses. Magn. Reson. Med. 1998, 40:633-639.
40. Phelps E.A. Emotion and cognition: insights from studies of the human amygdala. Annu. Rev. Psychol. 2006, 57:27-53.
41. Preacher K.J., Hayes A.F. Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav. Res. Methods 2008, 40:879-891.
42. Quaak M., van Schayck C.P., Knaapen A.M., van Schooten F.J. Genetic variation as a predictor of smoking cessation success. A promising preventive and intervention tool for chronic respiratory diseases?. Eur. Respir. J. 2009, 33:468-480.
43. Robbins T.W., Ersche K.D., Everitt B.J. Drug addiction and the memory systems of the brain. Ann. N. Y. Acad. Sci. 2008, 1141:1-21.
44. Rogers R.D. The roles of dopamine and serotonin in decision making: evidence from pharmacological experiments in humans. Neuropsychopharmacology 2011, 36:114-132.
45. Rose J.E. Nicotine and nonnicotine factors in cigarette addiction. Psychopharmacology (Berl) 2006, 184:274-285.
46. See R.E., Fuchs R.A., Ledford C.C., McLaughlin J. Drug addiction, relapse, and the amygdala. Ann. N. Y. Acad. Sci. 2003, 985:294-307.
47. Strecher V.J., McClure J.B., Alexander G.L., Chakraborty B., Nair V.N., Konkel J.M., Greene S.M., Collins L.M., Carlier C.C., Wiese C.J., Little R.J., Pomerleau C.S., Pomerleau O.F. Web-based smoking-cessation programs: results of a randomized trial. Am. J. Prev. Med. 2008, 34:373-381.
48. Velicer W.F., Prochaska J.O. A comparison of four self-report smoking cessation outcome measures. Addict. Behav. 2004, 29:51-60.
49. Verdejo-Garcia A., Bechara A. A somatic marker theory of addiction. Neuropharmacology 2009, 56(Suppl. 1):48-62.
50. Yonan A.L., Palmer A.A., Gilliam T.C. Hardy-Weinberg disequilibrium identified genotyping error of the serotonin transporter (SLC6A4) promoter polymorphism. Psychiatr. Genet. 2006, 16:31-34.