The accessibility in the external part of the TM5 of the glutamate transporter EAAT1 is conformationally sensitive during the transport cycle

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Zhang, Xiuping ^a   Qu, Shaogang ^b  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

(2 TRIMETHYLAMMONIUM)METHANETHIOSULFONATE; CYSTEINE; EXCITATORY AMINO ACID TRANSPORTER 1; GLUTAMIC ACID; MEMBRANE PROTEIN; THIOL REAGENT; TRANSMEMBRANE DOMAIN 5; UNCLASSIFIED DRUG; ASPARTIC ACID; TRITIUM;

ARTICLE; CONTROLLED STUDY; INHIBITION KINETICS; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MUTAGENICITY; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TRANSPORT; SENSITIVITY ANALYSIS; STRUCTURE ACTIVITY RELATION; TRANSPORT KINETICS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HELA CELL; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; TRANSPORT AT THE CELLULAR LEVEL;

ASPARTIC ACID; BINDING SITES; BIOLOGICAL TRANSPORT; EXCITATORY AMINO ACID TRANSPORTER 1; GLUTAMIC ACID; HELA CELLS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; TRITIUM;

EID: 84856096107     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030961     Document Type: Article

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