Phytocomponent p-Hydroxycinnamic acid inhibits T-cell activation by modulation of protein kinase C-θ-dependent pathway

International Immunopharmacology

Volumn 12, Issue 1, 2012, Pages 131-138

  Lee, Hyun Su ^a   Kim, Young Dae ^a   Na, Bo Ra ^a   Kim, Hye Ran ^a   Choi, Eun Ju ^b   Han, Weon Cheol ^c   Choi, Hyun Kyu ^d   Lee, Seung Ho ^d   Jun, Chang Duk ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Konkuk University   (South Korea)

^c Wonkwang University School of Medicine   (South Korea)

^d Yeungnam University   (South Korea)

Author keywords

Apoptosis; IL 2; Immunosuppression; p Hydroxycinnamic acid; Protein kinase C ; T cell activation

Indexed keywords

COUMARIC ACID; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; TRANSCRIPTION FACTOR AP 1;

ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; LEUKOCYTE; LYMPHOCYTE ACTIVATION; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROMOTER REGION; T LYMPHOCYTE ACTIVATION;

CELL LINE; CELL SURVIVAL; COUMARIC ACIDS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-2; ISOENZYMES; JURKAT CELLS; LEUKOCYTES, MONONUCLEAR; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C; RNA, MESSENGER; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1;

EID: 84856094674     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.11.001     Document Type: Article

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