An in vitro comparative study with furyl-1,4-quinones endowed with anticancer activities

Investigational New Drugs

Volumn 29, Issue 5, 2011, Pages 760-767

  Benites, Julio ^a   Valderrama, Jaime A ^a,b   Taper, Henryk ^c   Buc Calderon, Pedro ^a,c  

^a UNIVERSIDAD ARTURO PRAT   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Apoptosis; Cancer therapy; Cell death; Oxidative stress; Quinones

Indexed keywords

1,4 NAPHTHOQUINONE; 2 (5 FORMYLFUR 2 YL) 1,4 NAPHTHOQUINONE; 2 (5 FORMYLFUR 2 YL) 5 METHOXY 1,4 BENZOQUINONE; 2 (5 N,N DIMETHYLHYDRAZONOFUR 2 YL) 1,4 NAPHTHOQUINONE; 2 (5 N,N DIMETHYLHYDRAZONOFUR 2 YL) 5 METHOXY 1,4 BENZOQUINONE; 2 CHLORO 1,4 NAPHTHOQUINONE; 2 METHOXY 1,4 BENZOQUINONE; 3 CHLORO 2 (5 FORMYLFUR 2 YL) 1,4 NAPHTHOQUINONE; 3 CHLORO 2 (5 N,N DIMETHYLHYDRAZONOFUR 2 YL) 1,4 NAPHTHOQUINONE; ADENOSINE TRIPHOSPHATE; CASPASE 3; FURYL 1,4 QUINONE DERIVATIVE; FURYLQUINONE DERIVATIVE; GLUTATHIONE; PARACETAMOL; QUINONE DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CYTOCHROME P450 2E1;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SAFETY; ENZYME ACTIVITY; IN VITRO STUDY; LIPOPHILICITY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; ANIMAL; CANCER TRANSPLANTATION; CELL SURVIVAL; CHEMISTRY; COMPUTER PROGRAM; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; LIVER; LIVER TUMOR; METABOLISM; PATHOLOGY; PROTEIN SYNTHESIS; TUMOR CELL LINE; WISTAR RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROME P-450 CYP2E1; DRUG SCREENING ASSAYS, ANTITUMOR; GLUTATHIONE; LIVER; LIVER NEOPLASMS; MALE; MICE; NEOPLASM TRANSPLANTATION; PROTEIN BIOSYNTHESIS; QUINONES; RATS; RATS, WISTAR; SOFTWARE;

EID: 84856073385     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-010-9419-1     Document Type: Article

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