Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO

Investigational New Drugs

Volumn 29, Issue 5, 2011, Pages 719-729

  Hutchens, Steven ^a   Manevich, Yefim ^a   He, Lin ^a   Tew, Kenneth D ^a   Townsend, Danyelle M ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Glutathione; Glutathione S transferase; Nitric oxide; Nitrosative stress; Oxidative stress; Unfolded protein response

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; GLUTATHIONE TRANSFERASE; NITRIC OXIDE; OXYGEN [2,4 DINITRO 5 [4 (N METHYLAMINO)BENZOYLOXY]PHENYL] 1 (N,N DIMETHYLAMINO)DIAZEN 1 IUM 1,2 DIOLATE; PRODRUG; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 4 AMINOBENZOIC ACID; AZO COMPOUND; DRUG DERIVATIVE; GLUTATHIONE; O(2) (2,4 DINITRO 5 (N METHYL N 4 CARBOXYPHENYLAMINO)PHENYL 1 N,N DIMETHYLAMINO)DIAZEN 1 IUM 1,2 DIOLATE; O(2)-(2,4-DINITRO-5-(N-METHYL-N-4-CARBOXYPHENYLAMINO)PHENYL 1-N,N-DIMETHYLAMINO)DIAZEN-1-IUM-1,2-DIOLATE;

ANTIBIOTIC RESISTANCE; ARTICLE; CELL DENSITY; CELL DIFFERENTIATION; CELL GROWTH; CELL MEMBRANE RESISTANCE; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NITROSATIVE STRESS; NITROSYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN SECRETION; PROTEIN STRUCTURE; UNFOLDED PROTEIN RESPONSE; WILD TYPE; CELL DEATH; CELL PROLIFERATION; CELL SHAPE; CELL STRAIN HL 60; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; DRUG RESISTANCE; GENETICS; METABOLISM; SECRETION;

4-AMINOBENZOIC ACID; AZO COMPOUNDS; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HL-60 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; NITRIC OXIDE; PRODRUGS; UNFOLDED PROTEIN RESPONSE;

EID: 84856067661     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-010-9407-5     Document Type: Article

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