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Volumn 88, Issue 1036, 2012, Pages 79-87

Age-related cerebral white matter disease (Leukoaraiosis): A review

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; HOMOCYSTEINE;

EID: 84856021257     PISSN: 00325473     EISSN: 14690756     Source Type: Journal    
DOI: 10.1136/postgradmedj-2011-130307     Document Type: Article
Times cited : (148)

References (90)
  • 1
    • 77955360281 scopus 로고    scopus 로고
    • The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: Systematic review and meta-analysis
    • Debette S, Markus HS. The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ 2010; 341: c3666.
    • (2010) BMJ , vol.341
    • Debette, S.1    Markus, H.S.2
  • 2
    • 0001057279 scopus 로고
    • Die Abgrenzung der allgemeinen progressiven Paralyse
    • Binswanger O. Die Abgrenzung der allgemeinen progressiven Paralyse. Berl Klin Wochenschr 1894; 31: 1180-6.
    • (1894) Berl Klin Wochenschr , vol.31 , pp. 1180-1186
    • Binswanger, O.1
  • 3
    • 0000530314 scopus 로고
    • Die Seelenstörung auf arteriosklerotischer Grundlage
    • Alzheimer A. Die Seelenstörung auf arteriosklerotischer Grundlage. Allg Z Psychiat 1902; 59: 695-701.
    • (1902) Allg Z Psychiat , vol.59 , pp. 695-701
    • Alzheimer, A.1
  • 5
    • 77953026083 scopus 로고    scopus 로고
    • Vascular pathology in the aged human brain
    • Grinberg LT, Thal DR. Vascular pathology in the aged human brain. Acta Neuropathol 2010; 119: 277-90.
    • (2010) Acta Neuropathol , vol.119 , pp. 277-290
    • Grinberg, L.T.1    Thal, D.R.2
  • 6
    • 64549160555 scopus 로고    scopus 로고
    • Endothelial dysfunction in lacunar stroke: A systematic review
    • Knottnerus ILH, Ten Cate H, Lodder J, et al. Endothelial dysfunction in lacunar stroke: a systematic review. Cerebrovasc Dis 2009; 27: 519-26.
    • (2009) Cerebrovasc Dis , vol.27 , pp. 519-526
    • Knottnerus, I.L.H.1    Ten, C.H.2    Lodder, J.3
  • 7
    • 77953148668 scopus 로고    scopus 로고
    • A systematic review of dynamic cerebral and peripheral endothelial function in lacunar stroke versus controls
    • Stevenson SF, Doubal FN, Shuler K, et al. A systematic review of dynamic cerebral and peripheral endothelial function in lacunar stroke versus controls. Stroke 2010; 41: 434-42.
    • (2010) Stroke , vol.41 , pp. 434-442
    • Stevenson, S.F.1    Doubal, F.N.2    Shuler, K.3
  • 8
    • 76549093011 scopus 로고    scopus 로고
    • Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis
    • Topakian R, Barrick TR, Howe FA, et al. Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis. J Neurol Neurosurg Psychiatry 2010; 81: 192-7.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 192-197
    • Topakian, R.1    Barrick, T.R.2    Howe, F.A.3
  • 9
    • 70349673124 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells and age-related white matter changes
    • Jickling G, Salam A, Mohammad A, et al. Circulating endothelial progenitor cells and age-related white matter changes. Stroke 2009; 40: 3191-6.
    • (2009) Stroke , vol.40 , pp. 3191-3196
    • Jickling, G.1    Salam, A.2    Mohammad, A.3
  • 10
    • 63049124965 scopus 로고    scopus 로고
    • Association between cytokines and cerebral MRI changes in the aging brain
    • Baune BT, Ponath G, Rothermundt M, et al. Association between cytokines and cerebral MRI changes in the aging brain. J Geriatr Psychiatry Neurol 2009; 22: 23-34.
    • (2009) J Geriatr Psychiatry Neurol , vol.22 , pp. 23-34
    • Baune, B.T.1    Ponath, G.2    Rothermundt, M.3
  • 11
    • 62549145764 scopus 로고    scopus 로고
    • Lacunar stroke is associated with diffuse blood-brain barrier dysfunction
    • Wardlaw JM, Doubal F, Armitage P, et al. Lacunar stroke is associated with diffuse blood-brain barrier dysfunction. Ann Neurol 2009; 65: 194-202.
    • (2009) Ann Neurol , vol.65 , pp. 194-202
    • Wardlaw, J.M.1    Doubal, F.2    Armitage, P.3
  • 12
    • 0030937940 scopus 로고    scopus 로고
    • Pathogenesis of leukoaraiosis: A review
    • Pantoni L, Garcia JH. Pathogenesis of leukoaraiosis: a review. Stroke 1997; 28: 652-9.
    • (1997) Stroke , vol.28 , pp. 652-659
    • Pantoni, L.1    Garcia, J.H.2
  • 13
    • 62949164562 scopus 로고    scopus 로고
    • Understanding white matter disease: Imaging-pathological correlations in vascular cognitive impairment
    • Black S, Gao F, Bilbao J. Understanding white matter disease: imaging-pathological correlations in vascular cognitive impairment. Stroke 2009; 40: S48-52.
    • (2009) Stroke , vol.40
    • Black, S.1    Gao, F.2    Bilbao, J.3
  • 14
    • 0027493807 scopus 로고
    • Pathologic correlates of incidental MRI white matter signal hyperintensities
    • Fazekas F, Kleinert R, Offenbacher H, et al. Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology 1993; 43: 1683-9.
    • (1993) Neurology , vol.43 , pp. 1683-1689
    • Fazekas, F.1    Kleinert, R.2    Offenbacher, H.3
  • 15
    • 33745148241 scopus 로고    scopus 로고
    • White matter lesions in an unselected cohort of the elderly: Molecular pathology suggests origin from chronic hypoperfusion injury
    • Fernando MS, Simpson JE, Matthews F, et al. White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury. Stroke 2006; 37: 1391-8.
    • (2006) Stroke , vol.37 , pp. 1391-1398
    • Fernando, M.S.1    Simpson, J.E.2    Matthews, F.3
  • 16
    • 0029018417 scopus 로고
    • The significance of cerebral white matter abnormalities 100 years after Binswanger's report. A review
    • Pantoni L, Garcia JH. The significance of cerebral white matter abnormalities 100 years after Binswanger's report. A review. Stroke 1995; 26: 1293-301.
    • (1995) Stroke , vol.26 , pp. 1293-1301
    • Pantoni, L.1    Garcia, J.H.2
  • 17
    • 0000950693 scopus 로고
    • Lacunar infarctsda review
    • Fisher CM. Lacunar infarctsda review. Cerebrovasc Dis 1991; 1: 311-20.
    • (1991) Cerebrovasc Dis , vol.1 , pp. 311-320
    • Fisher, C.M.1
  • 18
    • 34347273783 scopus 로고    scopus 로고
    • Risk factor profile of cerebral small vessel disease and its subtypes
    • Khan U, Porteous L, Hassan A, et al. Risk factor profile of cerebral small vessel disease and its subtypes. J Neurol Neurosurg Psychiatry 2007; 78: 702-6.
    • (2007) J Neurol Neurosurg Psychiatry , vol.78 , pp. 702-706
    • Khan, U.1    Porteous, L.2    Hassan, A.3
  • 19
    • 66149169523 scopus 로고    scopus 로고
    • Pathology & genetics. cerebrovascular diseases
    • In: Kalimo H, ed., Basel: ISN Neuropath Press
    • Lammie AG. Pathology & genetics. cerebrovascular diseases. In: Kalimo H, ed. Pathology & Genetics. Cerebrovascular Diseases. Basel: ISN Neuropath Press, 2005: 85-91.
    • (2005) Pathology & Genetics. Cerebrovascular Diseases , pp. 85-91
    • Lammie, A.G.1
  • 20
    • 58649115794 scopus 로고    scopus 로고
    • Cerebral microbleeds: A guide to detection and interpretation
    • Greenberg SM, Vernooij MW, Cordonnier C, et al. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol 2009; 8: 165-74.
    • (2009) Lancet Neurol , vol.8 , pp. 165-174
    • Greenberg, S.M.1    Vernooij, M.W.2    Cordonnier, C.3
  • 21
    • 0036219691 scopus 로고    scopus 로고
    • Hypertensive pontine microhemorrhage
    • Jeong JH, Yoon SJ, Kang SJ, et al. Hypertensive pontine microhemorrhage. Stroke 2002; 33: 925-9.
    • (2002) Stroke , vol.33 , pp. 925-929
    • Jeong, J.H.1    Yoon, S.J.2    Kang, S.J.3
  • 22
    • 9444268676 scopus 로고    scopus 로고
    • Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study
    • Longstreth WT Jr, Manolio TA, Arnold A, et al. Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study. Stroke 1996; 27: 1274-82.
    • (1996) Stroke , vol.27 , pp. 1274-1282
    • Longstreth Jr, W.T.1    Manolio, T.A.2    Arnold, A.3
  • 23
    • 0028352896 scopus 로고
    • Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study
    • Breteler MM, van Amerongen NM, van Swieten JC, et al. Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study. Stroke 1994; 25: 1109-15.
    • (1994) Stroke , vol.25 , pp. 1109-1115
    • Breteler, M.M.1    van Amerongen, N.M.2    van Swieten, J.C.3
  • 24
    • 70350699165 scopus 로고    scopus 로고
    • White matter lesions and lacunar infarcts are independently and differently associated with brain atrophy: The SMARTMR study
    • Appelman AP, Vincken KL, van der Graaf Y, et al. White matter lesions and lacunar infarcts are independently and differently associated with brain atrophy: the SMARTMR study. Cerebrovasc Dis 2010; 29: 28-35.
    • (2010) Cerebrovasc Dis , vol.29 , pp. 28-35
    • Appelman, A.P.1    Vincken, K.L.2    van der Graaf, Y.3
  • 25
    • 0034986196 scopus 로고    scopus 로고
    • A new rating scale for age-related white matter changes applicable to MRI and CT
    • Wahlund LO, Barkhof F, Fazekas F, et al. A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke 2001; 32: 1318-22.
    • (2001) Stroke , vol.32 , pp. 1318-1322
    • Wahlund, L.O.1    Barkhof, F.2    Fazekas, F.3
  • 26
    • 0036720730 scopus 로고    scopus 로고
    • Subcortical lacunar lesions: An MR imaging finding in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
    • van Den Boom R, Lesnik Oberstein SA, van Duinen SG, et al. Subcortical lacunar lesions: an MR imaging finding in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Radiology 2002; 224: 791-6.
    • (2002) Radiology , vol.224 , pp. 791-796
    • van den Boom, R.1    Lesnik, O.S.A.2    van Duinen, S.G.3
  • 27
    • 0035852975 scopus 로고    scopus 로고
    • MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL
    • O'Sullivan M, Jarosz JM, Martin RJ, et al. MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL. Neurology 2001; 56: 628-34.
    • (2001) Neurology , vol.56 , pp. 628-634
    • O'Sullivan, M.1    Jarosz, J.M.2    Martin, R.J.3
  • 29
    • 0031917923 scopus 로고    scopus 로고
    • White matter changes on CT and MRI: An overview of visual rating scales. European Task Force on Age-Related White Matter Changes
    • Scheltens P, Erkinjunti T, Leys D, et al. White matter changes on CT and MRI: an overview of visual rating scales. European Task Force on Age-Related White Matter Changes. Eur Neurol 1998; 39: 80-9.
    • (1998) Eur Neurol , vol.39 , pp. 80-89
    • Scheltens, P.1    Erkinjunti, T.2    Leys, D.3
  • 30
    • 33748463270 scopus 로고    scopus 로고
    • Prevalence of white matter hyperintensities in a young healthy population
    • Hopkins RO, Beck CJ, Burnett DL, et al. Prevalence of white matter hyperintensities in a young healthy population. J Neuroimaging 2006; 16: 243-51.
    • (2006) J Neuroimaging , vol.16 , pp. 243-251
    • Hopkins, R.O.1    Beck, C.J.2    Burnett, D.L.3
  • 31
    • 0035132684 scopus 로고    scopus 로고
    • Prevalence of cerebral white matter lesions in elderly people: A population based magnetic resonance imaging study. The Rotterdam Scan Study
    • de Leeuw FE, de Groot JC, Achten E, et al. Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry 2001; 70: 9-14.
    • (2001) J Neurol Neurosurg Psychiatry , vol.70 , pp. 9-14
    • de Leeuw, F.E.1    de Groot, J.C.2    Achten, E.3
  • 32
    • 0031605089 scopus 로고    scopus 로고
    • Brain abnormalities in the elderly: Frequency and predictors in the United States (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group
    • Longstreth WT Jr. Brain abnormalities in the elderly: frequency and predictors in the United States (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group. J Neural Transm Suppl 1998; 53: 9-16.
    • (1998) J Neural Transm Suppl , vol.53 , pp. 9-16
    • Longstreth Jr, W.T.1
  • 33
    • 0035836741 scopus 로고    scopus 로고
    • Longitudinal study of blood pressure and white matter hyperintensities: The EVA MRI Cohort
    • Dufouil C, de Kersaint-Gilly A, Besancon V, et al. Longitudinal study of blood pressure and white matter hyperintensities: the EVA MRI Cohort. Neurology 2001; 56: 921-6.
    • (2001) Neurology , vol.56 , pp. 921-926
    • Dufouil, C.1    de Kersaint-Gilly, A.2    Besancon, V.3
  • 34
    • 0028108104 scopus 로고
    • Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: The Rotterdam Study
    • Breteler MM, van Swieten JC, Bots ML, et al. Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study. Neurology 1994; 44: 1246-52.
    • (1994) Neurology , vol.44 , pp. 1246-1252
    • Breteler, M.M.1    van Swieten, J.C.2    Bots, M.L.3
  • 35
    • 44449119902 scopus 로고    scopus 로고
    • Silent cerebral microbleeds on susceptibility-weighted imaging of patients with ischemic stroke and leukoaraiosis
    • Gao T, Wang Y, Zhang Z. Silent cerebral microbleeds on susceptibility-weighted imaging of patients with ischemic stroke and leukoaraiosis. Neurol Res 2008; 30: 272-6.
    • (2008) Neurol Res , vol.30 , pp. 272-276
    • Gao, T.1    Wang, Y.2    Zhang, Z.3
  • 36
    • 34548445857 scopus 로고    scopus 로고
    • Significant association between leukoaraiosis and metabolic syndrome in healthy subjects
    • Park K, Yasuda N, Toyonaga S, et al. Significant association between leukoaraiosis and metabolic syndrome in healthy subjects. Neurology 2007; 69: 974-8.
    • (2007) Neurology , vol.69 , pp. 974-978
    • Park, K.1    Yasuda, N.2    Toyonaga, S.3
  • 37
    • 1542409920 scopus 로고    scopus 로고
    • Explaining the decline in coronary heart disease mortality in England and Wales between 1981 and 2000
    • Unal B, Critchley JA, Capewell S. Explaining the decline in coronary heart disease mortality in England and Wales between 1981 and 2000. Circulation 2004; 109: 1101-7.
    • (2004) Circulation , vol.109 , pp. 1101-1107
    • Unal, B.1    Critchley, J.A.2    Capewell, S.3
  • 38
    • 34248324434 scopus 로고    scopus 로고
    • Change in incidence and aetiology of intracerebral haemorrhage in Oxfordshire, UK, between 1981 and 2006: A populationbased study
    • Lovelock CE, Molyneux AJ, Rothwell PM. Change in incidence and aetiology of intracerebral haemorrhage in Oxfordshire, UK, between 1981 and 2006: a populationbased study. Lancet Neurol 2007; 6: 487-93.
    • (2007) Lancet Neurol , vol.6 , pp. 487-493
    • Lovelock, C.E.1    Molyneux, A.J.2    Rothwell, P.M.3
  • 39
    • 8044244824 scopus 로고    scopus 로고
    • Correlates of leukoaraiosis and ventricular enlargement on magnetic resonance imaging: A study in normal elderly and cerebrovascular patients
    • Padovani A, Di Piero V, Bragoni M, et al. Correlates of leukoaraiosis and ventricular enlargement on magnetic resonance imaging: a study in normal elderly and cerebrovascular patients. Eur J Neurol 1997; 4: 15-23.
    • (1997) Eur J Neurol , vol.4 , pp. 15-23
    • Padovani, A.1    di Piero, V.2    Bragoni, M.3
  • 40
    • 0028893284 scopus 로고
    • Lack of relationship between leukoaraiosis and carotid artery disease. The North American Symptomatic Carotid Endarterectomy Trial
    • Streifler JY, Eliasziw M, Benavente OR, et al. Lack of relationship between leukoaraiosis and carotid artery disease. The North American Symptomatic Carotid Endarterectomy Trial. Arch Neurol 1995; 52: 21-4.
    • (1995) Arch Neurol , vol.52 , pp. 21-24
    • Streifler, J.Y.1    Eliasziw, M.2    Benavente, O.R.3
  • 41
    • 60549112211 scopus 로고    scopus 로고
    • Cerebral white matter lesions, gait, and the risk of incident falls: A prospective population-based study
    • Srikanth V, Beare R, Blizzard L, et al. Cerebral white matter lesions, gait, and the risk of incident falls: a prospective population-based study. Stroke 2009; 40: 175-80.
    • (2009) Stroke , vol.40 , pp. 175-180
    • Srikanth, V.1    Beare, R.2    Blizzard, L.3
  • 42
    • 54049142899 scopus 로고    scopus 로고
    • Progression of cerebral small vessel disease in relation to risk factors and cognitive consequences: Rotterdam Scan study
    • van Dijk EJ, Prins ND, Vrooman HA, et al. Progression of cerebral small vessel disease in relation to risk factors and cognitive consequences: Rotterdam Scan study. Stroke 2008; 39: 2712-19.
    • (2008) Stroke , vol.39 , pp. 2712-2719
    • van Dijk, E.J.1    Prins, N.D.2    Vrooman, H.A.3
  • 43
    • 84856013533 scopus 로고    scopus 로고
    • Validity of CT versus MR brain imaging in studies of risk factors for Leukoaraiosis: A systematic review
    • Simoni M, Mehta Z, Rothwell PM. Validity of CT versus MR brain imaging in studies of risk factors for Leukoaraiosis: a systematic review. Cerebrovasc Dis 2010; 29(Suppl 2): 300.
    • (2010) Cerebrovasc Dis , vol.29 , Issue.SUPPL. 2 , pp. 300
    • Simoni, M.1    Mehta, Z.2    Rothwell, P.M.3
  • 44
    • 74049088608 scopus 로고    scopus 로고
    • Blood pressure and white-matter disease progression in a biethnic cohort: Atherosclerosis Risk in Communities (ARIC) study
    • Gottesman RF, Coresh J, Catellier DJ, et al. Blood pressure and white-matter disease progression in a biethnic cohort: Atherosclerosis Risk in Communities (ARIC) study. Stroke 2010; 41: 3-8.
    • (2010) Stroke , vol.41 , pp. 3-8
    • Gottesman, R.F.1    Coresh, J.2    Catellier, D.J.3
  • 45
    • 70549106493 scopus 로고    scopus 로고
    • Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: Insights from the reduction of atherothrombosis for continued health (REACH) registry
    • Meadows TA, Bhatt DL, Hirsch AT, et al. Ethnic differences in the prevalence and treatment of cardiovascular risk factors in US outpatients with peripheral arterial disease: insights from the reduction of atherothrombosis for continued health (REACH) registry. Am Heart J 2009; 158: 1038-45.
    • (2009) Am Heart J , vol.158 , pp. 1038-1045
    • Meadows, T.A.1    Bhatt, D.L.2    Hirsch, A.T.3
  • 46
    • 70349662032 scopus 로고    scopus 로고
    • Cerebrovascular reactivity and dynamic autoregulation in ischaemic subcortical white matter disease
    • Birns J, Jarosz J, Markus HS, et al. Cerebrovascular reactivity and dynamic autoregulation in ischaemic subcortical white matter disease. J Neurol Neurosurg Psychiatry 2009; 80: 1093-8.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 1093-1098
    • Birns, J.1    Jarosz, J.2    Markus, H.S.3
  • 47
    • 44449156820 scopus 로고    scopus 로고
    • Metabolic syndrome is associated with silent ischemic brain lesions
    • Bokura H, Yamaguchi S, Iijima K, et al. Metabolic syndrome is associated with silent ischemic brain lesions. Stroke 2008; 39: 1607-9.
    • (2008) Stroke , vol.39 , pp. 1607-1609
    • Bokura, H.1    Yamaguchi, S.2    Iijima, K.3
  • 48
    • 63849083592 scopus 로고    scopus 로고
    • Visceral fat accumulation is a significant risk factor for white matter lesions in Japanese type 2 diabetic patients
    • Anan F, Masaki T, Eto T, et al. Visceral fat accumulation is a significant risk factor for white matter lesions in Japanese type 2 diabetic patients. Eur J Clin Invest 2009; 39: 368-74.
    • (2009) Eur J Clin Invest , vol.39 , pp. 368-374
    • Anan, F.1    Masaki, T.2    Eto, T.3
  • 49
    • 0023259350 scopus 로고
    • Leukoencephalopathy in patients with ischemic stroke
    • Bogousslavsky J, Regli F, Uske A. Leukoencephalopathy in patients with ischemic stroke. Stroke 1987; 18: 896-9.
    • (1987) Stroke , vol.18 , pp. 896-899
    • Bogousslavsky, J.1    Regli, F.2    Uske, A.3
  • 50
    • 28844461786 scopus 로고    scopus 로고
    • Heart failure with low cardiac output and risk of development of lesions in the cerebral white matter
    • Koçer A, Esen O, Ince N, et al. Heart failure with low cardiac output and risk of development of lesions in the cerebral white matter. Eur Gen Med 2005; 2: 56-61.
    • (2005) Eur Gen Med , vol.2 , pp. 56-61
    • Koçer, A.1    Esen, O.2    Ince, N.3
  • 51
    • 40149087509 scopus 로고    scopus 로고
    • Association between arterial stiffness and cerebral white matter lesions in community-dwelling elderly subjects
    • Ohmine T, Miwa Y, Yao H, et al. Association between arterial stiffness and cerebral white matter lesions in community-dwelling elderly subjects. Hypertens Res 2008; 31: 75-81.
    • (2008) Hypertens Res , vol.31 , pp. 75-81
    • Ohmine, T.1    Miwa, Y.2    Yao, H.3
  • 52
    • 0032966835 scopus 로고    scopus 로고
    • Relationships of cerebral MRI findings to ultrasonographic carotid atherosclerosis in older adults: The Cardiovascular Health Study. CHS Collaborative Research Group
    • Manolio TA, Burke GL, O'Leary DH, et al. Relationships of cerebral MRI findings to ultrasonographic carotid atherosclerosis in older adults: the Cardiovascular Health Study. CHS Collaborative Research Group. Arterioscler Thromb Vasc Biol 1999; 19: 356-65.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 356-365
    • Manolio, T.A.1    Burke, G.L.2    O'Leary, D.H.3
  • 53
    • 44449089581 scopus 로고    scopus 로고
    • Unrecognized myocardial infarction in relation to risk of dementia and cerebral small vessel disease
    • Ikram MA, van Oijen M, de Jong FJ, et al. Unrecognized myocardial infarction in relation to risk of dementia and cerebral small vessel disease. Stroke 2008; 39: 1421-6.
    • (2008) Stroke , vol.39 , pp. 1421-1426
    • Ikram, M.A.1    van Oijen, M.2    de Jong, F.J.3
  • 54
    • 0028255888 scopus 로고
    • Cerebral lesions on magnetic resonance imaging, heart disease, and vascular risk factors in subjects without stroke. A population-based study
    • Lindgren A, Roijer A, Rudling O, et al. Cerebral lesions on magnetic resonance imaging, heart disease, and vascular risk factors in subjects without stroke. A population-based study. Stroke 1994; 25: 929-34.
    • (1994) Stroke , vol.25 , pp. 929-934
    • Lindgren, A.1    Roijer, A.2    Rudling, O.3
  • 55
    • 60249089069 scopus 로고    scopus 로고
    • Plasma vitamin B12 status and cerebral white-matter lesions
    • de Lau LM, Smith AD, Refsum H, et al. Plasma vitamin B12 status and cerebral white-matter lesions. J Neurol Neurosurg Psychiatry 2009; 80: 149-57.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 149-157
    • de Lau, L.M.1    Smith, A.D.2    Refsum, H.3
  • 56
    • 65549138399 scopus 로고    scopus 로고
    • Periventricular white matter lucencies relate to low vitamin B12 levels in patients with small vessel stroke
    • Pieters B, Staals J, Knottnerus I, et al. Periventricular white matter lucencies relate to low vitamin B12 levels in patients with small vessel stroke. Stroke 2009; 40: 1623-6.
    • (2009) Stroke , vol.40 , pp. 1623-1626
    • Pieters, B.1    Staals, J.2    Knottnerus, I.3
  • 57
    • 20444410004 scopus 로고    scopus 로고
    • Total homocysteine is associated with white matter hyperintensity volume: The Northern Manhattan Study
    • Wright CB, Paik MC, Brown TR, et al. Total homocysteine is associated with white matter hyperintensity volume: the Northern Manhattan Study. Stroke 2005; 36: 1207-11.
    • (2005) Stroke , vol.36 , pp. 1207-1211
    • Wright, C.B.1    Paik, M.C.2    Brown, T.R.3
  • 58
    • 0346097879 scopus 로고    scopus 로고
    • Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction
    • Hassan A, Hunt BJ, O'Sullivan M, et al. Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction. Brain 2004; 127: 212-19.
    • (2004) Brain , vol.127 , pp. 212-219
    • Hassan, A.1    Hunt, B.J.2    O'Sullivan, M.3
  • 59
    • 0031778072 scopus 로고    scopus 로고
    • Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins
    • Carmelli D, DeCarli C, Swan GE, et al. Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins. Stroke 1998; 29: 1177-81.
    • (1998) Stroke , vol.29 , pp. 1177-1181
    • Carmelli, D.1    Decarli, C.2    Swan, G.E.3
  • 60
    • 0842289489 scopus 로고    scopus 로고
    • Heritability of leukoaraiosis in hypertensive sibships
    • Turner ST, Jack CR, Fornage M, et al. Heritability of leukoaraiosis in hypertensive sibships. Hypertension 2004; 43: 483-7.
    • (2004) Hypertension , vol.43 , pp. 483-487
    • Turner, S.T.1    Jack, C.R.2    Fornage, M.3
  • 61
    • 79960121999 scopus 로고    scopus 로고
    • White matter hyperintensities and cognition: Testing the reserve hypothesis
    • Brickman AM, Siedlecki KL, Muraskin J, et al. White matter hyperintensities and cognition: testing the reserve hypothesis. Neurobiol Aging 2011; 32: 1588-98.
    • (2011) Neurobiol Aging , vol.32 , pp. 1588-1598
    • Brickman, A.M.1    Siedlecki, K.L.2    Muraskin, J.3
  • 62
    • 61649123570 scopus 로고    scopus 로고
    • Longitudinal cognitive decline in subcortical ischemic vascular diseasedthe LADIS Study
    • Jokinen H, Kalska H, Ylikoski R, et al. Longitudinal cognitive decline in subcortical ischemic vascular diseasedthe LADIS Study. Cerebrovasc Dis 2009; 27: 384-91.
    • (2009) Cerebrovasc Dis , vol.27 , pp. 384-391
    • Jokinen, H.1    Kalska, H.2    Ylikoski, R.3
  • 64
    • 77952421448 scopus 로고    scopus 로고
    • Relationship between baseline whitematter changes and development of late-life depressive symptoms: 3-year results from the LADIS study
    • Teodorczuk A, Firbank MJ, Pantoni L, et al. Relationship between baseline whitematter changes and development of late-life depressive symptoms: 3-year results from the LADIS study. Psychol Med 2010; 40: 603-10.
    • (2010) Psychol Med , vol.40 , pp. 603-610
    • Teodorczuk, A.1    Firbank, M.J.2    Pantoni, L.3
  • 65
    • 41149085551 scopus 로고    scopus 로고
    • Association of gait and balance disorders with age-related white matter changes: The LADIS study
    • Baezner H, Blahak C, Poggesi A, et al. Association of gait and balance disorders with age-related white matter changes: the LADIS study. Neurology 2008; 70: 935-42.
    • (2008) Neurology , vol.70 , pp. 935-942
    • Baezner, H.1    Blahak, C.2    Poggesi, A.3
  • 66
    • 34249853210 scopus 로고    scopus 로고
    • Progression of cerebral white matter lesionsdclinical and radiological considerations
    • Enzinger C, Fazekas F, Ropele S, et al. Progression of cerebral white matter lesionsdclinical and radiological considerations. J Neurol Sci 2007; 257: 5-10.
    • (2007) J Neurol Sci , vol.257 , pp. 5-10
    • Enzinger, C.1    Fazekas, F.2    Ropele, S.3
  • 67
    • 23844520271 scopus 로고    scopus 로고
    • The association between white matter lesions, stroke and activities of daily livingdthe MEMO study on the KORA platform Augsburg
    • Berger K, Roesler A, Kretzschmar K. The association between white matter lesions, stroke and activities of daily livingdthe MEMO study on the KORA platform Augsburg. Gesundheitswesen 2005; (67 Suppl 1): S172-5.
    • (2005) Gesundheitswesen , vol.67 , Issue.SUPPL. 1
    • Berger, K.1    Roesler, A.2    Kretzschmar, K.3
  • 68
    • 20444422592 scopus 로고    scopus 로고
    • Extent of white matter lesions is related to acute subcortical infarcts and predicts further stroke risk in patients with first ever ischaemic stroke
    • Fu JH, Lu CZ, Hong Z, et al. Extent of white matter lesions is related to acute subcortical infarcts and predicts further stroke risk in patients with first ever ischaemic stroke. J Neurol Neurosurg Psychiatry 2005; 76: 793-6.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 793-796
    • Fu, J.H.1    Lu, C.Z.2    Hong, Z.3
  • 69
    • 0033551540 scopus 로고    scopus 로고
    • MRI white matter hyperintensities: Threeyear follow-up of the Austrian Stroke Prevention Study
    • Schmidt R, Fazekas F, Kapeller P, et al. MRI white matter hyperintensities: threeyear follow-up of the Austrian Stroke Prevention Study. Neurology 1999; 53: 132-9.
    • (1999) Neurology , vol.53 , pp. 132-139
    • Schmidt, R.1    Fazekas, F.2    Kapeller, P.3
  • 70
    • 0042845941 scopus 로고    scopus 로고
    • Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: Correlation with vascular risk factors
    • Taylor WD, MacFall JR, Provenzale JM, et al. Serial MR imaging of volumes of hyperintense white matter lesions in elderly patients: correlation with vascular risk factors. Am J Roentgenol 2003; 181: 571-6.
    • (2003) Am J Roentgenol , vol.181 , pp. 571-576
    • Taylor, W.D.1    Macfall, J.R.2    Provenzale, J.M.3
  • 71
    • 23844437999 scopus 로고    scopus 로고
    • C-reactive protein and cerebral smallvessel disease: The Rotterdam Scan Study
    • van Dijk EJ, Prins ND, Vermeer SE, et al. C-reactive protein and cerebral smallvessel disease: the Rotterdam Scan Study. Circulation 2005; 112: 900-5.
    • (2005) Circulation , vol.112 , pp. 900-905
    • van Dijk, E.J.1    Prins, N.D.2    Vermeer, S.E.3
  • 72
    • 11144223888 scopus 로고    scopus 로고
    • Incidence, manifestations, and predictors of worsening white matter on serial cranial magnetic resonance imaging in the elderly: The Cardiovascular Health Study
    • Longstreth WT Jr, Arnold AM, Beauchamp NJ Jr, et al. Incidence, manifestations, and predictors of worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study. Stroke 2005; 36: 56-61.
    • (2005) Stroke , vol.36 , pp. 56-61
    • Longstreth Jr, W.T.1    Arnold, A.M.2    Beauchamp Jr, N.J.3
  • 73
    • 44449143042 scopus 로고    scopus 로고
    • Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: The Leukoaraiosis and Disability Study
    • Gouw AA, van der Flier WM, Fazekas F, et al. Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: The Leukoaraiosis and Disability Study. Stroke 2008; 39: 1414-20.
    • (2008) Stroke , vol.39 , pp. 1414-1420
    • Gouw, A.A.1    van der Flier, W.M.2    Fazekas, F.3
  • 74
    • 0026703561 scopus 로고
    • White-matter hyperintensity and neuropsychological functions in dementia and healthy aging
    • Almkvist O, Wahlund LO, Andersson-Lundman G, et al. White-matter hyperintensity and neuropsychological functions in dementia and healthy aging. Arch Neurol 1992; 49: 626-32.
    • (1992) Arch Neurol , vol.49 , pp. 626-632
    • Almkvist, O.1    Wahlund, L.O.2    Andersson-Lundman, G.3
  • 75
    • 0037383825 scopus 로고    scopus 로고
    • Prognostic significance of white matter changes in a memory clinic population
    • Bronge L, Wahlund LO. Prognostic significance of white matter changes in a memory clinic population. Psychiatry Res 2003; 122: 199-206.
    • (2003) Psychiatry Res , vol.122 , pp. 199-206
    • Bronge, L.1    Wahlund, L.O.2
  • 76
    • 0027724463 scopus 로고
    • Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: A longitudinal study
    • Bracco L, Campani D, Baratti E, et al. Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: a longitudinal study. J Neurol Sci 1993; 120: 131-6.
    • (1993) J Neurol Sci , vol.120 , pp. 131-136
    • Bracco, L.1    Campani, D.2    Baratti, E.3
  • 77
    • 0037111136 scopus 로고    scopus 로고
    • The natural course of MRI white matter hyperintensities
    • Schmidt R, Schmidt H, Kapeller P, et al. The natural course of MRI white matter hyperintensities. J Neurol Sci 2002; 203-204: 253-7.
    • (2002) J Neurol Sci , vol.203-204 , pp. 253-257
    • Schmidt, R.1    Schmidt, H.2    Kapeller, P.3
  • 78
    • 0035949762 scopus 로고    scopus 로고
    • A prospective study of cerebral white matter abnormalities in older people with gait dysfunction
    • Whitman GT, Tang Y, Lin A, et al. A prospective study of cerebral white matter abnormalities in older people with gait dysfunction. Neurology 2001; 57: 990-4.
    • (2001) Neurology , vol.57 , pp. 990-994
    • Whitman, G.T.1    Tang, Y.2    Lin, A.3
  • 79
    • 33746332960 scopus 로고    scopus 로고
    • Cerebral white matter hyperintensities on MRI: Current concepts and therapeutic implications
    • Ovbiagele B, Saver JL. Cerebral white matter hyperintensities on MRI: current concepts and therapeutic implications. Cerebrovasc Dis 2006; 22: 83-90.
    • (2006) Cerebrovasc Dis , vol.22 , pp. 83-90
    • Ovbiagele, B.1    Saver, J.L.2
  • 80
    • 24944486283 scopus 로고    scopus 로고
    • Effects of blood pressure lowering on cerebral white matter hyperintensities in patients with stroke: The PROGRESS (Perindopril Protection Against Recurrent Stroke Study) Magnetic Resonance Imaging Substudy
    • Dufouil C, Chalmers J, Coskun O, et al. Effects of blood pressure lowering on cerebral white matter hyperintensities in patients with stroke: the PROGRESS (Perindopril Protection Against Recurrent Stroke Study) Magnetic Resonance Imaging Substudy. Circulation 2005; 13: 1644-50.
    • (2005) Circulation , vol.13 , pp. 1644-1650
    • Dufouil, C.1    Chalmers, J.2    Coskun, O.3
  • 81
    • 18844415380 scopus 로고    scopus 로고
    • Effect of pravastatin on cerebral infarcts and white matter lesions
    • ten Dam VH, van den Heuvel DM, van Buchem MA, et al. Effect of pravastatin on cerebral infarcts and white matter lesions. Neurology 2005; 64: 1807-9.
    • (2005) Neurology , vol.64 , pp. 1807-1809
    • Ten, D.V.H.1    van den Heuvel, D.M.2    van Buchem, M.A.3
  • 82
    • 0038048903 scopus 로고    scopus 로고
    • Are cholesterol-lowering medications and antihypertensive agents preventing stroke in ways other than by controlling the risk factor?
    • Ruland S, Gorelick PB. Are cholesterol-lowering medications and antihypertensive agents preventing stroke in ways other than by controlling the risk factor? Curr Atheroscler Rep 2003; 5: 38-43.
    • (2003) Curr Atheroscler Rep , vol.5 , pp. 38-43
    • Ruland, S.1    Gorelick, P.B.2
  • 83
    • 67349124996 scopus 로고    scopus 로고
    • Effects of statins on the progression of cerebral white matter lesion: Post hoc analysis of the ROCAS (Regression of Cerebral Artery Stenosis) study
    • Mok VC, Lam WW, Fan YH, et al. Effects of statins on the progression of cerebral white matter lesion: post hoc analysis of the ROCAS (Regression of Cerebral Artery Stenosis) study. J Neurol 2009; 256: 750-7.
    • (2009) J Neurol , vol.256 , pp. 750-757
    • Mok, V.C.1    Lam, W.W.2    Fan, Y.H.3
  • 84
    • 0037335810 scopus 로고    scopus 로고
    • Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: In vitro and in vivo/ex vivo studies
    • Aktas B, Utz A, Hoenig-Liedl P, et al. Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies. Stroke 2003; 34: 764-9.
    • (2003) Stroke , vol.34 , pp. 764-769
    • Aktas, B.1    Utz, A.2    Hoenig-Liedl, P.3
  • 85
    • 0036284867 scopus 로고    scopus 로고
    • Silent cerebral microbleeds on T2*- weighted MRI: Correlation with stroke subtype, stroke recurrence, and leukoaraiosis
    • Kato H, Izumiyama M, Izumiyama K, et al. Silent cerebral microbleeds on T2*- weighted MRI: correlation with stroke subtype, stroke recurrence, and leukoaraiosis. Stroke 2002; 33: 1536-40.
    • (2002) Stroke , vol.33 , pp. 1536-1540
    • Kato, H.1    Izumiyama, M.2    Izumiyama, K.3
  • 86
    • 31744438360 scopus 로고    scopus 로고
    • Effects of microbleeds on hemorrhage development in leukoaraiosis patients
    • Lee SH, Heo JH, Yoon BW. Effects of microbleeds on hemorrhage development in leukoaraiosis patients. Hypertens Res 2005; 28: 895-9.
    • (2005) Hypertens Res , vol.28 , pp. 895-899
    • Lee, S.H.1    Heo, J.H.2    Yoon, B.W.3
  • 87
    • 34147124515 scopus 로고    scopus 로고
    • Leukoaraiosis and intracerebral hemorrhage after thrombolysis in acute stroke
    • Palumbo V, Boulanger JM, Hill MD, et al. Leukoaraiosis and intracerebral hemorrhage after thrombolysis in acute stroke. Neurology 2007; 68: 1020-4.
    • (2007) Neurology , vol.68 , pp. 1020-1024
    • Palumbo, V.1    Boulanger, J.M.2    Hill, M.D.3
  • 88
    • 33748317511 scopus 로고    scopus 로고
    • Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke
    • Neumann-Haefelin T, Hoelig S, Berkefeld J, et al. Leukoaraiosis is a risk factor for symptomatic intracerebral hemorrhage after thrombolysis for acute stroke. Stroke 2006; 37: 2463-6.
    • (2006) Stroke , vol.37 , pp. 2463-2466
    • Neumann-Haefelin, T.1    Hoelig, S.2    Berkefeld, J.3
  • 89
    • 0032862352 scopus 로고    scopus 로고
    • Major bleeding during anticoagulation after cerebral ischemia: Patterns and risk factors
    • for the Stroke Prevention in Reversible Ischemia Trial (SPIRIT) and European Atrial Fibrillation Trial (EAFT) Study Groups
    • Gorter JW; for the Stroke Prevention in Reversible Ischemia Trial (SPIRIT) and European Atrial Fibrillation Trial (EAFT) Study Groups. Major bleeding during anticoagulation after cerebral ischemia: patterns and risk factors. Neurology 1999; 53: 1319-27.
    • (1999) Neurology , vol.53 , pp. 1319-1327
    • Gorter, J.W.1
  • 90
    • 0037162371 scopus 로고    scopus 로고
    • Leukoaraiosis is associated with warfarinrelated hemorrhage following ischemic stroke: The Cardiovascular Health Study
    • Smith EE, Rosand J, Knudsen BA, et al. Leukoaraiosis is associated with warfarinrelated hemorrhage following ischemic stroke: the Cardiovascular Health Study. Neurology 2002; 59: 193-7.
    • (2002) Neurology , vol.59 , pp. 193-197
    • Smith, E.E.1    Rosand, J.2    Knudsen, B.A.3


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