Synthesis of pyrazolo[3,4-b]pyridines under microwave irradiation in multi-component reactions and their antitumor and antimicrobial activities - Part 1

European Journal of Medicinal Chemistry

Volumn 48, Issue , 2012, Pages 92-96

  El Borai, M A ^a   Rizk, H F ^a   Abd Aal, M F ^a   El Deeb, I Y ^a  

^a Tanta University   (Egypt)

Author keywords

Antimicrobial activities; Antitumor activities; Microwave irradiation; Multi component reactions; Pyrazolo 3,4 b pyridine

Indexed keywords

1,4 DIPHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 6 CARBOXYLIC ACID; 4 (3,4 DIMETHOXYPHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 6 CARBOXYLIC ACID; 4 (4 BROMOPHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 6 CARBOXYLIC ACID; 4 (4 HYDROXYPHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 6 CARBOXYLIC ACID; 4 (4 METHOXYPHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 6 CARBOXYLIC ACID; 4 (4 METHOXYPHENYL) 1 PHENYL 3,6 BIS (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 5 CARBONITRILE; 4 (4 METHOXYPHENYL) 1,6 DIPHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 5 CARBONITRILE; 4 (4 METHOXYPHENYL) 6 (4 NITROPHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 5 CARBONITRILE; 4 [4 (DIETHYLAMINO)PHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 6 CARBOXYLIC ACID; 4 [4 (DIMETHYLAMINO)PHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 6 CARBOXYLIC ACID; 6 (4 CHLOROPHENYL) 4 (4 METHOXYPHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 5 CARBONITRILE; 6 (4 FLUOROPHENYL) 4 (4 METHOXYPHENYL) 1 PHENYL 3 (PYRIDIN 3 YL) 1H PYRAZOLO[3,4 B]PYRIDINE 5 CARBONITRILE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CHLORAMPHENICOL; DOXORUBICIN; PYRAZOLO[3,4 B]PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CHEMICAL REACTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; FUSARIUM OXYSPORUM; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HEATING; LIVER CANCER; MICROWAVE IRRADIATION; MULTI COMPONENT SYSTEM; ONE POT SYNTHESIS; PENICILLIUM EXPANSUM; SERRATIA;

ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; INHIBITORY CONCENTRATION 50; LIVER NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; MICROWAVES; MOLECULAR STRUCTURE; PYRAZOLES; PYRIDINES; SPECTROPHOTOMETRY, INFRARED;

EID: 84856007823     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.11.038     Document Type: Article

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