Candida albicans Dicer (CaDcr1) is required for efficient ribosomal and spliceosomal RNA maturation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 2, 2012, Pages 523-528

  Bernstein, Douglas A ^a   Vyas, Valmik K ^a   Weinberg, David E ^a,b   Drinnenberg, Ines A ^a,b   Bartel, David P ^a,b   Fink, Gerald R ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Argonaute; Bifunctional dicer; CDL1

Indexed keywords

CANDIDA ALBICANS DICER 1; DICER; FUNGAL ENZYME; RIBONUCLEASE III; SMALL INTERFERING RNA; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA ALBICANS; GENE DELETION; GENE REPRESSION; GENE SILENCING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RNA CLEAVAGE; RNA INTERFERENCE; RNA PROCESSING; SACCHAROMYCES; SACCHAROMYCES CASTELLII; SPLICEOSOME;

CANDIDA ALBICANS; EVOLUTION, MOLECULAR; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, FUNGAL; MODELS, GENETIC; PHYLOGENY; RIBONUCLEASE III; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; RNA, RIBOSOMAL; SPLICEOSOMES; SYNTENY;

CANDIDA ALBICANS; SACCHAROMYCES CASTELLII; SACCHAROMYCETALES;

EID: 84856005348     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118859109     Document Type: Article

References (38)

1. Venema J, Tollervey D (1999) Ribosome synthesis in Saccharomyces cerevisiae. Annu Rev Genet 33:261-311. (Pubitemid 30083125)
2. Black DL (2003) Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem 72:291-336.
3. Phizicky EM, Hopper AK (2010) tRNA biology charges to the front. Genes Dev 24: 1832-1860.
4. Meister G, Tuschl T (2004) Mechanisms of gene silencing by double-stranded RNA. Nature 431:343-349. (Pubitemid 39265674)
5. Zamore PD, Haley B (2005) Ribo-gnome: The big world of small RNAs. Science 309: 1519-1524. (Pubitemid 41266468)
6. Ding SW, Voinnet O (2007) Antiviral immunity directed by small RNAs. Cell 130: 413-426.
7. Malone CD, Hannon GJ (2009) Small RNAs as guardians of the genome. Cell 136: 656-668.
8. Nakayashiki H, Kadotani N, Mayama S (2006) Evolution and diversification of RNA silencing proteins in fungi. J Mol Evol 63:127-135. (Pubitemid 43992011)
9. Hall TM (2005) Structure and function of argonaute proteins. Structure 13:1403-1408.
10. Czech B, Hannon GJ (2011) Small RNA sorting: Matchmaking for Argonautes. Nat Rev Genet 12:19-31.
11. Drinnenberg IA, et al. (2009) RNAi in budding yeast. Science 326:544-550.
12. Staab JF, White TC, Marr KA (2011) Hairpin dsRNA does not trigger RNA interference in Candida albicans cells. Yeast 28:1-8.
13. Nowotny M, Yang W (2009) Structural and functional modules in RNA interference. Curr Opin Struct Biol 19:286-293.
14. MacRae IJ, Doudna JA (2007) Ribonuclease revisited: Structural insights into ribonuclease III family enzymes. Curr Opin Struct Biol 17:138-145. (Pubitemid 46240810)
15. MacRae IJ, Zhou K, Doudna JA (2007) Structural determinants of RNA recognition and cleavage by Dicer. Nat Struct Mol Biol 14:934-940. (Pubitemid 47525174)
16. Weinberg DE, Nakanishi K, Patel DJ, Bartel DP (2011) The inside-out mechanism of Dicers from budding yeasts. Cell 146:262-276.
17. Abou Elela S, Ares M, Jr. (1998) Depletion of yeast RNase III blocks correct U2 3′ end formation and results in polyadenylated but functional U2 snRNA. EMBO J 17: 3738-3746.
18. Lamontagne B, Larose S, Boulanger J, Elela SA (2001) The RNase III family: A conserved structure and expanding functions in eukaryotic dsRNA metabolism. Curr Issues Mol Biol 3:71-78. (Pubitemid 33061770)
19. Chanfreau G, Elela SA, Ares M, Jr., Guthrie C (1997) Alternative 3′-end processing of U5 snRNA by RNase III. Genes Dev 11:2741-2751. (Pubitemid 27452396)
20. Elela SA, Igel H, Ares M, Jr. (1996) RNase III cleaves eukaryotic preribosomal RNA at a U3 snoRNP-dependent site. Cell 85:115-124. (Pubitemid 26116812)
21. Chanfreau G, Legrain P, Jacquier A (1998) Yeast RNase III as a key processing enzyme in small nucleolar RNAs metabolism. J Mol Biol 284:975-988. (Pubitemid 28558550)
22. Provost P, et al. (2002) Dicer is required for chromosome segregation and gene silencing in fission yeast cells. Proc Natl Acad Sci USA 99:16648-16653. (Pubitemid 36034027)
23. Wang X, et al. (2010) Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi. Genes Dev 24:2566-2582.
24. Allmang C, et al. (1999) Functions of the exosome in rRNA, snoRNA and snRNA synthesis. EMBO J 18:5399-5410. (Pubitemid 29465589)
25. Iino Y, Sugimoto A, Yamamoto M (1991) S. pombe pac1+, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase. EMBO J 10:221-226. (Pubitemid 21905285)
26. Xu HP, Riggs M, Rodgers L, Wigler M (1990) A gene from S. pombe with homology to E. coli RNAse III blocks conjugation and sporulation when overexpressed in wild type cells. Nucleic Acids Res 18:5304. (Pubitemid 20270103)
27. Drinnenberg IA, Fink GR, Bartel DP (2011) Compatibility with killer explains the rise of RNAi-deficient fungi. Science 333:1592.
28. Goodwin TJ, Ormandy JE, Poulter RT (2001) L1-like non-LTR retrotransposons in the yeast Candida albicans. Curr Genet 39:83-91. (Pubitemid 32422017)
29. Pils B, Schultz J (2004) Inactive enzyme-homologues find new function in regulatory processes. J Mol Biol 340:399-404. (Pubitemid 38797988)
30. Marchler-Bauer A, et al. (2011) CDD: A Conserved Domain Database for the functional annotation of proteins. Nucleic Acids Res 39(Database issue):D225-D229.
31. Subramaniam S (1998) The Biology Workbench - a seamless database and analysis environment for the biologist. Proteins 32:1-2.
32. Page RD (1996) TreeView: An application to display phylogenetic trees on personal computers. Comput Appl Biosci 12:357-358.
33. Byrne KP, Wolfe KH (2005) The Yeast Gene Order Browser: Combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15: 1456-1461. (Pubitemid 41400914)
34. Fitzpatrick DA, O'Gaora P, Byrne KP, Butler G (2010) Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser. BMC Genomics 11:290.
35. Gillum AM, Tsay EY, Kirsch DR (1984) Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol Gen Genet 198:179-182. (Pubitemid 15180998)
36. Fonzi WA, Irwin MY (1993) Isogenic strain construction and gene mapping in Candida albicans. Genetics 134:717-728. (Pubitemid 23193572)
37. Wilson RB, Davis D, Mitchell AP (1999) Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions. J Bacteriol 181:1868-1874. (Pubitemid 29138620)
38. Shen J, Cowen LE, Griffin AM, Chan L, Köhler JR (2008) The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation. Proc Natl Acad Sci USA 105:20918-20923.