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Volumn 25, Issue 1, 2012, Pages 3-15

Gastrointestinal hormones: The regulation of appetite and the anorexia of ageing

Author keywords

Appetite; Elderly; Gut hormones; Malnutrition

Indexed keywords

GASTROINTESTINAL HORMONE;

EID: 84855996119     PISSN: 09523871     EISSN: 1365277X     Source Type: Journal    
DOI: 10.1111/j.1365-277X.2011.01211.x     Document Type: Review
Times cited : (66)

References (94)
  • 1
    • 0028232363 scopus 로고
    • Undernutrition in the nursing home: prevalence, consequences, causes and prevention
    • Abbasi, A.A. & Rudman, D. (1994) Undernutrition in the nursing home: prevalence, consequences, causes and prevention. Nutr. Rev. 52, 113-122.
    • (1994) Nutr. Rev. , vol.52 , pp. 113-122
    • Abbasi, A.A.1    Rudman, D.2
  • 5
    • 0032814858 scopus 로고    scopus 로고
    • Comparison of the postprandial release of peptide YY and proglucagon-derived peptides in the rat
    • Anini, Y., Fu-Cheng, X., Cuber, J.C., Kervran, A., Chariot, J. & Roz, C. (1999) Comparison of the postprandial release of peptide YY and proglucagon-derived peptides in the rat. Pflugers Arch. 438, 299-306.
    • (1999) Pflugers Arch. , vol.438 , pp. 299-306
    • Anini, Y.1    Fu-Cheng, X.2    Cuber, J.C.3    Kervran, A.4    Chariot, J.5    Roz, C.6
  • 7
    • 46349108886 scopus 로고    scopus 로고
    • Efficacy of ghrelin as a therapeutic approach for age-related physiological changes
    • Ariyasu, H., Iwakura, H., Yamada, G., Nakao, K., Kangawa, K. & Akamizu, T. (2008) Efficacy of ghrelin as a therapeutic approach for age-related physiological changes. Endocrinology 149, 3722-3728.
    • (2008) Endocrinology , vol.149 , pp. 3722-3728
    • Ariyasu, H.1    Iwakura, H.2    Yamada, G.3    Nakao, K.4    Kangawa, K.5    Akamizu, T.6
  • 9
    • 0034611681 scopus 로고    scopus 로고
    • Genetics of body-weight regulation
    • Barsh, G.S., Farooqi, I.S. & O'Rahilly, S. (2000) Genetics of body-weight regulation. Nature 404, 644-651.
    • (2000) Nature , vol.404 , pp. 644-651
    • Barsh, G.S.1    Farooqi, I.S.2    O'Rahilly, S.3
  • 10
    • 0019867175 scopus 로고
    • [Bioactive 'enteroglucagon' (oxyntomodulin): evidence for a C-terminal extension of the glucagon molecule]
    • Bataille, D., Tatemoto, K., Coudray, A.M., Rosselin, G. & Mutt, V. (1981) [Bioactive 'enteroglucagon' (oxyntomodulin): evidence for a C-terminal extension of the glucagon molecule]. C. R. Seances Acad. Sci. III 293, 323-328.
    • (1981) C. R. Seances Acad. Sci. III , vol.293 , pp. 323-328
    • Bataille, D.1    Tatemoto, K.2    Coudray, A.M.3    Rosselin, G.4    Mutt, V.5
  • 16
    • 0026632294 scopus 로고
    • Correlation between echographic gastric emptying and appetite: influence of psyllium
    • Bergmann, J.F., Chassany, O., Petit, A., Triki, R., Caulin, C. & Segrestaa, J.M. (1992) Correlation between echographic gastric emptying and appetite: influence of psyllium. Gut 33, 1042-1043.
    • (1992) Gut , vol.33 , pp. 1042-1043
    • Bergmann, J.F.1    Chassany, O.2    Petit, A.3    Triki, R.4    Caulin, C.5    Segrestaa, J.M.6
  • 17
    • 55049123496 scopus 로고    scopus 로고
    • The clinical significance of gastrointestinal changes with aging
    • Bhutto, A. & Morley, J.E. (2008) The clinical significance of gastrointestinal changes with aging. Curr. Opin. Clin. Nutr. Metab Care 11, 651-660.
    • (2008) Curr. Opin. Clin. Nutr. Metab Care , vol.11 , pp. 651-660
    • Bhutto, A.1    Morley, J.E.2
  • 19
    • 33845448933 scopus 로고    scopus 로고
    • Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice
    • Brown, L.M., Clegg, D.J., Benoit, S.C. & Woods, S.C. (2006) Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice. Physiol. Behav. 89, 687-691.
    • (2006) Physiol. Behav. , vol.89 , pp. 687-691
    • Brown, L.M.1    Clegg, D.J.2    Benoit, S.C.3    Woods, S.C.4
  • 20
    • 0037207472 scopus 로고    scopus 로고
    • Blood glucose dynamics and control of meal initiation: a pattern detection and recognition theory
    • Campfield, L.A. & Smith, F.J. (2003) Blood glucose dynamics and control of meal initiation: a pattern detection and recognition theory. Physiol. Rev. 83, 25-58.
    • (2003) Physiol. Rev. , vol.83 , pp. 25-58
    • Campfield, L.A.1    Smith, F.J.2
  • 21
  • 23
    • 0028838246 scopus 로고
    • Body fatness and waist circumference are independent predictors of the age-associated increase in fasting insulin levels in healthy men and women
    • Colman, E., Toth, M.J., Katzel, L.I., Fonong, T., Gardner, A.W. & Poehlman, E.T. (1995) Body fatness and waist circumference are independent predictors of the age-associated increase in fasting insulin levels in healthy men and women. Int. J. Obes. Relat. Metab. Disord. 19, 798-803.
    • (1995) Int. J. Obes. Relat. Metab. Disord. , vol.19 , pp. 798-803
    • Colman, E.1    Toth, M.J.2    Katzel, L.I.3    Fonong, T.4    Gardner, A.W.5    Poehlman, E.T.6
  • 24
    • 0034046021 scopus 로고    scopus 로고
    • Protein-energy undernutrition in hospital in-patients
    • Corish, C.A. & Kennedy, N.P. (2000) Protein-energy undernutrition in hospital in-patients. Br. J. Nutr. 83, 575-591.
    • (2000) Br. J. Nutr. , vol.83 , pp. 575-591
    • Corish, C.A.1    Kennedy, N.P.2
  • 25
    • 33846574365 scopus 로고    scopus 로고
    • Peptide YY: a neuroendocrine neighbor of note
    • Cox, H.M. (2007) Peptide YY: a neuroendocrine neighbor of note. Peptides 28, 345-351.
    • (2007) Peptides , vol.28 , pp. 345-351
    • Cox, H.M.1
  • 26
    • 0028300692 scopus 로고
    • Biological actions of cholecystokinin
    • Crawley, J.N. & Corwin, R.L. (1994) Biological actions of cholecystokinin. Peptides 15, 731-755.
    • (1994) Peptides , vol.15 , pp. 731-755
    • Crawley, J.N.1    Corwin, R.L.2
  • 27
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings, D.E., Purnell, J.Q., Frayo, R.S., Schmidova, K., Wisse, B.E. & Weigle, D.S. (2001) A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 50, 1714-1719.
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3    Schmidova, K.4    Wisse, B.E.5    Weigle, D.S.6
  • 28
    • 0034993576 scopus 로고    scopus 로고
    • An underfeeding study in healthy men and women provides further evidence of impaired regulation of energy expenditure in old age
    • Das, S.K., Moriguti, J.C., McCrory, M.A., Saltzman, E., Mosunic, C., Greenberg, A.S. & Roberts, S.B. (2001) An underfeeding study in healthy men and women provides further evidence of impaired regulation of energy expenditure in old age. J. Nutr. 131, 1833-1838.
    • (2001) J. Nutr. , vol.131 , pp. 1833-1838
    • Das, S.K.1    Moriguti, J.C.2    McCrory, M.A.3    Saltzman, E.4    Mosunic, C.5    Greenberg, A.S.6    Roberts, S.B.7
  • 29
    • 0033679897 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
    • Date, Y., Kojima, M., Hosoda, H., Sawaguchi, A., Mondal, M.S., Suganuma, T., Matsukura, S., Kangawa, K. & Nakazato, M. (2000) Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 141, 4255-4261.
    • (2000) Endocrinology , vol.141 , pp. 4255-4261
    • Date, Y.1    Kojima, M.2    Hosoda, H.3    Sawaguchi, A.4    Mondal, M.S.5    Suganuma, T.6    Matsukura, S.7    Kangawa, K.8    Nakazato, M.9
  • 30
    • 0027769484 scopus 로고
    • Age-related changes in spontaneous food intake and hunger in humans
    • De Castro, J.M. (1993) Age-related changes in spontaneous food intake and hunger in humans. Appetite 21, 255-272.
    • (1993) Appetite , vol.21 , pp. 255-272
    • De Castro, J.M.1
  • 31
    • 31344480672 scopus 로고    scopus 로고
    • Delayed postprandial gastric emptying and impaired gallbladder contraction together with elevated cholecystokinin and peptide YY serum levels sustain satiety and inhibit hunger in healthy elderly persons
    • Di Francesco, V., Zamboni, M., Dioli, A., Zoico, E., Mazzali, G., Omizzolo, F., Bissoli, L., Solerte, S.B., Benini, L. & Bosello, O. (2005) Delayed postprandial gastric emptying and impaired gallbladder contraction together with elevated cholecystokinin and peptide YY serum levels sustain satiety and inhibit hunger in healthy elderly persons. J. Gerontol. A Biol. Sci. Med. Sci. 60, 1581-1585.
    • (2005) J. Gerontol. A Biol. Sci. Med. Sci. , vol.60 , pp. 1581-1585
    • Di Francesco, V.1    Zamboni, M.2    Dioli, A.3    Zoico, E.4    Mazzali, G.5    Omizzolo, F.6    Bissoli, L.7    Solerte, S.B.8    Benini, L.9    Bosello, O.10
  • 34
    • 0034534361 scopus 로고    scopus 로고
    • Fasting insulin levels influence plasma leptin levels independently from the contribution of adiposity: evidence from both a cross-sectional and an intervention study
    • Doucet, E., St-Pierre, S., Almeras, N., Mauriege, P., Despres, J.P., Richard, D., Bouchard, C. & Tremblay, A. (2000) Fasting insulin levels influence plasma leptin levels independently from the contribution of adiposity: evidence from both a cross-sectional and an intervention study. J. Clin. Endocrinol. Metab. 85, 4231-4237.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 4231-4237
    • Doucet, E.1    St-Pierre, S.2    Almeras, N.3    Mauriege, P.4    Despres, J.P.5    Richard, D.6    Bouchard, C.7    Tremblay, A.8
  • 35
    • 0027510652 scopus 로고
    • Assessing nutritional status in elderly patients
    • Dwyer, J.T., Gallo, J.J. & Reichel, W. (1993) Assessing nutritional status in elderly patients. Am. Fam. Physician 47, 613-620.
    • (1993) Am. Fam. Physician , vol.47 , pp. 613-620
    • Dwyer, J.T.1    Gallo, J.J.2    Reichel, W.3
  • 36
    • 84856008383 scopus 로고    scopus 로고
    • pound;13 billion cost of malnutrition must be tackled. BAPEN Press Release.
    • Elia, M. (2009) £13 billion cost of malnutrition must be tackled. BAPEN Press Release.
    • (2009)
    • Elia, M.1
  • 37
    • 84856014238 scopus 로고    scopus 로고
    • Combatting malnutrition: recommendation for action. A report from the advisory group on malnutrition, led by BAPEN. 42. Redditch: BAPEN.
    • Elia, M. & Russell, C.A. (2009) Combatting malnutrition: recommendation for action. A report from the advisory group on malnutrition, led by BAPEN. 42. Redditch: BAPEN.
    • (2009)
    • Elia, M.1    Russell, C.A.2
  • 38
    • 64849087970 scopus 로고    scopus 로고
    • Megestrol acetate and mirtazapine for the treatment of unplanned weight loss in the elderly
    • Fox, C.B., Treadway, A.K., Blaszczyk, A.T. & Sleeper, R.B. (2009) Megestrol acetate and mirtazapine for the treatment of unplanned weight loss in the elderly. Pharmacotherapy 29, 383-397.
    • (2009) Pharmacotherapy , vol.29 , pp. 383-397
    • Fox, C.B.1    Treadway, A.K.2    Blaszczyk, A.T.3    Sleeper, R.B.4
  • 39
    • 0023131391 scopus 로고
    • Age-related changes in postprandial plasma glucose, insulin, and free fatty acid concentrations in nondiabetic individuals
    • Fraze, E., Chiou, Y.A., Chen, Y.D. & Reaven, G.M. (1987) Age-related changes in postprandial plasma glucose, insulin, and free fatty acid concentrations in nondiabetic individuals. J. Am. Geriatr. Soc. 35, 224-228.
    • (1987) J. Am. Geriatr. Soc. , vol.35 , pp. 224-228
    • Fraze, E.1    Chiou, Y.A.2    Chen, Y.D.3    Reaven, G.M.4
  • 42
    • 57549094457 scopus 로고    scopus 로고
    • Gut hormones and appetite control
    • Hameed, S., Dhillo, W.S. & Bloom, S.R. (2009) Gut hormones and appetite control. Oral Dis. 15, 18-26.
    • (2009) Oral Dis. , vol.15 , pp. 18-26
    • Hameed, S.1    Dhillo, W.S.2    Bloom, S.R.3
  • 43
    • 33845594753 scopus 로고    scopus 로고
    • Aging with quality of life - a challenge for society
    • Hauser, G. & Neumann, M. (2005) Aging with quality of life - a challenge for society. J. Physiol. Pharmacol. 56(Suppl 2), 35-48.
    • (2005) J. Physiol. Pharmacol. , vol.56 , Issue.SUPPL. 2 , pp. 35-48
    • Hauser, G.1    Neumann, M.2
  • 44
    • 1242274640 scopus 로고    scopus 로고
    • Does additional feeding support provided by health care assistants improve nutritional status and outcome in acutely ill older in-patients? - a randomised control trial
    • Hickson, M., Bulpitt, C., Nunes, M., Peters, R., Cooke, J., Nicholl, C. & Frost, G. (2004) Does additional feeding support provided by health care assistants improve nutritional status and outcome in acutely ill older in-patients? - a randomised control trial Clin. Nutr. 23, 69-77.
    • (2004) Clin. Nutr. , vol.23 , pp. 69-77
    • Hickson, M.1    Bulpitt, C.2    Nunes, M.3    Peters, R.4    Cooke, J.5    Nicholl, C.6    Frost, G.7
  • 45
    • 0021828051 scopus 로고
    • Comparative study of the effects of equal amounts of fat, protein, and starch on plasma cholecystokinin in man
    • Hopman, W.P., Jansen, J.B. & Lamers, C.B. (1985) Comparative study of the effects of equal amounts of fat, protein, and starch on plasma cholecystokinin in man. Scand. J. Gastroenterol. 20, 843-847.
    • (1985) Scand. J. Gastroenterol. , vol.20 , pp. 843-847
    • Hopman, W.P.1    Jansen, J.B.2    Lamers, C.B.3
  • 47
    • 0036307610 scopus 로고    scopus 로고
    • The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects
    • Hui, H., Farilla, L., Merkel, P. & Perfetti, R. (2002) The short half-life of glucagon-like peptide-1 in plasma does not reflect its long-lasting beneficial effects. Eur. J. Endocrinol. 146, 863-869.
    • (2002) Eur. J. Endocrinol. , vol.146 , pp. 863-869
    • Hui, H.1    Farilla, L.2    Merkel, P.3    Perfetti, R.4
  • 48
    • 70450209446 scopus 로고    scopus 로고
    • The Malnutrition Screening Tool is a useful tool for identifying malnutrition risk in residential aged care
    • Isenring, E.A., Bauer, J.D., Banks, M. & Gaskill, D. (2009) The Malnutrition Screening Tool is a useful tool for identifying malnutrition risk in residential aged care. J. Hum. Nutr. Diet. 22, 545-550.
    • (2009) J. Hum. Nutr. Diet. , vol.22 , pp. 545-550
    • Isenring, E.A.1    Bauer, J.D.2    Banks, M.3    Gaskill, D.4
  • 49
    • 34147157240 scopus 로고    scopus 로고
    • Acylated ghrelin secretion is acutely suppressed by oral glucose load or insulin-induced hypoglycemia independently of basal growth hormone secretion in humans
    • Kim, S.W., Kim, K.W., Shin, C.S., Park, d.J., Park, K.S., Cho, B.Y., Lee, H.K. & Kim, S.Y. (2007) Acylated ghrelin secretion is acutely suppressed by oral glucose load or insulin-induced hypoglycemia independently of basal growth hormone secretion in humans. Horm. Res. 67, 211-219.
    • (2007) Horm. Res. , vol.67 , pp. 211-219
    • Kim, S.W.1    Kim, K.W.2    Shin, C.S.3    Park, dJ.4    Park, K.S.5    Cho, B.Y.6    Lee, H.K.7    Kim, S.Y.8
  • 50
    • 0030833813 scopus 로고    scopus 로고
    • Effects of exercise on appetite control: implications for energy balance
    • King, N.A., Tremblay, A. & Blundell, J.E. (1997) Effects of exercise on appetite control: implications for energy balance. Med. Sci. Sports Exerc. 29, 1076-1089.
    • (1997) Med. Sci. Sports Exerc. , vol.29 , pp. 1076-1089
    • King, N.A.1    Tremblay, A.2    Blundell, J.E.3
  • 51
    • 0019381381 scopus 로고
    • C-terminal octapeptide of cholecystokinin decreases food intake in man
    • Kissileff, H.R., Pi-Sunyer, F.X., Thornton, J. & Smith, G.P. (1981) C-terminal octapeptide of cholecystokinin decreases food intake in man. Am. J. Clin. Nutr. 34, 154-160.
    • (1981) Am. J. Clin. Nutr. , vol.34 , pp. 154-160
    • Kissileff, H.R.1    Pi-Sunyer, F.X.2    Thornton, J.3    Smith, G.P.4
  • 52
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M., Hosoda, H., Date, Y., Nakazato, M., Matsuo, H. & Kangawa, K. (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 53
    • 0020364112 scopus 로고
    • Degradation of cholecystokinin octapeptide, related fragments and analogs by human and rat plasma in vitro
    • Koulischer, D., Moroder, L. & schodt-Lanckman, M. (1982) Degradation of cholecystokinin octapeptide, related fragments and analogs by human and rat plasma in vitro. Regul. Pept. 4, 127-139.
    • (1982) Regul. Pept. , vol.4 , pp. 127-139
    • Koulischer, D.1    Moroder, L.2    schodt-Lanckman, M.3
  • 54
    • 0018070788 scopus 로고
    • Distribution of gastrin and CCK cells in the rat gastrointestinal tract. Evidence for the occurrence of three distinct cell types storing COOH-terminal gastrin immunoreactivity
    • Larsson, L.I. & Rehfeld, J.F. (1978) Distribution of gastrin and CCK cells in the rat gastrointestinal tract. Evidence for the occurrence of three distinct cell types storing COOH-terminal gastrin immunoreactivity. Histochemistry 58, 23-31.
    • (1978) Histochemistry , vol.58 , pp. 23-31
    • Larsson, L.I.1    Rehfeld, J.F.2
  • 55
    • 0027533197 scopus 로고
    • Anorexia and weight loss as the solitary symptoms of choledocholithiasis
    • Lissoos, T.W., Hanan, I.M. & Blackstone, M.O. (1993) Anorexia and weight loss as the solitary symptoms of choledocholithiasis. South. Med. J. 86, 239-241.
    • (1993) South. Med. J. , vol.86 , pp. 239-241
    • Lissoos, T.W.1    Hanan, I.M.2    Blackstone, M.O.3
  • 57
    • 0019261015 scopus 로고
    • Glucagon precursors identified by immunoprecipitation of products of cell-free translation of messenger RNA
    • Lund, P.K., Goodman, R.H., Jacobs, J.W. & Habener, J.F. (1980) Glucagon precursors identified by immunoprecipitation of products of cell-free translation of messenger RNA. Diabetes 29, 583-586.
    • (1980) Diabetes , vol.29 , pp. 583-586
    • Lund, P.K.1    Goodman, R.H.2    Jacobs, J.W.3    Habener, J.F.4
  • 58
    • 0032915336 scopus 로고    scopus 로고
    • Effects of age on concentrations of plasma cholecystokinin, glucagon-like peptide 1, and peptide YY and their relation to appetite and pyloric motility
    • MacIntosh, C.G., Andrews, J.M., Jones, K.L., Wishart, J.M., Morris, H.A., Jansen, J.B., Morley, J.E., Horowitz, M. & Chapman, I.M. (1999) Effects of age on concentrations of plasma cholecystokinin, glucagon-like peptide 1, and peptide YY and their relation to appetite and pyloric motility. Am. J. Clin. Nutr. 69, 999-1006.
    • (1999) Am. J. Clin. Nutr. , vol.69 , pp. 999-1006
    • MacIntosh, C.G.1    Andrews, J.M.2    Jones, K.L.3    Wishart, J.M.4    Morris, H.A.5    Jansen, J.B.6    Morley, J.E.7    Horowitz, M.8    Chapman, I.M.9
  • 59
    • 0035051335 scopus 로고    scopus 로고
    • Effect of small intestinal nutrient infusion on appetite, gastrointestinal hormone release, and gastric myoelectrical activity in young and older men
    • MacIntosh, C.G., Horowitz, M., Verhagen, M.A., Smout, A.J., Wishart, J., Morris, H., Goble, E., Morley, J.E. & Chapman, I.M. (2001) Effect of small intestinal nutrient infusion on appetite, gastrointestinal hormone release, and gastric myoelectrical activity in young and older men. Am. J. Gastroenterol. 96, 997-1007.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 997-1007
    • MacIntosh, C.G.1    Horowitz, M.2    Verhagen, M.A.3    Smout, A.J.4    Wishart, J.5    Morris, H.6    Goble, E.7    Morley, J.E.8    Chapman, I.M.9
  • 61
    • 33644770419 scopus 로고    scopus 로고
    • Meta-analysis: protein and energy supplementation in older people
    • Milne, A.C., Avenell, A. & Potter, J. (2006) Meta-analysis: protein and energy supplementation in older people. Ann. Intern. Med. 144, 37-48.
    • (2006) Ann. Intern. Med. , vol.144 , pp. 37-48
    • Milne, A.C.1    Avenell, A.2    Potter, J.3
  • 62
    • 0020528254 scopus 로고
    • Effect of age on gastric emptying of liquid - solid meals in man
    • Moore, J.G., Tweedy, C., Christian, P.E. & Datz, F.L. (1983) Effect of age on gastric emptying of liquid - solid meals in man. Dig. Dis. Sci. 28, 340-344.
    • (1983) Dig. Dis. Sci. , vol.28 , pp. 340-344
    • Moore, J.G.1    Tweedy, C.2    Christian, P.E.3    Datz, F.L.4
  • 67
    • 20844460120 scopus 로고    scopus 로고
    • Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
    • Nagaya, N., Moriya, J., Yasumura, Y., Uematsu, M., Ono, F., Shimizu, W., Ueno, K., Kitakaze, M., Miyatake, K. & Kangawa, K. (2004) Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation 110, 3674-3679.
    • (2004) Circulation , vol.110 , pp. 3674-3679
    • Nagaya, N.1    Moriya, J.2    Yasumura, Y.3    Uematsu, M.4    Ono, F.5    Shimizu, W.6    Ueno, K.7    Kitakaze, M.8    Miyatake, K.9    Kangawa, K.10
  • 72
  • 73
    • 0023829632 scopus 로고
    • Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects
    • Polonsky, K.S., Given, B.D. & Van, C.E. (1988) Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J. Clin. Invest. 81, 442-448.
    • (1988) J. Clin. Invest. , vol.81 , pp. 442-448
    • Polonsky, K.S.1    Given, B.D.2    Van, C.E.3
  • 74
    • 0031030810 scopus 로고    scopus 로고
    • Helicobacter pylori infection and anorexia of aging
    • Portnoi, V.A. (1997) Helicobacter pylori infection and anorexia of aging. Arch. Intern. Med. 157, 269-272.
    • (1997) Arch. Intern. Med. , vol.157 , pp. 269-272
    • Portnoi, V.A.1
  • 77
    • 0036171253 scopus 로고    scopus 로고
    • Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract
    • Sakata, I., Nakamura, K., Yamazaki, M., Matsubara, M., Hayashi, Y., Kangawa, K. & Sakai, T. (2002) Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract. Peptides 23, 531-536.
    • (2002) Peptides , vol.23 , pp. 531-536
    • Sakata, I.1    Nakamura, K.2    Yamazaki, M.3    Matsubara, M.4    Hayashi, Y.5    Kangawa, K.6    Sakai, T.7
  • 78
    • 0032968622 scopus 로고    scopus 로고
    • Human rectal endocrine cells and aging
    • Sandstrom, O. & El-Salhy, M. (1999) Human rectal endocrine cells and aging. Mech. Ageing Dev. 108, 219-226.
    • (1999) Mech. Ageing Dev. , vol.108 , pp. 219-226
    • Sandstrom, O.1    El-Salhy, M.2
  • 79
    • 0023714388 scopus 로고
    • Oxyntomodulin: a potential hormone from the distal gut. Pharmacokinetics and effects on gastric acid and insulin secretion in man
    • Schjoldager, B.T., Baldissera, F.G., Mortensen, P.E., Holst, J.J. & Christiansen, J. (1988) Oxyntomodulin: a potential hormone from the distal gut. Pharmacokinetics and effects on gastric acid and insulin secretion in man. Eur. J. Clin. Invest. 18, 499-503.
    • (1988) Eur. J. Clin. Invest. , vol.18 , pp. 499-503
    • Schjoldager, B.T.1    Baldissera, F.G.2    Mortensen, P.E.3    Holst, J.J.4    Christiansen, J.5
  • 82
    • 65549149072 scopus 로고    scopus 로고
    • Effect of age and frailty on ghrelin and cholecystokinin responses to a meal test
    • Serra-Prat, M., Palomera, E., Clave, P. & Puig-Domingo, M. (2009) Effect of age and frailty on ghrelin and cholecystokinin responses to a meal test. Am. J. Clin. Nutr. 89, 1410-1417.
    • (2009) Am. J. Clin. Nutr. , vol.89 , pp. 1410-1417
    • Serra-Prat, M.1    Palomera, E.2    Clave, P.3    Puig-Domingo, M.4
  • 83
    • 0042384489 scopus 로고    scopus 로고
    • Appetite, food intake, and plasma concentrations of cholecystokinin, ghrelin, and other gastrointestinal hormones in undernourished older women and well-nourished young and older women
    • Sturm, K., MacIntosh, C.G., Parker, B.A., Wishart, J., Horowitz, M. & Chapman, I.M. (2003) Appetite, food intake, and plasma concentrations of cholecystokinin, ghrelin, and other gastrointestinal hormones in undernourished older women and well-nourished young and older women. J. Clin. Endocrinol. Metab. 88, 3747-3755.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 3747-3755
    • Sturm, K.1    MacIntosh, C.G.2    Parker, B.A.3    Wishart, J.4    Horowitz, M.5    Chapman, I.M.6
  • 85
    • 0029766931 scopus 로고    scopus 로고
    • Neuropeptide Y- and peptide YY-containing colonic cells increase with ageing in male rats
    • Sweet, M.A., Ntambi, J.A., Gaumnitz, E.A., Pugh, T.D., Weindruch, R. & Singaram, C. (1996) Neuropeptide Y- and peptide YY-containing colonic cells increase with ageing in male rats. Neuropeptides 30, 385-390.
    • (1996) Neuropeptides , vol.30 , pp. 385-390
    • Sweet, M.A.1    Ntambi, J.A.2    Gaumnitz, E.A.3    Pugh, T.D.4    Weindruch, R.5    Singaram, C.6
  • 86
    • 0019310264 scopus 로고
    • Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides
    • Tatemoto, K. & Mutt, V. (1980) Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides. Nature 285, 417-418.
    • (1980) Nature , vol.285 , pp. 417-418
    • Tatemoto, K.1    Mutt, V.2
  • 87
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop, M., Smiley, D.L. & Heiman, M.L. (2000) Ghrelin induces adiposity in rodents. Nature 407, 908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 89
    • 0033780811 scopus 로고    scopus 로고
    • Adiposity signals and the control of energy homeostasis
    • Woods, S.C. & Seeley, R.J. (2000) Adiposity signals and the control of energy homeostasis. Nutrition 16, 894-902.
    • (2000) Nutrition , vol.16 , pp. 894-902
    • Woods, S.C.1    Seeley, R.J.2
  • 93
    • 0024238973 scopus 로고
    • Calorie and nutrient intakes of elderly and young subjects measured under identical conditions
    • Wurtman, J.J., Lieberman, H., Tsay, R., Nader, T. & Chew, B. (1988) Calorie and nutrient intakes of elderly and young subjects measured under identical conditions. J. Gerontol. 43, B174-B180.
    • (1988) J. Gerontol. , vol.43
    • Wurtman, J.J.1    Lieberman, H.2    Tsay, R.3    Nader, T.4    Chew, B.5


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