Alpha-momorcharin possessing high immunogenicity, immunotoxicity and hepatotoxicity in SD rats

Journal of Ethnopharmacology

Volumn 139, Issue 2, 2012, Pages 590-598

  Meng, Yao ^a   Liu, Bin ^a   Lei, Ning ^b   Zheng, Juecun ^c   He, Qianchuan ^d   Li, Dan ^c   Zhao, Xiaojun ^a,e   Shen, Fubing ^c  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU UNIVERSITY OF TECHNOLOGY   (China)

^c CHENGDU MEDICAL COLLEGE   (China)

^d IL   (United States)

^e Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Momorcharin; General toxicity; Immunogenicity; Immunotoxicity; Ribosome inactivating protein

Indexed keywords

ALPHA MOMORCHARIN; IMMUNOGLOBULIN G; IMMUNOMODULATING AGENT; RIBOSOME INACTIVATING PROTEIN; UNCLASSIFIED DRUG;

ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; BLOOD CELL; BLOOD CHEMISTRY; BODY WEIGHT; BONE MARROW CELL; CELL DEATH; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CONVALESCENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GUINEA PIG; HISTOPATHOLOGY; IMMUNOGENICITY; IMMUNOTOXICITY; LIVER CELL; LIVER FUNCTION TEST; LIVER TOXICITY; MALE; MAXIMUM TOLERATED DOSE; MOMORDICA CHARANTIA; NONHUMAN; PLANT SEED; PROTEIN ISOLATION; PROTEIN PURIFICATION; RAT; TOXICITY TESTING;

ANAPHYLAXIS; ANIMALS; ANTIBODIES; BIOLOGICAL MARKERS; BIOPSY; BONE MARROW CELLS; BONE MARROW EXAMINATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GUINEA PIGS; LIVER; LIVER FUNCTION TESTS; MALE; MAXIMUM TOLERATED DOSE; MOMORDICA CHARANTIA; NECROSIS; PASSIVE CUTANEOUS ANAPHYLAXIS; PLANT EXTRACTS; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOME INACTIVATING PROTEINS; SEEDS; T-LYMPHOCYTE SUBSETS; TIME FACTORS; TOXICITY TESTS; WEIGHT LOSS;

ANIMALIA; CAVIA; CUCUMIS; CUCURBITACEAE; MOMORDICA; MOMORDICA CHARANTIA; RATTUS;

EID: 84855992495     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.11.057     Document Type: Article

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