Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum

Phytomedicine

Volumn 17, Issue 3-4, 2010, Pages 300-304

  Antonisamy, P ^a   Ignacimuthu, S ^a  

^a LOYOLA COLLEGE   (India)

Author keywords

Analgesic; Anti pyretic; Chromobacterium violaceum; Immunomodulatory; Violacein; Writhing response

Indexed keywords

ACETIC ACID; ANALGESIC AGENT; ANTIPYRETIC AGENT; DEXAMETHASONE; FORMALDEHYDE; IMMUNOMODULATING AGENT; INDOMETACIN; MORPHINE; NALOXONE; OVALBUMIN; UNCLASSIFIED DRUG; VIOLACEIN;

ANALGESIC ACTIVITY; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIPYRETIC ACTIVITY; ARTICLE; CHROMOBACTERIUM VIOLACEUM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; EDEMA; HINDLIMB; HOT PLATE TEST; HYPERPYREXIA; IMMUNOMODULATION; LICKING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SHEEP ERYTHROCYTE; WISTAR RAT; WRITHING TEST;

ACETIC ACID; ANALGESICS; ANAPHYLAXIS; ANIMALS; BEHAVIOR, ANIMAL; CHROMOBACTERIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; ERYTHROCYTES; FEMALE; FEVER; FORMALDEHYDE; HOT TEMPERATURE; HYPERSENSITIVITY; HYPERSENSITIVITY, DELAYED; IMMUNOLOGIC FACTORS; INDIA; INDOLES; INDOMETHACIN; MALE; MICE; OVALBUMIN; PAIN; RATS; RATS, WISTAR; SHEEP; YEASTS;

CHROMOBACTERIUM VIOLACEUM; MUS; NEGIBACTERIA; OVIS ARIES; RATTUS; RATTUS NORVEGICUS;

EID: 75249094065     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.05.018     Document Type: Article

References (32)

1. Adzu B., Amos S., Kapu S.D., and Gamaniel K.S. Anti-inflammatory and anti-nociceptive effects of Sphaeranthus senegalensis. J. Ethnopharmacol. 84 (2003) 169-173
2. Andrighetti-Frohner C.R., Antonio R.V., Creczynski-Pasa T.B., Barardi C.R.M., and Simoes C.M.O. Cytotoxicity and potential antiviral evaluation of violacein produced by Chromobacterium violaceum. Mem. Inst. Oswaldo Cruz Rio de Janeiro 98 (2003) 843-848
3. Antonisamy, P., Kannan, P., Ignacimuthu, S., 2009. Anti-diarrhoeal and ulcer protective effects of violacein isolated from Chromobacterium violaceum in wistar rats. Fund. & Clin. pharmacol. (in press).
4. Benencia F., Courreges M.C., and Coulombie F.C. In vivo and in vitro immunomodulatory activities of Trichilia glabra aqueous leaf extracts. J. Ethanopharmacol. 69 (2000) 199-205
5. Bromberg N., and Duran N. Violacein transformation by peroxidases and oxidases: implications on its biological properties. J. Mol. Catal. B: Enzyme 11 (2001) 463-467
6. Caldas L.R., Leitao A.A.C., Santos S.M., and Tyrrell R.M. Preliminary experiments on the photobiological properties of violacein. In: Tyrrell R.M. (Ed). Proceedings of the International Symposium on Current Topics in Radiology and Photobiology (1978), Academia Brasileira de Ciencias, Rio de Janeiro 121-126
7. Cappuccino J.G., and Sherman N. Microbiology: A Laboratory Manual. Pearson Education (2004), Singapore Pte. Ltd. pp. 137-185
8. Carvalho D.D., Costa F.T.M., Duran N., and Haun M. Cytotoxic activity of violacein in human colon cancer cells. Toxicol. In vitro 20 (2006) 1514-1521
9. Chattopadhyay A., Kumar V., Bhat N., and Rao P. Chromobacterium violaceum infection: a rare but frequently fatal disease. J. Pediatr. Surg. 37 (2002) 108-110
10. De Souza A.O., Aily D.C.G., Sato D.N., and Duran N. Atividade da violaceina in vitro sobre o Mycobacterium turbeculosis H37RA. Rev. Inst. Adolfo Lutz 58 (1999) 59-62
11. Duran, N., 1998. Formulation of cyclodextrin/violacein based medicine-comprises enhancement of violacein solubility, with increase in versatility. BR PI 9801307-A.
12. Duran N., Antonio R.V., Haun M., and Pilli R.A. Biosynthesis of a trypanocide by Chromobacterium violaceum. World J. Microbiol. Biotechnol. 10 (1994) 686-690
13. Duran N., Campos V., Riveros R., Joyas A., Pereira M.F., and Haun M. Bacterial chemistry: III. Preliminary studies on the trypanosomal activities of Chromobacterium violaceum products. An Acad. Bras. Cienc. 61 (1989) 31-36
14. Duran N., and Menck C.F.M. Chromobacterium violaceum: a review of pharmacological and industrial perspective. Crit. Rev. Microbiol. 27 (2001) 201-222
15. Ferreira C.V., Bos C.L., Versteeg H.H., Justo G.Z., Duran N., and Peppelenbosch M.P. Molecular mechanism of violacein-mediated human leukemia cell death. Blood 104 (2004) 1459-1464
16. Hao C., Zhang H., Has R., Bai Z., and Zhang B. A novel community of acidophiles in an acid mine drainage sediment. World J. Microbiol. Biotechnol. 23 (2007) 15-21
17. Hunskaar S., and Hole K. The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain 30 (1987) 103-114
18. Kodach L.L., Bos C.L., Duran N., Peppelenbosch M.P., Ferreira C.V., and Hardwick J.C.H. Violacein Synergistically Increases 5-Fluorouracil Cytotoxicity, Induces Apoptosis and Inhibits Akt-Mediated Signal Transduction in Human Colorectal Cancer Cells (2006), Oxford University Press
19. Konzen M., De Marco D., Cordova C.A.S., Vieira T.O., Antonio R.V., and Creczynski-Pasa T.B. Antioxidant properties of violacein: possible relation on its biological function. Bioorg. Med. Chem. 14 (2006) 8307-8313
20. Leon L.L., Miranda C.C., De Souza A.O., and Duran N. Antileishmanial activity of the violacein extracted from Chromobacterium violaceum. J. Antimicrob. Agents Chemother. 48 (2001) 449-450
21. Martinez I., Rorvik L.M., Brox V., Lassen J., Seppola M., Gram L., and Vogel F. Genetic variability among isolates of Listeria monocytogenes from food products, clinical samples and processing environments, estimated by RAPD typing. Int. J. Food Microbiol. 84 (2003) 285-297
22. May, G., Brummer, B., Ott, H., 1991. Treatment of prophylaxis of polio and herpes virus infections - comprises admin. of 3- (1, 2-dihydro-5-(5-hydroxy-1H- indol-3-yl)-2-oxo-3Hpyrrole- 3-ylidene)-1,3-dihydro-2H-indol-2-one. Ger Offen DE 3935066.
23. Melo P.S., Maria S.S., Vidal B.C., Haun M., and Duran N. Violacein cytotoxicity and induction of apoptosis in V79 cells. In vitro Cell Dev. Biol. Anim. 36 (2000) 539-543
24. Milton A.S. Prostaglandins and fever. Trends Pharmacol. Sci. 40 (1982) 490-492
25. Mungantiwar A.A., Nair A.M., Shinde U.A., Dikshit V.J., Saraf M.N., Thakur V.S., and Sainis *. Studies on the Immunomodulatory effects of Boerhaavia diffusa alkaloidal fraction. J. Ethanopharmacol. 65 (1999) 125-131
26. Parkhouse J., and Pleuvry B.J. Analgesic Drug (1979), Blackwell, Oxford pp. 1-5
27. Reisine T., and Pasternack G. Opioid analgesics and antagonists. In: Hardman J.G., and Limbird L.E. (Eds). Goodman and Gilman's, the Pharmacological Basis of Therapeutics. 9th ed (1996), McGraw-Hill, New York 521-526
28. Tallarida R.J., and Murria R.B. Manual of pharmacologic calculations with computer programs. second ed (1987), Springer-Verlag, New York pp. 110-134
29. Teotino U.M., Friz L.P., Ganduni A., and Bella D.D. Thio derivatives of 2, 3-dihydro-4H-1, 3-benzoazin-4-one, synthesis and pharmacological properties. J. Med. Chem. 6 (1963) 248-250
30. Vane J.R. The evolution of non-steroidal anti-inflammatory drugs and their mechanisms of action. Drugs 33 (1987) 18-27
31. Vasconcelos A.T.R., et al. The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability. Brazilian Nat. Genome Proj. Consortium 100 (2003) 11660-11665
32. Vogel H.G., and Vogel W.H. Drug Discovery and Evaluation, Pharmacological Assays (1997), Springer, Berlin pp. 402-403