Critical role of proinflammatory cytokine IL-6 in allograft rejection and tolerance

American Journal of Transplantation

Volumn 12, Issue 1, 2012, Pages 90-101

  Zhao, X ^a,b   Boenisch, O ^a   Yeung, M ^a   Mfarrej, B ^a   Yang, Sunmi ^a   Turka, L A ^c   Sayegh, M H ^a   Iacomini, J ^a   Yuan, X ^a,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

^d PEKING UNIVERSITY   (China)

Author keywords

Allograft tolerance; CD4; costimulation blockade; CTLA4Ig; IFN ; IL 17; IL 6; rejection; transplantation

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; IMMUNOGLOBULIN; INTERLEUKIN 6;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; LYMPHOCYTE PROLIFERATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REGULATORY T LYMPHOCYTE; TH1 CELL; TH2 CELL; UPREGULATION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GRAFT REJECTION; HEART TRANSPLANTATION; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL;

EID: 84855962311     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2011.03770.x     Document Type: Article

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