A vaccinia virus-driven interplay between the MKK4/7-JNK1/2 pathway and cytoskeleton reorganization

Journal of Virology

Volumn 86, Issue 1, 2012, Pages 172-184

  Pereira, Anna C T C ^a,e   Leite, Flávia G G ^a,f   Brasil, Bruno S A F ^a,g   Soares Martins, Jamaria A P ^b   Torres, Alice A ^a   Pimenta, Paulo F P ^c   Souto Padrón, Thaïs ^d   Traktman, Paula ^b   Ferreira, Paulo C P ^a   Kroon, Erna G ^a   Bonjardim, Cláudio A ^a  

^a Instituto de Ciências Biológicas   (Brazil)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

^d FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^e FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^f INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA   (Austria)

^g FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN 5; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE 7; PAXILLIN; STRESS ACTIVATED PROTEIN KINASE;

ACTIN FILAMENT; ARTICLE; CELL MIGRATION; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MICROTUBULE ORGANIZING CENTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VACCINIA VIRUS; VIRUS CELL INTERACTION; VIRUS REPLICATION;

ANIMALS; CELL MOVEMENT; CYTOSKELETON; HUMANS; MAP KINASE KINASE 4; MAP KINASE KINASE 7; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; PHOSPHORYLATION; VACCINIA; VACCINIA VIRUS;

VACCINIA VIRUS;

EID: 84855953854     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05638-11     Document Type: Article

References (46)

1. Andrade AA, et al. 2004. The vaccinia virus-stimulated mitogenactivated protein kinase (MAPK) pathway is required for virus multiplication. Biochem. J. 381:437- 446.
2. Bogoyevitch MA, Kobe B. 2006. Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases. Microbiol. Mol. Biol. Rev. 70:1061-1095.
3. Bonjardim CA, Ferreira PC, Kroon EG. 2009. Interferons: signaling, antiviral and viral evasion. Immunol. Lett. 122:1-11.
4. Campos MAS, Kroon EG. 1993. Critical period for irreversible block of vaccinia virus replication. Rev. Microbiol. 24:104 -110.
5. Chang L, Jones Y, Ellisman MH, Goldstein LS, Karin M. 2003. JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins. Dev. Cell 4:521-533.
6. Chang L, Karin M. 2001. Mammalian MAP kinase signalling cascades. Nature 410:37- 40.
7. Condit RC, Moussatche N, Traktman P. 2006. In a nutshell: structure and assembly of the vaccinia virion. Adv. Virus Res. 66:31-124.
8. Davis RJ. 2000. Signal transduction by the JNK group of MAP kinases. Cell 103:239 -252.
9. de Magalhaes JC, et al. 2001. A mitogenic signal triggered at an early stage of vaccinia virus infection: implication of MEK/ERK and protein kinase A in virus multiplication. J. Biol. Chem. 276:38353-38360.
10. Etienne-Manneville S. 2004. Actin and microtubules in cell motility: which one is in control? Traffic 5:470-477.
11. Hollinshead M, et al. 2001. Vaccinia virus utilizes microtubules for movement to the cell surface. J. Cell Biol. 154:389-402.
12. Hu W, et al. 2008. JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase. Cancer Gene Ther. 15:616-624.
13. Huang C, Jacobson K, Schaller MD. 2004. MAP kinases and cell migration. J. Cell Sci. 117:4619-4628.
14. Huang C, Rajfur Z, Borchers C, Schaller MD, Jacobson K. 2003. JNK phosphorylates paxillin and regulates cell migration. Nature 424:219 -223.
15. Husain M, Moss B. 2003. Intracellular trafficking of a palmitoylated membrane-associated protein component of enveloped vaccinia virus. J. Virol. 77:9008 -9019.
16. Joklik WK. 1962. The purification of four strains of poxvirus. Virology 18:9 -18.
17. Kates JR, McAuslan BR. 1967. Messenger RNA synthesis by a "coated" viral genome. Proc. Natl. Acad. Sci. U. S. A. 57:314 -320.
18. Kawauchi T, Chihama K, Nabeshima Y, Hoshino M. 2003. The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration. EMBO J. 22:4190-4201.
19. McFadden G. 2005. Poxvirus tropism. Nat. Rev. Microbiol. 3:201-213.
20. Moss B. 2007. Poxviridae, p 2905-2946. In Fields BN, Knipe DM, Howley PM (ed), Virology, 5th ed, vol 2. Lippincott-Raven, Philadelphia, PA.
21. Ploubidou A, et al. 2000. Vaccinia virus infection disrupts microtubule organization and centrosome function. EMBO J. 19:3932-3944.
22. Radtke K, Dohner K, Sodeik B. 2006. Viral interactions with the cytoskeleton: a hitchhiker's guide to the cell. Cell. Microbiol. 8:387-400.
23. Ridley AJ. 2001. Rho family proteins: coordinating cell responses. Trends Cell Biol. 11:471-477.
24. Rietdorf J, et al. 2001. Kinesin-dependent movement on microtubules precedes actin-based motility of vaccinia virus. Nat. Cell Biol. 3:992-1000.
25. Rochester SC, Traktman P. 1998. Characterization of the single-stranded DNA binding protein encoded by the vaccinia virus I3 gene. J. Virol. 72:2917-2926.
26. Roux PP, Blenis J. 2004. ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol. Mol. Biol. Rev. 68:320-344.
27. Sanderson CM, Way M, Smith GL. 1998. Virus-induced cell motility. J. Virol. 72:1235-1243.
28. Schepis A, Schramm B, de Haan CA, Locker JK. 2006. Vaccinia virusinduced microtubule-dependent cellular rearrangements. Traffic 7:308-323.
29. Schramm B, et al. 2006. Vaccinia-virus-induced cellular contractility facilitates the subcellular localization of the viral replication sites. Traffic 7:1352-1367.
30. Silva PN, et al. 2006. Differential role played by the MEK/ERK/EGR-1 pathway in orthopoxviruses vaccinia and cowpox biology. Biochem. J. 398:83-95.
31. Smith GL, Vanderplasschen A, Law M. 2002. The formation and function of extracellular enveloped vaccinia virus. J. Gen. Virol. 83:2915-2931.
32. Soares JA, et al. 2009. Activation of the Pi3k/Akt pathway early during vaccinia and cowpox virus infection is required for both host survival and viral replication. J. Virol. 83:6883- 6899.
33. Togel M, Wiche G, Propst F. 1998. Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain. J. Cell Biol. 143:695-707.
34. Tournier C, et al. 2000. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 288:870-874.
35. Ulloa L, Avila J, Diaz-Nido J. 1993. Heterogeneity in the phosphorylation of microtubule-associated protein MAP1B during rat brain development. J. Neurochem. 61:961-972.
36. Valderrama F, Cordeiro JV, Schleich S, Frischknecht F, Way M. 2006. Vaccinia virus-induced cell motility requires F11L-mediated inhibition of RhoA signaling. Science 311:377-381.
37. Vivanco I, et al. 2007. Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN. Cancer Cell 11:555-569.
38. Wang F, et al. 2004. Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier. Nat. Immunol. 5:1266-1274.
39. Wang G, et al. 2006. Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor. Proc. Natl. Acad. Sci. U. S. A. 103:4640-4645.
40. Ward BM, Moss B. 2001. Vaccinia virus intracellular movement is associated with microtubules and independent of actin tails. J. Virol. 75: 11651-11663.
41. Watanabe N, Kato T, Fujita A, Ishizaki T, Narumiya S. 1999. Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat. Cell Biol. 1:136 -143.
42. Waterman-Storer CM, Worthylake RA, Liu BP, Burridge K, Salmon ED. 1999. Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts. Nat. Cell Biol. 1:45-50.
43. Wittmann T, Waterman-Storer CM. 2001. Cell motility: can Rho GTPases and microtubules point the way? J. Cell Sci. 114:3795-3803.
44. Wolffe EJ, Vijaya S, Moss B. 1995. A myristylated membrane protein encoded by the vaccinia virus L1R open reading frame is the target of potent neutralizing monoclonal antibodies. Virology 211:53- 63.
45. Woodson B. 1968. Recent progress in poxvirus research. Bacteriol. Rev. 32:127-137.
46. Yang SH, Sharrocks AD, Whitmarsh AJ. 2003. Transcriptional regulation by the MAP kinase signaling cascades. Gene 320:3-21.