Electrostatic contribution of surface charge residues to the stability of a thermophilic protein: Benchmarking experimental and predicted pKa values

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Chan, Chi Ho ^a   Wilbanks, Cecily C ^b   Makhatadze, George I ^b   Wong, Kam Bo ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GLUTAMIC ACID; RIBOSOME PROTEIN; RIBOSOME PROTEIN L30E; UNCLASSIFIED DRUG; ARCHAEAL PROTEIN; RIBOSOMAL PROTEIN L30;

ARTICLE; CONTROLLED STUDY; CORRELATION COEFFICIENT; CRYSTAL STRUCTURE; MATHEMATICAL COMPUTING; MATHEMATICAL PARAMETERS; NONHUMAN; PKA; PREDICTIVE VALUE; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; QUALITY CONTROL; STATIC ELECTRICITY; SURFACE CHARGE; TEMPERATURE SENSITIVITY; THERMOCOCCUS CELER; WILD TYPE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HEAT; METABOLISM; METHODOLOGY; MUTATION; PH; PROTEIN FOLDING; PROTEIN UNFOLDING; SURFACE PROPERTY; THERMOCOCCUS; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

THERMOCOCCUS CELER;

ARCHAEAL PROTEINS; ASPARTIC ACID; BENCHMARKING; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; GLUTAMIC ACID; HOT TEMPERATURE; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MUTATION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN UNFOLDING; RIBOSOMAL PROTEINS; STATIC ELECTRICITY; SURFACE PROPERTIES; THERMOCOCCUS; THERMODYNAMICS;

EID: 84855929682     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030296     Document Type: Article

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