IL7RA polymorphisms and susceptibility to multiple sclerosis [18]

New England Journal of Medicine

Volumn 358, Issue 7, 2008, Pages 753-754

  O'Doherty, Catherine ^a   Kantarci, Orhun ^b   Vandenbroeck, Koen ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 7 RECEPTOR ALPHA;

ALLELE; CASE CONTROL STUDY; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; LETTER; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 39049159767     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc0707553     Document Type: Letter

References (5)

1. The International Multiple Sclerosis Genetics Consortium. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 2007;357:851-62.
2. Lundmark F, Duvefelt K, Iacobaeus E, et al. Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet 2007;39:1108-13.
3. Teutsch SM, Booth DR, Bennetts BH, Heard RNS, Stewart GJ. Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis. Eur J Hum Genet 2003;11:509-15.
4. Zhang Z, Duvefelt K, Svensson F, et al. Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis. Genes Immun 2005;6:145-52.
5. Kantarci OH, Goris A, Hebrink DD, et al. IFNG polymorphisms are associated with gender differences in susceptibility to multiple sclerosis. Genes Immun 2005;6:153-61.