S-farnesyl-thiopropionic acid triazoles as potent inhibitors of isoprenylcysteine carboxyl methyltransferase

ACS Medicinal Chemistry Letters

Volumn 3, Issue 1, 2012, Pages 15-19

  Bergman, Joel A ^a   Hahne, Kalub ^b   Song, Jiao ^a   Hrycyna, Christine A ^b   Gibbs, Richard A ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

dipolar cycloaddition; Isoprenylcysteine carboxyl methyltransferase (Icmt); prenylcysteine; Ras; S farnesyl thiopropionic acid (FTPA); triazole

Indexed keywords

FARNESYL THIOPROPIONIC ACID TRIAZOLE; METHYLTRANSFERASE INHIBITOR; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOMIMETICS; PRIORITY JOURNAL;

EID: 84855907701     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml200106d     Document Type: Article

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