Synthesis of desthio prenylcysteine analogs: Sulfur is important for biological activity

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 22, 2005, Pages 5080-5083

  Henriksen, Brian S ^a   Anderson, Jessica L ^b   Hrycyna, Christine A ^b   Gibbs, Richard A ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Amino acid analogs; Enzyme inhibitors; Isoprenoids; Methyltransferase

Indexed keywords

CYSTEINE DERIVATIVE; N ACETYL S FARNESYLCYSTEINE; SULFUR DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50;

CYSTEINE; INHIBITORY CONCENTRATION 50; METHYLTRANSFERASES; MOLECULAR STRUCTURE; SULFIDES; TERPENES;

EID: 25844452832     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.075     Document Type: Article

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