메뉴 건너뛰기




Volumn 30, Issue 12, 2011, Pages 1214-1222

Regulation of deoxycytidine kinase expression and sensitivity to gemcitabine by micro-RNA 330 and promoter methylation in cancer cells

Author keywords

Deoxycytidine kinase; Deoxynucleoside analogs; Gemcitabine; miR 330

Indexed keywords

DEOXYCYTIDINE KINASE; GEMCITABINE; MESSENGER RNA; MICRORNA; MICRORNA 330; UNCLASSIFIED DRUG;

EID: 84855886889     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770.2011.629271     Document Type: Article
Times cited : (31)

References (28)
  • 1
  • 2
    • 0028067217 scopus 로고
    • Development and molecular characterization of a 2',2'- difluorodeoxycytidine-resistantvariant of the human ovarian carcinoma cell line A2780
    • Ruiz van Haperen, V. W.; Veerman, G.; Eriksson, S.; Boven, E.; Stegmann, A. P.; Hermsen, M.; Vermorken, J. B.; Pinedo, H. M.; Peters, G. J. Development and molecular characterization of a 2',2'-difluorodeoxycytidine-resistantvariant of the human ovarian carcinoma cell line A2780. Cancer Res. 1994, 54, 4138-4143.
    • (1994) Cancer Res. , vol.54 , pp. 4138-4143
    • Ruiz Van Haperen, W.1    Veerman, G.2    Eriksson, S.3    Boven, E.4    Stegmann, A.P.5    Hermsen, M.6    Vermorken, J.B.7    Pinedo, H.M.8    Peters, G.J.9
  • 7
    • 0032994472 scopus 로고    scopus 로고
    • Human thymidine kinase 2: Molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates
    • DOI 10.1016/S0014-5793(98)01711-6, PII S0014579398017116
    • Wang, L.; Munch-Petersen, B.; Herrström Sjöberg, A.; Hellman, U.; Bergman, T.; Jörnvall, H.; Eriksson, S. Human thymidine kinase 2: Molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates. FEBS Lett. 1999, 443, 170-174. (Pubitemid 29078626)
    • (1999) FEBS Letters , vol.443 , Issue.2 , pp. 170-174
    • Wang, L.1    Munch-Petersen, B.2    Herrstrom Sjoberg, A.3    Hellman, U.4    Bergman, T.5    Jornvall, H.6    Eriksson, S.7
  • 8
    • 77952315463 scopus 로고    scopus 로고
    • Ribonucleotide reductases: Substrate specificity by allostery
    • Reichard, P. Ribonucleotide reductases: substrate specificity by allostery. Biochem. Biophys. Res. Commun. 2010, 396, 19-23.
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 19-23
    • Reichard, P.1
  • 9
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2', 2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine
    • Heinemann, V.; Hertel, L. W.; Grindey, G. B.; Plunkett, W. Comparison of the cellular pharmacokinetics and toxicity of 2', 2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1988, 48, 4024-4031.
    • (1988) Cancer Res. , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 10
    • 0345363057 scopus 로고    scopus 로고
    • Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity
    • DOI 10.1016/S0959-8049(99)00223-3, PII S0959804999002233
    • Spasokoukotskaja, T.; Sasvári-Székely, M.; Keszler, G.; Albertioni, F.; Eriksson, S.; Staub, M. Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity. Eur. J. Cancer 1999, 35, 1862-1867. (Pubitemid 29512320)
    • (1999) European Journal of Cancer , vol.35 , Issue.13 , pp. 1862-1867
    • Spasokoukotskaja, T.1    Sasvari-Szekely, M.2    Keszler, G.3    Albertioni, F.4    Eriksson, S.5    Staub, M.6
  • 11
    • 0038730444 scopus 로고    scopus 로고
    • Activation of deoxycytidine kinase by gamma-irradiation and inactivation by hyperosmotic shock in human lymphocytes
    • DOI 10.1016/S0006-2952(03)00182-5
    • Csapo, Z.; Keszler, G.; Safrany, G.; Spasokoukotskaja, T.; Talianidis, I.; Staub, M.; Sasvari-Szekely, M. Activation of deoxycytidine kinase by gamma-irradiation and inactivation by hyperosmotic shock in human lymphocytes. Biochem. Pharmacol. 2003, 65, 2031-2039. (Pubitemid 36629587)
    • (2003) Biochemical Pharmacology , vol.65 , Issue.12 , pp. 2031-2039
    • Csapo, Z.1    Keszler, G.2    Safrany, G.3    Spasokoukotskaja, T.4    Talianidis, I.5    Staub, M.6    Sasvari-Szekely, M.7
  • 13
    • 33646178365 scopus 로고    scopus 로고
    • Identification of in vivo phosphorylation sites on human deoxycytidine kinase: Role of Ser-74 in the control of enzyme activity
    • DOI 10.1074/jbc.M512129200
    • Smal, C.; Vertommen, D.; Bertrand, L.; Ntamashimikiro, S.; Rider, M. H.; Van Den Neste, E.; Bontemps, F. Identification of in vivo phosphorylation sites on human deoxycytidine kinase: Role of Ser-74 in the control of enzyme activity. J. Biol. Chem. 2006, 281, 4887-4893. (Pubitemid 43847750)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.8 , pp. 4887-4893
    • Smal, C.1    Vertommen, D.2    Bertrand, L.3    Ntamashimikiro, S.4    Rider, M.H.5    Van Den Neste, E.6    Bontemps, F.7
  • 14
    • 0023203849 scopus 로고
    • -1
    • Antonsson, B. E.; Avramis, V. I.; Nyce, J.; Holcenberg, J. S. Effect of 5-azacytidine and congeners on DNA methylation and expression of deoxycytidine kinase in the human lymphoid cell lines CCRF/CEM/0 and CCRF/CEM/dCk-1. Cancer Res. 1987, 47, 3672-3678. (Pubitemid 17105706)
    • (1987) Cancer Research , vol.47 , Issue.14 , pp. 3672-3678
    • Antonsson, B.E.1    Avramis, V.I.2    Nyce, J.3    Holcenberg, J.S.4
  • 15
    • 0032516637 scopus 로고    scopus 로고
    • Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA)- and 2-chloro-2'-arabino-fluoro- 2'-deoxyadenosine (CAFdA)-resistant cells
    • DOI 10.1016/S0304-3835(98)00131-1, PII S0304383598001311
    • Leegwater, P. A.; De Abreu, R. A.; Albertioni, F. Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA) - and 2-chloro-2'-arabinofluoro-2'- deoxyadenosine (CAFdA)-resistant cells. Cancer Lett. 1998, 130, 169-173. (Pubitemid 28425351)
    • (1998) Cancer Letters , vol.130 , Issue.1-2 , pp. 169-173
    • Leegwater, P.A.J.1    De Abreu, R.A.2    Albertioni, F.3
  • 16
    • 0025978611 scopus 로고
    • Induction of deoxycytidine kinase by 5-azacytidine in an HL-60 cell line resistant to arabinosylcytosine
    • Kong, X. B.; Tong, W. P.; Chou, T. C. Induction of deoxycytidine kinase by 5-azacytidine in an HL-60 cell line resistant to arabinosylcytosine. Mol. Pharmacol. 1991, 39, 250-257.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 250-257
    • Kong, X.B.1    Tong, W.P.2    Chou, T.C.3
  • 18
    • 0028903535 scopus 로고
    • Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines
    • Chen, E. H.; Johnson, E. E.; Vetter, S. M.; Mitchell, B. S. Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines. J. Clin. Invest. 1995, 95, 1660-1668.
    • (1995) J. Clin. Invest. , vol.95 , pp. 1660-1668
    • Chen, E.H.1    Johnson, E.E.2    Vetter, S.M.3    Mitchell, B.S.4
  • 19
    • 33344477448 scopus 로고    scopus 로고
    • Genomics of microRNA
    • DOI 10.1016/j.tig.2006.01.003, PII S0168952506000217
    • Kim, V. N.; Nam, J. W. Genomics of microRNA. Trends Genet. 2006, 22, 165-173. (Pubitemid 43290020)
    • (2006) Trends in Genetics , vol.22 , Issue.3 , pp. 165-173
    • Kim, V.N.1    Nam, J.-W.2
  • 20
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004, 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 21
    • 84856225885 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the role of microRNAs (microRNAs) in anticancer drug resistance and implications for clinical practice
    • in press
    • Giovannetti, E.; Erozenci, A.; Smit, J.; Danesi, R.; Peters, G. J. Molecular mechanisms underlying the role of microRNAs (microRNAs) in anticancer drug resistance and implications for clinical practice. Crit. Rev. Oncol. Hematol. 2011, in press.
    • (2011) Crit. Rev. Oncol. Hematol.
    • Giovannetti, E.1    Erozenci, A.2    Smit, J.3    Danesi, R.4    Peters, G.J.5
  • 22
    • 0025878872 scopus 로고
    • Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosen sensitivity testing
    • Keepers, Y. P.; Pizao, P. E.; Peters, G. J.; Van Ark-Otte, J.; Winograd, B.; Pinedo, H. M. Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosen sensitivity testing. Eur. J. Cancer 1991, 27, 897-900.
    • (1991) Eur. J. Cancer , vol.27 , pp. 897-900
    • Keepers, Y.P.1    Pizao, P.E.2    Peters, G.J.3    Van Ark-Otte, J.4    Winograd, B.5    Pinedo, H.M.6
  • 23
    • 33645731188 scopus 로고    scopus 로고
    • Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine
    • Giovannetti, E.; Del Tacca, M.; Mey, V.; Funel, N.; Nannizzi, S.; Ricci, S.; Orlandini, C.; Boggi, U.; Campani, D.; Del Chiaro, M. Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. Cancer Res. 2006, 66, 3928-3935.
    • (2006) Cancer Res. , vol.66 , pp. 3928-3935
    • Giovannetti, E.1    Del Tacca, M.2    Mey, V.3    Funel, N.4    Nannizzi, S.5    Ricci, S.6    Orlandini, C.7    Boggi, U.8    Campani, D.9    Del Chiaro, D.10
  • 25
    • 0037333569 scopus 로고    scopus 로고
    • Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cell lines, liver metastases and normal liver
    • DOI 10.1016/S0959-8049(02)00813-4
    • Van der Wilt, C. L.; Kroep, J. R.; Loves, W. J. P.; Rots, M. G.; Van Groeningen, C. J.; Kaspers, G. J. L.; Peters, G. J. Expression of deoxycytidine kinase in leukaemic cells compared with solid tumour cells, liver metastases and normal liver. Eur. J. Cancer 2003, 39, 691-697. (Pubitemid 36287383)
    • (2003) European Journal of Cancer , vol.39 , Issue.5 , pp. 691-697
    • Van Der Wilt, C.L.1    Kroep, J.R.2    Loves, W.J.P.3    Rots, M.G.4    Van Groeningen, C.J.5    Kaspers, G.J.6    Peters, G.J.7
  • 26
    • 79955598536 scopus 로고    scopus 로고
    • Expression of CD44 3'-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis
    • Jeyapalan, Z.; Deng, Z.; Shatseva, T.; Fang, L.; He, C.; Yang, B. B. Expression of CD44 3'-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis. Nucleic Acids Res. 2011, 39, 3026-3041.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 3026-3041
    • Jeyapalan, Z.1    Deng, Z.2    Shatseva, T.3    Fang, L.4    He, C.5    Yang, B.B.6
  • 27
    • 70349459742 scopus 로고    scopus 로고
    • MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation
    • Lee, K. H.; Chen, Y. L.; Yeh, S. D.; Hsiao, M.; Lin, J. T.; Goan, Y. G.; Lu, P. J. MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation. Oncogene. 2009, 28, 3360-3370.
    • (2009) Oncogene. , vol.28 , pp. 3360-3370
    • Lee, K.H.1    Chen, Y.L.2    Yeh, S.D.3    Hsiao, M.4    Lin, J.T.5    Goan, Y.G.6    Lu, P.J.7
  • 28
    • 29244476907 scopus 로고    scopus 로고
    • Pyrimidine and purine analogues, effects on cell cycle regulation and the role of cell cycle inhibitors to enhance their cytotoxicity
    • DOI 10.1080/15257770500269556
    • Sigmond, J.; Peters, G. J. Pyrimidine and purine analogues: Effects on cell cycle regulation and the role of cell cycle inhibitors to enhance their cytotoxicity. Nucleos. Nucleot. Nucl. Acids 2005, 24, 1997-2022. (Pubitemid 41831843)
    • (2005) Nucleosides, Nucleotides and Nucleic Acids , vol.24 , Issue.10-12 , pp. 1997-2022
    • Sigmond, J.1    Peters, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.