메뉴 건너뛰기




Volumn 75, Issue 4, 2012, Pages 1089-1098

Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor

(17)  Kikuta, Kazutaka a,b,i   Kubota, Daisuke a,c   Saito, Tsuyoshi c   Orita, Hajime d   Yoshida, Akihiko e,f   Tsuda, Hitoshi e   Suehara, Yoshiyuki c   Katai, Hitoshi e   Shimada, Yasuhiro e   Toyama, Yoshiaki b   Sato, Koichi d   Yao, Takashi c   Kaneko, Kazuo c   Beppu, Yasuo e   Murakami, Yasufumi g,h   Kawai, Akira e   Kondo, Tadashi a  


Author keywords

2D DIGE; ATP dependent RNA helicase DDX39; Biomarker; Gastrointestinal stromal tumor; Prognosis

Indexed keywords

ADENOSINE TRIPHOSPHATE; PROTEIN TYROSINE KINASE INHIBITOR; RNA HELICASE;

EID: 84855886307     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2011.10.005     Document Type: Article
Times cited : (44)

References (44)
  • 2
    • 0036301863 scopus 로고    scopus 로고
    • Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review
    • Miettinen M., El-Rifai W., HLS L., Lasota J. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol 2002, 33:478-483.
    • (2002) Hum Pathol , vol.33 , pp. 478-483
    • Miettinen, M.1    El-Rifai, W.2    Hls, L.3    Lasota, J.4
  • 3
    • 39349113732 scopus 로고    scopus 로고
    • Adjuvant imatinib mesylate increases recurrence free survival (RFS) in patients with completely resected localized primary gastrointestinal stromal tumor (GIST). 2007. North American Intergroup Phase III trial ACOSOG Z9001
    • Dematteo R.P., Owzar K., Maki R. Adjuvant imatinib mesylate increases recurrence free survival (RFS) in patients with completely resected localized primary gastrointestinal stromal tumor (GIST). 2007. North American Intergroup Phase III trial ACOSOG Z9001. J Clin Oncol, ASCO Annual Meeting Proceedings 2007, 25:10079.
    • (2007) J Clin Oncol, ASCO Annual Meeting Proceedings , vol.25 , pp. 10079
    • Dematteo, R.P.1    Owzar, K.2    Maki, R.3
  • 5
    • 12144291080 scopus 로고    scopus 로고
    • Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group
    • Debiec-Rychter M., Dumez H., Judson I., Wasag B., Verweij J., Brown M., et al. Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer 2004, 40:689-695.
    • (2004) Eur J Cancer , vol.40 , pp. 689-695
    • Debiec-Rychter, M.1    Dumez, H.2    Judson, I.3    Wasag, B.4    Verweij, J.5    Brown, M.6
  • 6
    • 33746401591 scopus 로고    scopus 로고
    • KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours
    • Debiec-Rychter M., Sciot R., Le Cesne A., Schlemmer M., Hohenberger P., van Oosterom A.T., et al. KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer 2006, 42:1093-1103.
    • (2006) Eur J Cancer , vol.42 , pp. 1093-1103
    • Debiec-Rychter, M.1    Sciot, R.2    Le Cesne, A.3    Schlemmer, M.4    Hohenberger, P.5    van Oosterom, A.T.6
  • 8
    • 19944427609 scopus 로고    scopus 로고
    • Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study
    • Schneider-Stock R., Boltze C., Lasota J., Peters B., Corless C.L., Ruemmele P., et al. Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study. AACR 2005, 638-645.
    • (2005) AACR , pp. 638-645
    • Schneider-Stock, R.1    Boltze, C.2    Lasota, J.3    Peters, B.4    Corless, C.L.5    Ruemmele, P.6
  • 9
    • 41549148806 scopus 로고    scopus 로고
    • Pfetin as a prognostic biomarker of gastrointestinal stromal tumors revealed by proteomics
    • Suehara Y., Kondo T., Seki K., Shibata T., Fujii K., Gotoh M., et al. Pfetin as a prognostic biomarker of gastrointestinal stromal tumors revealed by proteomics. Clin Cancer Res 2008, 14:1707-1717.
    • (2008) Clin Cancer Res , vol.14 , pp. 1707-1717
    • Suehara, Y.1    Kondo, T.2    Seki, K.3    Shibata, T.4    Fujii, K.5    Gotoh, M.6
  • 11
    • 0036329780 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumor: consistent CD117 immunostaining for diagnosis, and prognostic classification based on tumor size and MIB-1 grade
    • Hasegawa T., Matsuno Y., Shimoda T., Hirohashi S. Gastrointestinal stromal tumor: consistent CD117 immunostaining for diagnosis, and prognostic classification based on tumor size and MIB-1 grade. Hum Pathol 2002, 33:669-676.
    • (2002) Hum Pathol , vol.33 , pp. 669-676
    • Hasegawa, T.1    Matsuno, Y.2    Shimoda, T.3    Hirohashi, S.4
  • 12
    • 0343376097 scopus 로고    scopus 로고
    • Difference gel electrophoresis: a single gel method for detecting changes in protein extracts
    • Unlu M., Morgan M.E., Minden J.S. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis 1997, 18:2071-2077.
    • (1997) Electrophoresis , vol.18 , pp. 2071-2077
    • Unlu, M.1    Morgan, M.E.2    Minden, J.S.3
  • 13
    • 4544278712 scopus 로고    scopus 로고
    • Proteomic signature corresponding to alpha fetoprotein expression in liver cancer cells
    • Yokoo H., Kondo T., Fujii K., Yamada T., Todo S., Hirohashi S. Proteomic signature corresponding to alpha fetoprotein expression in liver cancer cells. Hepatology 2004, 40:609-617.
    • (2004) Hepatology , vol.40 , pp. 609-617
    • Yokoo, H.1    Kondo, T.2    Fujii, K.3    Yamada, T.4    Todo, S.5    Hirohashi, S.6
  • 14
    • 33747762687 scopus 로고    scopus 로고
    • Proteomic signatures corresponding to histological classification and grading of soft-tissue sarcomas
    • Suehara Y., Kondo T., Fujii K., Hasegawa T., Kawai A., Seki K., et al. Proteomic signatures corresponding to histological classification and grading of soft-tissue sarcomas. Proteomics 2006, 6:4402-4409.
    • (2006) Proteomics , vol.6 , pp. 4402-4409
    • Suehara, Y.1    Kondo, T.2    Fujii, K.3    Hasegawa, T.4    Kawai, A.5    Seki, K.6
  • 15
    • 34147161968 scopus 로고    scopus 로고
    • Application of highly sensitive fluorescent dyes (CyDye DIGE Fluor saturation dyes) to laser microdissection and two-dimensional difference gel electrophoresis (2D-DIGE) for cancer proteomics
    • Kondo T., Hirohashi S. Application of highly sensitive fluorescent dyes (CyDye DIGE Fluor saturation dyes) to laser microdissection and two-dimensional difference gel electrophoresis (2D-DIGE) for cancer proteomics. Nat Protoc 2007, 1:2940-2956.
    • (2007) Nat Protoc , vol.1 , pp. 2940-2956
    • Kondo, T.1    Hirohashi, S.2
  • 16
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan E. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958, 53:457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.1
  • 17
    • 0000336139 scopus 로고
    • Regression models and life table
    • Cox D. Regression models and life table. J R Stat Soc 1972, 34:187-220.
    • (1972) J R Stat Soc , vol.34 , pp. 187-220
    • Cox, D.1
  • 18
    • 0019311086 scopus 로고
    • Very-high-resolution two-dimensional gel electrophoresis of proteins using giant gels
    • Voris B.P., Young D.A. Very-high-resolution two-dimensional gel electrophoresis of proteins using giant gels. Anal Biochem 1980, 104:478-484.
    • (1980) Anal Biochem , vol.104 , pp. 478-484
    • Voris, B.P.1    Young, D.A.2
  • 20
    • 0037253267 scopus 로고    scopus 로고
    • A novel experimental design for comparative two-dimensional gel analysis: two-dimensional difference gel electrophoresis incorporating a pooled internal standard
    • Alban A., David S.O., Bjorkesten L., Andersson C., Sloge E., Lewis S., et al. A novel experimental design for comparative two-dimensional gel analysis: two-dimensional difference gel electrophoresis incorporating a pooled internal standard. Proteomics 2003, 3:36-44.
    • (2003) Proteomics , vol.3 , pp. 36-44
    • Alban, A.1    David, S.O.2    Bjorkesten, L.3    Andersson, C.4    Sloge, E.5    Lewis, S.6
  • 21
    • 1342328149 scopus 로고    scopus 로고
    • Superoxide dismutases in malignant cells and human tumors
    • Kinnula V.L., Crapo J.D. Superoxide dismutases in malignant cells and human tumors. Free Radic Biol Med 2004, 36:718-744.
    • (2004) Free Radic Biol Med , vol.36 , pp. 718-744
    • Kinnula, V.L.1    Crapo, J.D.2
  • 22
    • 33846660976 scopus 로고    scopus 로고
    • Intracellular characterization of DDX39, a novel growth-associated RNA helicase
    • Sugiura T., Sakurai K., Nagano Y. Intracellular characterization of DDX39, a novel growth-associated RNA helicase. Exp Cell Res 2007, 313:782-790.
    • (2007) Exp Cell Res , vol.313 , pp. 782-790
    • Sugiura, T.1    Sakurai, K.2    Nagano, Y.3
  • 23
    • 40949137131 scopus 로고    scopus 로고
    • DDX39, upregulated in lung squamous cell cancer, displays RNA helicase activities and promotes cancer cell growth
    • Sugiura T., Nagano Y., Noguchi Y. DDX39, upregulated in lung squamous cell cancer, displays RNA helicase activities and promotes cancer cell growth. Cancer Biol Ther 2007, 6:957-964.
    • (2007) Cancer Biol Ther , vol.6 , pp. 957-964
    • Sugiura, T.1    Nagano, Y.2    Noguchi, Y.3
  • 24
    • 79960329911 scopus 로고    scopus 로고
    • Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection
    • Yoo H.H., Chung I.K. Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection. Aging Cell 2011, 10:557-571.
    • (2011) Aging Cell , vol.10 , pp. 557-571
    • Yoo, H.H.1    Chung, I.K.2
  • 25
    • 62849096370 scopus 로고    scopus 로고
    • Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial
    • Dematteo R.P., Ballman K.V., Antonescu C.R., Maki R.G., Pisters P.W., Demetri G.D., et al. Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. Lancet 2009, 373:1097-1104.
    • (2009) Lancet , vol.373 , pp. 1097-1104
    • Dematteo, R.P.1    Ballman, K.V.2    Antonescu, C.R.3    Maki, R.G.4    Pisters, P.W.5    Demetri, G.D.6
  • 26
    • 33845717325 scopus 로고    scopus 로고
    • Immunohistochemical expression of p16INK4A, Ki-67, and Mcm2 proteins in gastrointestinal stromal tumors: prognostic implications and correlations with risk stratification of NIH consensus criteria
    • Huang H.Y., Huang W.W., Lin C.N., Eng H.L., Li S.H., Li C.F., et al. Immunohistochemical expression of p16INK4A, Ki-67, and Mcm2 proteins in gastrointestinal stromal tumors: prognostic implications and correlations with risk stratification of NIH consensus criteria. Ann Surg Oncol 2006, 13:1633-1644.
    • (2006) Ann Surg Oncol , vol.13 , pp. 1633-1644
    • Huang, H.Y.1    Huang, W.W.2    Lin, C.N.3    Eng, H.L.4    Li, S.H.5    Li, C.F.6
  • 27
    • 54249150409 scopus 로고    scopus 로고
    • P16 expression differentiates high-risk gastrointestinal stromal tumor and predicts poor outcome
    • Schmieder M., Wolf S., Danner B., Stoehr S., Juchems M.S., Wuerl P., et al. p16 expression differentiates high-risk gastrointestinal stromal tumor and predicts poor outcome. Neoplasia 2008, 10:1154-1162.
    • (2008) Neoplasia , vol.10 , pp. 1154-1162
    • Schmieder, M.1    Wolf, S.2    Danner, B.3    Stoehr, S.4    Juchems, M.S.5    Wuerl, P.6
  • 28
    • 19944427609 scopus 로고    scopus 로고
    • Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study
    • Schneider-Stock R., Boltze C., Lasota J., Peters B., Corless C.L., Ruemmele P., et al. Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study. Clin Cancer Res 2005, 11:638-645.
    • (2005) Clin Cancer Res , vol.11 , pp. 638-645
    • Schneider-Stock, R.1    Boltze, C.2    Lasota, J.3    Peters, B.4    Corless, C.L.5    Ruemmele, P.6
  • 30
    • 33846603697 scopus 로고    scopus 로고
    • Expression of COX-2, PCNA, Ki-67 and p53 in gastrointestinal stromal tumors and its relationship with histopathological parameters
    • Gumurdulu D., Erdogan S., Kayaselcuk F., Seydaoglu G., Parsak C.K., Demircan O., et al. Expression of COX-2, PCNA, Ki-67 and p53 in gastrointestinal stromal tumors and its relationship with histopathological parameters. World J Gastroenterol 2007, 13:426-431.
    • (2007) World J Gastroenterol , vol.13 , pp. 426-431
    • Gumurdulu, D.1    Erdogan, S.2    Kayaselcuk, F.3    Seydaoglu, G.4    Parsak, C.K.5    Demircan, O.6
  • 32
    • 70350341013 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression and connection with tumor recurrence and histopathologic parameters in gastrointestinal stromal tumors
    • Turkoz H.K., Alkan I., Sisman S., Ozcan D. Cyclooxygenase-2 expression and connection with tumor recurrence and histopathologic parameters in gastrointestinal stromal tumors. APMIS 2009, 117:825-830.
    • (2009) APMIS , vol.117 , pp. 825-830
    • Turkoz, H.K.1    Alkan, I.2    Sisman, S.3    Ozcan, D.4
  • 33
    • 46149111291 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients
    • Braconi C., Bracci R., Bearzi I., Bianchi F., Sabato S., Mandolesi A., et al. Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients. Ann Oncol 2008, 19:1293-1298.
    • (2008) Ann Oncol , vol.19 , pp. 1293-1298
    • Braconi, C.1    Bracci, R.2    Bearzi, I.3    Bianchi, F.4    Sabato, S.5    Mandolesi, A.6
  • 34
    • 34748818101 scopus 로고    scopus 로고
    • Prediction of aggressiveness of gastrointestinal stromal tumours based on immunostaining with bcl-2, Ki-67 and p53
    • Meara R.S., Cangiarella J., Simsir A., Horton D., Eltoum I., Chhieng D.C. Prediction of aggressiveness of gastrointestinal stromal tumours based on immunostaining with bcl-2, Ki-67 and p53. Cytopathology 2007, 18:283-289.
    • (2007) Cytopathology , vol.18 , pp. 283-289
    • Meara, R.S.1    Cangiarella, J.2    Simsir, A.3    Horton, D.4    Eltoum, I.5    Chhieng, D.C.6
  • 35
    • 33645826059 scopus 로고    scopus 로고
    • Expression of Bcl-2 in gastrointestinal stromal tumors: correlation with progression-free survival in 81 patients treated with imatinib mesylate
    • Steinert D.M., Oyarzo M., Wang X., Choi H., Thall P.F., Medeiros L.J., et al. Expression of Bcl-2 in gastrointestinal stromal tumors: correlation with progression-free survival in 81 patients treated with imatinib mesylate. Cancer 2006, 106:1617-1623.
    • (2006) Cancer , vol.106 , pp. 1617-1623
    • Steinert, D.M.1    Oyarzo, M.2    Wang, X.3    Choi, H.4    Thall, P.F.5    Medeiros, L.J.6
  • 36
    • 44449129635 scopus 로고    scopus 로고
    • Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours
    • Di Vizio D., Demichelis F., Simonetti S., Pettinato G., Terracciano L., Tornillo L., et al. Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours. BMC Cancer 2008, 8:134.
    • (2008) BMC Cancer , vol.8 , pp. 134
    • Di Vizio, D.1    Demichelis, F.2    Simonetti, S.3    Pettinato, G.4    Terracciano, L.5    Tornillo, L.6
  • 37
    • 33748596056 scopus 로고    scopus 로고
    • Clinicopathological and immunohistochemical analysis of gastrointestinal stromal tumor
    • Liu F.Y., Qi J.P., Xu F.L., Wu A.P. Clinicopathological and immunohistochemical analysis of gastrointestinal stromal tumor. World J Gastroenterol 2006, 12:4161-4165.
    • (2006) World J Gastroenterol , vol.12 , pp. 4161-4165
    • Liu, F.Y.1    Qi, J.P.2    Xu, F.L.3    Wu, A.P.4
  • 39
    • 34250623276 scopus 로고    scopus 로고
    • Significance of CD44 expression in gastrointestinal stromal tumors in relation to disease progression and survival
    • Hsu K.H., Tsai H.W., Shan Y.S., Lin P.W. Significance of CD44 expression in gastrointestinal stromal tumors in relation to disease progression and survival. World J Surg 2007, 31:1438-1444.
    • (2007) World J Surg , vol.31 , pp. 1438-1444
    • Hsu, K.H.1    Tsai, H.W.2    Shan, Y.S.3    Lin, P.W.4
  • 43
    • 74949127091 scopus 로고    scopus 로고
    • Pfetin as a prognostic biomarker in gastrointestinal stromal tumor: novel monoclonal antibody and external validation study in multiple clinical facilities
    • Kikuta K., Gotoh M., Kanda T., Tochigi N., Shimoda T., Hasegawa T., et al. Pfetin as a prognostic biomarker in gastrointestinal stromal tumor: novel monoclonal antibody and external validation study in multiple clinical facilities. Jpn J Clin Oncol 2010, 40:60-72.
    • (2010) Jpn J Clin Oncol , vol.40 , pp. 60-72
    • Kikuta, K.1    Gotoh, M.2    Kanda, T.3    Tochigi, N.4    Shimoda, T.5    Hasegawa, T.6
  • 44
    • 80053502871 scopus 로고    scopus 로고
    • Pfetin as a prognostic biomarker for gastrointestinal stromal tumor: validation study in multiple clinical facilities
    • Kubota D., Orita H., Yoshida A., Gotoh M., Kanda T., Tsuda H., et al. Pfetin as a prognostic biomarker for gastrointestinal stromal tumor: validation study in multiple clinical facilities. Jpn J Clin Oncol 2011, 41:1194-1202.
    • (2011) Jpn J Clin Oncol , vol.41 , pp. 1194-1202
    • Kubota, D.1    Orita, H.2    Yoshida, A.3    Gotoh, M.4    Kanda, T.5    Tsuda, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.