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Volumn 8, Issue , 2008, Pages

Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; JAB 1 PROTEIN; KI 67 ANTIGEN; S PHASE KINASE ASSOCIATED PROTEIN 2; COPS5 PROTEIN, HUMAN; PEPTIDE HYDROLASE; S PHASE KINASE ASSOCIATED PROTEIN; SIGNAL PEPTIDE; TUMOR MARKER;

EID: 44449129635     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-8-134     Document Type: Article
Times cited : (22)

References (35)
  • 2
    • 33749459756 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis, and differential diagnosis
    • 17090188
    • Miettinen M Lasota J Gastrointestinal stromal tumors: Review on morphology, molecular pathology, prognosis, and differential diagnosis Arch Pathol Lab Med 2006, 130(10):1466-1478 17090188
    • (2006) Arch Pathol Lab Med , vol.130 , Issue.10 , pp. 1466-1478
    • Miettinen, M.1    Lasota, J.2
  • 4
    • 13044305289 scopus 로고    scopus 로고
    • PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
    • 26859 10339565 10.1073/pnas.96.11.6199
    • Sun H Lesche R Li DM Liliental J Zhang H Gao J Gavrilova N Mueller B Liu X Wu H PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway Proc Natl Acad Sci U S A 1999, 96(11):6199-6204 26859 10339565 10.1073/pnas.96.11.6199
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.11 , pp. 6199-6204
    • Sun, H.1    Lesche, R.2    Li, D.M.3    Liliental, J.4    Zhang, H.5    Gao, J.6    Gavrilova, N.7    Mueller, B.8    Liu, X.9    Wu, H.10
  • 7
    • 33750618188 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: Pathology and prognosis at different sites
    • 10.1053/j.semdp.2006.09.001 17193820
    • Miettinen M Lasota J Gastrointestinal stromal tumors: Pathology and prognosis at different sites Semin Diagn Pathol 2006, 23(2):70-83 10.1053/j.semdp.2006.09.001 17193820
    • (2006) Semin Diagn Pathol , vol.23 , Issue.2 , pp. 70-83
    • Miettinen, M.1    Lasota, J.2
  • 8
    • 10744233692 scopus 로고    scopus 로고
    • Prognostic indicators for gastrointestinal stromal tumours: A clinicopathological and immunohistochemical study of 108 resected cases of the stomach
    • 10.1046/j.1365-2559.2003.01665.x 12877726
    • Wong NA Young R Malcomson RD Nayar AG Jamieson LA Save VE Carey FA Brewster DH Han C Al-Nafussi A Prognostic indicators for gastrointestinal stromal tumours: A clinicopathological and immunohistochemical study of 108 resected cases of the stomach Histopathology 2003, 43(2):118-126 10.1046/j.1365-2559.2003.01665.x 12877726
    • (2003) Histopathology , vol.43 , Issue.2 , pp. 118-126
    • Wong, N.A.1    Young, R.2    Malcomson, R.D.3    Nayar, A.G.4    Jamieson, L.A.5    Save, V.E.6    Carey, F.A.7    Brewster, D.H.8    Han, C.9    Al-Nafussi, A.10
  • 9
    • 0029747162 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitors (CKIs) and hematological malignancies
    • 10.1007/s00282-996-0313-4 8891723
    • Baghdassarian N Ffrench M Cyclin-dependent kinase inhibitors (CKIs) and hematological malignancies Hematol Cell Ther 1996, 38(4):313-323 10.1007/ s00282-996-0313-4 8891723
    • (1996) Hematol Cell Ther , vol.38 , Issue.4 , pp. 313-323
    • Baghdassarian, N.1    Ffrench, M.2
  • 10
    • 33747181073 scopus 로고    scopus 로고
    • Prognostic role of p27Kip1 deregulation in colorectal cancer
    • 10.1002/cncr.22073 16826582
    • Hershko DD Shapira M Prognostic role of p27Kip1 deregulation in colorectal cancer Cancer 2006, 107(4):668-675 10.1002/cncr.22073 16826582
    • (2006) Cancer , vol.107 , Issue.4 , pp. 668-675
    • Hershko, D.D.1    Shapira, M.2
  • 11
    • 0038082030 scopus 로고    scopus 로고
    • The prognosis in spindle-cell sarcoma depends on the expression of cyclin-dependent kinase inhibitor p27(Kip1) and cyclin E
    • 10.1111/j.1349-7006.2003.tb01456.x 12824885
    • Goto Y Kawauchi S Ihara K Ikemoto K Ohi R Kawai S Sasaki K The prognosis in spindle-cell sarcoma depends on the expression of cyclin-dependent kinase inhibitor p27(Kip1) and cyclin E Cancer Sci 2003, 94(5):412-417 10.1111/j.1349-7006.2003.tb01456.x 12824885
    • (2003) Cancer Sci , vol.94 , Issue.5 , pp. 412-417
    • Goto, Y.1    Kawauchi, S.2    Ihara, K.3    Ikemoto, K.4    Ohi, R.5    Kawai, S.6    Sasaki, K.7
  • 15
    • 23444443877 scopus 로고    scopus 로고
    • Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade
    • 10.1016/j.humpath.2005.03.012 16084954
    • Nakamura N Yamamoto H Yao T Oda Y Nishiyama K Imamura M Yamada T Nawata H Tsuneyoshi M Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade Hum Pathol 2005, 36(7):828-837 10.1016/ j.humpath.2005.03.012 16084954
    • (2005) Hum Pathol , vol.36 , Issue.7 , pp. 828-837
    • Nakamura, N.1    Yamamoto, H.2    Yao, T.3    Oda, Y.4    Nishiyama, K.5    Imamura, M.6    Yamada, T.7    Nawata, H.8    Tsuneyoshi, M.9
  • 16
    • 33745469852 scopus 로고    scopus 로고
    • Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: Markers with potential prognostic implications
    • 10.1016/j.humpath.2006.01.023 16733203
    • Sabah M Cummins R Leader M Kay E Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: Markers with potential prognostic implications Hum Pathol 2006, 37(6):648-655 10.1016/ j.humpath.2006.01.023 16733203
    • (2006) Hum Pathol , vol.37 , Issue.6 , pp. 648-655
    • Sabah, M.1    Cummins, R.2    Leader, M.3    Kay, E.4
  • 17
    • 0141519092 scopus 로고    scopus 로고
    • Cyclin D3 immunoreactivity in gastrointestinal stromal tumors is independent of cyclin D3 gene amplification and is associated with nuclear p27 accumulation
    • 10.1097/01.MP.0000085026.38856.B9 13679452
    • Pruneri G Mazzarol G Fabris S Del Curto B Bertolini F Neri A Viale G Cyclin D3 immunoreactivity in gastrointestinal stromal tumors is independent of cyclin D3 gene amplification and is associated with nuclear p27 accumulation Mod Pathol 2003, 16(9):886-892 10.1097/ 01.MP.0000085026.38856.B9 13679452
    • (2003) Mod Pathol , vol.16 , Issue.9 , pp. 886-892
    • Pruneri, G.1    Mazzarol, G.2    Fabris, S.3    Del Curto, B.4    Bertolini, F.5    Neri, A.6    Viale, G.7
  • 18
    • 34248203270 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor, p27, has no correlation with the malignant potential of GIST
    • 10.1159/000101457 17406118
    • Shirin H Kravtsov V Shahmurov M Shabat VS Krinshpon I Alin A Avinoach I Avni Y The cyclin-dependent kinase inhibitor, p27, has no correlation with the malignant potential of GIST Digestion 2007, 75(1):4-9 10.1159/ 000101457 17406118
    • (2007) Digestion , vol.75 , Issue.1 , pp. 4-9
    • Shirin, H.1    Kravtsov, V.2    Shahmurov, M.3    Shabat, V.S.4    Krinshpon, I.5    Alin, A.6    Avinoach, I.7    Avni, Y.8
  • 19
    • 0037127256 scopus 로고    scopus 로고
    • The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex
    • 10.1074/jbc.M104431200 11704659
    • Tomoda K Kubota Y Arata Y Mori S Maeda M Tanaka T Yoshida M Yoneda-Kato N Kato JY The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex J Biol Chem 2002, 277(3):2302-2310 10.1074/jbc.M104431200 11704659
    • (2002) J Biol Chem , vol.277 , Issue.3 , pp. 2302-2310
    • Tomoda, K.1    Kubota, Y.2    Arata, Y.3    Mori, S.4    Maeda, M.5    Tanaka, T.6    Yoshida, M.7    Yoneda-Kato, N.8    Kato, J.Y.9
  • 20
    • 4644259385 scopus 로고    scopus 로고
    • Immunohistochemical study of Skp2 and Jab1, two key molecules in the degradation of P27, in lung adenocarcinoma
    • 10.1111/j.1440-1827.2004.01679.x 15363035
    • Goto A Niki T Moriyama S Funata N Moriyama H Nishimura Y Tsuchida R Kato JY Fukayama M Immunohistochemical study of Skp2 and Jab1, two key molecules in the degradation of P27, in lung adenocarcinoma Pathol Int 2004, 54(9):675-681 10.1111/j.1440-1827.2004.01679.x 15363035
    • (2004) Pathol Int , vol.54 , Issue.9 , pp. 675-681
    • Goto, A.1    Niki, T.2    Moriyama, S.3    Funata, N.4    Moriyama, H.5    Nishimura, Y.6    Tsuchida, R.7    Kato, J.Y.8    Fukayama, M.9
  • 21
    • 0029024015 scopus 로고
    • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
    • 10.1126/science.7624798 7624798
    • Pagano M Tam SW Theodoras AM Beer-Romero P Del Sal G Chau V Yew PR Draetta GF Rolfe M Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27 Science 1995, 269(5224):682-685 10.1126/science.7624798 7624798
    • (1995) Science , vol.269 , Issue.5224 , pp. 682-685
    • Pagano, M.1    Tam, S.W.2    Theodoras, A.M.3    Beer-Romero, P.4    Del Sal, G.5    Chau, V.6    Yew, P.R.7    Draetta, G.F.8    Rolfe, M.9
  • 23
    • 0037441785 scopus 로고    scopus 로고
    • Skp2 protein expression in soft tissue sarcomas
    • 10.1200/JCO.2003.05.112 12586812
    • Oliveira AM Okuno SH Nascimento AG Lloyd RV Skp2 protein expression in soft tissue sarcomas J Clin Oncol 2003, 21(4):722-727 10.1200/ JCO.2003.05.112 12586812
    • (2003) J Clin Oncol , vol.21 , Issue.4 , pp. 722-727
    • Oliveira, A.M.1    Okuno, S.H.2    Nascimento, A.G.3    Lloyd, R.V.4
  • 24
    • 0037567489 scopus 로고    scopus 로고
    • Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1)
    • 12782606
    • Kouvaraki MA Rassidakis GZ Tian L Kumar R Kittas C Claret FX Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1) Cancer Res 2003, 63(11):2977-2981 12782606
    • (2003) Cancer Res , vol.63 , Issue.11 , pp. 2977-2981
    • Kouvaraki, M.A.1    Rassidakis, G.Z.2    Tian, L.3    Kumar, R.4    Kittas, C.5    Claret, F.X.6
  • 25
    • 33748990915 scopus 로고    scopus 로고
    • Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma
    • 1780177 16951171 10.1158/0008-5472.CAN-06-0975
    • Kouvaraki MA Korapati AL Rassidakis GZ Tian L Zhang Q Chiao P Ho L Evans DB Claret FX Potential role of Jun activation domain-binding protein 1 as a negative regulator of p27kip1 in pancreatic adenocarcinoma Cancer Res 2006, 66(17):88581-8589 1780177 16951171 10.1158/ 0008-5472.CAN-06-0975
    • (2006) Cancer Res , vol.66 , pp. 8581-8589
    • Kouvaraki, M.A.1    Korapati, A.L.2    Rassidakis, G.Z.3    Tian, L.4    Zhang, Q.5    Chiao, P.6    Ho, L.7    Evans, D.B.8    Claret, F.X.9
  • 26
    • 14744270391 scopus 로고    scopus 로고
    • Analysis of prognostic and immunohistochemical factors in gastrointestinal stromal tumors with malignant potential
    • 10.1016/j.gassur.2004.07.003 15749606
    • Ozguc H Yilmazlar T Yerci O Soylu R Tumay V Filiz G Zorluoglu A Analysis of prognostic and immunohistochemical factors in gastrointestinal stromal tumors with malignant potential J Gastrointest Surg 2005, 9(3):418-429 10.1016/j.gassur.2004.07.003 15749606
    • (2005) J Gastrointest Surg , vol.9 , Issue.3 , pp. 418-429
    • Ozguc, H.1    Yilmazlar, T.2    Yerci, O.3    Soylu, R.4    Tumay, V.5    Filiz, G.6    Zorluoglu, A.7
  • 27
    • 33846243226 scopus 로고    scopus 로고
    • Diagnostic morphological features of PDGFRA-mutated gastrointestinal stromal tumors: Molecular genetic and histologic analysis of 60 cases of gastric gastrointestinal stromal tumors
    • 10.1016/j.anndiagpath.2006.10.002 17240304
    • Daum O Grossmann P Vanecek T Sima R Mukensnabl P Michal M Diagnostic morphological features of PDGFRA-mutated gastrointestinal stromal tumors: Molecular genetic and histologic analysis of 60 cases of gastric gastrointestinal stromal tumors Ann Diagn Pathol 2007, 11(1):27-33 10.1016/j.anndiagpath.2006.10.002 17240304
    • (2007) Ann Diagn Pathol , vol.11 , Issue.1 , pp. 27-33
    • Daum, O.1    Grossmann, P.2    Vanecek, T.3    Sima, R.4    Mukensnabl, P.5    Michal, M.6
  • 29
    • 0036861277 scopus 로고    scopus 로고
    • Over-expression of p45(SKP2) in Kaposi's sarcoma correlates with higher tumor stage and extracutaneous involvement but is not directly related to p27(KIP1) down-regulation
    • 10.1097/01.MP.0000036589.99516.D6 12429803
    • Penin RM Fernandez-Figueras MT Puig L Rex J Ferrandiz C Ariza A Over-expression of p45(SKP2) in Kaposi's sarcoma correlates with higher tumor stage and extracutaneous involvement but is not directly related to p27(KIP1) down-regulation Mod Pathol 2002, 15(11):1227-1235 10.1097/ 01.MP.0000036589.99516.D6 12429803
    • (2002) Mod Pathol , vol.15 , Issue.11 , pp. 1227-1235
    • Penin, R.M.1    Fernandez-Figueras, M.T.2    Puig, L.3    Rex, J.4    Ferrandiz, C.5    Ariza, A.6
  • 31
    • 0141706607 scopus 로고    scopus 로고
    • p27 Labeling index and proliferation in gastrointestinal stromal tumors: Correlations with clinicopathologic factors and recurrence
    • 10.1093/jjco/hyg071 12949061
    • Gelen T Elpek GO Aksoy NH Ogus M Keles N p27 Labeling index and proliferation in gastrointestinal stromal tumors: Correlations with clinicopathologic factors and recurrence Jpn J Clin Oncol 2003, 33(7):346-352 10.1093/jjco/hyg071 12949061
    • (2003) Jpn J Clin Oncol , vol.33 , Issue.7 , pp. 346-352
    • Gelen, T.1    Elpek, G.O.2    Aksoy, N.H.3    Ogus, M.4    Keles, N.5
  • 32
    • 33750618580 scopus 로고    scopus 로고
    • Correlation of enhanced cell turnover with prognosis of gastrointestinal stromal tumors of the stomach: Relevance of cellularity and p27kip1
    • 10.1111/j.1440-1827.2006.02038.x 17096729
    • Nemoto Y Mikami T Hana K Kikuchi S Kobayashi N Watanabe M Okayasu I Correlation of enhanced cell turnover with prognosis of gastrointestinal stromal tumors of the stomach: Relevance of cellularity and p27kip1 Pathol Int 2006, 56(12):724-731 10.1111/j.1440-1827.2006.02038.x 17096729
    • (2006) Pathol Int , vol.56 , Issue.12 , pp. 724-731
    • Nemoto, Y.1    Mikami, T.2    Hana, K.3    Kikuchi, S.4    Kobayashi, N.5    Watanabe, M.6    Okayasu, I.7
  • 33
    • 33846321913 scopus 로고    scopus 로고
    • Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases
    • 10.1016/j.cell.2006.11.047 17254966
    • Grimmler M Wang Y Mund T Cilensek Z Keidel EM Waddell MB Jakel H Kullmann M Kriwacki RW Hengst L Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases Cell 2007, 128(2):269-280 10.1016/j.cell.2006.11.047 17254966
    • (2007) Cell , vol.128 , Issue.2 , pp. 269-280
    • Grimmler, M.1    Wang, Y.2    Mund, T.3    Cilensek, Z.4    Keidel, E.M.5    Waddell, M.B.6    Jakel, H.7    Kullmann, M.8    Kriwacki, R.W.9    Hengst, L.10
  • 34
    • 0033176887 scopus 로고    scopus 로고
    • SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
    • 10.1038/12013 10559916
    • Carrano AC Eytan E Hershko A Pagano M SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 Nat Cell Biol 1999, 1(4):193-199 10.1038/12013 10559916
    • (1999) Nat Cell Biol , vol.1 , Issue.4 , pp. 193-199
    • Carrano, A.C.1    Eytan, E.2    Hershko, A.3    Pagano, M.4


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