Optimizing the refolding conditions of self-assembling polypeptide nanoparticles that serve as repetitive antigen display systems

Journal of Structural Biology

Volumn 177, Issue 1, 2012, Pages 168-176

  Yang, Yongkun ^a   Ringler, Philippe ^b   Müller, Shirley A ^b   Burkhard, Peter ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Coiled coils; Mass measurement; Peptide nanoparticles; Protein folding; Scanning transmission electron microscopy; Self assembly

Indexed keywords

ALANINE; ANTIGEN; CYSTEINE; GLYCEROL; NANOPARTICLE; POLYPEPTIDE; SELF ASSEMBLING POLYPEPTIDE NANOPARTICLE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VACCINE;

ARTICLE; CELL DENSITY; CIRCULAR DICHROISM; COILED BODY; CONCENTRATION (PARAMETERS); DISPLAY SYSTEM; IONIC STRENGTH; LIGHT SCATTERING; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN REFOLDING; PROTEIN STRUCTURE; SCANNING TRANSMISSION ELECTRON MICROSCOPY; TEMPERATURE; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; ANTIGENS; CIRCULAR DICHROISM; EPITOPES, B-LYMPHOCYTE; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NANOPARTICLES; PARTICLE SIZE; PEPTIDES; PROTEIN REFOLDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84855849895     PISSN: 10478477     EISSN: 10958657     Source Type: Journal    
DOI: 10.1016/j.jsb.2011.11.011     Document Type: Article

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