The coiled-coil trigger site of the rod domain of cortexillin I unveils a distinct network of interhelical and intrahelical salt bridges

Structure

Volumn 8, Issue 3, 2000, Pages 223-230

  Burkhard, Peter ^a   Kammerer, Richard A ^a   Steinmetz, Michel O ^a   Bourenkov, Gleb P ^b   Aebi, Ueli ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

Author keywords

Coiled coil; Cortexillin I; Dimerization; Protein design; Trigger site

Indexed keywords

LEUCINE ZIPPER PROTEIN; PROTEIN DERIVATIVE; PROTEIN SUBUNIT;

ARTICLE; CRYSTAL STRUCTURE; DICTYOSTELIUM DISCOIDEUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE;

DICTYOSTELIUM DISCOIDEUM; PROTOZOA;

EID: 0034653908     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00100-3     Document Type: Article

References (38)

1. Lupas A. Coiled coils: new structures and new functions. Trends Biochem. Sci. 21:1996;375-382.
2. Kammerer R.A. Alpha-helical coiled-coil oligomerization domains in extracellular proteins. Matrix Biol. 15:1997;555-565. discussion 567-558.
3. Kohn W.D., Mant C.T., Hodges R.S. Alpha-helical protein assembly motifs. J. Biol. Chem. 272:1997;2583-2586.
4. Cohen C., Parry D.A. Alpha-helical coiled coils and bundles: how to design an alpha-helical protein. Proteins. 7:1990;1-15.
5. Crick F.C.H. The packing of α-helices: simple coiled coils. Acta Crystallogr. 6:1953;689-697.
6. Glover J.N., Harrison S.C. Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature. 373:1995;257-261.
7. Phillips G.N. Jr., Fillers J.P., Cohen C. Tropomyosin crystal structure and muscle regulation. J. Mol. Biol. 192:1986;111-131.
8. Faix J., Gerisch G.et al. Cortexillins, major determinants of cell shape and size, are actin-bundling proteins with a parallel coiled-coil tail. Cell. 86:1996;631-642.
9. Trybus K.M., Freyzon Y., Faust L.Z., Sweeney H.L. Spare the rod, spoil the regulation: necessity for a myosin rod. Proc. Natl Acad. Sci. USA. 94:1997;48-52.
10. Tripet B., Vale R.D., Hodges R.S. Demonstration of coiled-coil interactions within the kinesin neck region using synthetic peptides. Implications for motor activity. J. Biol. Chem. 272:1997;8946-8956.
11. Steinmetz M.O., Kammerer R.A.et al. A distinct 14 residue site triggers coiled-coil formation in cortexillin I. EMBO J. 17:1998;1883-1891.
12. Turbedsky K., Pollard T.D. Structural properties of the myosin-II coiled-coil assembly domain. Mol. Biol. Cell. 9:1998;144a.
13. Kammerer R.A., Steinmetz M.O.et al. An autonomous folding unit mediates the assembly of two-stranded coiled coils. Proc. Natl. Acad. Sci. USA. 95:1998;13419-13424.
14. Burkhard P., Kammerer R.A.et al. Crystallization and preliminary X-Ray diffraction analysis of the 190-A- long coiled-coil dimerization domain of the actin-bundling protein cortexillin I from Dictyostelium discoideum. J. Struct. Biol. 122:1998;293-296.
15. Harbury P.B., Kim P.S., Alber T. Crystal structure of an isoleucine-zipper trimer. Nature. 371:1994;80-83.
16. Woolfson D.N., Alber T. Predicting oligomerization states of coiled coils. Protein Sci. 4:1995;1596-1607.
17. McLachlan A.D., Stewart M. Tropomyosin coiled-coil interactions: evidence for an unstaggered structure. J. Mol. Biol. 98:1975;293-304.
18. Parry D.A., Crewther W.G., Fraser R.D., MacRae T.P. Structure of alpha-keratin: structural implication of the amino acid sequences of the type I and type II chain segments. J. Mol. Biol. 113:1977;449-454.
19. Musafia B., Buchner V., Arad D. Complex salt bridges in proteins: statistical analysis of structure and function. J. Mol. Biol. 254:1995;761-770.
20. Fagain C.O. Understanding and increasing protein stability. Biochim Biophys. Acta. 1252:1995;1-14.
21. Spek E.J., Bui A.H., Lu M., Kallenbach N.R. Surface salt bridges stabilize the GCN4 leucine zipper. Protein Sci. 7:1998;2431-2437.
22. Kozielski F., Mandelkow E.et al. The crystal structure of dimeric kinesin and implications for microtubule-dependent motility. Cell. 91:1997;985-994.
23. Lavigne P., Crump M.P, Gagne S.M., Hodges R.S., Kay C.M., Sykes B.D. Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipper. J. Mol. Biol. 281:1998;165-181.
24. Lavigne P., Kay C.M.et al. Preferential heterodimeric parallel coiled-coil formation by synthetic Max and c-Myc leucine zippers: a description of putative electrostatic interactions responsible for the specificity of heterodimerization. J. Mol. Biol. 254:1995;505-520.
25. Zhou N.E., Kay C.M., Hodges R.S. The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability. Protein Eng. 7:1994;1365-1372.
26. Lumb K.J., Kim P.S. Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper. Science. 268:1995;436-439.
27. Lavigne P., Soennichsen F.D., Kay C.M., Hodges R.S. Interhelical salt bridges, coiled-coil stability, and specificity of dimerization. Science. 271:1996;1136-1137.
28. Lumb K.J., Kim P.S. Interhelical salt bridges, coiled-coil stability, and specificity of dimerization. Science. 271:1996;1137-1138.
29. Hodges R.S. Boehringer Mannheim award lecture 1995. La conference Boehringer Mannheim 1995. De novo design of alpha-helical proteins: basic research to medical applications. Biochem. Cell Biol. 74:1996;133-154.
30. Otwinowski Z., Minor W. Processing of X-ray diffraction data collected in oscillation mode. Carter J.C.W. Methods in Enzymology, vol. 277 Part A. 1997;Academic Press, San Diego.
31. Leslie A.G.W. MOSFLM users guide. 1994;MRC-LMB, Cambridge, UK.
32. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D. 50:1994;760-763.
33. De La Fortelle E., Bricogne G. Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods. Carter J.C.W. Methods Enzymol., vol. 277 Part A. 1997;Academic Press, San Diego.
34. Zhang K.Y.J., Main P. The use of Sayre's equation with solvent flattening and histogram matching for phase extension and refinement of protein structures. Acta Crystallogr. A. 46:1990;377-381.
35. Jones T.A., Zou J.Y., Cowan S.W., Kjeldgaard M. Improved methods for binding protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A. 47:1991;110-119.
36. Brünger A.T., Warren G.L.et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54:1998;905-921.
37. Harbury P.B., Zhang T., Kim P.S., Alber T. A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants. Science. 262:1993;1401-1407.
38. O'Shea E.K., Klemm J.D., Kim P.S., Alber T. X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science. 254:1991;539-544.