Fluoxetine counteracts the cognitive and cellular effects of 5-Fluorouracil in the rat hippocampus by a mechanism of prevention rather than recovery

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Lyons, Laura ^a   ELBeltagy, Maha ^b   Bennett, Geoffrey ^a   Wigmore, Peter ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b MENOUFIA UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; FLUOXETINE; SODIUM CHLORIDE; ANTIDEPRESSANT AGENT; ANTINEOPLASTIC ANTIMETABOLITE; BROXURIDINE; KI 67 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN CELL; BRAIN PROTECTION; CELL PROLIFERATION; CELL SURVIVAL; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFECT; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MENTAL TASK; MENTAL TEST; NONHUMAN; RAT; RECOGNITION; SPATIAL MEMORY; TREATMENT DURATION; TREATMENT RESPONSE; ANIMAL; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; DEPTH PERCEPTION; DRINKING; MEMORY; METABOLISM; PATHOLOGY; TIME; WEIGHT GAIN;

RATTUS; RODENTIA;

ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; ANTIMETABOLITES, ANTINEOPLASTIC; BODY WEIGHT; BROMODEOXYURIDINE; CELL PROLIFERATION; COGNITION DISORDERS; DENTATE GYRUS; DRINKING; FLUOROURACIL; FLUOXETINE; HIPPOCAMPUS; KI-67 ANTIGEN; MALE; MEMORY; RATS; SPACE PERCEPTION; TIME FACTORS; WEIGHT GAIN;

EID: 84855849851     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030010     Document Type: Article

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