-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
R. Stupp, W.P. Mason, and M.J. van den Bent Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 2005 987 996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
2
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
R. Stupp, M.E. Hegi, and W.P. Mason Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial Lancet Oncol 10 2009 459 466
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
-
3
-
-
0030929137
-
Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: A randomized double-blind study
-
discussion 48-49
-
S. Valtonen, U. Timonen, and P. Toivanen Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: A randomized double-blind study Neurosurgery 41 1997 44 48 discussion 48-49
-
(1997)
Neurosurgery
, vol.41
, pp. 44-48
-
-
Valtonen, S.1
Timonen, U.2
Toivanen, P.3
-
4
-
-
0037384037
-
A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
-
M. Westphal, D.C. Hilt, and E. Bortey A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma Neuro Oncol 5 2003 79 88
-
(2003)
Neuro Oncol
, vol.5
, pp. 79-88
-
-
Westphal, M.1
Hilt, D.C.2
Bortey, E.3
-
5
-
-
33644787355
-
Gliadel wafer in initial surgery for malignant glioma: Long-term follow-up of a multicenter controlled trial
-
discussion 275
-
M. Westphal, Z. Ram, and V. Riddle Gliadel wafer in initial surgery for malignant glioma: Long-term follow-up of a multicenter controlled trial Acta Neurochir (Wien) 148 2006 269 275 discussion 275
-
(2006)
Acta Neurochir (Wien)
, vol.148
, pp. 269-275
-
-
Westphal, M.1
Ram, Z.2
Riddle, V.3
-
6
-
-
0028917333
-
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group
-
H. Brem, S. Piantadosi, and P.C. Burger Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group Lancet 345 1995 1008 1012
-
(1995)
Lancet
, vol.345
, pp. 1008-1012
-
-
Brem, H.1
Piantadosi, S.2
Burger, P.C.3
-
7
-
-
0027389182
-
Interstitial chemotherapy of the 9L gliosarcoma: Controlled release polymers for drug delivery in the brain
-
R.J. Tamargo, J.S. Myseros, and J.I. Epstein Interstitial chemotherapy of the 9L gliosarcoma: Controlled release polymers for drug delivery in the brain Cancer Res 53 1993 329 333
-
(1993)
Cancer Res
, vol.53
, pp. 329-333
-
-
Tamargo, R.J.1
Myseros, J.S.2
Epstein, J.I.3
-
8
-
-
0028245292
-
Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain
-
A.J. Domb, M. Rock, and J. Schwartz Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain Biomaterials 15 1994 681 688
-
(1994)
Biomaterials
, vol.15
, pp. 681-688
-
-
Domb, A.J.1
Rock, M.2
Schwartz, J.3
-
9
-
-
0029884848
-
Chemotherapeutic drugs released from polymers: Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain
-
L.K. Fung, M. Shin, and B. Tyler Chemotherapeutic drugs released from polymers: Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain Pharm Res 13 1996 671 682
-
(1996)
Pharm Res
, vol.13
, pp. 671-682
-
-
Fung, L.K.1
Shin, M.2
Tyler, B.3
-
10
-
-
0037005988
-
Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma
-
M. Esteller, G. Gaidano, and S.N. Goodman Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma J Natl Cancer Inst 94 2002 26 32
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 26-32
-
-
Esteller, M.1
Gaidano, G.2
Goodman, S.N.3
-
11
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
M. Esteller, S.R. Hamilton, and P.C. Burger Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia Cancer Res 59 1999 793 797
-
(1999)
Cancer Res
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
-
12
-
-
19244370208
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
-
M. Esteller, M. Toyota, and M. Sanchez-Cespedes Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis Cancer Res 60 2000 2368 2371
-
(2000)
Cancer Res
, vol.60
, pp. 2368-2371
-
-
Esteller, M.1
Toyota, M.2
Sanchez-Cespedes, M.3
-
13
-
-
2442659387
-
Abbreviated course of radiation therapy in older patients with glioblastoma multiforme: A prospective randomized clinical trial
-
W. Roa, P.M. Brasher, and G. Bauman Abbreviated course of radiation therapy in older patients with glioblastoma multiforme: A prospective randomized clinical trial J Clin Oncol 22 2004 1583 1588
-
(2004)
J Clin Oncol
, vol.22
, pp. 1583-1588
-
-
Roa, W.1
Brasher, P.M.2
Bauman, G.3
-
14
-
-
0025281789
-
Response criteria for phase II studies of supratentorial malignant glioma
-
D.R. Macdonald, T.L. Cascino, and S.C. Schold Jr. Response criteria for phase II studies of supratentorial malignant glioma J Clin Oncol 8 1990 1277 1280
-
(1990)
J Clin Oncol
, vol.8
, pp. 1277-1280
-
-
MacDonald, D.R.1
Cascino, T.L.2
Schold, Jr.S.C.3
-
15
-
-
34548076589
-
Clinical impact of adjuvant chemotherapy in glioblastoma multiforme: A meta-analysis
-
B.M. Spiegel, E. Esrailian, and L. Laine Clinical impact of adjuvant chemotherapy in glioblastoma multiforme: A meta-analysis CNS Drugs 21 2007 775 787
-
(2007)
CNS Drugs
, vol.21
, pp. 775-787
-
-
Spiegel, B.M.1
Esrailian, E.2
Laine, L.3
-
16
-
-
0027079969
-
Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme
-
H.S. Friedman, M.E. Dolan, and R.C. Moschel Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme J Natl Cancer Inst 84 1992 1926 1931
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1926-1931
-
-
Friedman, H.S.1
Dolan, M.E.2
Moschel, R.C.3
-
17
-
-
0030479125
-
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
-
L. Liu, S. Markowitz, and S.L. Gerson Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea Cancer Res 56 1996 5375 5379
-
(1996)
Cancer Res
, vol.56
, pp. 5375-5379
-
-
Liu, L.1
Markowitz, S.2
Gerson, S.L.3
-
18
-
-
0029662166
-
3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity
-
S.R. Wedge, J.K. Porteous, and E.S. Newlands 3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity Br J Cancer 74 1996 1030 1036
-
(1996)
Br J Cancer
, vol.74
, pp. 1030-1036
-
-
Wedge, S.R.1
Porteous, J.K.2
Newlands, E.S.3
-
19
-
-
0028026692
-
Preclinical antitumor activity of temozolomide in mice: Efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1- nitrosourea
-
J. Plowman, W.R. Waud, and A.D. Koutsoukos Preclinical antitumor activity of temozolomide in mice: Efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea Cancer Res 54 1994 3793 3799
-
(1994)
Cancer Res
, vol.54
, pp. 3793-3799
-
-
Plowman, J.1
Waud, W.R.2
Koutsoukos, A.D.3
-
20
-
-
44649084230
-
A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients
-
E. Pan, S.B. Mitchell, and J.S. Tsai A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients J Neurooncol 88 2008 353 357
-
(2008)
J Neurooncol
, vol.88
, pp. 353-357
-
-
Pan, E.1
Mitchell, S.B.2
Tsai, J.S.3
-
21
-
-
84855823220
-
Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme
-
M.J. McGirt, K.D. Than, and J.D. Weingart Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme J Neurosurg 2008
-
(2008)
J Neurosurg
-
-
McGirt, M.J.1
Than, K.D.2
Weingart, J.D.3
-
22
-
-
0028089215
-
Early postoperative magnetic resonance imaging after resection of malignant glioma: Objective evaluation of residual tumor and its influence on regrowth and prognosis
-
discussion 60-41
-
F.K. Albert, M. Forsting, and K. Sartor Early postoperative magnetic resonance imaging after resection of malignant glioma: Objective evaluation of residual tumor and its influence on regrowth and prognosis Neurosurgery 34 1994 45 60 discussion 60-41
-
(1994)
Neurosurgery
, vol.34
, pp. 45-60
-
-
Albert, F.K.1
Forsting, M.2
Sartor, K.3
-
23
-
-
0037403996
-
Temozolomide as an alternative to irradiation for elderly patients with newly diagnosed malignant gliomas
-
M. Glantz, M. Chamberlain, and Q. Liu Temozolomide as an alternative to irradiation for elderly patients with newly diagnosed malignant gliomas Cancer 97 2003 2262 2266
-
(2003)
Cancer
, vol.97
, pp. 2262-2266
-
-
Glantz, M.1
Chamberlain, M.2
Liu, Q.3
-
25
-
-
45249086059
-
Acute toxicity analysis of patients receiving surgery, Gliadel wafer implantation, and postoperative daily temozolomide with radiation therapy for primary high-grade glioma
-
(abstract)
-
C.R. Heery, A. Desjardins, and J.A. Quinn Acute toxicity analysis of patients receiving surgery, Gliadel wafer implantation, and postoperative daily temozolomide with radiation therapy for primary high-grade glioma J Clin Oncol 24 2006 11504 (abstract)
-
(2006)
J Clin Oncol
, vol.24
, pp. 11504
-
-
Heery, C.R.1
Desjardins, A.2
Quinn, J.A.3
-
26
-
-
36448938519
-
A phase II study of radiation with concomitant and then sequential temozolomide (TMZ) in patients with newly diagnosed supratentorial high-grade malignant glioma who have undergone surgery with carmustine (BCNU) wafer insertion
-
(abstract)
-
R.V. La Rocca, J. Hodes, and W.G. Villanueva A phase II study of radiation with concomitant and then sequential temozolomide (TMZ) in patients with newly diagnosed supratentorial high-grade malignant glioma who have undergone surgery with carmustine (BCNU) wafer insertion Neuro-oncol 8 2006 391 500 (abstract)
-
(2006)
Neuro-oncol
, vol.8
, pp. 391-500
-
-
La Rocca, R.V.1
Hodes, J.2
Villanueva, W.G.3
-
27
-
-
1942469956
-
MGMT: Its role in cancer aetiology and cancer therapeutics
-
S.L. Gerson MGMT: Its role in cancer aetiology and cancer therapeutics Nat Rev Cancer 4 2004 296 307
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 296-307
-
-
Gerson, S.L.1
-
28
-
-
34447314728
-
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
-
B. Kaina, M. Christmann, and S. Naumann MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents DNA Repair (Amst) 6 2007 1079 1099
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 1079-1099
-
-
Kaina, B.1
Christmann, M.2
Naumann, S.3
-
29
-
-
75149166496
-
MGMT promoter methylation in malignant gliomas: Ready for personalized medicine?
-
M. Weller, R. Stupp, and G. Reifenberger MGMT promoter methylation in malignant gliomas: Ready for personalized medicine? Nat Rev Neurol 6 2010 39 51
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 39-51
-
-
Weller, M.1
Stupp, R.2
Reifenberger, G.3
-
30
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
M.E. Hegi, A.C. Diserens, and T. Gorlia MGMT gene silencing and benefit from temozolomide in glioblastoma N Engl J Med 352 2005 997 1003
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
31
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
W. Wick, C. Hartmann, and C. Engel NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide J Clin Oncol 27 2009 5874 5880
-
(2009)
J Clin Oncol
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
-
32
-
-
73349121355
-
MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: A report from EORTC Brain Tumor Group Study 26951
-
M.J. van den Bent, H.J. Dubbink, and M. Sanson MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: A report from EORTC Brain Tumor Group Study 26951 J Clin Oncol 27 2009 5881 5886
-
(2009)
J Clin Oncol
, vol.27
, pp. 5881-5886
-
-
Van Den Bent, M.J.1
Dubbink, H.J.2
Sanson, M.3
-
33
-
-
18044402671
-
Phase i study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas
-
S. Gururangan, L. Cokgor, and J.N. Rich Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas Neuro Oncol 3 2001 246 250
-
(2001)
Neuro Oncol
, vol.3
, pp. 246-250
-
-
Gururangan, S.1
Cokgor, L.2
Rich, J.N.3
-
34
-
-
67649365700
-
Treatment of adults with newly diagnosed glioblastoma with surgery, Gliadel wafers and limited field radiation plus concomitant temozolomide followed by adjuvant temozolomide
-
(abstract)
-
T. Ryken, T. Carlisle, and J. Buatti Treatment of adults with newly diagnosed glioblastoma with surgery, Gliadel wafers and limited field radiation plus concomitant temozolomide followed by adjuvant temozolomide J Clin Oncol 26 2008 13003 (abstract)
-
(2008)
J Clin Oncol
, vol.26
, pp. 13003
-
-
Ryken, T.1
Carlisle, T.2
Buatti, J.3
|