Erratum: Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine (Journal of Medicinal Chemistry (2012) 55 (291-296) DOI: 10.1021/jm201214d);Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine

Journal of Medicinal Chemistry

Volumn 55, Issue 1, 2012, Pages 291-296

  Slack, Rachel D ^a   Mott, Bryan T ^a   Woodard, Lauren E ^a   Triphati, Abhai ^b   Sullivan, David ^b   Nenortas, Elizabeth ^c   Girdwood, Sonya C T ^c   Shapiro, Theresa A ^b,c   Posner, Gary H ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 FLUOROANILIDE; 3 METHYLTHIOETHER 3 ARTESANILIDE; 3,5 ARTESANILIDE; 4 ARTESANILIDE; ANILIDE; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ; ARTEMISONE; BENFLUMETOL; MEFLOQUINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; BEHAVIOR; CONTROLLED STUDY; MALARIA; MALE; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; SYNTHESIS; WEIGHT GAIN;

EID: 84855834219     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300104m     Document Type: Erratum

References (23)

1. Olliaro, P. L.; Boland, P. B. Clinical Public Health Implications of Antimalarial Drug Resistance. In Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery; Rosenthal, P. J., Ed.; Humana Press: Totowa, NJ, 2001; pp 65-83.
2. Guidelines for the Treatment of Malaria; World Health Organization: Geneva, 2006.
3. Ashley, E. A.; White, N. J. Artemisinin-based Combinations Curr.Opin. Infect. Dis. 2005, 18, 531-536
4. Adjuik, M.; Babiker, A.; Garner, P.; Olliaro, P.; Taylor, W.; White, N. Artesunate Combinations for Treatment of Malaria: Meta-Analysis Lancet 2004, 363, 9-17
5. Guthmann, J.-P.; Cohuet, S.; Rigutto, C.; Fortes, F.; Saraiva, N.; Kiguli, J.; Kyomuhendo, J.; Francis, M.; Noel, F.; Mulemba, M.; Balkan, S. High Efficacy of Two Artemisinin-Based Combinations (Artesunate plus Amodiaquine and Artemether plus Lumefantrine) in Caala, Central Angola Am. J. Trop. Med. Hyg. 2006, 75, 143-145
6. Myint, H. Y.; Ashley, E. A.; Day, N. P. J; Nosten, F.; White, N. J. Efficacy and Safety of Dihydroartemisinin-Piperaquine Trans. R. Soc. Trop. Med. Hyg. 2007, 101, 858-866
7. Sirima, S. B.; Tiono, A. B.; Gansane, A.; Diarra, A.; Ouedraogo, A.; Konate, A. T.; Kiechel, J. R.; Morgan, C. C.; Olliaro, P. L.; Taylor, W. R. J. The Efficacy and Safety of a New Fixed-Dose Combination of Amodiaquine and Artesunate in Young African Children with Acute Uncomplicated Plasmodium falciparum Malar. J. 2009, 8, 48
8. de Pilla Varotti, F.; Botelho, A. C. C.; Andrade, A. A.; de Paula, R. C.; Fagundes, E. M. S.; Valverde, A.; Mayer, L. M. U.; Mendonca, J. S.; de Souza, M. V. N.; Boechat, N.; Krettli, A. U. Synthesis, Antimalarial Activity, and Intracellular Targets of MEFAS, a New Hybrid Compound Derived from Mefloquine and Artesunate Antimicrob. Agents Chemother. 2008, 52, 3868-3874
9. Sagara, I.; Diallo, A. D.; Kone, M.; Coulibaly, M.; Diawara, S. I.; Guindo, O.; Maiga, H.; Niambele, M. B.; Sissoko, M.; Dicko, A.; Djimde, A.; Doumbo, O. K. A Randomized Trial of Artesunate-mefloquine versus Artemether-lumefantrine for Treatment of Uncomplicated Plasmodium falciparum Malaria in Mali Am. J. Trop. Med. Hyg. 2008, 79, 655-661
10. Bhatt, K. M.; Samia, B. M.; Bhatt, S. M.; Wasunna, K. M. Efficacy and Safety of an Artesunate/Mefloquine Combination (Artequin) in the Treatment of Uncomplicated P. falciparum Malaria in Kenya East Afr. Med. J. 2006, 83, 236-242
11. Menan, H.; Faye, O.; Same-Ekobo, A.; Oga, A. S. S.; Faye, B.; Barro, C. P. K; Kuete, T.; Ndiaye, J. L.; Vicky, A. H.; Tine, R.; Yavo, W.; Kane, D.; Kassi, K. F.; Kone, M. Comparative Study of the Efficacy and Tolerability of Dihydroartemisinin-Piperaquine-Trimethoprim versus Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium falciparum Malaria in Cameroon, Ivory Coast and Senegal Malar. J. 2011, 10, 185-193
12. Charman, S. A.; Arbe-Barnes, S.; Bathurst, I. C.; Brun, R.; Campbell, M.; Charman, W. N.; Chiu, F. C. K.; Chollet, J.; Craft, J. C.; Creek, D. J.; Dong, Y.; Matile, H.; Maurer, M.; Morizzi, J.; Nguyen, T.; Papastogiannidis, P.; Scheurer, C.; Shackleford, D. M.; Sriraghavan, K.; Stingelin, L.; Tang, Y.; Urwyler, H.; Wang, X.; White, K. L.; Wittlin, S.; Zhou, L.; Vennerstrom, J. L. Synthetic Ozonide Drug Candidate OZ439 Offers New Hope for a Single-Dose Cure of Uncomplicated Malaria Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 4400-4405
13. Rosenthal, A. S.; Chen, X.; Liu, J. O.; West, D. C.; Hergenrother, P. J.; Shapiro, T. A.; Posner, G. H. Malaria-Infected Mice Are Cured by a Single Oral Dose of New Dimeric Trioxane Sulfones Which Are Also Selectively and Powerfully Cytotoxic to Cancer Cells J. Med. Chem. 2009, 52, 1198-1203
14. Moon, D. K.; Tripathi, A.; Sullivan, D.; Siegler, M. A.; Parkin, S.; Posner, G. H. A Single, Low, Oral Dose of a 5-Carbon-Linked Trioxane Dimer Orthoester plus Mefloquine Cures Malaria-Infected Mice Bioorg. Med. Chem. Lett. 2011, 21, 2773-2775
15. Woodard, L. E.; Chang, W.; Chen, X.; Liu, J. O.; Shapiro, T. A.; Posner, G. H. Malaria-Infected Mice Live until at Least Day 30 after a New Monomeric Trioxane Combined with Mefloquine Are Administered Together in a Single Low Oral Dose J. Med. Chem. 2009, 52, 7458-7462
16. Posner, G. H.; Paik, I.-H.; Sur, S.; McRiner, A. J.; Borstnik, K.; Xie, S.; Shapiro, T. A. Orally Active, Antimalarial, Anticancer, Artemisinin-Derived Trioxane Dimers with High Stability and Efficacy J. Med. Chem. 2003, 46, 1060-1065
17. Tohma, H.; Takizawa, S.; Watanabe, H; Fukuoka, Y.; Maegawa, T.; Kita, Y. Hypervalent Iodine(V)-Induced Asymmetric Oxidation of Sulfides to Sulfoxides Mediated by Reversed Micelles: Novel Nonmetallic Catalytic System J. Org. Chem. 1999, 64, 3519-3523
18. Haynes, R. K.; Fugmann, B.; Stetter, J.; Rieckmann, K.; Heilmann, H.-D.; Chan, H.-W.; Cheung, M.-K.; Lam, W.-L.; Wong, H.-N.; Croft, S. L.; Vivas, L.; Rattray, L.; Stewart, L.; Peters, W.; Robinson, B. L.; Edstein, M. D.; Kotecka, B.; Kyle, D. E.; Beckermann, B.; Gerisch, M.; Radtke, M.; Schmuck, G.; Steinke, W.; Wollborn, U.; Schmeer, K.; Römer, A. Artemisone-A Highly Active Antimalarial Drug of the Artemisinin Class Angew. Chem., Int. Ed. 2006, 45, 2082-2088
19. Posner, G. H.; ODowd, H.; Caferro, T.; Cumming, J. N.; Ploypradith, P.; Xie, S.; Shapiro, T. A. Antimalarial Synthetic Sulfone Trioxanes Tetrahedron Lett. 1998, 39, 2273-2276
20. Bachi, M. D.; Korshin, E. E.; Hoos, R.; Szpilman, A. M.; Ploypradith, P.; Xie, S.; Shapiro, T. A.; Posner, G. H. A Short Synthesis and Biological Evaluation of Potent and Nontoxic Antimalarial Bridged Bicyclic β-Sulfonyl-Endoperoxides J. Med. Chem. 2003, 46, 2516-2533
21. Amewu, R.; Gibbon, P.; Mukhtar, A.; Stachulski, A. V.; Ward, S. A.; Hall, C.; Rimmer, K.; Davies, J.; Vivas, L.; Bacsa, J.; Mercer, A. E.; Nixon, G.; Stocks, P. A.; ONeill, P. M. Synthesis, in Vitro and in Vivo Antimalarial Assessment of Sulfide, Sulfone and Vinyl Amide-Substituted 1,2,4-Trioxanes Prepared via Thiol-Olefin Co-Oxygenation (TOCO) of Allylic Alcohols Org. Biomol. Chem. 2010, 8, 2068-2077
22. Jung, M.; Tak, J.; Chung, W.-Y.; Park, K.-K. Antiangiogenic Activity of Deoxoartemisinin Derivatives on Chorioallantoic Membrane Bioorg. Med. Chem. Lett. 2006, 16, 1227-1230
23. Burrows, N. J.; Chibale, K.; Wells, T. N. C. The State of the Art in Anti-Malarial Drug Discovery and Development Curr. Top. Med. Chem. 2011, 11, 1226-1254