메뉴 건너뛰기




Volumn 7, Issue 1, 2012, Pages

Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CELL SURFACE MARKER; KINESIN 1; TAU PROTEIN; KINESIN LIGHT CHAIN PROTEINS; KINESIN LIGHT-CHAIN PROTEINS; MAPT PROTEIN, HUMAN; MEMBRANE ANTIGEN; MICROTUBULE ASSOCIATED PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; POU5F1 PROTEIN, HUMAN; TRA 1 81 ANTIGEN, HUMAN; TRA-1-81 ANTIGEN, HUMAN;

EID: 84855830665     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029755     Document Type: Article
Times cited : (8)

References (49)
  • 1
    • 0022385727 scopus 로고
    • Identification of a Novel Force-Generating Protein, Kinesin, Involved in Microtubule-Based Motility
    • Vale RD, Reese TS, Sheetz MP, (1985) Identification of a Novel Force-Generating Protein, Kinesin, Involved in Microtubule-Based Motility. Cell 42: 39-50.
    • (1985) Cell , vol.42 , pp. 39-50
    • Vale, R.D.1    Reese, T.S.2    Sheetz, M.P.3
  • 2
    • 0021808444 scopus 로고
    • A novel brain ATPase with properties expected for the fast axonal transport motor
    • Brady ST, (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317: 73-75.
    • (1985) Nature , vol.317 , pp. 73-75
    • Brady, S.T.1
  • 3
    • 0024591237 scopus 로고
    • Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration
    • doi:10.1016/0092-8674(89)90691-0
    • Hirokawa N, Pfister KK, Yorifuji H, Wagner MC, Brady ST, et al. (1989) Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration. Cell 56: 867-878 doi:10.1016/0092-8674(89)90691-0.
    • (1989) Cell , vol.56 , pp. 867-878
    • Hirokawa, N.1    Pfister, K.K.2    Yorifuji, H.3    Wagner, M.C.4    Brady, S.T.5
  • 4
    • 0028363485 scopus 로고
    • Cloning and localization of a conventional kinesin motor expressed exclusively in neurons
    • Niclas J, Navone F, Hom-Booher N, Vale RD, (1994) Cloning and localization of a conventional kinesin motor expressed exclusively in neurons. Neuron 12: 1059-1072.
    • (1994) Neuron , vol.12 , pp. 1059-1072
    • Niclas, J.1    Navone, F.2    Hom-Booher, N.3    Vale, R.D.4
  • 5
    • 0027755695 scopus 로고
    • Cloning and genetic characterization of the human kinesin light-chain (KLC) gene
    • Cabeza-Arvelaiz Y, Shih LC, Hardman N, Asselbergs F, Bilbe G, et al. (1993) Cloning and genetic characterization of the human kinesin light-chain (KLC) gene. DNA Cell Biol 12: 881-892.
    • (1993) DNA Cell Biol , vol.12 , pp. 881-892
    • Cabeza-Arvelaiz, Y.1    Shih, L.C.2    Hardman, N.3    Asselbergs, F.4    Bilbe, G.5
  • 6
    • 0030585760 scopus 로고    scopus 로고
    • Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes
    • doi:10.1006/geno.1996.0303
    • Lamerdin JE, Stilwagen SA, Ramirez MH, Stubbs L, Carrano AV, (1996) Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes. Genomics 34: 399-409 doi:10.1006/geno.1996.0303.
    • (1996) Genomics , vol.34 , pp. 399-409
    • Lamerdin, J.E.1    Stilwagen, S.A.2    Ramirez, M.H.3    Stubbs, L.4    Carrano, A.V.5
  • 7
    • 0032169075 scopus 로고    scopus 로고
    • Chromosomal localization reveals three kinesin heavy chain genes in mouse
    • doi:10.1006/geno.1998.5427
    • Xia C, Rahman A, Yang Z, Goldstein LS, (1998) Chromosomal localization reveals three kinesin heavy chain genes in mouse. Genomics 52: 209-213 doi:10.1006/geno.1998.5427.
    • (1998) Genomics , vol.52 , pp. 209-213
    • Xia, C.1    Rahman, A.2    Yang, Z.3    Goldstein, L.S.4
  • 8
    • 0032546953 scopus 로고    scopus 로고
    • Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins
    • Rahman A, Friedman DS, Goldstein LS, (1998) Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins. J Biol Chem 273: 15395-15403.
    • (1998) J Biol Chem , vol.273 , pp. 15395-15403
    • Rahman, A.1    Friedman, D.S.2    Goldstein, L.S.3
  • 9
    • 0034279183 scopus 로고    scopus 로고
    • KIF5C, a Novel Neuronal Kinesin Enriched in Motor Neurons
    • Kanai Y, Okada Y, Tanaka Y, Harada A, Terada S, et al. (2000) KIF5C, a Novel Neuronal Kinesin Enriched in Motor Neurons. J Neurosci 20: 6374-6384.
    • (2000) J Neurosci , vol.20 , pp. 6374-6384
    • Kanai, Y.1    Okada, Y.2    Tanaka, Y.3    Harada, A.4    Terada, S.5
  • 10
    • 0032568790 scopus 로고    scopus 로고
    • Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria
    • Tanaka Y, Kanai Y, Okada Y, Nonaka S, Takeda S, et al. (1998) Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell 93: 1147-1158.
    • (1998) Cell , vol.93 , pp. 1147-1158
    • Tanaka, Y.1    Kanai, Y.2    Okada, Y.3    Nonaka, S.4    Takeda, S.5
  • 11
    • 65949098412 scopus 로고    scopus 로고
    • Axonal Stress Kinase Activation and Tau Misbehavior Induced by Kinesin-1 Transport Defects
    • doi:10.1523/JNEUROSCI.0780-09.2009
    • Falzone TL, Stokin GB, Lillo C, Rodrigues EM, Westerman EL, et al. (2009) Axonal Stress Kinase Activation and Tau Misbehavior Induced by Kinesin-1 Transport Defects. J Neurosci 29: 5758-5767 doi:10.1523/JNEUROSCI.0780-09.2009.
    • (2009) J Neurosci , vol.29 , pp. 5758-5767
    • Falzone, T.L.1    Stokin, G.B.2    Lillo, C.3    Rodrigues, E.M.4    Westerman, E.L.5
  • 12
    • 0026606451 scopus 로고
    • Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides
    • Ferreira A, Niclas J, Vale RD, Banker G, Kosik KS, (1992) Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides. J Cell Biol 117: 595-606.
    • (1992) J Cell Biol , vol.117 , pp. 595-606
    • Ferreira, A.1    Niclas, J.2    Vale, R.D.3    Banker, G.4    Kosik, K.S.5
  • 13
    • 20744459425 scopus 로고    scopus 로고
    • Tubulin and CRMP-2 complex is transported via Kinesin-1
    • doi:10.1111/j.1471-4159.2005.03063.x
    • Kimura T, Watanabe H, Iwamatsu A, Kaibuchi K, (2005) Tubulin and CRMP-2 complex is transported via Kinesin-1. J Neurochem 93: 1371-1382 doi:10.1111/j.1471-4159.2005.03063.x.
    • (2005) J Neurochem , vol.93 , pp. 1371-1382
    • Kimura, T.1    Watanabe, H.2    Iwamatsu, A.3    Kaibuchi, K.4
  • 14
    • 67349200776 scopus 로고    scopus 로고
    • Tubulin tyrosination navigates the kinesin-1 motor domain to axons. Nat
    • doi:10.1038/nn.2314
    • Konishi Y, Setou M, (2009) Tubulin tyrosination navigates the kinesin-1 motor domain to axons. Nat. Neurosci 12: 559-567 doi:10.1038/nn.2314.
    • (2009) Neurosci , vol.12 , pp. 559-567
    • Konishi, Y.1    Setou, M.2
  • 15
    • 0033588989 scopus 로고    scopus 로고
    • Defective Kinesin Heavy Chain Behavior in Mouse Kinesin Light Chain Mutants
    • Rahman A, Kamal A, Roberts EA, Goldstein LSB, (1999) Defective Kinesin Heavy Chain Behavior in Mouse Kinesin Light Chain Mutants. J Cell Biol 146: 1277-1288.
    • (1999) J Cell Biol , vol.146 , pp. 1277-1288
    • Rahman, A.1    Kamal, A.2    Roberts, E.A.3    Goldstein, L.S.B.4
  • 16
    • 0026096809 scopus 로고
    • Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis
    • Saxton WM, Hicks J, Goldstein LS, Raff EC, (1991) Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis. Cell 64: 1093-1102.
    • (1991) Cell , vol.64 , pp. 1093-1102
    • Saxton, W.M.1    Hicks, J.2    Goldstein, L.S.3    Raff, E.C.4
  • 17
    • 0037437149 scopus 로고    scopus 로고
    • Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A
    • doi:10.1083/jcb.200301026
    • Xia C-H, Roberts EA, Her L-S, Liu X, Williams DS, et al. (2003) Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol 161: 55-66 doi:10.1083/jcb.200301026.
    • (2003) J Cell Biol , vol.161 , pp. 55-66
    • Xia, C.-H.1    Roberts, E.A.2    Her, L.-S.3    Liu, X.4    Williams, D.S.5
  • 18
    • 79951710366 scopus 로고    scopus 로고
    • Stable Kinesin and Dynein assemblies drive the axonal transport of Mammalian prion protein vesicles
    • doi:10.1016/j.cell.2011.01.021
    • Encalada SE, Szpankowski L, Xia C-H, Goldstein LSB, (2011) Stable Kinesin and Dynein assemblies drive the axonal transport of Mammalian prion protein vesicles. Cell 144: 551-565 doi:10.1016/j.cell.2011.01.021.
    • (2011) Cell , vol.144 , pp. 551-565
    • Encalada, S.E.1    Szpankowski, L.2    Xia, C.-H.3    Goldstein, L.S.B.4
  • 19
    • 48249102303 scopus 로고    scopus 로고
    • Role of axonal transport in neurodegenerative diseases
    • doi:10.1146/annurev.neuro.31.061307.090711
    • De Vos KJ, Grierson AJ, Ackerley S, Miller CCJ, (2008) Role of axonal transport in neurodegenerative diseases. Annu Rev Neurosci 31: 151-173 doi:10.1146/annurev.neuro.31.061307.090711.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 151-173
    • De Vos, K.J.1    Grierson, A.J.2    Ackerley, S.3    Miller, C.C.J.4
  • 20
    • 0025056563 scopus 로고
    • Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport
    • Koo EH, Sisodia SS, Archer DR, Martin LJ, Weidemann A, et al. (1990) Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proc Natl Acad Sci U S A 87: 1561-1565.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 1561-1565
    • Koo, E.H.1    Sisodia, S.S.2    Archer, D.R.3    Martin, L.J.4    Weidemann, A.5
  • 21
    • 0027215550 scopus 로고
    • Intraneuronal compartments of the amyloid precursor protein
    • Ferreira A, Caceres A, Kosik KS, (1993) Intraneuronal compartments of the amyloid precursor protein. J Neurosci 13: 3112-3123.
    • (1993) J Neurosci , vol.13 , pp. 3112-3123
    • Ferreira, A.1    Caceres, A.2    Kosik, K.S.3
  • 22
    • 0141532147 scopus 로고    scopus 로고
    • Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1
    • doi:10.1074/jbc.M304379200
    • Matsuda S, Matsuda Y, D'Adamio L, (2003) Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1. J Biol Chem 278: 38601-38606 doi:10.1074/jbc.M304379200.
    • (2003) J Biol Chem , vol.278 , pp. 38601-38606
    • Matsuda, S.1    Matsuda, Y.2    D'Adamio, L.3
  • 23
    • 0033636136 scopus 로고    scopus 로고
    • Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
    • Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS, (2000) Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 28: 449-459.
    • (2000) Neuron , vol.28 , pp. 449-459
    • Kamal, A.1    Stokin, G.B.2    Yang, Z.3    Xia, C.H.4    Goldstein, L.S.5
  • 24
    • 27844470590 scopus 로고    scopus 로고
    • Molecular motors implicated in the axonal transport of tau and {alpha}-synuclein
    • doi:10.1242/jcs.02558
    • Utton MA, Noble WJ, Hill JE, Anderton BH, Hanger DP, (2005) Molecular motors implicated in the axonal transport of tau and {alpha}-synuclein. J Cell Sci 118: 4645-4654 doi:10.1242/jcs.02558.
    • (2005) J Cell Sci , vol.118 , pp. 4645-4654
    • Utton, M.A.1    Noble, W.J.2    Hill, J.E.3    Anderton, B.H.4    Hanger, D.P.5
  • 25
    • 77958459087 scopus 로고    scopus 로고
    • Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies
    • Available:. Accessed 8 Sep 2010
    • Falzone TL, Gunawardena S, McCleary D, Reis G, Goldstein LSB, (2010) Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Hum Mol Genet Available: http://www.ncbi.nlm.nih.gov/pubmed/20817925. Accessed 8 Sep 2010.
    • (2010) Hum Mol Genet
    • Falzone, T.L.1    Gunawardena, S.2    McCleary, D.3    Reis, G.4    Goldstein, L.S.B.5
  • 26
    • 20044385920 scopus 로고    scopus 로고
    • Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease
    • doi:10.1126/science.1105681
    • Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, et al. (2005) Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease. Science 307: 1282-1288 doi:10.1126/science.1105681.
    • (2005) Science , vol.307 , pp. 1282-1288
    • Stokin, G.B.1    Lillo, C.2    Falzone, T.L.3    Brusch, R.G.4    Rockenstein, E.5
  • 27
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic Stem Cell Lines Derived from Human Blastocysts
    • doi:10.1126/science.282.5391.1145
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, et al. (1998) Embryonic Stem Cell Lines Derived from Human Blastocysts. Science 282: 1145-1147 doi:10.1126/science.282.5391.1145.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3    Waknitz, M.A.4    Swiergiel, J.J.5
  • 28
    • 33748037728 scopus 로고    scopus 로고
    • Human Embryonic Stem Cells as a Powerful Tool for Studying Human Embryogenesis
    • doi:10.1203/01.pdr.0000228349.24676.17
    • Dvash T, Ben-Yosef D, Eiges R, (2006) Human Embryonic Stem Cells as a Powerful Tool for Studying Human Embryogenesis. Pediatric Research 60: 111-117 doi:10.1203/01.pdr.0000228349.24676.17.
    • (2006) Pediatric Research , vol.60 , pp. 111-117
    • Dvash, T.1    Ben-Yosef, D.2    Eiges, R.3
  • 29
    • 79951576608 scopus 로고    scopus 로고
    • Using human pluripotent stem cells to untangle neurodegenerative disease mechanisms
    • doi:10.1007/s00018-010-0557-6
    • Malgrange B, Borgs L, Grobarczyk B, Purnelle A, Ernst P, et al. (2011) Using human pluripotent stem cells to untangle neurodegenerative disease mechanisms. Cell Mol Life Sci 68: 635-649 doi:10.1007/s00018-010-0557-6.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 635-649
    • Malgrange, B.1    Borgs, L.2    Grobarczyk, B.3    Purnelle, A.4    Ernst, P.5
  • 30
    • 3142708570 scopus 로고    scopus 로고
    • Cre-lox-regulated conditional RNA interference from transgenes
    • doi:10.1073/pnas.0403954101
    • Ventura A, Meissner A, Dillon CP, McManus M, Sharp PA, et al. (2004) Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci U S A 101: 10380-10385 doi:10.1073/pnas.0403954101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 10380-10385
    • Ventura, A.1    Meissner, A.2    Dillon, C.P.3    McManus, M.4    Sharp, P.A.5
  • 31
    • 12144288049 scopus 로고    scopus 로고
    • Derivation of embryonic stem-cell lines from human blastocysts
    • doi:10.1371/journal.pone.0017540
    • Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, et al. (2004) Derivation of embryonic stem-cell lines from human blastocysts. N Engl J Med 350: 1353-1356 doi:10.1056/NEJMsr040330.
    • (2004) N Engl J Med , vol.350 , pp. 1353-1356
    • Cowan, C.A.1    Klimanskaya, I.2    McMahon, J.3    Atienza, J.4    Witmyer, J.5
  • 32
    • 79952292990 scopus 로고    scopus 로고
    • Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells
    • doi:10.1371/journal.pone.0017540
    • Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, et al. (2011) Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS ONE 6: e17540 doi:10.1371/journal.pone.0017540.
    • (2011) PLoS ONE , vol.6
    • Yuan, S.H.1    Martin, J.2    Elia, J.3    Flippin, J.4    Paramban, R.I.5
  • 33
    • 0019954536 scopus 로고
    • Hormonal responsiveness of a preadipose cell line derived from newborn mouse calvaria
    • doi:10.1002/jcp.1041120113
    • Kodama HA, Amagai Y, Koyama H, Kasai S, (1982) Hormonal responsiveness of a preadipose cell line derived from newborn mouse calvaria. J Cell Physiol 112: 83-88 doi:10.1002/jcp.1041120113.
    • (1982) J Cell Physiol , vol.112 , pp. 83-88
    • Kodama, H.A.1    Amagai, Y.2    Koyama, H.3    Kasai, S.4
  • 34
    • 8644259350 scopus 로고    scopus 로고
    • Dopaminergic Differentiation of Human Embryonic Stem Cells
    • doi:10.1634/stemcells.22-6-925
    • Zeng X, (2004) Dopaminergic Differentiation of Human Embryonic Stem Cells. Stem Cells 22: 925-940 doi:10.1634/stemcells.22-6-925.
    • (2004) Stem Cells , vol.22 , pp. 925-940
    • Zeng, X.1
  • 35
    • 0037303676 scopus 로고    scopus 로고
    • Stable genetic modification of human embryonic stem cells by lentiviral vectors
    • Gropp M, Itsykson P, Singer O, Ben-Hur T, Reinhartz E, et al. (2003) Stable genetic modification of human embryonic stem cells by lentiviral vectors. Mol Ther 7: 281-287.
    • (2003) Mol Ther , vol.7 , pp. 281-287
    • Gropp, M.1    Itsykson, P.2    Singer, O.3    Ben-Hur, T.4    Reinhartz, E.5
  • 36
    • 53349168419 scopus 로고    scopus 로고
    • Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes
    • doi:10.1038/ncb1776
    • Satoh D, Sato D, Tsuyama T, Saito M, Ohkura H, et al. (2008) Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. Nat Cell Biol 10: 1164-1171 doi:10.1038/ncb1776.
    • (2008) Nat Cell Biol , vol.10 , pp. 1164-1171
    • Satoh, D.1    Sato, D.2    Tsuyama, T.3    Saito, M.4    Ohkura, H.5
  • 37
    • 78751564789 scopus 로고    scopus 로고
    • C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites
    • doi:10.1242/dev.060939
    • Aguirre-Chen C, Bülow HE, Kaprielian Z, (2011) C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites. Development 138: 507-518 doi:10.1242/dev.060939.
    • (2011) Development , vol.138 , pp. 507-518
    • Aguirre-Chen, C.1    Bülow, H.E.2    Kaprielian, Z.3
  • 38
    • 33745012950 scopus 로고    scopus 로고
    • Neural Subtype Specification from Embryonic Stem Cells
    • doi:10.1111/j.1750-3639.2006.00008.x
    • Zhang S-C, (2006) Neural Subtype Specification from Embryonic Stem Cells. Brain Pathology 16: 132-142 doi:10.1111/j.1750-3639.2006.00008.x.
    • (2006) Brain Pathology , vol.16 , pp. 132-142
    • Zhang, S.-C.1
  • 39
    • 74049140758 scopus 로고    scopus 로고
    • Phenotypes of stem cells from diverse origin
    • doi:10.1002/cyto.a.20844
    • Tárnok A, Ulrich H, Bocsi J, (2010) Phenotypes of stem cells from diverse origin. Cytometry A 77: 6-10 doi:10.1002/cyto.a.20844.
    • (2010) Cytometry A , vol.77 , pp. 6-10
    • Tárnok, A.1    Ulrich, H.2    Bocsi, J.3
  • 40
    • 0027723051 scopus 로고
    • Microtubule-dependent control of cell shape and pseudopodial activity is inhibited by the antibody to kinesin motor domain
    • Rodionov VI, Gyoeva FK, Tanaka E, Bershadsky AD, Vasiliev JM, et al. (1993) Microtubule-dependent control of cell shape and pseudopodial activity is inhibited by the antibody to kinesin motor domain. J Cell Biol 123: 1811-1820.
    • (1993) J Cell Biol , vol.123 , pp. 1811-1820
    • Rodionov, V.I.1    Gyoeva, F.K.2    Tanaka, E.3    Bershadsky, A.D.4    Vasiliev, J.M.5
  • 41
    • 77955438584 scopus 로고    scopus 로고
    • Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape
    • doi:10.1073/pnas.1004736107
    • Jolly AL, Kim H, Srinivasan D, Lakonishok M, Larson AG, et al. (2010) Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape. Proc Natl Acad Sci U S A 107: 12151-12156 doi:10.1073/pnas.1004736107.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 12151-12156
    • Jolly, A.L.1    Kim, H.2    Srinivasan, D.3    Lakonishok, M.4    Larson, A.G.5
  • 42
    • 0028913471 scopus 로고
    • Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons
    • Yamazaki T, Selkoe DJ, Koo EH, (1995) Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons. J Cell Biol 129: 431-442.
    • (1995) J Cell Biol , vol.129 , pp. 431-442
    • Yamazaki, T.1    Selkoe, D.J.2    Koo, E.H.3
  • 43
    • 57649221135 scopus 로고    scopus 로고
    • Amyloid Precursor Protein Trafficking, Processing, and Function
    • doi:10.1074/jbc.R800019200
    • Thinakaran G, Koo EH, (2008) Amyloid Precursor Protein Trafficking, Processing, and Function. Journal of Biological Chemistry 283: 29615-29619 doi:10.1074/jbc.R800019200.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 29615-29619
    • Thinakaran, G.1    Koo, E.H.2
  • 44
    • 0024550204 scopus 로고
    • Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein
    • doi:10.1016/0092-8674(89)90177-3
    • Weidemann A, König G, Bunke D, Fischer P, Salbaum JM, et al. (1989) Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57: 115-126 doi:10.1016/0092-8674(89)90177-3.
    • (1989) Cell , vol.57 , pp. 115-126
    • Weidemann, A.1    König, G.2    Bunke, D.3    Fischer, P.4    Salbaum, J.M.5
  • 45
    • 0033621739 scopus 로고    scopus 로고
    • Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition
    • doi:10.1038/72237
    • Iwata N, Tsubuki S, Takaki Y, Watanabe K, Sekiguchi M, et al. (2000) Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition. Nat Med 6: 143-150 doi:10.1038/72237.
    • (2000) Nat Med , vol.6 , pp. 143-150
    • Iwata, N.1    Tsubuki, S.2    Takaki, Y.3    Watanabe, K.4    Sekiguchi, M.5
  • 46
    • 0037111837 scopus 로고    scopus 로고
    • Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice
    • Lazarov O, Lee M, Peterson DA, Sisodia SS, (2002) Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice. J Neurosci 22: 9785-9793.
    • (2002) J Neurosci , vol.22 , pp. 9785-9793
    • Lazarov, O.1    Lee, M.2    Peterson, D.A.3    Sisodia, S.S.4
  • 47
    • 0034116562 scopus 로고    scopus 로고
    • Clonal tests of conventional kinesin function during cell proliferation and differentiation
    • Brendza RP, Sheehan KB, Turner FR, Saxton WM, (2000) Clonal tests of conventional kinesin function during cell proliferation and differentiation. Mol Biol Cell 11: 1329-1343.
    • (2000) Mol Biol Cell , vol.11 , pp. 1329-1343
    • Brendza, R.P.1    Sheehan, K.B.2    Turner, F.R.3    Saxton, W.M.4
  • 49
    • 0032538837 scopus 로고    scopus 로고
    • Light chain-dependent regulation of Kinesin's interaction with microtubules
    • Verhey KJ, Lizotte DL, Abramson T, Barenboim L, Schnapp BJ, et al. (1998) Light chain-dependent regulation of Kinesin's interaction with microtubules. J Cell Biol 143: 1053-1066.
    • (1998) J Cell Biol , vol.143 , pp. 1053-1066
    • Verhey, K.J.1    Lizotte, D.L.2    Abramson, T.3    Barenboim, L.4    Schnapp, B.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.