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Volumn 45, Issue 3, 2012, Pages 282-295

Soybean agglutinin coated PLA particles entrapping candidate vaccines induces enhanced primary and sustained secondary antibody response from single point immunization

Author keywords

Antibody response; DC SIGN; Dendritic cells; Lectin; Polylactide microparticles; Soybean agglutinin

Indexed keywords

ALUMINUM POTASSIUM SULFATE; DECTIN 1; DIPHTHERIA VACCINE; LECTIN RECEPTOR; POLYLACTIDE; SOYBEAN AGGLUTININ; TETANUS TOXOID;

EID: 84855784570     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.11.022     Document Type: Article
Times cited : (15)

References (59)
  • 2
    • 77955809072 scopus 로고    scopus 로고
    • N-glycan targeted gene delivery to the dendritic cell SIGN receptor
    • K. Anderson, C. Fernandez, and K.G. Rice N-glycan targeted gene delivery to the dendritic cell SIGN receptor Bioconjug. Chem. 21 2010 1479 1485
    • (2010) Bioconjug. Chem. , vol.21 , pp. 1479-1485
    • Anderson, K.1    Fernandez, C.2    Rice, K.G.3
  • 3
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • DOI 10.1038/32588
    • J. Banchereau, and R.M. Steinman Dendritic cells and the control of immunity Nature 392 1998 245 252 (Pubitemid 28155090)
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 4
    • 40649091858 scopus 로고    scopus 로고
    • Interaction of dendritic cells with biomaterials
    • DOI 10.1016/j.smim.2007.10.013, PII S1044532307000899
    • J.E. Babensee Interaction of dendritic cells with biomaterials Semin. Immunol. 20 2008 101 108 (Pubitemid 351374834)
    • (2008) Seminars in Immunology , vol.20 , Issue.2 , pp. 101-108
    • Babensee, J.E.1
  • 7
    • 1842613560 scopus 로고    scopus 로고
    • Potent, long lasting systemic antibody levels and mixed Th1/Th2 immune response after nasal immunization with malaria antigen loaded PLGA microparticles
    • DOI 10.1016/j.vaccine.2003.10.020, PII S0264410X03007679
    • A.M. Carcaboso, R.M. Hernández, M. Igartua, J.E. Rosas, M.E. Patarroyo, and J.L. Pedraz Potent, long lasting systemic antibody levels and mixed Th1/Th2 immune response after nasal immunization with malaria antigen loaded PLGA microparticles Vaccine 22 2004 1423 1432 (Pubitemid 38446918)
    • (2004) Vaccine , vol.22 , Issue.11-12 , pp. 1423-1432
    • Carcaboso, A.M.1    Hernandez, R.M.2    Igartua, M.3    Rosas, J.E.4    Patarroyo, M.E.5    Pedraz, J.L.6
  • 8
    • 0033038260 scopus 로고    scopus 로고
    • Single-administration vaccines: Controlled-release technology to mimic repeated immunizations
    • DOI 10.1016/S0167-7799(98)01272-4, PII S0167779998012724
    • J.L. Cleland Single-administration vaccines: controlled-release technology to mimic repeated immunizations Trends Biotechnol. 17 1999 25 29 (Pubitemid 29246023)
    • (1999) Trends in Biotechnology , vol.17 , Issue.1 , pp. 25-29
    • Cleland, J.L.1
  • 9
    • 77958498224 scopus 로고    scopus 로고
    • Vaccine adjuvants: Putting innate immunity to work
    • R.L. Coffman, A. Sher, and R.A. Seder Vaccine adjuvants: putting innate immunity to work Immunity 33 2010 492 502
    • (2010) Immunity , vol.33 , pp. 492-502
    • Coffman, R.L.1    Sher, A.2    Seder, R.A.3
  • 13
    • 58149085979 scopus 로고    scopus 로고
    • Influence of ligand valency on the targeting of immature human dendritic cells by mannosylated liposomes
    • S. Espuelas, C. Thumann, B. Heurtault, F. Schuber, and B. Frisch Influence of ligand valency on the targeting of immature human dendritic cells by mannosylated liposomes Bioconjug. Chem. 19 2008 2385 2393
    • (2008) Bioconjug. Chem. , vol.19 , pp. 2385-2393
    • Espuelas, S.1    Thumann, C.2    Heurtault, B.3    Schuber, F.4    Frisch, B.5
  • 14
    • 33751329788 scopus 로고    scopus 로고
    • The preservation of phenotype and functionality of dendritic cells upon phagocytosis of polyelectrolyte-coated PLGA microparticles
    • DOI 10.1016/j.biomaterials.2006.10.034, PII S014296120600946X
    • S. Fischer, E. Uetz-von Allmen, Y. Waeckerle-Men, M. Groettrup, H.P. Merkle, and B. Gander The preservation of phenotype and functionality of dendritic cells upon phagocytosis of polyelectrolyte-coated PLGA microparticles Biomaterials 28 2007 994 1004 (Pubitemid 44809435)
    • (2007) Biomaterials , vol.28 , Issue.6 , pp. 994-1004
    • Fischer, S.1    Uetz-von Allmen, E.2    Waeckerle-Men, Y.3    Groettrup, M.4    Merkle, H.P.5    Gander, B.6
  • 15
    • 0032490612 scopus 로고    scopus 로고
    • Poly(lactide-co-glycolide) microparticles for the development of single- dose controlled-release vaccines
    • DOI 10.1016/S0169-409X(98)00012-X, PII S0169409X9800012X
    • R.K. Gupta, M. Singh, and D.T. O'Hagan Poly(lactide-co-glycolide) microparticles for the development of single-dose controlled-release vaccines Adv. Drug Deliv. Rev. 32 1998 225 246 (Pubitemid 28267411)
    • (1998) Advanced Drug Delivery Reviews , vol.32 , Issue.3 , pp. 225-246
    • O'Hagan, D.T.1    Singh, M.2    Gupta, R.K.3
  • 17
    • 79251594583 scopus 로고    scopus 로고
    • Tuning the immune response of dendritic cells to surface-assembled poly(I:C) on microspheres through synergistic interactions between phagocytic and TLR3 signaling
    • A.M. Hafner, B. Corthésy, M. Textor, and H.P. Merkle Tuning the immune response of dendritic cells to surface-assembled poly(I:C) on microspheres through synergistic interactions between phagocytic and TLR3 signaling Biomaterials 32 2011 2651 2661
    • (2011) Biomaterials , vol.32 , pp. 2651-2661
    • Hafner, A.M.1    Corthésy, B.2    Textor, M.3    Merkle, H.P.4
  • 18
    • 9244253168 scopus 로고    scopus 로고
    • Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens
    • DOI 10.1016/j.addr.2004.09.003, PII S0169409X04002091
    • W. Jiang, R.K. Gupta, M.C. Deshpande, and S.P. Schwendeman Biodegradable poly (lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens Adv. Drug Deliv. Rev. 57 2005 391 410 (Pubitemid 39550967)
    • (2005) Advanced Drug Delivery Reviews , vol.57 , Issue.SPEC. ISS. 3 , pp. 391-410
    • Jiang, W.1    Gupta, R.K.2    Deshpande, M.C.3    Schwendeman, S.P.4
  • 19
    • 0034601247 scopus 로고    scopus 로고
    • Revisiting PLA/PLGA microspheres: An analysis of their potential in parenteral vaccination
    • DOI 10.1016/S0939-6411(00)00079-5, PII S0939641100000795
    • P. Johansen, Y. Men, H.P. Merkle, and B. Gander Revisiting PLA/PLGA microsphere: an analysis of their potential in parenteral vaccination Eur. J. Pharm. Biopharm. 50 2000 129 146 (Pubitemid 30326693)
    • (2000) European Journal of Pharmaceutics and Biopharmaceutics , vol.50 , Issue.1 , pp. 129-146
    • Johansen, P.1    Men, Y.2    Merkle, H.P.3    Gander, B.4
  • 21
    • 34948832042 scopus 로고    scopus 로고
    • Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response
    • DOI 10.1016/j.biomaterials.2007.08.015, PII S0142961207006448
    • V. Kanchan, and A.K. Panda Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response Biomaterials 28 2007 5344 5357 (Pubitemid 47532191)
    • (2007) Biomaterials , vol.28 , Issue.35 , pp. 5344-5357
    • Kanchan, V.1    Panda, A.K.2
  • 22
    • 67650263398 scopus 로고    scopus 로고
    • Role of alum in improving the immunogenicity of biodegradable polymer particle entrapped antigens
    • V. Kanchan, Y.K. Katare, and A.K. Panda Role of alum in improving the immunogenicity of biodegradable polymer particle entrapped antigens Eur. J. Pharm. Sci. 38 2009 18 28
    • (2009) Eur. J. Pharm. Sci. , vol.38 , pp. 18-28
    • Kanchan, V.1    Katare, Y.K.2    Panda, A.K.3
  • 23
    • 67651152577 scopus 로고    scopus 로고
    • Memory antibody response from antigen loaded polymer particles and the effect of antigen release kinetics
    • V. Kanchan, Y.K. Katare, and A.K. Panda Memory antibody response from antigen loaded polymer particles and the effect of antigen release kinetics Biomaterials 30 2009 4763 4776
    • (2009) Biomaterials , vol.30 , pp. 4763-4776
    • Kanchan, V.1    Katare, Y.K.2    Panda, A.K.3
  • 24
    • 23944462440 scopus 로고    scopus 로고
    • Influence of particle size, antigen load, dose and additional adjuvant on the immune response from antigen loaded PLA microparticles
    • DOI 10.1016/j.ijpharm.2005.05.028, PII S0378517305003406
    • Y.K. Katare, T. Muthukumaran, and A.K. Panda Influence of particle size, antigen load, dose and additional adjuvant on the immune response from antigen loaded PLA microparticles Int. J. Pharm. 301 2005 149 160 (Pubitemid 41206600)
    • (2005) International Journal of Pharmaceutics , vol.301 , Issue.1-2 , pp. 149-160
    • Katare, Y.K.1    Muthukumaran, T.2    Panda, A.K.3
  • 25
    • 33646766149 scopus 로고    scopus 로고
    • Influences of excipients on in vitro release and in vivo performance of tetanus toxoid loaded polymer particles
    • DOI 10.1016/j.ejps.2006.01.010, PII S0928098706000273
    • Y.K. Katare, and A.K. Panda Influences of excipients on in vitro release and in vivo performances of tetanus toxoid loaded polymer particles Eur. J. Pharm. Sci. 28 2006 179 188 (Pubitemid 43766098)
    • (2006) European Journal of Pharmaceutical Sciences , vol.28 , Issue.3 , pp. 179-188
    • Katare, Y.K.1    Panda, A.K.2
  • 27
    • 78649574793 scopus 로고    scopus 로고
    • Macrophage and dendritic cell phenotypic diversity in the context of biomaterials
    • P.M. Kou, and J.E. Babensee Macrophage and dendritic cell phenotypic diversity in the context of biomaterials J. Biomed. Mater. Res. Part A 96A 2011 239 260
    • (2011) J. Biomed. Mater. Res. Part A , vol.96 A , pp. 239-260
    • Kou, P.M.1    Babensee, J.E.2
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 30
    • 0033012030 scopus 로고    scopus 로고
    • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
    • DOI 10.1016/S0022-1759(98)00204-X, PII S002217599800204X
    • M.B. Lutz, N. Kukutsch, A.L. Ogilvie, S. Rössner, F. Koch, N. Romani, and G. Schuler An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow J. Immunol. Methods 223 1999 77 92 (Pubitemid 29096240)
    • (1999) Journal of Immunological Methods , vol.223 , Issue.1 , pp. 77-92
    • Lutz, M.B.1    Kukutsch, N.2    Ogilvie, A.L.J.3    Rossner, S.4    Koch, F.5    Romani, N.6    Schuler, G.7
  • 31
    • 79551528343 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of WGA-carbopol modified liposomes as carriers for oral peptide delivery
    • A. Makhlof, S. Fujimoto, Y. Tozuka, and H. Takeuchi In vitro and in vivo evaluation of WGA-carbopol modified liposomes as carriers for oral peptide delivery Eur. J. Pharm. Biopharm. 77 2011 216 224
    • (2011) Eur. J. Pharm. Biopharm. , vol.77 , pp. 216-224
    • Makhlof, A.1    Fujimoto, S.2    Tozuka, Y.3    Takeuchi, H.4
  • 32
    • 80052030876 scopus 로고    scopus 로고
    • Enhancing immunogenicity to PLGA microparticulate systems by incorporation of alginate and RGD-modified alginate
    • E. Mata, M. Igartua, M.E. Patarroyo, J.L. Pedraz, and R.M. Hernández Enhancing immunogenicity to PLGA microparticulate systems by incorporation of alginate and RGD-modified alginate Eur. J. Pharm. Sci. 44 2011 32 40
    • (2011) Eur. J. Pharm. Sci. , vol.44 , pp. 32-40
    • Mata, E.1    Igartua, M.2    Patarroyo, M.E.3    Pedraz, J.L.4    Hernández, R.M.5
  • 33
    • 0035800757 scopus 로고    scopus 로고
    • A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR: Subunit organization and binding to multivalent ligands
    • D.A. Mitchell, A.J. Fadden, and K. Drickamer A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR: Subunit organization and binding to multivalent ligands J. Biol. Chem. 276 2001 28939 28945
    • (2001) J. Biol. Chem. , vol.276 , pp. 28939-28945
    • Mitchell, D.A.1    Fadden, A.J.2    Drickamer, K.3
  • 34
    • 0037654710 scopus 로고    scopus 로고
    • Microparticles as vaccine adjuvants and delivery systems
    • DOI 10.1586/14760584.2.2.269
    • D. O'Hagan, and M. Singh Microparticles as vaccine delivery and adjuvant system Expert Rev. Vaccines 2 2003 269 283 (Pubitemid 36559931)
    • (2003) Expert Review of Vaccines , vol.2 , Issue.2 , pp. 269-283
    • O'Hogan, D.T.1    Singh, M.2
  • 35
    • 77956494575 scopus 로고    scopus 로고
    • Nano-microparticles as immune adjuvanyts: Corelating particle sizes and the resultant imune reponses
    • M.O. Oyewumi, A. Kumar, and Z. Cui Nano-microparticles as immune adjuvanyts: corelating particle sizes and the resultant imune reponses Expert Rev. Vaccines 9 2010 1059 1107
    • (2010) Expert Rev. Vaccines , vol.9 , pp. 1059-1107
    • Oyewumi, M.O.1    Kumar, A.2    Cui, Z.3
  • 37
    • 33745988599 scopus 로고    scopus 로고
    • Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins
    • DOI 10.1074/jbc.M601925200
    • A.S. Powlesland, E.M. Ward, S.K. Sadhu, Y. Guo, M.E. Taylor, and K. Drickamer Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins J. Biol. Chem. 281 2006 20440 20449 (Pubitemid 44065817)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.29 , pp. 20440-20449
    • Powlesland, A.S.1    Ward, E.M.2    Sadhu, S.K.3    Guo, Y.4    Taylor, M.E.5    Drickamer, K.6
  • 38
    • 0036805063 scopus 로고    scopus 로고
    • Improved immune response from biodegradable polymer particles entrapping tetanus toxoid by use of different immunization protocol and adjuvants
    • DOI 10.1016/S0378-5173(02)00342-3, PII S0378517302003423
    • R.S. Raghuvanshi, Y. Katare, K. Lalwani, M.M. Ali, Om. Singh, and A.K. Panda Improved immune response from biodegradable polymer particles entrapping tetanus toxoid by use of different immunization protocol and adjuvants Int. J. Pharm. 245 2002 109 121 (Pubitemid 35299897)
    • (2002) International Journal of Pharmaceutics , vol.245 , Issue.1-2 , pp. 109-121
    • Raghuvanshi, R.S.1    Katare, Y.K.2    Lalwani, K.3    Ali, M.M.4    Singh, O.5    Panda, A.K.6
  • 40
    • 0037130209 scopus 로고    scopus 로고
    • Residual polyvinyl alcohol associated with poly (D,L-lactide-co- glycolide) nanoparticles affects their physical properties and cellular uptake
    • DOI 10.1016/S0168-3659(02)00127-X, PII S016836590200127X
    • S.K. Sahoo, J. Panyam, S. Prabha, and V. Labhasetwar Residual polyvinyl alcohol associated with poly (D, L-lactide-co-glycolide) nanoparticles affects their physical properties and cellular uptake J. Control. Release 82 2002 105 114 (Pubitemid 34775052)
    • (2002) Journal of Controlled Release , vol.82 , Issue.1 , pp. 105-114
    • Sahoo, S.K.1    Panyam, J.2    Prabha, S.3    Labhasetwar, V.4
  • 43
    • 79551477301 scopus 로고    scopus 로고
    • Tumour- associated glycan modifications of antigen enhance MGL2 dependent uptake and MHC class i restricted CD8 T cell responses
    • S.K. Singh, I. Streng-Ouwehand, M. Litjens, H. Kalay, E. Saeland, and Y. van Kooyk Tumour- associated glycan modifications of antigen enhance MGL2 dependent uptake and MHC class I restricted CD8 T cell responses Int. J. Cancer 128 2011 1371 1383
    • (2011) Int. J. Cancer , vol.128 , pp. 1371-1383
    • Singh, S.K.1    Streng-Ouwehand, I.2    Litjens, M.3    Kalay, H.4    Saeland, E.5    Van Kooyk, Y.6
  • 44
    • 21244473965 scopus 로고    scopus 로고
    • Unfolding studies on soybean agglutinin and Concanavalin A tetramers: A comparative account
    • DOI 10.1529/biophysj.104.051052
    • S. Sinha, N. Mitra, G. Kumar, K. Bajaj, and A. Surolia Unfolding studies on soybean agglutinin and concanavalin a tetramers: a comparative account Biophys. J. 88 2005 1300 1310 (Pubitemid 40975957)
    • (2005) Biophysical Journal , vol.88 , Issue.2 , pp. 1300-1310
    • Sinha, S.1    Mitra, N.2    Kumar, G.3    Bajaj, K.4    Surolia, A.5
  • 45
    • 33846005807 scopus 로고    scopus 로고
    • Attributes of glycosylation in the establishment of the unfolding pathway of soybean agglutinin
    • DOI 10.1529/biophysj.106.092668
    • S. Sinha, and A. Surolia Attributes of glycosylation in the establishment of the unfolding pathway of soybean agglutinin Biophys. J. 92 2007 208 216 (Pubitemid 46048429)
    • (2007) Biophysical Journal , vol.92 , Issue.1 , pp. 208-216
    • Sinha, S.1    Surolia, A.2
  • 46
    • 70350005164 scopus 로고    scopus 로고
    • Toll-like receptor 2 and DC-SIGNR1 differentially regulate suppressors of cytokine signaling 1 in dendritic cells during Mycobacterium tuberculosis infection
    • V. Srivastava, M. Manchanda, S. Gupta, R. Singla, D. Behera, G. Das, and K. Natarajan Toll-like receptor 2 and DC-SIGNR1 differentially regulate suppressors of cytokine signaling 1 in dendritic cells during Mycobacterium tuberculosis infection J. Biol. Chem. 284 2009 25532 25541
    • (2009) J. Biol. Chem. , vol.284 , pp. 25532-25541
    • Srivastava, V.1    Manchanda, M.2    Gupta, S.3    Singla, R.4    Behera, D.5    Das, G.6    Natarajan, K.7
  • 47
    • 77954534278 scopus 로고    scopus 로고
    • C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecules that guides dendritic cells in immunity
    • U. Svajger, M. Anderluh, M. Jeras, and N. Obermajer C-type lectin DC-SIGN: an adhesion, signalling and antigen-uptake molecules that guides dendritic cells in immunity Cellular Signall. 22 2010 1397 1405
    • (2010) Cellular Signall. , vol.22 , pp. 1397-1405
    • Svajger, U.1    Anderluh, M.2    Jeras, M.3    Obermajer, N.4
  • 48
    • 0024644046 scopus 로고
    • Studies on the tryptophan residues of soybean agglutinin. Involvement in saccharide binding
    • M.J. Swamy, and A. Surolia Studies on the tryptophan residues of soybean agglutinin. Involvement in saccharide binding Biosci. Rep. 9 1989 189 198
    • (1989) Biosci. Rep. , vol.9 , pp. 189-198
    • Swamy, M.J.1    Surolia, A.2
  • 49
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • O. Takeuchi, and S. Akira Pattern recognition receptors and inflammation Cell 140 2010 805 820
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 50
    • 77952774795 scopus 로고    scopus 로고
    • Human plasmacytoid dendritic cells phagocytose, process, and present exogenous particulate antigen
    • J. Tel, A.J. Lambeck, L.J. Cruz, P.J. Tacken, I.J. de Vries, and C.G. Figdor Human plasmacytoid dendritic cells phagocytose, process, and present exogenous particulate antigen J. Immunol. 184 2010 4276 4283
    • (2010) J. Immunol. , vol.184 , pp. 4276-4283
    • Tel, J.1    Lambeck, A.J.2    Cruz, L.J.3    Tacken, P.J.4    De Vries, I.J.5    Figdor, C.G.6
  • 51
    • 79951683467 scopus 로고    scopus 로고
    • 'Dressed for success' C-type lectin receptors for the delivery of glyco-vaccines to dendritic cells
    • W.W. Unger, and Y. van Kooyk 'Dressed for success' C-type lectin receptors for the delivery of glyco-vaccines to dendritic cells Curr. Opin. Immunol. 23 2011 131 137
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 131-137
    • Unger, W.W.1    Van Kooyk, Y.2
  • 52
    • 67649920882 scopus 로고    scopus 로고
    • Modulation of innate and adaptive immunity by biodegradable nanoparticles
    • T. Uto, T. Akagi, T. Hamsaki, M. Akashi, and M. Baba Modulation of innate and adaptive immunity by biodegradable nanoparticles Immunol. Lett. 125 2009 46 52
    • (2009) Immunol. Lett. , vol.125 , pp. 46-52
    • Uto, T.1    Akagi, T.2    Hamsaki, T.3    Akashi, M.4    Baba, M.5
  • 54
    • 9244241499 scopus 로고    scopus 로고
    • PLGA microspheres for improved antigen delivery to dendritic cells as cellular vaccines
    • DOI 10.1016/j.addr.2004.09.007, PII S0169409X04002145
    • Y. Waeckerle-Men, and M. Groettrup PLGA microspheres for improved antigen delivery to dendritic cells as cellular vaccines Adv. Drug Deliv. Rev. 57 2005 475 482 (Pubitemid 39550972)
    • (2005) Advanced Drug Delivery Reviews , vol.57 , Issue.SPEC. ISS. 3 , pp. 475-482
    • Waeckerle-Men, Y.1    Groettrup, M.2
  • 56
    • 55549139082 scopus 로고    scopus 로고
    • Mannose-based molecular patterns on stealth microspheres for receptor-specific targeting of human antigen-presenting cells
    • U. Wattendorf, G. Coullerez, J. Vörös, M. Textor, and H.P. Merkle Mannose-based molecular patterns on stealth microspheres for receptor-specific targeting of human antigen-presenting cells Langmuir 24 2008 11790 11802
    • (2008) Langmuir , vol.24 , pp. 11790-11802
    • Wattendorf, U.1    Coullerez, G.2    Vörös, J.3    Textor, M.4    Merkle, H.P.5
  • 58
    • 40949126875 scopus 로고    scopus 로고
    • The effect of poly(D, L-lactide-co-glycolide) microparticles with polyelectrolyte self-assembled multilayer surfaces on the cross-presentation of exogenous antigens
    • Y.W. Yang, and P.Y. Hsu The effect of poly(D, L-lactide-co-glycolide) microparticles with polyelectrolyte self-assembled multilayer surfaces on the cross-presentation of exogenous antigens Biomaterials 29 2008 2516 2526
    • (2008) Biomaterials , vol.29 , pp. 2516-2526
    • Yang, Y.W.1    Hsu, P.Y.2
  • 59
    • 34548828056 scopus 로고    scopus 로고
    • Preparation and evaluation of lectin-conjugated PLGA nanoparticles for oral delivery of thymopentin
    • DOI 10.1016/j.jconrel.2006.09.015, PII S0168365906004810
    • Y. Yin, D. Chen, M. Qiao, Z. Lu, and H. Hu Preparation and evaluation of lectin-conjugated PLGA nanoparticles for oral delivery of thymopentin J. Control. Release 116 2006 337 345 (Pubitemid 44827411)
    • (2006) Journal of Controlled Release , vol.116 , Issue.3 , pp. 337-345
    • Yin, Y.1    Chen, D.2    Qiao, M.3    Lu, Z.4    Hu, H.5


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