Photochemical internalisation of a macromolecular protein toxin using a cell penetrating peptide-photosensitiser conjugate

Journal of Controlled Release

Volumn 157, Issue 2, 2012, Pages 305-313

  Wang, Julie T W ^a   Giuntini, Francesca ^b   Eggleston, Ian M ^b   Bown, Stephen G ^a   MacRobert, Alexander J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b University of Bath   (United Kingdom)

Author keywords

Cell penetrating peptide; PCI; PDT; Photochemical internalisation; Photodynamic therapy; Tat peptide

Indexed keywords

CELL-PENETRATING PEPTIDE; PCI; PDT; PHOTOCHEMICAL INTERNALISATION; TAT PEPTIDE;

BIOMOLECULES; CELL CULTURE; DISEASES; FLUORESCENCE; HYDROPHOBICITY; INTERFACES (COMPUTER); MACROMOLECULES; PEPTIDES; PHOTODYNAMIC THERAPY; PORPHYRINS;

CELLS;

AMPHOPHILE; SAPORIN; SINGLET OXYGEN; TETRAPHENYLPORPHYRIN DERIVATIVE; TRANSACTIVATOR PROTEIN; WATER;

ABSORPTION SPECTROSCOPY; AMINO ACID SEQUENCE; ARTICLE; CANCER CELL CULTURE; CELL TRANSPORT; CELL VIABILITY; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONJUGATE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; ENDOSOME; FLUORESCENCE IMAGING; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; INTERMETHOD COMPARISON; LYSOSOME; MACROMOLECULE; PHOTOBIOLOGY; PHOTOCHEMICAL INTERNALIZATION; PHOTOTOXICITY; PRIORITY JOURNAL; PROTEIN TRANSPORT; QUANTUM YIELD; SOLUBILITY; SQUAMOUS CELL CARCINOMA;

CELL LINE, TUMOR; CELL SURVIVAL; CELL-PENETRATING PEPTIDES; HUMANS; LIGHT; NEOPLASMS; PEPTIDE FRAGMENTS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84855782572     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.08.025     Document Type: Article

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