Genetic variation in GOLM1 and prefrontal cortical volume in Alzheimer's disease

Neurobiology of Aging

Volumn 33, Issue 3, 2012, Pages 457-465

  Inkster, Becky ^a,b   Rao, Anil W ^a   Ridler, Khanum ^a   Filippini, Nicola ^c,d,e   Whitcher, Brandon ^a   Nichols, Thomas E ^a,c   Wetten, Sally ^a   Gibson, Rachel A ^f   Borrie, Michael ^g   Kertesz, Andrew ^g   Guzman, Danilo A ^h   Loy English, Inge ^h   Williams, Julie ⁱ   Saemann, Philipp G ^j   Auer, Dorothee P ^j   Holsboer, Florian ^j   Tozzi, Federica ^k   Muglia, Pierandrea ^k   Merlo Pich, Emilio ^k   Matthews, Paul M ^a,b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f GLAXOSMITHKLINE   (United Kingdom)

^g UNIVERSITY OF WESTERN ONTARIO   (Canada)

^h UNIVERSITY OF OTTAWA   (Canada)

ⁱ CARDIFF UNIVERSITY   (United Kingdom)

^j MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^k GSK   (Italy)

more..

Author keywords

Alzheimer's disease; Genetic association; GOLM1; Prefrontal cortex; Voxel based morphometry

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN SIZE; CONTROLLED STUDY; FEMALE; FRONTAL GYRUS; GENE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GOLM1 GENE; GRAY MATTER; HUMAN; MAJOR CLINICAL STUDY; MALE; PREFRONTAL CORTEX; PRIORITY JOURNAL; VOXEL BASED MORPHOMETRY;

ADULT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ATROPHY; FEMALE; GENETIC VARIATION; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; PREFRONTAL CORTEX; YOUNG ADULT;

EID: 84855769335     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.04.018     Document Type: Article

References (43)

1. Allen Brain Atlas. http://www.brain-map.org.
2. Diagnostic and Statistical Manual of Mental Disorders 1994, American Psychiatric Association, American Psychiatric Association, Washington, DC. fourth ed.
3. Antúnez C., Boada M., López-Arrieta J., Ramirez-Lorca R., Hernández I., Marín J., Martínez-Lage P., González-Pérez A., Jorge Galan J., Gayán J., Real L.M., Ruiz A. GOLPH2 gene markers are not associated with Alzheimer's disease in a sample of the Spanish population. J. Alzheimers Dis. 2009, 18:751-754.
4. Bachert C., Fimmel C., Linstedt A.D. Endosomal trafficking and proprotein convertase cleavage of cis Golgi protein GP73 produces marker for hepatocellular carcinoma. Traffic 2007, 8:1415-1423.
5. Badre D., Wagner A.D. Left ventrolateral prefrontal cortex and the cognitive control of memory. Neuropsychologia 2007, 45:2883-2901.
6. Barnes J., Bartlett J.W., van de Pol L.A., Loy C.T., Scahill R.I., Frost C., Thompson P., Fox N.C. A meta-analysis of hippocampal atrophy rates in Alzheimer's disease. Neurobiol. Aging 2009, 30:1711-1723.
7. Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
8. Blacker D., Bertram L., Saunders A.J., Moscarillo T.J., Albert M.S., Wiener H., Perry R.T., Collins J.S., Harrell L.E., Go R.C., Mahoney A., Beaty T., Fallin M.D., Avramopoulos D., Chase G.A., Folstein M.F., McInnis M.G., Bassett S.S., Doheny K.J., Pugh E.W., Tanzi R.E. Results of a high-resolution genome screen of 437 Alzheimer's disease families. Hum. Mol. Genet. 2003, 12:23-32. NIMH Genetics Initiative Alzheimer's Disease Study Group.
9. Boccardi M., Sabattoli F., Testa C., Beltramello A., Soininen H., Frisoni G.B. APOE and modulation of Alzheimer's and frontotemporal dementia. Neurosci. Lett. 2004, 356:167-170.
10. Chan D., Janssen J.C., Whitwell J.L., Watt H.C., Jenkins R., Frost C., Rossor M.N., Fox N.C. Change in rates of cerebral atrophy over time in early-onset Alzheimer's disease: longitudinal MRI study. Lancet 2003, 362:1121-1122.
11. Curtis D., North B.V., Sham P.C. A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. Ann. Hum. Genet. 2001, 65(Pt 5):473-481.
12. Filippini N., Rao A., Wetten S., Gibson R.A., Borrie M., Guzman D., Kertesz A., Loy-English I., Williams J., Nichols T., Whitcher B., Matthews P.M. Anatomically-distinct genetic associations of Apoe e4 allele load with regional cortical atrophy in Alzheimer's disease. Neuroimage 2009, 44:724-728.
13. Folstein M.F., Folstein S.E., McHugh P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 1975, 12:189-198.
14. Geroldi C., Pihlajamaki M., Laakso M.P., deCarli C., Beltramello A., Bianchetti A., Soininen H., Trabucchi M., Frisoni G.B. APOE-epsilon4 is associated with less frontal and more medial temporal lobe atrophy in AD. Neurology 1999, 53:1825-1832.
15. Good C.D., Johnsrude I.S., Ashburner J., Henson R.N., Friston K.J., Frackowiak R.S. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001, 14:21-36.
16. Hashimoto M., Yasuda M., Tanimukai S., Matsui M., Hirono N., Kazui H., Mori E. Apolipoprotein E epsilon 4 and the pattern of regional brain atrophy in Alzheimer's disease. Neurology 2001, 57:1461-1466.
17. Hayasaka S., Phan K.L., Liberzon I., Worsley K.J., Nichols T.E. Nonstationary cluster- size inference with random field and permutation methods. Neuroimage 2004, 22:676-687.
18. Holmans P., Hamshere M., Hollingworth P., Rice F., Tunstall N., Jones S., Moore P., Wavrant DeVrieze F., Myers A., Crooks R., Compton D., Marshall H., Meyer D., Shears S., Booth J., Ramic D., Williams N., Norton N., Abraham R., Kehoe P., Williams H., Rudrasingham V., O'Donovan M., Jones L., Hardy J., Goate A., Lovestaone S., Owen M., Williams J. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2005, 135B:24-32.
19. Hu Z., Zeng L., Huang Z., Zhang J., Li T. The study of golgi apparatus in alzheimer's disease. Neurochem. Res. 2007, 32:1265-1277.
20. Inkster B., Nichols T.E., Saemann P.G., Auer D.P., Holsboer F., Muglia P., Matthews P.M. Association of GSK3beta polymorphisms with brain structural changes in major depressive disorder. Arch. Gen. Psychiatry 2009, 66:721-728.
21. Ioannidis J.P., Trikalinos T.A., Khoury M.J. Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am. J. Epidemiol. 2006, 164:609-614.
22. Jack C.R., Petersen R.C., Xu Y., O'Brien P.C., Smith G.E., Ivnik R.J., Boeve B.F., Tangalos E.G., Kokmen E. Rates of hippocampal atrophy correlate with change in clinical status in aging and AD. Neurology 2000, 55:484-489.
23. Judas M., Cepanec M. Adult structure and development of the human fronto-opercular cerebral cortex (Broca's region). Clin. Linguist. Phon. 2007, 21:975-989.
24. Kladney R.D., Bulla G.A., Guo L., Mason A.L., Tollefson A.E., Simon D.J., Koutoubi Z., Fimmel C.J. GP73, a novel Golgi-localized protein upregulated by viral infection. Gene 2000, 249:53-65.
25. Lee J.H., Cheng R., Santana V., Williamson J., Lantigua R., Medrano M., Arriaga A., Stern Y., Tycko B., Rogaeva E., Wakutani Y., Kawarai T., St George-Hyslop P., Mayeux R. Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease. Arch. Neurol. 2006, 63:1591-1598.
26. Lehtovirta M., Laakso M.P., Soininen H., Helisalmi S., Mannermaa A., Helkala E.L., Partanen K., Ryynanen M., Vainio P., Hartikainen P., et al. Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes. Neuroscience 1995, 67:65-72.
27. Lehtovirta M., Soininen H., Laakso M.P., Partanen K., Helisalmi S., Mannermaa A., Ryynanen M., Kuikka J., Hartikainen P., Riekkinen P.J. SPECT and MRI analysis in Alzheimer's disease: relation to apolipoprotein E epsilon 4 allele. J. Neurol. Neurosurg. Psychiatry 1996, 60:644-649.
28. Li H., Wetten S., Li L., St.Jean P.L., Upmanyu R., Surh L., Hosford D., Barnes M.R., Briley J.D., Borrie M., Coletta N., Delisle R., Dhalla D., Ehm M.G., Feldman H.H., Fornazzari L., Gauthier S., Goodgame N., Guzman D., Hammond S., Hollingworth P., Hsiung G.Y., Johnson J., Kelly D.D., Keren R., Kertesz A., King K.S., Lovestone S., Loy-English I., Matthews P.M., Owen M.J., Plumpton M., Pryse-Phillips W., Prinjha R.K., Richardson J.C., Saunders A., Slater A.J., St.George-Hyslop P.H., Stinnett S.W., Swartz J.E., Taylor R.L., Wherrett J., Williams J., Yarnall D.P., Gibson R.A., Irizarry M.C., Middleton L.T., Roses A.D. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch. Neurol. 2008, 65:45-53.
29. McDonalds C.R., McEvoy L.K., Gharapetian L., Fennema-Notestine C., Hagler D.J., Holland D., Koyama A., Brewer J.B., Dale A.M. Regional rates of neocortical atrophy from normal aging to Alzheimer's disease. Neurology 2009, 73:457-465. Alzheimer's Disease Neuroimaging Initiative.
30. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
31. Mudge J., Miller N.A., Khrebtukova I., Lindquist I.E., May G.D., Huntley J.J., Luo S., Zhang L., van Velkinburgh J.C., Farmer A.D., Lewis S., Beavis W.D., Schilkey F.D., Virk S.M., Black C.F., Myers M.K., Mader L.C., Langley R.J., Utsey J.P., Kim R.W., Roberts R.C., Khalsa S.K., Garcia M., Ambriz-Griffith V., Harlan R., Czika W., Martin S., Wolfinger R.D., Perrone-Bizzozero N.I., Schroth G.P., Kingsmore S.F. Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum. PLoS One 2008, 3:e3625.
32. Muglia P., Tozzi F., Galwey N.W., Francks C., Upmanyu R., Kong X.Q., Antoniades A., Domenici E., Perry J., Rothen S., Vandeleur C.L., Mooser V., Waeber G., Vollenweider P., Preisig M., Lucae S., Müller-Myhsok B., Holsboer F., Middleton L.T., Roses A.D. Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts. Mol. Psychiatry 2008, in press. PMID: 19107115.
33. Myers A., Wavrant De-Vrieze F., Holmans P., Hamshere M., Crook R., Compton D., Marshall H., Meyer D., Shears S., Booth J., Ramic D., Knowles H., Morris J.C., Williams N., Norton N., Abraham R., Kehoe P., Williams H., Rudrasingham V., Rice F., Giles P., Tunstall N., Jones L., Lovestone S., Williams J., Owen M.J., Hardy J., Goate A. Full genome screen for Alzheimer disease: stage II analysis. Am. J. Med. Genet. 2002, 114:235-244.
34. Nichols T., Hayasaka S. Controlling the familywise error rate in functional neuroimaging: a comparative review. Stat. Methods Med. Res. 2003, 12:419-446.
35. Olson J.M., Goddard K.A., Dudek D.M. A second locus for very-late-onset Alzheimer disease: a genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am. J. Hum. Genet. 2002, 71:154-161.
36. Pericak-Vance M.A., Grubber J., Bailey L.R., Hedges D., West S., Santoro L., Kemmerer B., Hall J.L., Saunders A.M., Roses A.D., Small G.W., Scott W.K., Conneally P.M., Vance J.M., Haines J.L. Identification of novel genes in late-onset Alzheimer's disease. Exp. Gerontol. 2000, 35:1343-1352.
37. Puri S., Bachert C., Fimmel C.J., Linstedt A.D. Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption. Traffic 2002, 3:641-653.
38. Schjeide B.M., Hooli B., Parkinson M., Hogan M.F., DiVito J., Mullin K., Blacker D., Tanzi R.E., Bertram L. GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. Arch. Neurol. 2009, 66:250-254.
39. Su A.I., Wiltshire T., Batalov S., Lapp H., Ching K.A., Block D., Zhang J., Soden R., Hayakawa M., Kreiman G., Cooke M.P., Walker J.R., Hogenesch J.B. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:6062-6067.
40. Tanaka S., Kawamata J., Shimohama S., Akaki H., Akiguchi I., Kimura J., Ueda K. Inferior temporal lobe atrophy and APOE genotypes in Alzheimer's disease. X-ray computed tomography, magnetic resonance imaging and Xe-133 SPECT studies. Dement. Geriatr. Cogn. Disord. 1998, 9:90-98.
41. Thompson P.M., Hayashi K.M., Dutton R.A., Chiang M.C., Leow A.D., Sowell E.R., De Zubicaray G., Becker J.T., Lopez O.L., Aizenstein H.J., Toga A.W. Tracking Alzheimer's disease. Ann. N.Y. Acad. Sci. 2007, 1097:183-214.
42. Tozzi F., Prokopenko I., Perry J.D., Kennedy J.L., McCarthy A.D., Holsboer F., Berrettini W., Middleton L.T., Chilcoat H.D., Muglia P. Family history of depression is associated with younger age of onset in patients with recurrent depression. Psychol. Med. 2008, 38:641-649.
43. Tzourio-Mazoyer N., Landbeau B., Papathanassiou D., Crivello F., Etard O., Delcroix N., Mazoyer B., Joliot M. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 2002, 15:273-289.