메뉴 건너뛰기




Volumn 111, Issue 11, 2011, Pages 2681-2686

EVect of N-acetyl-cysteine and hyperoxia on erythropoietin production

Author keywords

Endogenous erythropoietin; Hypoxia inducible factor; N acetyl cysteine; Normobaric oxygen

Indexed keywords

ACETYLCYSTEINE; ERYTHROPOIETIN; OXYGEN;

EID: 84855712426     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-011-1893-4     Document Type: Article
Times cited : (17)

References (29)
  • 1
    • 77449128363 scopus 로고    scopus 로고
    • Effects of glu-tathione depletion on hypoxia-induced erythropoietin production in rats
    • Ando D, Yamakita M, Yamagata Z, Koyama K (2009) Effects of glu-tathione depletion on hypoxia-induced erythropoietin production in rats. J Physiol Anthropol 28:211-215
    • (2009) J Physiol Anthropol , vol.28 , pp. 211-215
    • Ando, D.1    Yamakita, M.2    Yamagata, Z.3    Koyama, K.4
  • 2
    • 33646349265 scopus 로고    scopus 로고
    • Serum erythropoietin levels in healthy humans after a short period of normobaric and hyperbaric oxygen breathing: The "normobaric oxygen paradox"
    • DOI 10.1152/japplphysiol.00964.2005
    • Balestra C, Germonpré P, Poortmans JR, Marroni A (2006) Serum erythropoietin levels in healthy humans after a short period of normobaric and hyperbaric oxygen breathing: the "normobaric oxygen paradox". J Appl Physiol 100:512-518 (Pubitemid 43671602)
    • (2006) Journal of Applied Physiology , vol.100 , Issue.2 , pp. 512-518
    • Balestra, C.1    Germonpre, P.2    Poortmans, J.R.3    Marroni, A.4
  • 3
    • 35448979980 scopus 로고    scopus 로고
    • Oxygen breathing may be a cheaper and safer alternative to exogenous erythropoietin (EPO)
    • DOI 10.1016/j.mehy.2007.03.015, PII S0306987707002484
    • Burk R (2007) Oxygen breathing may be a cheaper and safer alternative to exogenous erythropoietin (EPO). Med Hypotheses 69:1200-1204 (Pubitemid 47633055)
    • (2007) Medical Hypotheses , vol.69 , Issue.6 , pp. 1200-1204
    • Burk, R.1
  • 5
    • 0033568576 scopus 로고    scopus 로고
    • Regulation of the erythropoietin gene
    • Ebert BL, Bunn HF (1999) Regulation of the erythropoietin gene. Blood 94:1864-1877 (Pubitemid 29430402)
    • (1999) Blood , vol.94 , Issue.6 , pp. 1864-1877
    • Ebert, B.L.1    Bunn, H.F.2
  • 6
    • 0021270306 scopus 로고
    • Effects of oxygen inhalation on endogenous erythropoietin kinetics, erythropoiesis, and properties of blood cells in sickle-cell anemia
    • Embury SH, Garcia JF, Mohandas N, Pennathur-Das R, Clark M (1984) Effects of oxygen inhalation on endogenous erythropoietin kinetics, erythropoiesis, and properties of blood cells in sickle-cell anemia. N Engl J Med 311:291-295 (Pubitemid 14091207)
    • (1984) New England Journal of Medicine , vol.311 , Issue.5 , pp. 291-295
    • Embury, S.H.1    Garcia, J.F.2    Mohandas, N.3
  • 7
    • 0036205024 scopus 로고    scopus 로고
    • Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans
    • DOI 10.1046/j.1365-201x.2002.00946.x
    • Freudenthaler SM, Schreeb KH, Wiese A, Pilz J, Gleiter CH (2002) Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans. Acta Physiol Scand 174:231-235 (Pubitemid 34264363)
    • (2002) Acta Physiologica Scandinavica , vol.174 , Issue.3 , pp. 231-235
    • Freudenthaler, S.M.1    Schreeb, K.-H.2    Wiese, A.3    Pilz, J.4    Gleiter, C.H.5
  • 9
    • 0347909240 scopus 로고    scopus 로고
    • Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and patho-physiology
    • Haddad JJ (2002) Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and patho-physiology. Respir Res 3:26
    • (2002) Respir Res , vol.3 , pp. 26
    • Haddad, J.J.1
  • 10
    • 0034102212 scopus 로고    scopus 로고
    • O2-evoked regulation of HIF-1α and NF-?B in perinatal lung epithelium requires glutathione biosynthesis
    • Haddad JJ, Land SC (2000) O2-evoked regulation of HIF-1α and NF-?B in perinatal lung epithelium requires glutathione biosynthesis. Am J Physiol Lung Cell Mol Physiol 278:492-503
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.278 , pp. 492-503
    • Haddad, J.J.1    Land, S.C.2
  • 11
    • 0034647933 scopus 로고    scopus 로고
    • Antioxidant/pro-oxidant equilibrium regulates HIF-1 and NF-kappaB redox sensitivity: Evidence for inhibition by glutathione oxidation in alveolar epithelial cells
    • DOI 10.1074/jbc.M000737200
    • Haddad JJ, Olver RE, Land SC (2000) Antioxidant/pro-oxidant equi-librium regulates HIF-1α and NF-?B redox sensitivity: evidence for inhibition by glutathione oxidation in alveolar epithelial cells. J Biol Chem 275:21130-21139 (Pubitemid 30481806)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.28 , pp. 21130-21139
    • Haddad, J.J.E.1    Olver, R.E.2    Land, S.C.3
  • 13
    • 0032493368 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1 alpha is mediated by an O2-dependent degrada-tion domain via the ubiquitin-proteasome pathway
    • Huang LE, Gu J, Schau M, Bunn HF (1998) Regulation of hypoxia-inducible factor 1 alpha is mediated by an O2-dependent degrada-tion domain via the ubiquitin-proteasome pathway. Proc Natl Acad Sci USA 95:7987-7992
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7987-7992
    • Huang, L.E.1    Gu, J.2    Schau, M.3    Bunn, H.F.4
  • 14
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1 by the ubiquitin-proteasome pathway
    • DOI 10.1074/jbc.274.10.6519
    • Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L (1999) Reg-ulation of the hypoxia-inducible transcription factor 1αby the ubiquitin-proteasome pathway. J Biol Chem 274:6519-6525 (Pubitemid 29111068)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.10 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 15
    • 79953690490 scopus 로고    scopus 로고
    • Acute normobaric hyperoxia tran-siently attenuates plasma EPO concentration in healthy males: Evidence against the "normobaric Oxygen Paradox" theory
    • doi: 10.1111/j.1748-1716.2011.02262.x
    • Keramidas ME, Kounalakis SN, Debevec T, Norman B, Gustafsson T, Eiken O, Mekjavic IB (2011) Acute normobaric hyperoxia tran-siently attenuates plasma EPO concentration in healthy males: evidence against the "Normobaric Oxygen Paradox" theory. Acta Physiol. doi: 10.1111/j.1748-1716.2011.02262.x
    • (2011) Acta Physiol.
    • Keramidas, M.E.1    Kounalakis, S.N.2    Debevec, T.3    Norman, B.4    Gustafsson, T.5    Eiken, O.6    Mekjavic, I.B.7
  • 16
    • 1342304166 scopus 로고    scopus 로고
    • Antioxidant intervention does not affect the response of plasma erythropoietin to short-term normobaric hypoxia in humans
    • DOI 10.1152/japplphysiol.00803.2003
    • Niess AM, Fehrenbach E, Lorenz I, Müller A, Northoff H, Dickhuth HH, Schneider EM (2004) Antioxidant intervention does not affect the response of plasma erythropoietin to short-term normo-baric hypoxia in humans. J Appl Physiol 96:1231-1235 (Pubitemid 38248706)
    • (2004) Journal of Applied Physiology , vol.96 , Issue.3 , pp. 1231-1235
    • Niess, A.M.1    Fehrenbach, E.2    Lorenz, I.3    Muller, A.4    Northoff, H.5    Dickhuth, H.-H.6    Schneider, E.M.7
  • 17
    • 75749150800 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-induc-ible factor stabilization
    • Paliege A, Rosenberger C, Bondke A, Sciesielski L, Shina A, Heyman SN, Flippin LA, Arend M, Klaus SJ, Bachman S (2010) Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-induc-ible factor stabilization. Kidney Int 77:312-318
    • (2010) Kidney Int , vol.77 , pp. 312-318
    • Paliege, A.1    Rosenberger, C.2    Bondke, A.3    Sciesielski, L.4    Shina, A.5    Heyman, S.N.6    Flippin, L.A.7    Arend, M.8    Klaus, S.J.9    Bachman, S.10
  • 19
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 (HIF-1) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • DOI 10.1074/jbc.272.36.22642
    • Salceda S, Caro J (1997) Hypoxia-inducible factor-1α (HIF1-α) pro-tein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions: its stabilization by hypoxia depends on redox-induced changes. J Biol Chem 272:22642-22647 (Pubitemid 27386079)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.36 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 21
    • 85047682984 scopus 로고    scopus 로고
    • Regulation of oxygen homeostasis by hypoxia-inducible factor-1
    • Semenza GL (2009) Regulation of oxygen homeostasis by hypoxia-inducible factor-1. Physiology 24:97-106
    • (2009) Physiology , vol.24 , pp. 97-106
    • Semenza, G.L.1
  • 22
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL, Wang GL (1992) A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12:5447-5454
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 23
    • 0017683950 scopus 로고
    • Analysis of prospective epidemiologic studies by minimum distance case control matching
    • Smith AH, Kark JD, Cassel JC, Spears GFS (1977) Analysis of pro-spective epidemiologic studies by minimum distance case-con-trol matching. Am J Epidemiol 105:567-574 (Pubitemid 8132173)
    • (1977) American Journal of Epidemiology , vol.105 , Issue.6 , pp. 567-574
    • Smith, A.H.1    Kark, J.D.2    Cassel, J.C.3    Spears, G.F.S.4
  • 24
    • 0034663894 scopus 로고    scopus 로고
    • Mechanism of regulation of the hypoxia-inducible factor-la by the von Hippel-Lindau tumor suppressor protein
    • Tanimoto K, Makino Y, Pereira T, Poellinger L (2000) Mechanism of regulation of the hypoxia-inducible factor-1α by the von Hippel-Lindau tumor suppressor protein. EMBO J 16:4298-4309 (Pubitemid 30623741)
    • (2000) EMBO Journal , vol.19 , Issue.16 , pp. 4298-4309
    • Tanimoto, K.1    Makino, Y.2    Pereira, T.3    Poellinger, L.4
  • 26
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang GL, Semenza GL (1995) Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270:1230-1237
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 28
    • 9444283176 scopus 로고    scopus 로고
    • Differentiating the functional role of hypoxia-inducible factor (HIF)-1 and HIF-2 (EPAS-1) by the use of RNA interference: Erythropoietin is a HIF-2 target gene in Hep3B and Kelly cells
    • DOI 10.1096/fj.04-1640fje
    • Warnecke C, Zaborowska Z, Kurreck J, Erdmann VA, Frei U, Wiesen-er M, Eckardt KU (2004) Differentiating the functional role of hypoxia-inducible factor (HIF)-1α and HIF-2α (Epas-1) by the use of RNA interference: erythropoietin is a HIF-2α target gene in Hep 3B and Kelly Cells. FASEB J 18:1462-1464 (Pubitemid 39561615)
    • (2004) FASEB Journal , vol.18 , Issue.12 , pp. 1462-1464
    • Warnecke, C.1    Zaborowska, Z.2    Kurreck, J.3    Erdmann, V.A.4    Frei, U.5    Wiesener, M.6    Eckardt, K.-U.7
  • 29
    • 77449148194 scopus 로고    scopus 로고
    • The comparison of antioxidant and haemato-logical properties of N-acetylcysteine and α-lipoic in physically active males
    • Zembron-Lacny A, Slowinska-Lisowska M, Szygula Z, Witkowski K, Szyszka K (2009) The comparison of antioxidant and haemato-logical properties of N-acetylcysteine and α-lipoic in physically active males. Physiol Res 58:855-861
    • (2009) Physiol Res , vol.58 , pp. 855-861
    • Zembron-Lacny, A.1    Slowinska-Lisowska, M.2    Szygula, Z.3    Witkowski, K.4    Szyszka, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.