Design, synthesis and evaluation of novel molecules with a diphenyl ether nucleus as potential antitubercular agents

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 954-957

  Yang, Yinghong ^a,b   Wang, Zhenling ^a   Yang, Jianzhong ^a   Yang, Tao ^a   Pi, Weiyi ^a   Ang, Wei ^b   Lin, Yanni ^a   Liu, Yuanyuan ^a   Li, Zicheng ^b   Luo, Youfu ^a   Wei, Yuquan ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Antituberculosis; BCG murine model; Diphenyl ether nucleus; H 37Rv

Indexed keywords

DIPHENYL ETHER DERIVATIVE; N (3,4 DICHLOROPHENYL) 2 (3 PHENOXYPHENYL)ACETAMIDE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SAFETY; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMINES; ANIMALS; ANTITUBERCULAR AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEP G2 CELLS; HUMANS; MICE; MICE, INBRED BALB C; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM TUBERCULOSIS; PHENYL ETHERS; STRUCTURE-ACTIVITY RELATIONSHIP;

MURINAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 84855702105     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.022     Document Type: Article

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