Identification of a potent and noncytotoxic inhibitor of melanin production

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 15, 2010, Pages 5602-5609

  Hwang, Soonho ^a   Choi, Sang Yoon ^b   Lee, Jin Hee ^c   Kim, Shinae ^a   In, Jinkyung ^a   Ha, Sang Keun ^b   Lee, Eunjung ^d   Kim, Tae Yoon ^d   Kim, Sun Yeou ^b   Choi, Sun ^c   Kim, Sanghee ^a  

^a Seoul National University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Ewha Womans University   (South Korea)

^d The Catholic University of Korea   (South Korea)

Author keywords

Biaryl amide library; Combinatorial chemistry; Depigmenting agents; Laplacian modified na ve Bayesian; Structure activity relationships

Indexed keywords

3 METHOXY N (4 METHOXYPHENYL)BENZAMIDE; 4 CYANO N (3,5 DIMETHYLPHENYL)BENZAMIDE; 4 CYANO N 3 TOLYLBENZAMIDE; AMIDE; DEPIGMENTING AGENT; MELANIN; METHYL 2 (4 METHOXYBENZAMIDO)BENZOATE; N (3 METHOXYPHENYL)FURAN 2 CARBOXAMIDE; N (3,5 DIMETHOXYPHENYL) 4 METHYLBENZAMIDE; N (3,5 DIMETHYLPHENYL) 3 METHOXYBENZAMIDE; N (3,5 DIMETHYLPHENYL) 4 ETHYLBENZAMIDE; N (3,5 DIMETHYLPHENYL) 4 METHYLBENZAMIDE; N (4 METHOXYPHENYL) 4 METHYLBENZAMIDE; PHENYLTHIOUREA; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; N-(3,5-DIMETHYLPHENYL)-3-METHOXYBENZAMIDE;

ANIMAL TISSUE; ARTICLE; CELL VIABILITY; COMPUTER MODEL; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; GUINEA PIG; IN VITRO STUDY; IN VIVO STUDY; MELANOGENESIS; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STRUCTURE ACTIVITY RELATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG EFFECTS; MELANOCYTE; METABOLISM; MOUSE; RADIATION RESPONSE; SKIN; SYNTHESIS; ULTRAVIOLET RADIATION;

AMIDES; ANIMALS; BENZAMIDES; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; GUINEA PIGS; MELANINS; MELANOCYTES; MICE; PHENYLTHIOUREA; SKIN; STRUCTURE-ACTIVITY RELATIONSHIP; ULTRAVIOLET RAYS;

EID: 77955421154     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.06.034     Document Type: Article

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