Amino and chlorambucil analogues of pentamidine - Synthesis and biological examinations

Acta Poloniae Pharmaceutica - Drug Research

Volumn 69, Issue 1, 2012, Pages 63-73

  Pućkowska, Anna ^a   Drozdowska, Danuta ^a   Rusak, Małgorzata ^a   Bielawski, Tomasz ^a   Bruzgo, Irena ^a   Midura Nowaczek, Krystyna ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Anticancer activity; Chlorambucil; DNA binding; Pentamidine; Topoisomerase

Indexed keywords

1,3 BIS[4 [4 [4 DI(2 CHLOROETHYL)AMINO]PHENYL]BUTANOYLAMINO 2 [(3 DIMETHYLAMINOPROPYL)CARBAMOYL]PHENYLOXY]PROPANE TETRAHYDROCHLORIDE; 1,3 BIS[4 AMINO 2 [(3 DIMETHYLAMINOPROPYL)CARBAMOYL]PHENYLOXY]PROPANE TETRAHYDROCHLORIDE; 1,4 BIS[4 [4 [4 DI(2 CHLOROETHYL)AMINO]PHENYL]BUTANOYLAMINO 2 [(3 DIMETHYLAMINOPROPYL)CARBAMOYL]PHENYLOXY]BUTANE TETRAHYDROCHLORIDE; 1,5 BIS[4 [4 [4 DI(2 CHLOROETHYL)AMINO]PHENYL]BUTANOYLAMINO 2 [(3 DIMETHYLAMINOPROPYL)PHENYLOXY]PENTANE TETRAHYDROCHLORIDE; 1,5 BIS[4 AMINO 2 [(3 DIMETHYLAMINOPROPYL)CARBAMOYL]PHENYLOXY]PENTANE TETRAHYDROCHLORIDE; 1,6 BIS[4 [4 [4 DI(2 CHLOROETHYL)AMINO]PHENYL]BUTANOYLAMINO 2 [(3 DIMETHYLAMINOPROPYL)PHENYLOXY]HEXANE TETRAHYDROCHLORIDE; AMINO ACID DERIVATIVE; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); PENTAMIDINE; PLASMID DNA; PLASMIN; TRYPSIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; COLIPHAGE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DNA BINDING; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANTIFIBRINOLYTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CHLORAMBUCIL; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PENTAMIDINE; STRUCTURE-ACTIVITY RELATIONSHIP; TOPOISOMERASE I INHIBITORS; TOPOISOMERASE II INHIBITORS; TRYPSIN INHIBITORS;

EID: 84855667023     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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