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Volumn 39, Issue 1, 2004, Pages 99-105
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Aromatic analogues of DNA minor groove binders - Synthesis and biological evaluation
a
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Author keywords
Bis netropsin; Cytotoxicity; DNA topoisomerase; Minor groove binding; Netropsin
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Indexed keywords
1,4 BIS[4 AMINO 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENYLOXY]BUTANE;
1,4 BIS[4 [(3 AMINO)BENZAMIDO] 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENYLOXY]BUTANE;
1,4 BIS[4 [(4 AMINO)BENZAMIDO] 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENYLOXY]BUTANE;
1,4 BIS[4 [(5 AMINO 2 METHOXY)BENZAMIDO] 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENYLOXY]BUTANE;
1,6 BIS[4 (3 AMINO)BENZAMIDO 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENYLOXY]HEXANE;
1,6 BIS[4 (4 AMINO)BENZAMIDO 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENYLOXY]HEXANE;
1,6 BIS[4 AMINO 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENYLOXY]HEXANE;
1,6 BIS[4 [(5 AMINO 2 METHOXY)BENZAMIDO] 2 [(1,5 DIAZA 5 METHYLHEXYL)CARBONYL]PHENOXY]BUTANE;
4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL;
DNA TOPOISOMERASE;
DNA TOPOISOMERASE (ATP HYDROLYSING);
ENZYME INHIBITOR;
N [4 (5 AMINO 2 METHOXYBENZAMIDO]BENZOYL N',N' DIMETHYLPROPYL 1,3 DIAMINE;
N [5 (3 AMINO)BENZAMIDO 2 METHOXY]BENZOYL N',N' DIMETHYLPROPYL 1,3 DIAMINE;
N [5 (4 AMINO)BENZAMIDO 2 METHOXY]BENZOYL N',N' DIMETHYLPROPYL 1,3 DIAMINE;
N [5 (5 AMINO 2 METHOXY)BENZAMIDO 2 METHOXY]BENZOYL N',N' DIMETHYLPROPYL 1,3 DIAMINE;
UNCLASSIFIED DRUG;
ARTICLE;
CELL STRAIN MCF 7;
CONTROLLED STUDY;
DNA DRUG COMPLEX;
DNA SYNTHESIS;
DRUG CYTOTOXICITY;
DRUG POTENCY;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
IC 50;
LIGAND BINDING;
PROTEINASE INHIBITION;
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EID: 1342343183
PISSN: 02235234
EISSN: None
Source Type: Journal
DOI: 10.1016/j.ejmech.2003.11.005 Document Type: Article |
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Times cited : (21)
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References (14)
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