Regulation of prostate cancer immunity-related genes in pc3 prostate cancer cells by ETS-1

Oncology Letters

Volumn 3, Issue 3, 2012, Pages 513-516

  Adler, David ^a   Lindstrot, Andreas ^a   Buettner, Reinhard ^a   Wernert, Nicolas ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

ETS 1; Transcriptional regulation

Indexed keywords

BCL11A PROTEIN; CRISP3 PROTEIN; DMBT1 PROTEIN; FGR PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; PROTEIN; SAA1 PROTEIN; TRANSCRIPTION FACTOR ETS 1; UNCLASSIFIED DRUG;

ANTISENSE VECTOR; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC REGULATION; IN VITRO STUDY; MICROARRAY ANALYSIS; PROSTATE CANCER; TUMOR CELL LINE;

EID: 84855666961     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2011.509     Document Type: Article

References (28)

1. Kumar-Sinha C, Tomlins SA and Chinnaiyan AM: Recurrent gene fusions in prostate cancer. Nature Rev 8: 497-511, 2008.
2. Hsu DS, Kim MK, Balakumaran BS, et al: Immune signatures predict prognosis in localized cancer. Cancer Invest 28: 765-773, 2010.
3. Lin WW and Karin M: A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117: 1175-1183, 2007.
4. Shimura S, Yang G, Ebara S, Wheeler TM, Frolov A and Thompson TC: Reduced infiltration of tumor-associated macrophages in human prostate cancer: association with cancer progression. Cancer Res 60: 5857-5861, 2000.
5. Vesalainen S, Lipponen P, Talja M and Syrjanen K: Histological grade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma. Eur J Cancer 30A: 1797-1803, 1994.
6. Rajarubendra N, Lawrentschuk N, Bolton DM, Klotz L and DavisID: Prostate cancer immunology an update for Urologists. BJU Int 107: 1046-1051, 2010.
7. Shaikhibrahim Z LA, Ellinger J, Rogenhofer S, Buettner R and Wernert N: Identification of immunity-related genes in prostate cancer and potential role of the ETS family of transcription factors in their regulation. Int J Mol Med 28: 799-807, 2011.
8. Tomlins SA, Rhodes DR, Perner S, et al: Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-648, 2005.
9. Gallant S and Gilkeson G: ETS transcription factors and regulation of immunity. Arch Immunol Ther Exp (Warsz) 54: 149-163, 2006.
10. Alipov G, Nakayama T, Ito M, et al: Overexpression of Ets-1 proto-oncogene in latent and clinical prostatic carcinomas. Histopathology 46: 202-208, 2005.
11. Rothhammer T, Hahne JC, Florin A, et al: The Ets-1 transcription factor is involved in the development and invasion of malignant melanoma. Cell Mol Life Sci 61: 118-128, 2004.
12. Hahne JC, Okuducu AF, Kaminski A, Florin A, Soncin F and Wernert N: Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage independent growth. Oncogene 24: 5384-5388, 2005.
13. Sahin A, Vercamer C, Kaminski A, et al: Dominant-negative inhibition of Ets 1 suppresses tumor growth, invasion and migration in rat C6 glioma cells and reveals differentially expressed Ets 1 target genes. Int J Oncol 34: 377-389, 2009.
14. Shaikhibrahim Z, Langer B, Lindstrot A, et al: Ets-1 is implicated in the regulation of androgen co-regulator FHL2 and reveals specificity for migration, but not invasion, of PC3 prostate cancer cells. Oncol Rep 25: 1125-1129, 2011.
15. Shaikhibrahim Z, Lindstrot A, Langer B, Buettner R and Wernert N: Comprehensive gene expression microarray analysis of Ets-1 blockade in PC3 prostate cancer cells and correlations with prostate cancer tissues: Insights into genes involved in the metastatic cascade. Int J Mol Med 27: 811-819, 2011.
16. Chen CA and Okayama H: Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. BioTechniques 6: 632-638, 1988.
17. Liu AY, Roudier MP and True LD: Heterogeneity in primary and metastatic prostate cancer as defined by cell surface CD profile. Am J Pathol 165: 1543-1556, 2004.
18. Milde T, Oehme I, Korshunov A, et al: HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clin Cancer Res 16: 3240-3252, 2010
19. Moreno DA, Scrideli CA, Cortez MA, et al: Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia. Br J Haematol 150: 665-673, 2010.
20. Satterwhite E, Sonoki T, Willis TG, et al: The BCL11 gene family: involvement of BCL11A in lymphoid malignancies. Blood 98: 3413-3420, 2001.
21. Kosari F, Asmann YW, Cheville JC and Vasmatzis G: Cysteine-rich secretory protein-3: a potential biomarker for prostate cancer. Cancer Epidemiol Biomarkers Prev 11: 1419-1426, 2002.
22. Bjartell AS, Al-Ahmadie H, Serio AM, et al: Association of cysteine-rich secretory protein 3 and beta-microseminoprotein with outcome after radical prostatectomy. Clin Cancer Res 13: 4130-4138, 2007.
23. Mollenhauer J, Wiemann S, Scheurlen W, et al: DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nat Genet 17: 32-39, 1997.
24. Mollenhauer J, Herbertz S, Holmskov U, et al: DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer. Cancer Res 60: 1704-1710, 2000.
25. Kim HS, Han HD, Armaiz-Pena GN, et al: Functional roles of Src and Fgr in ovarian carcinoma. Clin Cancer Res 17: 171-1721, 2011.
26. Yoo KH, Kim SK, Chung JH and Chang SG: Nitric oxide synthase 2 gene polymorphisms are associated with prostatic volume in Korean men with benign prostatic hyperplasia. Asian J Androl 12: 690-696, 2010.
27. Sung HJ, Ahn JM, Yoon YH, et al: Identification and validation of SAA as a potential lung cancer biomarker and its involvement in metastatic pathogenesis of lung cancer. J Proteome Res 10: 1383-1395, 2011.
28. Urieli-Shoval S, Finci-Yeheskel Z, Dishon S, et al: Expression of serum amyloid a in human ovarian epithelial tumors: implication for a role in ovarian tumorigenesis. J Histochem Cytochem 58: 1015-1023, 2010.