A comparison of the α2/3/5 selective positive allosteric modulators L-838,417 and TPA023 in preclinical models of inflammatory and neuropathic pain

Advances in Pharmacological Sciences

Volumn 2011, Issue , 2011, Pages

  Nickolls, Sarah ^a   MacE, Hannah ^a   Fish, Rebecca ^a   Edye, Michelle ^a   Gurrell, Rachel ^a   Ivarsson, Magnus ^a   Pitcher, Tom ^a   Tanimoto Mori, Sachi ^a   Richardson, Denise ^a   Sweatman, Catherine ^a   Nicholson, Janet ^a   Ward, Cameron ^a   Jinks, John ^a   Bell, Christine ^a   Young, Kimberly ^a   Rees, Huw ^a   Moss, Andrew ^a   Kinloch, Ross ^a   McMurray, Gordon ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA3; 4 AMINOBUTYRIC ACID A RECEPTOR ALPHA5; 7 TERT BUTYL 3 (2,5 DIFLUOROPHENYL) 6 (2 METHYL 2H 1,2,4 TRIAZOL 3 YLMETHOXY) 1,2,4 TRIAZOLO[4,3 B]PYRIDAZINE; ANALGESIC AGENT; BRETAZENIL; PREGABALIN; TPA 023; UNCLASSIFIED DRUG;

ALLODYNIA; ALLOSTERISM; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG EFFICACY; ELECTROPHYSIOLOGY; EVOKED RESPONSE; HYPERALGESIA; MALE; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR OCCUPANCY;

EID: 84855594373     PISSN: 16876334     EISSN: 16876342     Source Type: Journal    
DOI: 10.1155/2011/608912     Document Type: Article

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